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Volumn 52, Issue 2, 2012, Pages 351-358

AKAPs: The architectural underpinnings of local cAMP signaling

Author keywords

AKAP; CAMP; Compartmentation; PKA; Scaffold; Signaling

Indexed keywords

CALCINEURIN; CALCIUM CHANNEL L TYPE; CALCIUM ION; CARRIER PROTEINS AND BINDING PROTEINS; CAVEOLIN 3; CONNECTIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN 13; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN 18; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN 6; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN 79; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN 9; HISTONE DEACETYLASE 5; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE 7; PHOSPHODIESTERASE III; PHOSPHODIESTERASE IV; PHOSPHOLAMBAN; POLYCYSTIN 1; PROTEIN 14 3 3; PROTEIN BCL 2; PROTEIN KINASE C; RAP1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RYANODINE RECEPTOR 2; TROPONIN I; UNCLASSIFIED DRUG;

EID: 84855998675     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2011.05.002     Document Type: Review
Times cited : (83)

References (109)
  • 1
    • 34447265905 scopus 로고    scopus 로고
    • Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling
    • Conti M., Beavo J. Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. Annu Rev Biochem 2007, 76:481-511.
    • (2007) Annu Rev Biochem , vol.76 , pp. 481-511
    • Conti, M.1    Beavo, J.2
  • 2
    • 54249153754 scopus 로고    scopus 로고
    • Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies
    • Sadana R., Dessauer C.W. Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies. Neurosignals 2009, 17(1):5-22.
    • (2009) Neurosignals , vol.17 , Issue.1 , pp. 5-22
    • Sadana, R.1    Dessauer, C.W.2
  • 3
    • 0018948046 scopus 로고
    • Selective activation of particulate cAMP-dependent protein kinase by isoproterenol and prostaglandin E1
    • Hayes J.S., Brunton L.L., Mayer S.E. Selective activation of particulate cAMP-dependent protein kinase by isoproterenol and prostaglandin E1. J Biol Chem 1980, 255(11):5113-5119.
    • (1980) J Biol Chem , vol.255 , Issue.11 , pp. 5113-5119
    • Hayes, J.S.1    Brunton, L.L.2    Mayer, S.E.3
  • 4
    • 0017752640 scopus 로고
    • Activation of cAMP-dependent protein kinase without a corresponding increase in phosphorylase activity
    • Keely S.L. Activation of cAMP-dependent protein kinase without a corresponding increase in phosphorylase activity. Res Commun Chem Pathol Pharmacol 1977, 18(2):283-290.
    • (1977) Res Commun Chem Pathol Pharmacol , vol.18 , Issue.2 , pp. 283-290
    • Keely, S.L.1
  • 6
    • 36749006297 scopus 로고    scopus 로고
    • Spatiotemporal control of cAMP signalling processes by anchored signalling complexes
    • Jarnaess E., Tasken K. Spatiotemporal control of cAMP signalling processes by anchored signalling complexes. Biochem Soc Trans 2007 Nov, 35(Pt 5):931-937.
    • (2007) Biochem Soc Trans , vol.35 , Issue.PART 5 , pp. 931-937
    • Jarnaess, E.1    Tasken, K.2
  • 7
    • 33745181698 scopus 로고    scopus 로고
    • The where's and when's of kinase anchoring
    • Smith F.D., Langeberg L.K., Scott J.D. The where's and when's of kinase anchoring. Trends Biochem Sci 2006 Jun, 31(6):316-323.
    • (2006) Trends Biochem Sci , vol.31 , Issue.6 , pp. 316-323
    • Smith, F.D.1    Langeberg, L.K.2    Scott, J.D.3
  • 8
    • 67650394253 scopus 로고    scopus 로고
    • A-kinase anchoring proteins: from protein complexes to physiology and disease
    • Carnegie G.K., Means C.K., Scott J.D. A-kinase anchoring proteins: from protein complexes to physiology and disease. IUBMB Life 2009 Apr, 61(4):394-406.
    • (2009) IUBMB Life , vol.61 , Issue.4 , pp. 394-406
    • Carnegie, G.K.1    Means, C.K.2    Scott, J.D.3
  • 9
    • 77951985322 scopus 로고    scopus 로고
    • AKAP79 interacts with multiple adenylyl cyclase (AC) isoforms and scaffolds AC5 and -6 to alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptors
    • Efendiev R., Samelson B.K., Nguyen B.T., Phatarpekar P.V., Baameur F., Scott J.D., et al. AKAP79 interacts with multiple adenylyl cyclase (AC) isoforms and scaffolds AC5 and -6 to alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptors. J Biol Chem 2010 May 7, 285(19):14450-14458.
    • (2010) J Biol Chem , vol.285 , Issue.19 , pp. 14450-14458
    • Efendiev, R.1    Samelson, B.K.2    Nguyen, B.T.3    Phatarpekar, P.V.4    Baameur, F.5    Scott, J.D.6
  • 10
    • 25644452031 scopus 로고    scopus 로고
    • The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways
    • Dodge-Kafka K.L., Soughayer J., Pare G.C., Carlisle Michel J.J., Langeberg L.K., Kapiloff M.S., et al. The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways. Nature 2005 Sep 22, 437(7058):574-578.
    • (2005) Nature , vol.437 , Issue.7058 , pp. 574-578
    • Dodge-Kafka, K.L.1    Soughayer, J.2    Pare, G.C.3    Carlisle Michel, J.J.4    Langeberg, L.K.5    Kapiloff, M.S.6
  • 11
    • 33744981419 scopus 로고    scopus 로고
    • Phosphodiesterases and compartmentalized cAMP signalling in the heart
    • Zaccolo M. Phosphodiesterases and compartmentalized cAMP signalling in the heart. Eur J Cell Biol 2006 Jul, 85(7):693-697.
    • (2006) Eur J Cell Biol , vol.85 , Issue.7 , pp. 693-697
    • Zaccolo, M.1
  • 12
    • 69249211018 scopus 로고    scopus 로고
    • CAMP signal transduction in the heart: understanding spatial control for the development of novel therapeutic strategies
    • Zaccolo M. cAMP signal transduction in the heart: understanding spatial control for the development of novel therapeutic strategies. Br J Pharmacol 2009 Sep, 158(1):50-60.
