Diazinon, chlorpyrifos and parathion are metabolised by multiple cytochromes P450 in human liver

Toxicology

Volumn 224, Issue 1-2, 2006, Pages 22-32

  Mutch, Elaine ^a   Williams, Faith M ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Human CYPs; Human liver; Metabolism; Organophosphate pesticides

Indexed keywords

4 NITROPHENOL; CHLORPYRIFOS; CHLORPYRIFOS OXON; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2B6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; DIAZOXON; DIMPYLATE; ISOENZYME; PARATHION; PESTICIDE; PYRIMIDINE DERIVATIVE; PYRIMIDINOL; RECOMBINANT ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRICHLORO 2 PYRIDINOL; UNCLASSIFIED DRUG;

ARTICLE; ARYLATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DETOXIFICATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME METABOLISM; HUMAN; HUMAN TISSUE; LIVER METABOLISM; LIVER MICROSOME; METABOLITE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CHLORPYRIFOS; CYTOCHROME P-450 ENZYME SYSTEM; DIAZINON; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INSECTICIDES; ISOENZYMES; LIVER; MICROSOMES, LIVER; PARATHION; RECOMBINANT PROTEINS;

EID: 33745211682     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.04.024     Document Type: Article

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