Tlymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates

Nature Medicine

Volumn 4, Issue 7, 1998, Pages 775-780

  Kohn, Donald B ^a   Hershfield, Michael S ^b   Carbonaro, Denise ^a   Shigeoka, Ann ^c   Brooks, Judith ^a   Smogorzewska, E Monika ^a   Barsky, Lora W ^a   Chan, Raymond ^a   Burotto, Felix ^a   Annett, Geralyn ^a   Nolta, Jan A ^a   Crooks, Gay ^a   Kapoor, Neena ^a   Elder, Melissa ^d   Wara, Diane ^d   Bowen, Thomas ^e   Madsen, Edward ^e   Snyder, Floyd F ^f   Bastian, John ^g   Muul, Linda ^h   Blaese, R Michael ^h   Weinberg, Kenneth ^a   Parkman, Robertson ^a   more..

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b DUKE UNIVERSITY   (United States)

^c UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e #705 South Tower ^*  (United States)

^f ALBERTA CHILDREN'S HOSPITAL   (Canada)

^g RADY CHILDREN'S HOSPITAL   (United States)

^h NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; VIRUS VECTOR; ADENOSINE DEAMINASE; MACROGOL DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CELL TRANSPLANTATION; COMBINED IMMUNODEFICIENCY; ENZYME DEFICIENCY; GENE FREQUENCY; GENE THERAPY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; T LYMPHOCYTE; UMBILICAL CORD BLOOD; ANIMAL; AUTOTRANSPLANTATION; CELL LINE; DRUG EFFECT; FLOW CYTOMETRY; GENETIC TRANSFORMATION; GENETICS; GRANULOCYTE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY; IMMUNOLOGY; LYMPHOCYTE COUNT; METABOLISM; MONONUCLEAR CELL; MOUSE MUTANT; UMBILICAL CORD;

ANIMALIA; UNIDENTIFIED RETROVIRUS;

ADENOSINE DEAMINASE; ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD34; CELL LINE; FLOW CYTOMETRY; GENE FREQUENCY; GRANULOCYTES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE COUNT; MICE; MICE, SCID; POLYETHYLENE GLYCOLS; T-LYMPHOCYTES; TRANSFORMATION, GENETIC; TRANSPLANTATION IMMUNOLOGY; TRANSPLANTATION, AUTOLOGOUS; UMBILICAL CORD;

EID: 0031593688     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0798-775     Document Type: Article

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