    • (2009) Br J Pharmacol , vol.158 , Issue.1 , pp. 50-60
    • Zaccolo, M.1
  • 13
    • 0030025596 scopus 로고    scopus 로고
    • CAMP compartmentation is responsible for a local activation of cardiac Ca2+ channels by beta-adrenergic agonists
    • Jurevicius J., Fischmeister R. cAMP compartmentation is responsible for a local activation of cardiac Ca2+ channels by beta-adrenergic agonists. Proc Natl Acad Sci U S A 1996, 93(1):295-299.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , Issue.1 , pp. 295-299
    • Jurevicius, J.1    Fischmeister, R.2
  • 14
    • 33646776455 scopus 로고    scopus 로고
    • A specific pattern of phosphodiesterases controls the cAMP signals generated by different Gs-coupled receptors in adult rat ventricular myocytes
    • Rochais F., Abi-Gerges A., Horner K., Lefebvre F., Cooper D.M., Conti M., et al. A specific pattern of phosphodiesterases controls the cAMP signals generated by different Gs-coupled receptors in adult rat ventricular myocytes. Circ Res 2006 Apr 28, 98(8):1081-1088.
    • (2006) Circ Res , vol.98 , Issue.8 , pp. 1081-1088
    • Rochais, F.1    Abi-Gerges, A.2    Horner, K.3    Lefebvre, F.4    Cooper, D.M.5    Conti, M.6
  • 15
    • 3142723295 scopus 로고    scopus 로고
    • Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases
    • Mongillo M., McSorley T., Evellin S., Sood A., Lissandron V., Terrin A., et al. Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases. Circ Res 2004 Jul 9, 95(1):67-75.
    • (2004) Circ Res , vol.95 , Issue.1 , pp. 67-75
    • Mongillo, M.1    McSorley, T.2    Evellin, S.3    Sood, A.4    Lissandron, V.5    Terrin, A.6
  • 16
    • 34247105883 scopus 로고    scopus 로고
    • CAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling
    • Houslay M.D., Baillie G.S., Maurice D.H. cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling. Circ Res 2007 Apr 13, 100(7):950-966.
    • (2007) Circ Res , vol.100 , Issue.7 , pp. 950-966
    • Houslay, M.D.1    Baillie, G.S.2    Maurice, D.H.3
  • 17
    • 33750910207 scopus 로고    scopus 로고
    • Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling
    • Nikolaev V.O., Bunemann M., Schmitteckert E., Lohse M.J., Engelhardt S. Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling. Circ Res 2006 Nov 10, 99(10):1084-1091.
    • (2006) Circ Res , vol.99 , Issue.10 , pp. 1084-1091
    • Nikolaev, V.O.1    Bunemann, M.2    Schmitteckert, E.3    Lohse, M.J.4    Engelhardt, S.5
  • 18
    • 77950286813 scopus 로고    scopus 로고
    • Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation
    • Nikolaev V.O., Moshkov A., Lyon A.R., Miragoli M., Novak P., Paur H., et al. Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation. Science 2010 Mar 26, 327(5973):1653-1657.
    • (2010) Science , vol.327 , Issue.5973 , pp. 1653-1657
    • Nikolaev, V.O.1    Moshkov, A.2    Lyon, A.R.3    Miragoli, M.4    Novak, P.5    Paur, H.6
  • 19
    • 0025810398 scopus 로고
    • Cyclic nucleotide-dependent protein kinases
    • Scott J.D. Cyclic nucleotide-dependent protein kinases. Pharmacol Ther 1991, 50(1):123-145.
    • (1991) Pharmacol Ther , vol.50 , Issue.1 , pp. 123-145
    • Scott, J.D.1
  • 20
    • 54449097985 scopus 로고    scopus 로고
    • Protein kinase A type I and type II define distinct intracellular signaling compartments
    • Di Benedetto G., Zoccarato A., Lissandron V., Terrin A., Li X., Houslay M.D., et al. Protein kinase A type I and type II define distinct intracellular signaling compartments. Circ Res 2008 Oct 10, 103(8):836-844.
    • (2008) Circ Res , vol.103 , Issue.8 , pp. 836-844
    • Di Benedetto, G.1    Zoccarato, A.2    Lissandron, V.3    Terrin, A.4    Li, X.5    Houslay, M.D.6
  • 21
    • 0017684387 scopus 로고
    • Compartmentalization of adenosine 3':5'-monophosphate and adenosine 3':5'-monophosphate-dependent protein kinase in heart tissue
    • Corbin J.D., Sugden P.H., Lincoln T.M., Keely S.L. Compartmentalization of adenosine 3':5'-monophosphate and adenosine 3':5'-monophosphate-dependent protein kinase in heart tissue. J Biol Chem 1977, 252(11):3854-3861.
    • (1977) J Biol Chem , vol.252 , Issue.11 , pp. 3854-3861
    • Corbin, J.D.1    Sugden, P.H.2    Lincoln, T.M.3    Keely, S.L.4
  • 22
    • 0021023294 scopus 로고
    • Compartments of cyclic AMP and protein kinase in mammalian cardiomyocytes
    • Buxton I.L., Brunton L.L. Compartments of cyclic AMP and protein kinase in mammalian cardiomyocytes. J Biol Chem 1983, 258(17):10233-10239.
    • (1983) J Biol Chem , vol.258 , Issue.17 , pp. 10233-10239
    • Buxton, I.L.1    Brunton, L.L.2
  • 23
    • 55949130303 scopus 로고    scopus 로고
    • Selective coupling of type 6 adenylyl cyclase with type 2 IP3 receptors mediates direct sensitization of IP3 receptors by cAMP
    • Tovey S.C., Dedos S.G., Taylor E.J., Church J.E., Taylor C.W. Selective coupling of type 6 adenylyl cyclase with type 2 IP3 receptors mediates direct sensitization of IP3 receptors by cAMP. J Cell Biol 2008 Oct 20, 183(2):297-311.
    • (2008) J Cell Biol , vol.183 , Issue.2 , pp. 297-311
    • Tovey, S.C.1    Dedos, S.G.2    Taylor, E.J.3    Church, J.E.4    Taylor, C.W.5
  • 24
    • 70350469968 scopus 로고    scopus 로고
    • Adenylyl cyclase-A-kinase anchoring protein complexes: the next dimension in cAMP signaling
    • Dessauer C.W. Adenylyl cyclase-A-kinase anchoring protein complexes: the next dimension in cAMP signaling. Mol Pharmacol 2009 Nov, 76(5):935-941.
