Mutation of an A-kinase-anchoring protein causes long-QT syndrome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 52, 2007, Pages 20990-20995

  Chen, Lei ^a   Marquardt, Michelle L ^b   Tester, David J ^b   Sampson, Kevin J ^a   Ackerman, Michael J ^b   Kass, Robert S ^a  

^a Columbia University ^*  (United States)

^b Mayo Clinic   (United States)

Author keywords

Potassium channel; Protein kinase A

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; POTASSIUM CHANNEL KCNQ1;

ACTION POTENTIAL; ADOLESCENT; ADULT; AGED; ANIMAL CELL; ARTICLE; CHILD; CLINICAL ARTICLE; FEMALE; GENE MUTATION; HEART REPOLARIZATION; HUMAN; LONG QT SYNDROME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

A KINASE ANCHOR PROTEINS; ADOLESCENT; ADULT; AGED; BINDING SITES; CHILD; CHILD, PRESCHOOL; CYTOSKELETAL PROTEINS; DNA MUTATIONAL ANALYSIS; FEMALE; HUMANS; INFANT; KCNQ1 POTASSIUM CHANNEL; LONG QT SYNDROME; MALE; MIDDLE AGED; MUTATION; POTASSIUM CHANNELS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ADRENERGIC, BETA;

EID: 38049169040     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0710527105     Document Type: Article

References (24)

1. McConnachie G, Langeberg LK, Scott JD (2006) Trends Mol Med 12:317-323.
2. Dodge-Kafka KL, Langeberg L, Scott JD (2006) Circ Res 98:993-1001.
3. Smith FD, Langeberg LK, Scott JD (2006) Trends Biochem Sci 31:316-323.
4. Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR (2000) Cell 101:365-376.
5. Hulme JT, Westenbroek RE, Scheuer T, Catterall WA (2006) Proc Natl Acad Sci USA 103:16574-16579.
6. Hulme JT, Lin TW, Westenbroek RE, Scheuer T, Catterall WA (2003) Proc Natl Acad Sci USA 100:13093-13098.
7. Marx SO, Kurokawa J, Reiken S, Motoike H, D'Armiento J, Marks AR, Kass RS (2002) Science 295:496-499.
8. Lehnart SE, Wehrens XH, Laitinen PJ, Reiken SR, Deng SX, Cheng Z, Landry DW, Kontula K, Swan H, Marks AR (2004) Circulation 109:3208-3214.
9. Moss AJ, Kass RS (2005) J Clin Invest 115:2018-2024.
10. Wang Q, Curran ME, Splawski I, Burn TC, Millholland JM, VanRaay TJ, Shen J, Timothy KW, Vincent GM, de Jager T, et al. (1996) Nat Genet 12:17-23.
11. Abbott GW, Goldstein SA (2002) FASEB J 16:390-400.
12. Terrenoire C, Clancy CE, Cormier JW, Sampson KJ, Kass RS (2005) Circ Res 96:e25-34.
13. Schwartz PJ, Priori SG, Spazzolini C, Moss AJ, Vincent GM, Napolitano C, Denjoy I, Guicheney P, Breithardt G, Keating MT, et al. (2001) Circulation 103:89-95.
14. Piippo K, Swan H, Pasternack M, Chapman H, Paavonen K, Viitasalo M, Toivonen L, Kontula K (2001) J Am Coll Cardiol 37:562-568.
15. Kurokawa J, Chen L, Kass RS (2003) Proc Natl Acad Sci USA 100:2122-2127.
16. ten Tusscher KH, Noble D, Noble PJ, Panfilov AV (2004) Am J Physiol Heart Circ Physiol 286:H1573-1589.
17. Chen L, Kurokawa J, Kass RS (2005) J Biol Chem 280:31347-31352.
18. Kurokawa J, Motoike HK, Rao J, Kass RS (2004) Proc Natl Acad Sci USA 101:16374-16378.
19. Tester DJ, Will ML, Haglund CM, Ackerman MJ (2005) Heart Rhythm 2:507-517.
20. Sherman J, Tester DJ, Ackerman MJ (2005) Heart Rhythm 2:1218-1223.
21. Vatta M, Ackerman MJ, Ye B, Makielski JC, Ughanze EE, Taylor EW, Tester DJ, Balijepalli RC, Foell JD, Li Z, et al. (2006) Circulation 114:2104-2112.
22. Schwartz PJ, Moss AJ, Vincent GM, Crampton RS (1993) Circulation 88:782-784.
23. Carlisle Michel JJ, Dodge KL, Wong W, Mayer NC, Langeberg LK, Scott JD (2004) Biochem J 381:587-592.
24. Dodge KL, Khouangsathiene S, Kapiloff MS, Mouton R, Hill EV, Houslay MD, Langeberg LK, Scott JD (2001) EMBO J 20:1921-1930.