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Volumn 89, Issue 25-26, 2011, Pages 939-945

Quercetin and rutin exhibit antiamyloidogenic and fibril-disaggregating effects in vitro and potent antioxidant activity in APPswe cells

Author keywords

Antiamyloidogenic; APPswe; Glutathione; Lipid peroxidation; Quercetin; Rutin

Indexed keywords

AMYLOID BETA PROTEIN[25-35]; GLUTATHIONE; QUERCETIN; REACTIVE OXYGEN METABOLITE; RUTOSIDE; AMYLOID; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (25 35); AMYLOID BETA-PROTEIN (25-35); ANTIOXIDANT; HYDROGEN PEROXIDE; PEPTIDE FRAGMENT; SECRETASE;

EID: 84855730408     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.09.023     Document Type: Article
Times cited : (207)

References (44)
  • 1
    • 77957019415 scopus 로고    scopus 로고
    • Amyloid precursor protein gene mutated at Swedish 670/671 sites in vitro induces changed expression of nicotinic acetylcholine receptors and neurotoxicity
    • An Y, Qi XL, Pei JJ, Tang Z, Xiao Y, Guan ZZ. Amyloid precursor protein gene mutated at Swedish 670/671 sites in vitro induces changed expression of nicotinic acetylcholine receptors and neurotoxicity. Neurochem Int 2010;57(6):647-54.
    • (2010) Neurochem Int , vol.57 , Issue.6 , pp. 647-654
    • An, Y.1    Qi, X.L.2    Pei, J.J.3    Tang, Z.4    Xiao, Y.5    Guan, Z.Z.6
  • 2
    • 0033972299 scopus 로고    scopus 로고
    • Modulation of liposomal membrane fluidity by flavonoids and isoflavonoids
    • Arora A, Byrem TM, Nair MG, Strasburg GM. Modulation of liposomal membrane fluidity by flavonoids and isoflavonoids. Arch Biochem Biophys 2000;373(1):102-9.
    • (2000) Arch Biochem Biophys , vol.373 , Issue.1 , pp. 102-109
    • Arora, A.1    Byrem, T.M.2    Nair, M.G.3    Strasburg, G.M.4
  • 3
    • 77955097118 scopus 로고    scopus 로고
    • After cellular internalization, quercetin causes Nrf2 nuclear translocation, increases glutathione levels, and prevents neuronal death against an oxidative insult
    • Arredondo F, Echeverry C, Abin-Carriquiry JA, Blasina F, Antunez K, Jones DP, et al. After cellular internalization, quercetin causes Nrf2 nuclear translocation, increases glutathione levels, and prevents neuronal death against an oxidative insult. Free Radic Biol Med 2010;49(5):738-47.
    • (2010) Free Radic Biol Med , vol.49 , Issue.5 , pp. 738-747
    • Arredondo, F.1    Echeverry, C.2    Abin-Carriquiry, J.A.3    Blasina, F.4    Antunez, K.5    Jones, D.P.6
  • 4
    • 45549095784 scopus 로고    scopus 로고
    • Polyphenols as potential inhibitors of amyloid aggregation and toxicity: Possible significance to Alzheimer's disease
    • Bastianetto S, Krantic S, Quirion R. Polyphenols as potential inhibitors of amyloid aggregation and toxicity: possible significance to Alzheimer's disease. Mini Rev Med Chem 2008;8(5):429-35.
    • (2008) Mini Rev Med Chem , vol.8 , Issue.5 , pp. 429-435
    • Bastianetto, S.1    Krantic, S.2    Quirion, R.3
  • 5
    • 39749157595 scopus 로고    scopus 로고
    • Peripheral levels of glutathione and protein oxidation as markers in the development of Alzheimer's disease from mild cognitive impairment
    • Bermejo P, Martin-Aragon S, Benedi J, Susin C, Felici E, Gil P, et al. Peripheral levels of glutathione and protein oxidation as markers in the development of Alzheimer's disease from mild cognitive impairment Free Radic Res 2008;42(2):162-70.