    • (2009) Mol Pharmacol , vol.76 , Issue.5 , pp. 935-941
    • Dessauer, C.W.1
  • 26
    • 69949130120 scopus 로고    scopus 로고
    • An adenylyl cyclase-mAKAPbeta signaling complex regulates cAMP levels in cardiac myocytes
    • Kapiloff M.S., Piggott L.A., Sadana R., Li J., Heredia L.A., Henson E., et al. An adenylyl cyclase-mAKAPbeta signaling complex regulates cAMP levels in cardiac myocytes. J Biol Chem 2009 Aug 28, 284(35):23540-23546.
    • (2009) J Biol Chem , vol.284 , Issue.35 , pp. 23540-23546
    • Kapiloff, M.S.1    Piggott, L.A.2    Sadana, R.3    Li, J.4    Heredia, L.A.5    Henson, E.6
  • 27
    • 0033835813 scopus 로고    scopus 로고
    • Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase
    • Defer N., Best-Belpomme M., Hanoune J. Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase. Am J Physiol Renal Physiol 2000 Sep, 279(3):F400-F416.
    • (2000) Am J Physiol Renal Physiol , vol.279 , Issue.3
    • Defer, N.1    Best-Belpomme, M.2    Hanoune, J.3
  • 28
    • 34447510936 scopus 로고    scopus 로고
    • Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains
    • Willoughby D., Cooper D.M. Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains. Physiol Rev 2007 Jul, 87(3):965-1010.
    • (2007) Physiol Rev , vol.87 , Issue.3 , pp. 965-1010
    • Willoughby, D.1    Cooper, D.M.2
  • 29
    • 77949908921 scopus 로고    scopus 로고
    • Adenylyl cyclase 6 deletion reduces left ventricular hypertrophy, dilation, dysfunction, and fibrosis in pressure-overloaded female mice
    • Tang T., Lai N.C., Hammond H.K., Roth D.M., Yang Y., Guo T., et al. Adenylyl cyclase 6 deletion reduces left ventricular hypertrophy, dilation, dysfunction, and fibrosis in pressure-overloaded female mice. J Am Coll Cardiol 2010 Apr 6, 55(14):1476-1486.
    • (2010) J Am Coll Cardiol , vol.55 , Issue.14 , pp. 1476-1486
    • Tang, T.1    Lai, N.C.2    Hammond, H.K.3    Roth, D.M.4    Yang, Y.5    Guo, T.6
  • 30
    • 0042691820 scopus 로고    scopus 로고
    • Disruption of type 5 adenylyl cyclase gene preserves cardiac function against pressure overload
    • Okumura S., Takagi G., Kawabe J., Yang G., Lee M.C., Hong C., et al. Disruption of type 5 adenylyl cyclase gene preserves cardiac function against pressure overload. Proc Natl Acad Sci U S A 2003 Aug 19, 100(17):9986-9990.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.17 , pp. 9986-9990
    • Okumura, S.1    Takagi, G.2    Kawabe, J.3    Yang, G.4    Lee, M.C.5    Hong, C.6
  • 31
    • 77957256718 scopus 로고    scopus 로고
    • Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels
    • Nichols C.B., Rossow C.F., Navedo M.F., Westenbroek R.E., Catterall W.A., Santana L.F., et al. Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels. Circ Res 2010 Sep 17, 107(6):747-756.
    • (2010) Circ Res , vol.107 , Issue.6 , pp. 747-756
    • Nichols, C.B.1    Rossow, C.F.2    Navedo, M.F.3    Westenbroek, R.E.4    Catterall, W.A.5    Santana, L.F.6
  • 32
    • 38149061122 scopus 로고    scopus 로고
    • Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design
    • Taylor S.S., Kim C., Cheng C.Y., Brown S.H., Wu J., Kannan N. Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design. Biochim Biophys Acta 2008 Jan, 1784(1):16-26.
    • (2008) Biochim Biophys Acta , vol.1784 , Issue.1 , pp. 16-26
    • Taylor, S.S.1    Kim, C.2    Cheng, C.Y.3    Brown, S.H.4    Wu, J.5    Kannan, N.6
  • 33
    • 75849127506 scopus 로고    scopus 로고
    • Structure of D-AKAP2:PKA RI complex: insights into AKAP specificity and selectivity
    • Sarma G.N., Kinderman F.S., Kim C., von Daake S., Chen L., Wang B.C., et al. Structure of D-AKAP2:PKA RI complex: insights into AKAP specificity and selectivity. Structure 2010 Feb 10, 18(2):155-166.
    • (2010) Structure , vol.18 , Issue.2 , pp. 155-166
    • Sarma, G.N.1    Kinderman, F.S.2    Kim, C.3    von Daake, S.4    Chen, L.5    Wang, B.C.6
  • 34
    • 0032972739 scopus 로고    scopus 로고
    • The molecular basis for protein kinase A anchoring revealed by solution NMR
    • Newlon M.G., Roy M., Morikis D., Hausken Z.E., Coghlan V., Scott J.D., et al. The molecular basis for protein kinase A anchoring revealed by solution NMR. Nat Struct Biol 1999, 6(3):222-227.
    • (1999) Nat Struct Biol , vol.6 , Issue.3 , pp. 222-227
    • Newlon, M.G.1    Roy, M.2    Morikis, D.3    Hausken, Z.E.4    Coghlan, V.5    Scott, J.D.6
  • 35
    • 0037675779 scopus 로고    scopus 로고
    • Related protein-protein interaction modules present drastically different surface topographies despite a conserved helical platform
    • Banky P., Roy M., Newlon M.G., Morikis D., Haste N.M., Taylor S.S., et al. Related protein-protein interaction modules present drastically different surface topographies despite a conserved helical platform. J Mol Biol 2003 Jul 25, 330(5):1117-1129.
    • (2003) J Mol Biol , vol.330 , Issue.5 , pp. 1117-1129
    • Banky, P.1    Roy, M.2    Newlon, M.G.3    Morikis, D.4    Haste, N.M.5    Taylor, S.S.6
  • 36
    • 33750480828 scopus 로고    scopus 로고
    • Molecular basis of AKAP specificity for PKA regulatory subunits
    • Gold M.G., Lygren B., Dokurno P., Hoshi N., McConnachie G., Tasken K., et al. Molecular basis of AKAP specificity for PKA regulatory subunits. Mol Cell 2006 Nov 3, 24(3):383-395.
