Over-expression of leptin receptors in hypothalamic POMC neurons increases susceptibility to diet-induced obesity

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Gamber, Kevin M ^a   Huo, Lihong ^a   Ha, Sangdeuk ^a   Hairston, Joyce E ^a   Greeley, Sarah ^a   Bjørbæk, Christian ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN RECEPTOR; MESSENGER RNA; PROOPIOMELANOCORTIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; SOCS3 PROTEIN, MOUSE; STAT3 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; BRAIN NERVE CELL; CALORIC INTAKE; CONTROLLED STUDY; DISEASE PREDISPOSITION; FOOD INTAKE; GENE OVEREXPRESSION; GENETIC SUSCEPTIBILITY; HYPOTHALAMUS; LIPID DIET; LOW FAT DIET; MALE; MOUSE; NONHUMAN; OBESITY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; BODY COMPOSITION; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; CYTOLOGY; GENETICS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; METABOLISM; NERVE CELL; PHOSPHORYLATION;

MUS; RODENTIA;

ANIMALS; BODY COMPOSITION; DIET, FAT-RESTRICTED; DIET, HIGH-FAT; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICE; MICE, INBRED C57BL; NEURONS; OBESITY; PHOSPHORYLATION; PRO-OPIOMELANOCORTIN; RECEPTORS, LEPTIN; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84856036647     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030485     Document Type: Article

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