    • (2008) Free Radic Res , vol.42 , Issue.2 , pp. 162-170
    • Bermejo, P.1    Martin-Aragon, S.2    Benedi, J.3    Susin, C.4    Felici, E.5    Gil, P.6
  • 8
    • 47549118915 scopus 로고    scopus 로고
    • Quercetin and rutin as potential sunscreen agents: Determination of efficacy by an in vitro method
    • Choquenet B, Couteau Cl, Paparis E, Coiffard LJM. Quercetin and rutin as potential sunscreen agents: determination of efficacy by an in vitro method. J Nat Prod 2008;71 (6):1117-8.
    • (2008) J Nat Prod , vol.71 , Issue.6 , pp. 1117-1118
    • Choquenet, B.1    Cl, C.2    Paparis, E.3    Coiffard, L.J.M.4
  • 11
    • 0035871971 scopus 로고    scopus 로고
    • Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation
    • Eckert A, Steiner B, Marques C, Leutz S, Romig H, Haass C, et al. Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation. J Neurosci Res 2001;64(2):183-92.
    • (2001) J Neurosci Res , vol.64 , Issue.2 , pp. 183-192
    • Eckert, A.1    Steiner, B.2    Marques, C.3    Leutz, S.4    Romig, H.5    Haass, C.6
  • 13
    • 33745052352 scopus 로고    scopus 로고
    • Development of BACE1 inhibitors for Alzheimer's disease
    • Guo T, Hobbs DW. Development of BACE1 inhibitors for Alzheimer's disease. Curr Med Chem 2006;13(15):1811-29.
    • (2006) Curr Med Chem , vol.13 , Issue.15 , pp. 1811-1829
    • Guo, T.1    Hobbs, D.W.2
  • 14
    • 1442264828 scopus 로고    scopus 로고
    • Take five-BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation
    • Haass C. Take five-BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation. EMBO J 2004;23(3):483-8.
    • (2004) EMBO J , vol.23 , Issue.3 , pp. 483-488
    • Haass, C.1
  • 15
    • 3042559829 scopus 로고    scopus 로고
    • Potent inhibitory effect of flavonoids in Scutellaria baicalensis on amyloid beta protein-induced neurotoxicity
    • Heo HJ, Kim DO, Choi SJ, Shin DH, Lee CY Potent inhibitory effect of flavonoids in Scutellaria baicalensis on amyloid beta protein-induced neurotoxicity. J Agric Food Chem 2004;52 (13):4128-32.
    • (2004) J Agric Food Chem , vol.52 , Issue.13 , pp. 4128-4132
    • Heo, H.J.1    Kim, D.O.2    Choi, S.J.3    Shin, D.H.4    Lee, C.Y.5
  • 17
    • 48749116996 scopus 로고    scopus 로고
    • Appraisal of casein's inhibitory effects on aggregation accompanying carbonic anhydrase refolding and heat-induced ovalbumin fibrillogenesis
    • Khodarahmi R, Beyrami M, Soori H. Appraisal of casein's inhibitory effects on aggregation accompanying carbonic anhydrase refolding and heat-induced ovalbumin fibrillogenesis. Arch Biochem Biophys 2008;477(1):67-76.
    • (2008) Arch Biochem Biophys , vol.477 , Issue.1 , pp. 67-76
    • Khodarahmi, R.1    Beyrami, M.2    Soori, H.3
  • 18
    • 0035957946 scopus 로고    scopus 로고
    • Alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity
    • Kihara T, Shimohama S, Sawada H, Honda K, Nakamizo T, Shibasaki H, et al. alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity. J Biol Chem 2001;276(17):13541-6.