    • (2006) Mol Cell , vol.24 , Issue.3 , pp. 383-395
    • Gold, M.G.1    Lygren, B.2    Dokurno, P.3    Hoshi, N.4    McConnachie, G.5    Tasken, K.6
  • 37
    • 33746362123 scopus 로고    scopus 로고
    • Delineation of type I protein kinase A-selective signaling events using an RI anchoring disruptor
    • Carlson C.R., Lygren B., Berge T., Hoshi N., Wong W., Tasken K., et al. Delineation of type I protein kinase A-selective signaling events using an RI anchoring disruptor. J Biol Chem 2006 Jul 28, 281(30):21535-21545.
    • (2006) J Biol Chem , vol.281 , Issue.30 , pp. 21535-21545
    • Carlson, C.R.1    Lygren, B.2    Berge, T.3    Hoshi, N.4    Wong, W.5    Tasken, K.6
  • 38
    • 70350674150 scopus 로고    scopus 로고
    • Design of proteolytically stable RI-anchoring disruptor peptidomimetics for in vivo studies of anchored type I protein kinase A-mediated signalling
    • Torheim E.A., Jarnaess E., Lygren B., Tasken K. Design of proteolytically stable RI-anchoring disruptor peptidomimetics for in vivo studies of anchored type I protein kinase A-mediated signalling. Biochem J 2009 Nov 15, 424(1):69-78.
    • (2009) Biochem J , vol.424 , Issue.1 , pp. 69-78
    • Torheim, E.A.1    Jarnaess, E.2    Lygren, B.3    Tasken, K.4
  • 39
    • 0035895592 scopus 로고    scopus 로고
    • AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes
    • Fink M.A., Zakhary D.R., Mackey J.A., Desnoyer R.W., Apperson-Hansen C., Damron D.S., et al. AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes. Circ Res 2001 Feb 16, 88(3):291-297.
    • (2001) Circ Res , vol.88 , Issue.3 , pp. 291-297
    • Fink, M.A.1    Zakhary, D.R.2    Mackey, J.A.3    Desnoyer, R.W.4    Apperson-Hansen, C.5    Damron, D.S.6
  • 40
    • 59449102704 scopus 로고    scopus 로고
    • Disruption of protein kinase A interaction with A-kinase-anchoring proteins in the heart in vivo: effects on cardiac contractility, protein kinase A phosphorylation, and troponin I proteolysis
    • McConnell B.K., Popovic Z., Mal N., Lee K., Bautista J., Forudi F., et al. Disruption of protein kinase A interaction with A-kinase-anchoring proteins in the heart in vivo: effects on cardiac contractility, protein kinase A phosphorylation, and troponin I proteolysis. J Biol Chem 2009 Jan 16, 284(3):1583-1592.
    • (2009) J Biol Chem , vol.284 , Issue.3 , pp. 1583-1592
    • McConnell, B.K.1    Popovic, Z.2    Mal, N.3    Lee, K.4    Bautista, J.5    Forudi, F.6
  • 41
    • 77956239101 scopus 로고    scopus 로고
    • Disruption of protein kinase A localization using a trans-activator of transcription (TAT)-conjugated A-kinase-anchoring peptide reduces cardiac function
    • Patel H.H., Hamuro L.L., Chun B.J., Kawaraguchi Y., Quick A., Rebolledo B., et al. Disruption of protein kinase A localization using a trans-activator of transcription (TAT)-conjugated A-kinase-anchoring peptide reduces cardiac function. J Biol Chem 2010 Sep 3, 285(36):27632-27640.
    • (2010) J Biol Chem , vol.285 , Issue.36 , pp. 27632-27640
    • Patel, H.H.1    Hamuro, L.L.2    Chun, B.J.3    Kawaraguchi, Y.4    Quick, A.5    Rebolledo, B.6
  • 42
    • 0026795614 scopus 로고
    • Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79
    • Carr D.W., Stofko-Hahn R.E., Fraser I.D., Cone R.D., Scott J.D. Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79. J Biol Chem 1992, 267(24):16816-16823.
    • (1992) J Biol Chem , vol.267 , Issue.24 , pp. 16816-16823
    • Carr, D.W.1    Stofko-Hahn, R.E.2    Fraser, I.D.3    Cone, R.D.4    Scott, J.D.5
  • 43
    • 0032522719 scopus 로고    scopus 로고
    • Membrane-targeting sequences on AKAP79 bind phosphatidylinositol-4, 5-bisphosphate
    • Dell'Acqua M.L., Faux M.C., Thorburn J., Thorburn A., Scott J.D. Membrane-targeting sequences on AKAP79 bind phosphatidylinositol-4, 5-bisphosphate. EMBO J 1998, 17(8):2246-2260.
    • (1998) EMBO J , pp. 2246-2260
    • Dell'Acqua, M.L.1    Faux, M.C.2    Thorburn, J.3    Thorburn, A.4    Scott, J.D.5
  • 45
    • 77956413047 scopus 로고    scopus 로고
    • Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice
    • Weisenhaus M., Allen M.L., Yang L., Lu Y., Nichols C.B., Su T., et al. Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice. PLoS One 2010, 5(4):e10325.
    • (2010) PLoS One , vol.5 , Issue.4
    • Weisenhaus, M.1    Allen, M.L.2    Yang, L.3    Lu, Y.4    Nichols, C.B.5    Su, T.6
  • 46
    • 0034611757 scopus 로고    scopus 로고
    • Assembly of an A kinase-anchoring protein-beta(2)-adrenergic receptor complex facilitates receptor phosphorylation and signaling
    • Fraser I.D., Cong M., Kim J., Rollins E.N., Daaka Y., Lefkowitz R.J., et al. Assembly of an A kinase-anchoring protein-beta(2)-adrenergic receptor complex facilitates receptor phosphorylation and signaling. Curr Biol 2000, 10(7):409-412.
    • (2000) Curr Biol , vol.10 , Issue.7 , pp. 409-412
    • Fraser, I.D.1    Cong, M.2    Kim, J.3    Rollins, E.N.4    Daaka, Y.5    Lefkowitz, R.J.6
  • 47
    • 33845945668 scopus 로고    scopus 로고
    • AKAP79-mediated targeting of the cyclic AMP-dependent protein kinase to the beta1-adrenergic receptor promotes recycling and functional resensitization of the receptor
    • Gardner L.A., Tavalin S.J., Goehring A.S., Scott J.D., Bahouth S.W. AKAP79-mediated targeting of the cyclic AMP-dependent protein kinase to the beta1-adrenergic receptor promotes recycling and functional resensitization of the receptor. J Biol Chem 2006 Nov 3, 281(44):33537-33553.
