The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation

Biochemical and Biophysical Research Communications

Volumn 297, Issue 4, 2002, Pages 811-817

  Yamamoto, Tetsuya ^a,b   Sekine, Yuichi ^a   Kashima, Keiichi ^a   Kubota, Atsuko ^a   Sato, Noriko ^a   Aoki, Naohito ^c   Matsuda, Tadashi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b TOYAMA CHEMICAL CO LTD   (Japan)

^c NAGOYA UNIVERSITY   (Japan)

Author keywords

IL 6; Leukemia inhibitory factor (LIF); Signal transducer and activator of transcription (STAT3); T cell protein tyrosine phosphatase (TC PTP)

Indexed keywords

INTERLEUKIN 6; ISOPROTEIN; MUTANT PROTEIN; PROTEIN TYROSINE PHOSPHATASE; RETROVIRUS VECTOR; STAT3 PROTEIN;

ANIMAL CELL; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL NUCLEUS; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; LEUKEMIA CELL; MYELOID LEUKEMIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TRANSCRIPTION INITIATION;

ACUTE-PHASE PROTEINS; ANIMALS; CELL DIVISION; CELL LINE; CELL NUCLEUS; DNA-BINDING PROTEINS; GENES, REPORTER; HUMANS; INTERLEUKIN-6; ISOENZYMES; KINETICS; LUCIFERASES; MICE; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PROTEIN-TYROSINE-PHOSPHATASE; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; SUBSTRATE SPECIFICITY; TRANS-ACTIVATORS; TRANSFECTION; TUMOR CELLS, CULTURED;

UNIDENTIFIED RETROVIRUS;

EID: 0036033161     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)02291-X     Document Type: Article

References (39)

