Adenylyl Cyclase 6 Deletion Reduces Left Ventricular Hypertrophy, Dilation, Dysfunction, and Fibrosis in Pressure-Overloaded Female Mice

Journal of the American College of Cardiology

Volumn 55, Issue 14, 2010, Pages 1476-1486

  Tang, Tong ^a,b   Lai, N Chin ^a,b   Hammond, H Kirk ^a,b   Roth, David M ^a,c   Yang, Yuan ^b   Guo, Tracy ^b   Gao, Mei Hua ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c University of California   (United States)

Author keywords

heart failure; left ventricular function; left ventricular remodeling; transgenic animal models

Indexed keywords

ADENYLATE CYCLASE; ADENYLATE CYCLASE 6; ALPHA ACTIN; ALPHA SKELETAL MUSCLE ACTIN; ATRIAL NATRIURETIC FACTOR; COLLAGEN TYPE 1; MYOSIN HEAVY CHAIN BETA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FHL1; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CONSTRICTION; ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; FEMALE; FIBROBLAST; GENE DELETION; GENE EXPRESSION; HEART DILATATION; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE FIBROSIS; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE OUTFLOW TRACT; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TIBIA SHAFT; TRANVERSE AORTIC CONSTRICTION;

ADENYLATE CYCLASE; ANIMALS; CELL ADHESION MOLECULES; FEMALE; HYPERTROPHY, LEFT VENTRICULAR; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUSCLE PROTEINS; SEQUENCE DELETION; VENTRICULAR DYSFUNCTION, LEFT;

EID: 77949908921     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2009.11.066     Document Type: Article

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