    • (2006) J Biol Chem , vol.281 , Issue.44 , pp. 33537-33553
    • Gardner, L.A.1    Tavalin, S.J.2    Goehring, A.S.3    Scott, J.D.4    Bahouth, S.W.5
  • 48
    • 0035805528 scopus 로고    scopus 로고
    • Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79
    • Cong M., Perry S.J., Lin F.T., Fraser I.D., Hu L.A., Chen W., et al. Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79. J Biol Chem 2001 May 4, 276(18):15192-15199.
    • (2001) J Biol Chem , vol.276 , Issue.18 , pp. 15192-15199
    • Cong, M.1    Perry, S.J.2    Lin, F.T.3    Fraser, I.D.4    Hu, L.A.5    Chen, W.6
  • 49
    • 33748521580 scopus 로고    scopus 로고
    • Dynamic regulation of cAMP synthesis through anchored PKA-adenylyl cyclase V/VI complexes
    • Bauman A.L., Soughayer J., Nguyen B.T., Willoughby D., Carnegie G.K., Wong W., et al. Dynamic regulation of cAMP synthesis through anchored PKA-adenylyl cyclase V/VI complexes. Mol Cell 2006 Sep 15, 23(6):925-931.
    • (2006) Mol Cell , vol.23 , Issue.6 , pp. 925-931
    • Bauman, A.L.1    Soughayer, J.2    Nguyen, B.T.3    Willoughby, D.4    Carnegie, G.K.5    Wong, W.6
  • 50
    • 33846950037 scopus 로고    scopus 로고
    • Organization of beta-adrenoceptor signaling compartments by sympathetic innervation of cardiac myocytes
    • Shcherbakova O.G., Hurt C.M., Xiang Y., Dell'Acqua M.L., Zhang Q., Tsien R.W., et al. Organization of beta-adrenoceptor signaling compartments by sympathetic innervation of cardiac myocytes. J Cell Biol 2007 Feb 12, 176(4):521-533.
    • (2007) J Cell Biol , pp. 521-533
    • Shcherbakova, O.G.1    Hurt, C.M.2    Xiang, Y.3    Dell'Acqua, M.L.4    Zhang, Q.5    Tsien, R.W.6
  • 52
    • 0030760304 scopus 로고    scopus 로고
    • CAMP-dependent regulation of cardiac L-type Ca2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits
    • Gao T., Yatani A., Dell'Acqua M.L., Sako H., Green S.A., Dascal N., et al. cAMP-dependent regulation of cardiac L-type Ca2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits. Neuron 1997, 19(1):185-196.
    • (1997) Neuron , pp. 185-196
    • Gao, T.1    Yatani, A.2    Dell'Acqua, M.L.3    Sako, H.4    Green, S.A.5    Dascal, N.6
  • 53
    • 34447283760 scopus 로고    scopus 로고
    • AKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signaling
    • Oliveria S.F., Dell'Acqua M.L., Sather W.A. AKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signaling. Neuron 2007 Jul 19, 55(2):261-275.
    • (2007) Neuron , pp. 261-275
    • Oliveria, S.F.1    Dell'Acqua, M.L.2    Sather, W.A.3
  • 54
    • 67649973701 scopus 로고    scopus 로고
    • Supramolecular assemblies and localized regulation of voltage-gated ion channels
    • Dai S., Hall D.D., Hell J.W. Supramolecular assemblies and localized regulation of voltage-gated ion channels. Physiol Rev 2009 Apr, 89(2):411-452.
    • (2009) Physiol Rev , vol.89 , Issue.2 , pp. 411-452
    • Dai, S.1    Hall, D.D.2    Hell, J.W.3
  • 55
    • 41149131839 scopus 로고    scopus 로고
    • AKAP150 is required for stuttering persistent Ca2+ sparklets and angiotensin II-induced hypertension
    • Navedo M.F., Nieves-Cintron M., Amberg G.C., Yuan C., Votaw V.S., Lederer W.J., et al. AKAP150 is required for stuttering persistent Ca2+ sparklets and angiotensin II-induced hypertension. Circ Res 2008 Feb 1, 102(2):e1-e11.
    • (2008) Circ Res , vol.102 , Issue.2
    • Navedo, M.F.1    Nieves-Cintron, M.2    Amberg, G.C.3    Yuan, C.4    Votaw, V.S.5    Lederer, W.J.6
  • 56
    • 2642705036 scopus 로고    scopus 로고
    • A novel lipid-anchored A-kinase anchoring protein facilitates cAMP-responsive membrane events
    • Fraser I.D., Tavalin S.J., Lester L.B., Langeberg L.K., Westphal A.M., Dean R.A., et al. A novel lipid-anchored A-kinase anchoring protein facilitates cAMP-responsive membrane events. EMBO J 1998 Apr 15, 17(8):2261-2272.
    • (1998) EMBO J , vol.17 , Issue.8 , pp. 2261-2272
    • Fraser, I.D.1    Tavalin, S.J.2    Lester, L.B.3    Langeberg, L.K.4    Westphal, A.M.5    Dean, R.A.6
  • 57
    • 2142850031 scopus 로고    scopus 로고
    • A novel leucine zipper targets AKAP15 and PKA to the C-terminus of theskeletal muscle Ca{super2+} channel and modulates its function
    • Hulme J.T., Ahn M., Hauschka S.D., Scheuer T., Catterall W.A. A novel leucine zipper targets AKAP15 and PKA to the C-terminus of theskeletal muscle Ca{super2+} channel and modulates its function. J Biol Chem 2001, 30:30.
    • (2001) J Biol Chem , vol.30 , pp. 30
    • Hulme, J.T.1    Ahn, M.2    Hauschka, S.D.3    Scheuer, T.4    Catterall, W.A.5
  • 58
    • 0032078084 scopus 로고    scopus 로고
    • Primary structure and function of an A kinase anchoring protein associated with calcium channels
    • Gray P.C., Johnson B.D., Westenbroek R.E., Hays L.G., Yates J.R., Scheuer T., et al. Primary structure and function of an A kinase anchoring protein associated with calcium channels. Neuron 1998, 20(5):1017-1026.