1. T. Kishimoto, S. Akira, T. Taga, Interleukin-6 and its receptor: a paradigm for cytokines, Science 258 (1992) 593-597.
2. T. Matsuda, T. Hirano, in: J.J. Oppenheim, M. Feldmann (Eds.), Interleukin 6 in Cytokine Reference, Academic Press, London, 2000, pp. 537-563.
3. T. Hirano, K. Nakajima, M. Hibi, Signaling mechanisms through gp130: a model of the cytokine system, Cytokine Growth Factor Rev. 8 (1997) 241-252.
4. T. Kishimoto, T. Taga, S. Akira, Cytokine signal transduction, Cell 76 (1994) 253-262.
5. J.N. Ihle, Cytokine receptor signaling, Nature 377 (1995) 591-594.
6. J.E. Darnell, I.M. Kerr, G.R. Stark, Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins, Science 264 (1994) 1415-1421.
7. B.G. Neel, N.K. Tonks, Protein tyrosine phosphatases in signal transduction, Curr. Opin. Cell Biol. 9 (1997) 193-204.
8. N.K. Tonks, B.G. Neel, Combinatorial control of the specificity of protein tyrosine phosphatases, Curr. Opin. Cell Biol. 13 (2001) 182-195.
9. D.E. Cool, N.K. Tonks, H. Charbonneau, K.A. Walsh, E.. Fischer, E.G. Krebs, cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family, Proc. Natl. Acad. Sci. USA 86 (1989) 5257-5261.
10. D.E. Cool, N.K. Tonks, H. Charbonneau, E.H. Fischer, E.G. Krebs, Expression of a human T-cell protein-tyrosine-phosphatase in baby hamster kidney cells, Proc. Natl. Acad. Sci. USA 87 (1990) 7280-7284.
11. B. Mosinger Jr., U. Tillmann, H. Westphal, M.L. Tremblay, Cloning and characterization of a mouse cDNA encoding a cytoplasmic protein-tyrosine-phosphatase, Proc. Natl. Acad. Sci. USA 89 (1992) 499-503.
12. P. Champion-Arnaud, M.C. Gesnel, N. Foulkes, C. Ronsin, P. Sassone-Corsi, R. Breathnach, Activation of transcription via AP-1 or CREB regulatory sites is blocked by protein tyrosine phosphatases, Oncogene 6 (1991) 1203-1209.
13. U. Tillmann, J. Wagner, D. Boerboom, H. Westphal, M.L. Tremblay, Nuclear localization and cell cycle regulation of a murine protein tyrosine phosphatase, Mol. Cell. Biol. 14 (1994) 3030-3040.
14. M.H.C. Lam, B.J. Michell, M.T. Fodero-Tavoletti, B.E. Kemp, N.K. Tonks, T. Tiganis, Cellular stress regulates the nucleocytoplasmic distribution of the protein-tyrosine phosphatase TCPTP, J. Biol. Chem. 276 (2001) 37700-37707.
15. K.E. You-Ten, E.S. Muise, A. Itie, E. Michaliszyn, J. Wagner, S. Jothy, W.S. Lapp, M.L. Tremblay, Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient mice, J. Exp. Med. 186 (1997) 683-693.
16. N. Aoki, T. Matsuda, A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b, J. Biol. Chem. 275 (2000) 39718-39726.
17. N. Aoki, T. Matsuda, A nuclear protein tyrosine phosphatase TC-PTP is a potential negative regulator of the PRL-mediated signaling pathway: dephosphorylation and deactivation of signal transducer and activator of transcription 5a and 5b by TC-PTP in nucleus, Mol. Endocrinol. 16 (2002) 58-69.
18. K. Nakajima, Y. Yamanaka, K. Nakae, H. Kojima, M. Ichiba, N. Kiuchi, T. Kitaoka, T. Fukada, M. Hibi, T. Hirano, A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells, EMBO J. 15 (1996) 3651-3658.
19. T. Yamamoto, T. Matsuda, A. Junicho, H. Kishi, F. Saatcioglu, A. Muraguchi, Cross-talk between signal transducer and activator of transcription 3 and estrogen receptor signaling, FEBS Lett. 486 (2000) 143-148.
20. S. Morita, T. Kojima, T. Kitamura, Plat-E: an efficient and stable system for transient packaging of retroviruses, Gene Therapy 7 (2000) 1063-1066.
21. T. Matsuda, T. Yamamoto, H. Kishi, A. Yoshimura, A. Muraguchi, SOCS-1 can suppress CD3zeta- and Syk-mediated NF-AT activation in a non-lymphoid cell line, FEBS Lett. 472 (2000) 235-240.
22. D. Bandyopadhyay, M. Mandal, L. Adam, J. Mendelsohn, R. Kumar, Physical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cells, J. Biol. Chem. 273 (1998) 1568-1573.
23. T. Taga, M. Hibi, Y. Hirata, K. Yamasaki, K. Yasukawa, T. Matsuda, T. Hirano, T. Kishimoto, Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130, Cell 58 (1989) 573-581.
24. T. Tiganis, A.M. Bennett, K.S. Ravichandran, N.K. Tonks, Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase, Mol. Cell. Biol. 18 (1998) 1622-1634.
25. R. Starr, T.A. Willson, E.M. Viney, L.J. Murray, J.R. Rayner, B.J. Jenkins, T.J. Gonda, W.S. Alexander, D. Metcalf, N.A. Nicola, D.J. Hilton, A family of cytokine-inducible inhibitors of signaling, Nature 387 (1997) 917-921.
26. T. Endo, A. Masuhara, M. Yokouchi, R. Suzuki, H. Sakamoto, K. Mitsui, A. Matsumoto, S. Tanimura, M. Ohtsubo, H. Misawa, T. Miyazaki, N. Leonor, T. Taniguchi, T. Fujita, Y. Kanakura, S. Komiya, A. Yoshimura, A new protein containing an SH2 domain that inhibits JAK kinases, Nature 387 (1997) 921-924.
27. T. Naka, M. Narazaki, M. Hirata, T. Matsumoto, S. Minamoto, A. Aono, N. Nishimoto, T. Kajita, T. Taga, K. Yoshizaki, S. Akiraand, T. Kishimoto, Structure and function of a new STAT-induced STAT inhibitor, Nature 387 (1997) 924-929.
28. C.D. Chung, J. Liao, B. Liu, X. Rao, P. Jay, P. Berta, K. Shuai, Specific inhibition of Stat3 signal transduction by PIAS3, Science 278 (1997) 1803-1805.
29. H. Kim, T.S. Hawley, R.G. Hawley, H. Baumann, Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells, Mol. Cell. Biol. 18 (1998) 1525-1533.
30. F. Schaper, C. Gendo, M. Eck, J. Schmitz, C. Grimm, D. Anhuf, I.M. Kerr, P.C. Heinrich, Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression, Biochem. J. 335 (1998) 557-565.
31. M. You, D.H. Yu, G.S. Feng, Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway, Mol. Cell. Biol. 19 (1999) 2416-2424.
32. H. Kim, H. Baumann, Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells, Mol. Cell. Biol. 19 (1999) 5326-5338.
33. Deleted in proof.
34. N. Tanuma, K. Nakamura, H. Shima, K. Kikuchi, Protein-tyrosine phosphatase PTPepsilon C inhibits Jak-STAT signaling and differentiation induced by interleukin-6 and leukemia inhibitory factor in M1 leukemia cells, J. Biol. Chem. 275 (2000) 28216-28221.
35. N. Tanuma, H. Shima, K. Nakamura, K. Kikuchi, Protein tyrosine phosphatase εC selectively inhibits interleukin-6- and interleukin-10-induced JAK-STAT signaling, Blood 98 (2001) 3030-3034.
36. M.P. Myers, J.N. Andersen, A. Cheng, M.L. Tremblay, C.M. Horvath, J.P. Parisien, A. Salmeen, D. Barford, N.K. Tonks, TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B, J. Biol. Chem. 276 (2001) 47771-47774.
37. B.L. Seely, P.A. Staubs, D.R. Reichart, P. Berhanu, K.L. Milarski, A.R. Saltiel, J. Kusari, J.M. Olefsky, Protein tyrosine phosphatase 1B interacts with the activated insulin receptor, Diabetes 45 (1996) 1379-1385.
38. D. Bandyopadhyay, A. Kusari, K.A. Kenner, F. Liu, J. Chernoff, T.A. Gustafson, J. Kusari, Protein-tyrosine phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin, J. Biol. Chem. 272 (1997) 1639-1645.
39. M. Elchebly, P. Payette, E. Michaliszyn, W. Cromlish, S. Collins, A.L. Loy, D. Normandin, A. Cheng, J. Himms-Hagen, C.C. Chan, C. Ramachandran, M.J. Gresser, M.L. Tremblay, B.P. Kennedy, Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene, Science 283 (1999) 1544-1548.