    • (2001) J Biol Chem , vol.276 , Issue.17 , pp. 13541-13546
    • Kihara, T.1    Shimohama, S.2    Sawada, H.3    Honda, K.4    Nakamizo, T.5    Shibasaki, H.6
  • 19
    • 4644372714 scopus 로고    scopus 로고
    • Comprehensive study on vitamin C equivalent antioxidant capacity (VCEAC) of various polyphenolics in scavenging a free radical and its structural relationship
    • Kim DO, Lee CY. Comprehensive study on vitamin C equivalent antioxidant capacity (VCEAC) of various polyphenolics in scavenging a free radical and its structural relationship. Crit Rev Food Sci Nutr 2004;44(4):253-73.
    • (2004) Crit Rev Food Sci Nutr , vol.44 , Issue.4 , pp. 253-273
    • Kim, D.O.1    Lee, C.Y.2
  • 20
    • 27744563958 scopus 로고    scopus 로고
    • Effects of naturally occurring compounds on fibril formation and oxidative stress of beta-amyloid
    • Kim H, Park BS, Lee KG, Choi CY, Jang SS, Kim YH, et al. Effects of naturally occurring compounds on fibril formation and oxidative stress of beta-amyloid. J Agric Food Chem 2005;53(22):8537-41.
    • (2005) J Agric Food Chem , vol.53 , Issue.22 , pp. 8537-8541
    • Kim, H.1    Park, B.S.2    Lee, K.G.3    Choi, C.Y.4    Jang, S.S.5    Kim, Y.H.6
  • 21
    • 19444375717 scopus 로고    scopus 로고
    • Evidence for intact selective attention in Alzheimer's disease patients using a location priming task
    • Ko PC, Kilduff PT, Higgens JA, Milberg W, McGlinchey R. Evidence for intact selective attention in Alzheimer's disease patients using a location priming task. Neuropsychology 2005;19(3):381-9.
    • (2005) Neuropsychology , vol.19 , Issue.3 , pp. 381-389
    • Ko, P.C.1    Kilduff, P.T.2    Higgens, J.A.3    Milberg, W.4    McGlinchey, R.5
  • 22
    • 0035826909 scopus 로고    scopus 로고
    • Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha-secretase ADAM 10
    • Kojro E, Gimpl G, Lammich S, Marz W, Fahrenholz F. Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha-secretase ADAM 10. Proc Natl Acad Sci U S A 2001;98(10):5815-20.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.10 , pp. 5815-5820
    • Kojro, E.1    Gimpl, G.2    Lammich, S.3    Marz, W.4    Fahrenholz, F.5
  • 23
    • 0026554428 scopus 로고
    • Evaluation of the probe 2′, 7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress
    • LeBel CP, Ischiropoulos H, Bondy SC. Evaluation of the probe 2′, 7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem Res Toxicol 1992;5(2):227-31.
    • (1992) Chem Res Toxicol , vol.5 , Issue.2 , pp. 227-231
    • Lebel, C.P.1    Ischiropoulos, H.2    Bondy, S.C.3
  • 24
    • 3242686012 scopus 로고    scopus 로고
    • Glutathione metabolism during aging and in Alzheimer disease
    • Liu H, Wang H, Shenvi S, Hagen TM, Liu RM. Glutathione metabolism during aging and in Alzheimer disease. Ann N Y Acad Sci 2004;1019:346-9.
    • (2004) Ann N y Acad Sci , vol.1019 , pp. 346-349
    • Liu, H.1    Wang, H.2    Shenvi, S.3    Hagen, T.M.4    Liu, R.M.5
  • 25
    • 33846922600 scopus 로고    scopus 로고
    • Gamma-secretase: A complex target for Alzheimer's disease
    • Lundkvist J, Naslund J. Gamma-secretase: a complex target for Alzheimer's disease. Curr Opin Pharmacol 2007;7(1):112-8.
    • (2007) Curr Opin Pharmacol , vol.7 , Issue.1 , pp. 112-118
    • Lundkvist, J.1    Naslund, J.2
  • 26
    • 0042847291 scopus 로고    scopus 로고
    • Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: Oxidative stress, caspases, and the JNK pathway
    • Marques CA, Keil U, Bonert A, Steiner B, Haass C, Muller WE, et al. Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway. J Biol Chem 2003;278(30):28294-302.