    • (1998) Neuron , vol.20 , Issue.5 , pp. 1017-1026
    • Gray, P.C.1    Johnson, B.D.2    Westenbroek, R.E.3    Hays, L.G.4    Yates, J.R.5    Scheuer, T.6
  • 59
  • 60
    • 0242331601 scopus 로고    scopus 로고
    • Beta-adrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15
    • Hulme J.T., Lin T.W., Westenbroek R.E., Scheuer T., Catterall W.A. Beta-adrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15. Proc Natl Acad Sci U S A 2003 Oct 28, 100(22):13093-13098.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.22 , pp. 13093-13098
    • Hulme, J.T.1    Lin, T.W.2    Westenbroek, R.E.3    Scheuer, T.4    Catterall, W.A.5
  • 62
    • 79952000271 scopus 로고    scopus 로고
    • The large isoforms of A-kinase anchoring protein 18 mediate the phosphorylation of inhibitor-1 by protein kinase A and the inhibition of protein phosphatase 1 activity
    • Singh A., Redden J.M., Kapiloff M.S., Dodge-Kafka K.L. The large isoforms of A-kinase anchoring protein 18 mediate the phosphorylation of inhibitor-1 by protein kinase A and the inhibition of protein phosphatase 1 activity. Mol Pharmacol 2011 Mar, 79(3):533-540.
    • (2011) Mol Pharmacol , vol.79 , Issue.3 , pp. 533-540
    • Singh, A.1    Redden, J.M.2    Kapiloff, M.S.3    Dodge-Kafka, K.L.4
  • 63
    • 67650710788 scopus 로고    scopus 로고
    • Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology
    • Nicolaou P., Hajjar R.J., Kranias E.G. Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology. J Mol Cell Cardiol 2009 Sep, 47(3):365-371.
    • (2009) J Mol Cell Cardiol , vol.47 , Issue.3 , pp. 365-371
    • Nicolaou, P.1    Hajjar, R.J.2    Kranias, E.G.3
  • 64
    • 0037127028 scopus 로고    scopus 로고
    • Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel
    • Marx S.O., Kurokawa J., Reiken S., Motoike H., D'Armiento J., Marks A.R., et al. Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel. Science 2002, 295(5554):496-499.
    • (2002) Science , vol.295 , Issue.5554 , pp. 496-499
    • Marx, S.O.1    Kurokawa, J.2    Reiken, S.3    Motoike, H.4    D'Armiento, J.5    Marks, A.R.6
  • 66
    • 66149127296 scopus 로고    scopus 로고
    • The cardiac IKs potassium channel macromolecular complex includes the phosphodiesterase PDE4D3
    • Terrenoire C., Houslay M.D., Baillie G.S., Kass R.S. The cardiac IKs potassium channel macromolecular complex includes the phosphodiesterase PDE4D3. J Biol Chem 2009 Apr 3, 284(14):9140-9146.
    • (2009) J Biol Chem , vol.284 , Issue.14 , pp. 9140-9146
    • Terrenoire, C.1    Houslay, M.D.2    Baillie, G.S.3    Kass, R.S.4
  • 67
    • 52949130234 scopus 로고    scopus 로고
    • The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain
    • Piggott L.A., Bauman A.L., Scott J.D., Dessauer C.W. The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain. Proc Natl Acad Sci U S A 2008 Sep 16, 105(37):13835-13840.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.37 , pp. 13835-13840
    • Piggott, L.A.1    Bauman, A.L.2    Scott, J.D.3    Dessauer, C.W.4
  • 68
    • 24744442589 scopus 로고    scopus 로고
    • Phosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channel
    • Chen L., Kurokawa J., Kass R.S. Phosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channel. J Biol Chem 2005 Sep 9, 280(36):31347-31352.
    • (2005) J Biol Chem , vol.280 , Issue.36 , pp. 31347-31352
    • Chen, L.1    Kurokawa, J.2    Kass, R.S.3
  • 71
    • 77956936247 scopus 로고    scopus 로고
    • Interactions with M-band titin and calpain 3 link myospryn (CMYA5) to tibial and limb-girdle muscular dystrophies
    • Sarparanta J., Blandin G., Charton K., Vihola A., Marchand S., Milic A., et al. Interactions with M-band titin and calpain 3 link myospryn (CMYA5) to tibial and limb-girdle muscular dystrophies. J Biol Chem 2010 Sep 24, 285(39):30304-30315.
    • (2010) J Biol Chem , vol.285 , Issue.39 , pp. 30304-30315
    • Sarparanta, J.1    Blandin, G.2    Charton, K.3    Vihola, A.4    Marchand, S.5    Milic, A.6
  • 72
    • 38749152910 scopus 로고    scopus 로고
    • Gene polymorphism of myospryn (cardiomyopathy-associated 5) is associated with left ventricular wall thickness in patients with hypertension
    • Nakagami H., Kikuchi Y., Katsuya T., Morishita R., Akasaka H., Saitoh S., et al. Gene polymorphism of myospryn (cardiomyopathy-associated 5) is associated with left ventricular wall thickness in patients with hypertension. Hypertens Res 2007 Dec, 30(12):1239-1246.
    • (2007) Hypertens Res , vol.30 , Issue.12 , pp. 1239-1246
    • Nakagami, H.1    Kikuchi, Y.2    Katsuya, T.3    Morishita, R.4    Akasaka, H.5    Saitoh, S.6
  • 73
    • 77950638532 scopus 로고    scopus 로고
    • The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice
    • Mayers C.M., Wadell J., McLean K., Venere M., Malik M., Shibata T., et al. The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice. J Biol Chem 2010 Apr 16, 285(16):12344-12354.
    • (2010) J Biol Chem , vol.285 , Issue.16 , pp. 12344-12354
    • Mayers, C.M.1    Wadell, J.2    McLean, K.3    Venere, M.4    Malik, M.5    Shibata, T.6
  • 74
    • 34547166141 scopus 로고    scopus 로고
    • The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy
    • Appert-Collin A., Cotecchia S., Nenniger-Tosato M., Pedrazzini T., Diviani D. The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A 2007 Jun 12, 104(24):10140-10145.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.24 , pp. 10140-10145
    • Appert-Collin, A.1    Cotecchia, S.2    Nenniger-Tosato, M.3    Pedrazzini, T.4    Diviani, D.5
  • 75
    • 0026680801 scopus 로고
    • Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain
    • Carr D.W., Hausken Z.E., Fraser I.D., Stofko-Hahn R.E., Scott J.D. Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain. J Biol Chem 1992, 267(19):13376-13382.
