Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation

Journal of Neuroscience Research

Volumn 64, Issue 2, 2001, Pages 183-192

  Eckert, Anne ^a   Steiner, Barbara ^a   Marques, Celio ^a   Leutz, Steffen ^a   Romig, Helmut ^b   Haass, Christian ^c   Müller, Walter E ^a  

^a GOETHE UNIVERSITY   (Germany)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Alheimer's disease; Apoptosis; Hydorgen peroxide; Swedish mutation; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CASPASE 3; DNA FRAGMENT; HYDROGEN PEROXIDE; INTERLEUKIN 1BETA CONVERTING ENZYME; MUTANT PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN; CONTROLLED STUDY; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ALZHEIMER DISEASE; AMINO ACID CHLOROMETHYL KETONES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANILIDES; ANIMALS; ANTIOXIDANTS; APOPTOSIS; ASPARTIC ENDOPEPTIDASES; CASPASE 3; CASPASES; CYSTEINE PROTEINASE INHIBITORS; ENDOPEPTIDASES; ENZYME ACTIVATION; HUMANS; HYDROGEN PEROXIDE; MUTATION; NERVE TISSUE PROTEINS; OLIGOPEPTIDES; OXIDATIVE STRESS; PC12 CELLS; PEPTIDES; PROTEINS; RATS; SWEDEN; TRANSFECTION; VITAMIN E;

EID: 0035871971     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.1064     Document Type: Article

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