    • (2003) J Biol Chem , vol.278 , Issue.30 , pp. 28294-28302
    • Marques, C.A.1    Keil, U.2    Bonert, A.3    Steiner, B.4    Haass, C.5    Muller, W.E.6
  • 27
    • 0034643895 scopus 로고    scopus 로고
    • Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells
    • Misonou H, Morishima-Kawashima M, Ihara Y. Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells. Biochemistry 2000;39(23):6951-9.
    • (2000) Biochemistry , vol.39 , Issue.23 , pp. 6951-6959
    • Misonou, H.1    Morishima-Kawashima, M.2    Ihara, Y.3
  • 28
    • 84984560798 scopus 로고    scopus 로고
    • Attachment of rhamnosyl glucoside on quercetin confers potent iron-chelating ability on its antioxidant properties
    • Omololu PA, Rocha JBT, Kade IJ. Attachment of rhamnosyl glucoside on quercetin confers potent iron-chelating ability on its antioxidant properties. Exp Toxicol Pathol 2011;63(3):249-55.
    • (2011) Exp Toxicol Pathol , vol.63 , Issue.3 , pp. 249-255
    • Omololu, P.A.1    Rocha, J.B.T.2    Kade, I.J.3
  • 29
    • 33745173188 scopus 로고    scopus 로고
    • Anti-amyloidogenic effects of antioxidants: Implications for the prevention and therapeutics of Alzheimer's disease
    • Ono K, Hamaguchi T, Naiki H, Yamada M. Anti-amyloidogenic effects of antioxidants: implications for the prevention and therapeutics of Alzheimer's disease. Biochim Biophys Acta 2006;1762(6):575-86.
    • (2006) Biochim Biophys Acta , vol.1762 , Issue.6 , pp. 575-586
    • Ono, K.1    Hamaguchi, T.2    Naiki, H.3    Yamada, M.4
  • 30
    • 0028981219 scopus 로고
    • Structure-activity analyses of beta-amyloid peptides: Contributions of the beta 25-35 region to aggregation and neurotoxicity
    • Pike CJ, Walencewicz-Wasserman AJ, Kosmoski J, Cribbs DH, Glabe CG, Cotman CW. Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity. J Neurochem 1995;64(1):253-65.
    • (1995) J Neurochem , vol.64 , Issue.1 , pp. 253-265
    • Pike, C.J.1    Walencewicz-Wasserman, A.J.2    Kosmoski, J.3    Cribbs, D.H.4    Glabe, C.G.5    Cotman, C.W.6
  • 31
    • 8544272519 scopus 로고    scopus 로고
    • Inhibition of islet amyloid polypeptide fibril formation: A potential role for heteroaromatic interactions
    • Porat Y, Mazor Y, Efrat S, Gazit E. Inhibition of islet amyloid polypeptide fibril formation: a potential role for heteroaromatic interactions. Biochemistry 2004;43(45):14454-62.
    • (2004) Biochemistry , vol.43 , Issue.45 , pp. 14454-14462
    • Porat, Y.1    Mazor, Y.2    Efrat, S.3    Gazit, E.4
  • 34
    • 17344388652 scopus 로고    scopus 로고
    • BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: Implications for Alzheimer's disease therapeutics
    • Roberds SL, Anderson J, Basi G, Bienkowski MJ, Branstetter DG, Chen KS, et al. BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics. Hum Mol Genet 2001;10 (12):1317-24.
    • (2001) Hum Mol Genet , vol.10 , Issue.12 , pp. 1317-1324
    • Roberds, S.L.1    Anderson, J.2    Basi, G.3    Bienkowski, M.J.4    Branstetter, D.G.5    Chen, K.S.6
  • 36
    • 0034630183 scopus 로고    scopus 로고
    • Determining glutathione and glutathione disulfide using the fluorescence probe o-phthalaldehyde
    • Senft AP, Dalton TP, Shertzer HG. Determining glutathione and glutathione disulfide using the fluorescence probe o-phthalaldehyde. Anal Biochem 2000;280(1):80-6.