    • (1992) J Biol Chem , vol.267 , Issue.19 , pp. 13376-13382
    • Carr, D.W.1    Hausken, Z.E.2    Fraser, I.D.3    Stofko-Hahn, R.E.4    Scott, J.D.5
  • 76
    • 0035941212 scopus 로고    scopus 로고
    • AKAP-Lbc anchors protein kinase A and nucleates galpha 12-selective Rho-mediated stress fiber formation
    • Diviani D., Soderling J., Scott J.D. AKAP-Lbc anchors protein kinase A and nucleates galpha 12-selective Rho-mediated stress fiber formation. J Biol Chem 2001 Nov 23, 276(47):44247-44257.
    • (2001) J Biol Chem , vol.276 , Issue.47 , pp. 44247-44257
    • Diviani, D.1    Soderling, J.2    Scott, J.D.3
  • 77
    • 17644370061 scopus 로고    scopus 로고
    • Leucine zipper-mediated homo-oligomerization regulates the Rho-GEF activity of AKAP-Lbc
    • Baisamy L., Jurisch N., Diviani D. Leucine zipper-mediated homo-oligomerization regulates the Rho-GEF activity of AKAP-Lbc. J Biol Chem 2005 Apr 15, 280(15):15405-15412.
    • (2005) J Biol Chem , vol.280 , Issue.15 , pp. 15405-15412
    • Baisamy, L.1    Jurisch, N.2    Diviani, D.3
  • 78
    • 79953141982 scopus 로고    scopus 로고
    • A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in alpha1-adrenergic receptor-induced p38 activation
    • Cariolato L., Cavin S., Diviani D. A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in alpha1-adrenergic receptor-induced p38 activation. J Biol Chem 2011 Mar 11, 286(10):7925-7937.
    • (2011) J Biol Chem , vol.286 , Issue.10 , pp. 7925-7937
    • Cariolato, L.1    Cavin, S.2    Diviani, D.3
  • 79
    • 4344598183 scopus 로고    scopus 로고
    • Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization
    • Jin J., Smith F.D., Stark C., Wells C.D., Fawcett J.P., Kulkarni S., et al. Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. Curr Biol 2004 Aug 24, 14(16):1436-1450.
    • (2004) Curr Biol , vol.14 , Issue.16 , pp. 1436-1450
    • Jin, J.1    Smith, F.D.2    Stark, C.3    Wells, C.D.4    Fawcett, J.P.5    Kulkarni, S.6
  • 80
    • 3543020962 scopus 로고    scopus 로고
    • Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex
    • Diviani D., Abuin L., Cotecchia S., Pansier L. Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex. EMBO J 2004 Jul 21, 23(14):2811-2820.
    • (2004) EMBO J , vol.23 , Issue.14 , pp. 2811-2820
    • Diviani, D.1    Abuin, L.2    Cotecchia, S.3    Pansier, L.4
  • 84
    • 79251617662 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinases 1 and 2 regulate the balance between eccentric and concentric cardiac growth
    • Kehat I., Davis J., Tiburcy M., Accornero F., Saba-El-Leil M.K., Maillet M., et al. Extracellular signal-regulated kinases 1 and 2 regulate the balance between eccentric and concentric cardiac growth. Circ Res 2011 Jan 21, 108(2):176-183.
    • (2011) Circ Res , vol.108 , Issue.2 , pp. 176-183
    • Kehat, I.1    Davis, J.2    Tiburcy, M.3    Accornero, F.4    Saba-El-Leil, M.K.5    Maillet, M.6
  • 85
    • 0036073345 scopus 로고    scopus 로고
    • Contributions of protein kinase A anchoring proteins to compartmentation of cAMP signaling in the heart
    • Kapiloff M.S. Contributions of protein kinase A anchoring proteins to compartmentation of cAMP signaling in the heart. Mol Pharmacol 2002 Aug, 62(2):193-199.
    • (2002) Mol Pharmacol , vol.62 , Issue.2 , pp. 193-199
    • Kapiloff, M.S.1
  • 87
    • 0035901502 scopus 로고    scopus 로고
    • MAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module
    • Dodge K.L., Khouangsathiene S., Kapiloff M.S., Mouton R., Hill E.V., Houslay M.D., et al. mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module. EMBO J 2001 Apr 17, 20(8):1921-1930.
    • (2001) EMBO J , vol.20 , Issue.8 , pp. 1921-1930
    • Dodge, K.L.1    Khouangsathiene, S.2    Kapiloff, M.S.3    Mouton, R.4    Hill, E.V.5    Houslay, M.D.6
  • 88
    • 0032842848 scopus 로고    scopus 로고
    • MAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes
    • Kapiloff M.S., Schillace R.V., Westphal A.M., Scott J.D. mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes. J Cell Sci 1999 Aug, 112(Pt. 16):2725-2736.
    • (1999) J Cell Sci , vol.112 , Issue.PART 16 , pp. 2725-2736
    • Kapiloff, M.S.1    Schillace, R.V.2    Westphal, A.M.3    Scott, J.D.4
  • 89
    • 30544452653 scopus 로고    scopus 로고
    • The mAKAP complex participates in the induction of cardiac myocyte hypertrophy by adrenergic receptor signaling
    • Pare G.C., Bauman A.L., McHenry M., Michel J.J., Dodge-Kafka K.L., Kapiloff M.S. The mAKAP complex participates in the induction of cardiac myocyte hypertrophy by adrenergic receptor signaling. J Cell Sci 2005 Dec 1, 118(Pt. 23):5637-5646.
    • (2005) J Cell Sci , vol.118 , Issue.PART 23 , pp. 5637-5646
    • Pare, G.C.1    Bauman, A.L.2    McHenry, M.3    Michel, J.J.4    Dodge-Kafka, K.L.5    Kapiloff, M.S.6
  • 90
    • 0034640113 scopus 로고    scopus 로고
    • PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts
    • Marx S.O., Reiken S., Hisamatsu Y., Jayaraman T., Burkhoff D., Rosemblit N., et al. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 2000 May 12, 101(4):365-376.
