Inhibition of islet amyloid polypeptide fibril formation: A potential role for heteroaromatic interactions

Biochemistry

Volumn 43, Issue 45, 2004, Pages 14454-14462

  Porat, Yair ^a   Mazor, Yariv ^a   Efrat, Shimon ^a   Gazit, Ehud ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC POLYMERS; BIOASSAY; DISEASES; HYDROPHOBICITY; PHENOLS; POLYPEPTIDES; SUBSTITUTION REACTIONS;

ALZHEIMER'S DISEASE; AMYLOID POLYPEPTIDE FIBRIL; DIABETES;

ENZYME INHIBITION;

AMYLOID; AROMATIC COMPOUND; BENZENE; PEPTIDE; PHENOL; PHENOLSULFONPHTHALEIN; PHENYLALANINE; THYROXINE;

ALZHEIMER DISEASE; ARTICLE; BETA SHEET; CYTOTOXICITY; HUMAN; HUMAN CELL; HYDROPHOBICITY; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PRION DISEASE; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION;

AMINO ACID SUBSTITUTION; AMYLOID; ANIMALS; CELL LINE; CELL SURVIVAL; DIABETES MELLITUS, TYPE 2; FLAVONOIDS; GROWTH INHIBITORS; HUMANS; ISLETS OF LANGERHANS; MICE; PC12 CELLS; PEPTIDE FRAGMENTS; PHENOLS; PHENOLSULFONPHTHALEIN; PHENYLALANINE; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; RATS; SPECTROMETRY, FLUORESCENCE; TYROSINE;

EID: 8544272519     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048582a     Document Type: Article

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