Stem cell gene therapy: The risks of insertional mutagenesis and approaches to minimize genotoxicity

Frontiers of Medicine in China

Volumn 5, Issue 4, 2011, Pages 356-371

  Wu, Chuanfeng ^a   Dunbar, Cynthia E ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

gene therapy; genotoxicity; hematopoietic stem cells; induced pluripotent stem cell; insertional mutagenesis

Indexed keywords

CYTOLOGY; GENE EXPRESSION REGULATION; GENE THERAPY; GENE VECTOR; HEMATOPOIETIC STEM CELL; HUMAN; METHODOLOGY; PLURIPOTENT STEM CELL; REVIEW; VIROLOGY;

GENE THERAPY; GENETIC VECTORS; HEMATOPOIETIC STEM CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MUTAGENESIS, INSERTIONAL;

EID: 84255196304     PISSN: 16737342     EISSN: 16737458     Source Type: Journal    
DOI: 10.1007/s11684-011-0159-1     Document Type: Review

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