    • (2000) Cell , pp. 365-376
    • Marx, S.O.1    Reiken, S.2    Hisamatsu, Y.3    Jayaraman, T.4    Burkhoff, D.5    Rosemblit, N.6
  • 91
    • 0034789448 scopus 로고    scopus 로고
    • MAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope
    • Kapiloff M.S., Jackson N., Airhart N. mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope. J Cell Sci 2001 Sep, 114(Pt 17):3167-3176.
    • (2001) J Cell Sci , vol.114 , Issue.PART 17 , pp. 3167-3176
    • Kapiloff, M.S.1    Jackson, N.2    Airhart, N.3
  • 93
    • 74149093368 scopus 로고    scopus 로고
    • The mAKAPbeta scaffold regulates cardiac myocyte hypertrophy via recruitment of activated calcineurin
    • Li J., Negro A., Lopez J., Bauman A.L., Henson E., Dodge-Kafka K., et al. The mAKAPbeta scaffold regulates cardiac myocyte hypertrophy via recruitment of activated calcineurin. J Mol Cell Cardiol 2010 Feb, 48(2):387-394.
    • (2010) J Mol Cell Cardiol , vol.48 , Issue.2 , pp. 387-394
    • Li, J.1    Negro, A.2    Lopez, J.3    Bauman, A.L.4    Henson, E.5    Dodge-Kafka, K.6
  • 95
    • 36849051314 scopus 로고    scopus 로고
    • Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes
    • Faul C., Dhume A., Schecter A.D., Mundel P. Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes. Mol Cell Biol 2007 Dec, 27(23):8215-8227.
    • (2007) Mol Cell Biol , vol.27 , Issue.23 , pp. 8215-8227
    • Faul, C.1    Dhume, A.2    Schecter, A.D.3    Mundel, P.4
  • 96
    • 0042206722 scopus 로고    scopus 로고
    • Sodium/calcium exchanger (NCX1) macromolecular complex
    • Schulze D.H., Muqhal M., Lederer W.J., Ruknudin A.M. Sodium/calcium exchanger (NCX1) macromolecular complex. J Biol Chem 2003 Aug 1, 278(31):28849-28855.
    • (2003) J Biol Chem , vol.278 , Issue.31 , pp. 28849-28855
    • Schulze, D.H.1    Muqhal, M.2    Lederer, W.J.3    Ruknudin, A.M.4
  • 97
    • 0030006920 scopus 로고    scopus 로고
    • Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation
    • Sette C., Conti M. Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation. J Biol Chem 1996 Jul 12, 271(28):16526-16534.
    • (1996) J Biol Chem , vol.271 , Issue.28 , pp. 16526-16534
    • Sette, C.1    Conti, M.2
  • 98
    • 77951245640 scopus 로고    scopus 로고
    • CAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3
    • Dodge-Kafka K.L., Bauman A., Mayer N., Henson E., Heredia L., Ahn J., et al. cAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3. J Biol Chem 2010 Apr 9, 285(15):11078-11086.
    • (2010) J Biol Chem , vol.285 , Issue.15 , pp. 11078-11086
    • Dodge-Kafka, K.L.1    Bauman, A.2    Mayer, N.3    Henson, E.4    Heredia, L.5    Ahn, J.6
  • 99
    • 68749118345 scopus 로고    scopus 로고
    • Defining network topologies that can achieve biochemical adaptation
    • Ma W., Trusina A., El-Samad H., Lim W.A., Tang C. Defining network topologies that can achieve biochemical adaptation. Cell 2009 Aug 21, 138(4):760-773.
    • (2009) Cell , vol.138 , Issue.4 , pp. 760-773
    • Ma, W.1    Trusina, A.2    El-Samad, H.3    Lim, W.A.4    Tang, C.5
  • 100
    • 12344259872 scopus 로고    scopus 로고
    • Nesprin-1alpha contributes to the targeting of mAKAP to the cardiac myocyte nuclear envelope
    • Pare G.C., Easlick J.L., Mislow J.M., McNally E.M., Kapiloff M.S. Nesprin-1alpha contributes to the targeting of mAKAP to the cardiac myocyte nuclear envelope. Exp Cell Res 2005 Feb 15, 303(2):388-399.
    • (2005) Exp Cell Res , vol.303 , Issue.2 , pp. 388-399
    • Pare, G.C.1    Easlick, J.L.2    Mislow, J.M.3    McNally, E.M.4    Kapiloff, M.S.5
  • 101
    • 0036837672 scopus 로고    scopus 로고
    • Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth
    • Wilkins B.J., De Windt L.J., Bueno O.F., Braz J.C., Glascock B.J., Kimball T.F., et al. Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth. Mol Cell Biol 2002 Nov, 22(21):7603-7613.
    • (2002) Mol Cell Biol , vol.22 , Issue.21 , pp. 7603-7613
    • Wilkins, B.J.1    De Windt, L.J.2    Bueno, O.F.3    Braz, J.C.4    Glascock, B.J.5    Kimball, T.F.6
  • 104
    • 34447528668 scopus 로고    scopus 로고
    • Type 5 adenylyl cyclase disruption increases longevity and protects against stress
    • Yan L., Vatner D.E., O'Connor J.P., Ivessa A., Ge H., Chen W., et al. Type 5 adenylyl cyclase disruption increases longevity and protects against stress. Cell 2007 Jul 27, 130(2):247-258.
    • (2007) Cell , vol.130 , Issue.2 , pp. 247-258
    • Yan, L.1    Vatner, D.E.2    O'Connor, J.P.3    Ivessa, A.4    Ge, H.5    Chen, W.6
  • 106
    • 26244467287 scopus 로고    scopus 로고
    • Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias
    • Lehnart S.E., Wehrens X.H., Reiken S., Warrier S., Belevych A.E., Harvey R.D., et al. Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias. Cell 2005 Oct 7, 123(1):25-35.
    • (2005) Cell , vol.123 , Issue.1 , pp. 25-35
    • Lehnart, S.E.1    Wehrens, X.H.2    Reiken, S.3    Warrier, S.4    Belevych, A.E.5    Harvey, R.D.6
  • 109
    • 0035355360 scopus 로고    scopus 로고
    • Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy
    • Nicol R.L., Frey N., Pearson G., Cobb M., Richardson J., Olson E.N. Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy. EMBO J 2001 Jun 1, 20(11):2757-2767.
    • (2001) EMBO J , vol.20 , Issue.11 , pp. 2757-2767
    • Nicol, R.L.1    Frey, N.2    Pearson, G.3    Cobb, M.4    Richardson, J.5    Olson, E.N.6


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