Sulfur and selenium derivatives of quinazoline and pyrido[2,3-d]pyrimidine: Synthesis and study of their potential cytotoxic activity in vitro

European Journal of Medicinal Chemistry

Volumn 47, Issue 1, 2012, Pages 283-298

  Moreno, Esther ^a   Plano, Daniel ^a   Lamberto, Iranzu ^a   Font, María ^a   Encío, Ignacio ^b   Palop, Juan Antonio ^a   Sanmartín, Carmen ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b PUBLIC UNIVERSITY OF NAVARRE   (Spain)

Author keywords

Antiproliferatives; Cytotoxics; Pyridopyrimidines; Quinazolines

Indexed keywords

2 METHYLTHIO 4 (2 PHENYLETHYL)AMINOQUINAZOLINE; 2 METHYLTHIO 4 (3 PHENYLPROPYL)AMINOQUINAZOLINE; 2 METHYLTHIO 4 (4 PHENYLBUTYL)AMINOQUINAZOLINE; 2 METHYLTHIO 4 (4' METHYLSELENOBENZYL)AMINOQUINAZOLINE; 2 METHYLTHIO 4 PHENYLQUINAZOLINE; 2 PENTYLTHIO 4 (4' METHYLSELENOBENZYL)AMINOQUINAZOLINE; 2,4 DIHYDROSELENOPYRIDO[2,3 D]PYRIMIDINE; 2,4 DIHYDROSELENOQUINAZOLINE; 2,4 DIMETHYLSELENOPYRIDO[2,3 D]PYRIMIDINE; 2,4 DIMETHYLSELENOQUINAZOLINE; 2,4 DIPENTYLSELENOPYRIDO[2,3 D]PYRIMIDINE; 2,4 DIPENTYLSELENOQUINAZOLINE; 4 (4' METHOXYBENZYL)AMINO 2 METHYLTHIOPYRIDO[2,3 D]PYRIMIDINE; 4 (4' METHOXYBENZYL)AMINO 2 METHYLTHIOQUINAZOLINE; 4 (4' METHYLTHIOBENZYL)AMINO 2 METHYLTHIOPYRIDO[2,3 D]PYRIMIDINE; 4 (4' METHYLTHIOBENZYL)AMINO 2 METHYLTHIOQUINAZOLINE; 4 (5 HYDROXYPENTYL)AMINO 2 METHYLTHIOPYRIDO[2,3 D]PYRIMIDINE; 4 (5 HYDROXYPENTYL)AMINO 2 METHYLTHIOQUINAZOLINE; 4 AMINO 2 HYDROSELENOPYRIDO[2,3 D]PYRIMIDINE; 4 AMINO 2 HYDROSELENOQUINAZOLINE; 4 BENZYLAMINO 2 MERCAPTO QUINAZOLINE; 4 BENZYLAMINO 2 METHYLTHIOPYRIDO[2,3 D]PYRIMIDINE; 4 BENZYLAMINO 2 METHYLTHIOQUINAZOLINE; ANTINEOPLASTIC AGENT; MERCAPTO 4 (4' METHOXYBENZYL)AMINOQUINAZOLINE; PYRIDO[2,3 D]PYRIMIDINE DERIVATIVE; QUINAZOLINE DERIVATIVE; SELENIUM DERIVATIVE; SULFUR DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL CYCLE PHASE; CELL CYCLE PROGRESSION; CELL DEATH; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; PHYSICAL CHEMISTRY;

ABSORPTION; ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL DEATH; CELL LINE, TUMOR; HUMANS; PYRIMIDINES; QUINAZOLINES; SELENIUM; SULFUR;

EID: 84855819783     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.10.056     Document Type: Article

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