    • (2000) Anal Biochem , vol.280 , Issue.1 , pp. 80-86
    • Senft, A.P.1    Dalton, T.P.2    Shertzer, H.G.3
  • 37
    • 45049086920 scopus 로고    scopus 로고
    • Flavonols and flavonesas BACE-1 inhibitors: Structure-activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features
    • Shimmyo Y, Kihara T, Akaike A, Niidome T, Sugimoto H.Flavonols and flavonesas BACE-1 inhibitors: structure-activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features. Biochim Biophys Acta (BBA)-Gen Subj 2008;1780(5):819-25.
    • (2008) Biochim Biophys Acta (BBA)-Gen Subj , vol.1780 , Issue.5 , pp. 819-825
    • Shimmyo, Y.1    Kihara, T.2    Akaike, A.3    Niidome, T.4    Sugimoto, H.5
  • 38
    • 56349138961 scopus 로고    scopus 로고
    • Quercetin and interferon-beta modulate immune response(s) in peripheral blood mononuclear cells isolated from multiple sclerosis patients
    • Sternberg Z, Chadha K, Lieberman A, Hojnacki D, Drake A, Zamboni P, et al. Quercetin and interferon-beta modulate immune response(s) in peripheral blood mononuclear cells isolated from multiple sclerosis patients. J Neuroimmunol 2008;205(1-2):142-7.
    • (2008) J Neuroimmunol , vol.205 , Issue.1-2 , pp. 142-147
    • Sternberg, Z.1    Chadha, K.2    Lieberman, A.3    Hojnacki, D.4    Drake, A.5    Zamboni, P.6
  • 39
    • 33845505233 scopus 로고    scopus 로고
    • Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression
    • Sun X, He G, Qing H, Zhou W, Dobie F, Cai F, et al. Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression. Proc Natl Acad Sci U S A 2006;103(49):18727-32.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.49 , pp. 18727-18732
    • Sun, X.1    He, G.2    Qing, H.3    Zhou, W.4    Dobie, F.5    Cai, F.6
  • 40
    • 46149138568 scopus 로고
    • Antioxidant activity of flavonoids and reactivity with peroxy radical
    • Torel J, Cillard J, Cillard P. Antioxidant activity of flavonoids and reactivity with peroxy radical. Phytochemistry 1986;25(2):383-5.
    • (1986) Phytochemistry , vol.25 , Issue.2 , pp. 383-385
    • Torel, J.1    Cillard, J.2    Cillard, P.3
  • 42
    • 33745254486 scopus 로고    scopus 로고
    • Quercetin content in some food and herbal samples
    • Wach A, Pyrzynska K, Biesaga M. Quercetin content in some food and herbal samples. Food Chem 2007;100(2):699-704.
    • (2007) Food Chem , vol.100 , Issue.2 , pp. 699-704
    • Wach, A.1    Pyrzynska, K.2    Biesaga, M.3
  • 43
    • 4444226105 scopus 로고    scopus 로고
    • Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases
    • Weinreb O, Mandel S, Amit T, Youdim MBH. Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases. J Nutr Biochem 2004;15(9):506-16.
    • (2004) J Nutr Biochem , vol.15 , Issue.9 , pp. 506-516
    • Weinreb, O.1    Mandel, S.2    Amit, T.3    Youdim, M.B.H.4
  • 44
    • 78449300244 scopus 로고    scopus 로고
    • Thiamine deficiency increases beta-secretase activity and accumulation of beta-amyloid peptides
    • Zhang Q, Yang G, Li W, Fan Z, Sun A, Luo J, et al. Thiamine deficiency increases beta-secretase activity and accumulation of beta-amyloid peptides. Neurobiol Aging 2011;32(1): 42-53.
    • (2011) Neurobiol Aging , vol.32 , Issue.1 , pp. 42-53
    • Zhang, Q.1    Yang, G.2    Li, W.3    Fan, Z.4    Sun, A.5    Luo, J.6


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