메뉴 건너뛰기




Volumn 106, Issue 12, 2005, Pages 3932-3939

Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 3; STEM CELL FACTOR; TRANSCRIPTION FACTOR;

EID: 27944449787     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2005-03-1113     Document Type: Article
Times cited : (163)

References (55)
  • 1
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med. 1997;3:730-737.
    • (1997) Nat Med , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 2
    • 0034141934 scopus 로고    scopus 로고
    • A primitive hematopoietic cell is the target for the leukemic transformation in human philadelphia-positive acute lymphoblastic leukemia
    • Cobaleda C, Gutierrez-Cianca N, Perez-Losada J, et al. A primitive hematopoietic cell is the target for the leukemic transformation in human philadelphia-positive acute lymphoblastic leukemia. Blood. 2000;95:1007-1013.
    • (2000) Blood , vol.95 , pp. 1007-1013
    • Cobaleda, C.1    Gutierrez-Cianca, N.2    Perez-Losada, J.3
  • 5
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 6
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • Lapidot T, Sirard C, Vormoor J, et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature. 1994;367:645-648.
    • (1994) Nature , vol.367 , pp. 645-648
    • Lapidot, T.1    Sirard, C.2    Vormoor, J.3
  • 7
    • 3943088431 scopus 로고    scopus 로고
    • Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
    • Jamieson CH, Ailles LE, Dylla SJ, et al. Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med. 2004;351:657-667.
    • (2004) N Engl J Med , vol.351 , pp. 657-667
    • Jamieson, C.H.1    Ailles, L.E.2    Dylla, S.J.3
  • 8
    • 0346100567 scopus 로고    scopus 로고
    • Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors
    • Cozzio A, Passegue E, Ayton PM, Karsunky H, Cleary ML, Weissman IL. Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes Dev. 2003;17:3029-3035.
    • (2003) Genes Dev , vol.17 , pp. 3029-3035
    • Cozzio, A.1    Passegue, E.2    Ayton, P.M.3    Karsunky, H.4    Cleary, M.L.5    Weissman, I.L.6
  • 9
    • 19944385935 scopus 로고    scopus 로고
    • MOZTIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors
    • Huntly BJ, Shigematsu H, Deguchi K, et al. MOZTIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors. Cancer Cell. 2004;6:587-596.
    • (2004) Cancer Cell , vol.6 , pp. 587-596
    • Huntly, B.J.1    Shigematsu, H.2    Deguchi, K.3
  • 10
    • 0026599120 scopus 로고
    • Expression of the Evi-1 zinc finger gene in 32Dc13 myeloid cells blocks granulocytic differentiation in response to granulocyte colony-stimulating factor
    • Morishita K, Parganas E, Matsugi T, Ihle JN. Expression of the Evi-1 zinc finger gene in 32Dc13 myeloid cells blocks granulocytic differentiation in response to granulocyte colony-stimulating factor. Mol Cell Biol. 1992;12:183-189.
    • (1992) Mol Cell Biol , vol.12 , pp. 183-189
    • Morishita, K.1    Parganas, E.2    Matsugi, T.3    Ihle, J.N.4
  • 12
    • 0034964286 scopus 로고    scopus 로고
    • Transposition and gene disruption in the male germline of the mouse
    • Dupuy AJ, Fritz S, Largaespada DA. Transposition and gene disruption in the male germline of the mouse. Genesis. 2001;30:82-88.
    • (2001) Genesis , vol.30 , pp. 82-88
    • Dupuy, A.J.1    Fritz, S.2    Largaespada, D.A.3
  • 13
    • 0038516237 scopus 로고    scopus 로고
    • Bcl11a is essential for normal lymphoid development
    • Liu P, Keller JR, Ortiz M, et al. Bcl11a is essential for normal lymphoid development. Nat Immunol. 2003;4:525-532.
    • (2003) Nat Immunol , vol.4 , pp. 525-532
    • Liu, P.1    Keller, J.R.2    Ortiz, M.3
  • 14
    • 0025695582 scopus 로고
    • Embryonic stem cell virus, a recombinant murine retrovirus with expression in embryonic stem cells
    • U S A
    • Grez M, Akgun E, Hilberg F, Ostertag W. Embryonic stem cell virus, a recombinant murine retrovirus with expression in embryonic stem cells. Proc Natl Acad Sci U S A. 1990;87:9202-9206.
    • (1990) Proc Natl Acad Sci , vol.87 , pp. 9202-9206
    • Grez, M.1    Akgun, E.2    Hilberg, F.3    Ostertag, W.4
  • 16
    • 0026672334 scopus 로고
    • Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus
    • Hawley RG, Fong AZ, Burns BF, Hawley TS. Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus. J Exp Med. 1992;176:1149-1163.
    • (1992) J Exp Med , vol.176 , pp. 1149-1163
    • Hawley, R.G.1    Fong, A.Z.2    Burns, B.F.3    Hawley, T.S.4
  • 17
    • 0032544064 scopus 로고    scopus 로고
    • Representational difference analysis of a committed myeloid progenitor cell line reveals evidence for bilineage potential
    • U S A
    • Lawson ND, Berliner N. Representational difference analysis of a committed myeloid progenitor cell line reveals evidence for bilineage potential. Proc Natl Acad Sci U S A. 1998;95:10129-10133.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 10129-10133
    • Lawson, N.D.1    Berliner, N.2
  • 19
    • 0027943844 scopus 로고
    • Identification of a breakpoint cluster region 3′ of the ribophorin I gene at 3q21 associated with the transcriptional activation of the EVI1 gene in acute myelogenous leukemias with inv(3)(q21q26)
    • Suzukawa K, Parganas E, Gajjar A, et al. Identification of a breakpoint cluster region 3′ of the ribophorin I gene at 3q21 associated with the transcriptional activation of the EVI1 gene in acute myelogenous leukemias with inv(3)(q21q26). Blood. 1994;84:2681-2688.
    • (1994) Blood , vol.84 , pp. 2681-2688
    • Suzukawa, K.1    Parganas, E.2    Gajjar, A.3
  • 20
    • 0026503441 scopus 로고
    • Activation of EVI1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26
    • U S A
    • Morishita K, Parganas E, William CL, et al. Activation of EVI1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26. Proc Natl Acad Sci U S A. 1992;89:3937-3941.
    • (1992) Proc Natl Acad Sci , vol.89 , pp. 3937-3941
    • Morishita, K.1    Parganas, E.2    William, C.L.3
  • 21
    • 0027373453 scopus 로고
    • Expression of the EVI1 gene in chronic myelogenous leukemia in blast crisis
    • Russell M, Thompson F, Spier C, Taetle R. Expression of the EVI1 gene in chronic myelogenous leukemia in blast crisis. Leukemia. 1993;7:1654-1657.
    • (1993) Leukemia , vol.7 , pp. 1654-1657
    • Russell, M.1    Thompson, F.2    Spier, C.3    Taetle, R.4
  • 22
    • 0034332196 scopus 로고    scopus 로고
    • A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells
    • Mochizuki N, Shimizu S, Nagasawa T, et al. A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells. Blood. 2000;96:3209-3214.
    • (2000) Blood , vol.96 , pp. 3209-3214
    • Mochizuki, N.1    Shimizu, S.2    Nagasawa, T.3
  • 23
    • 0030272508 scopus 로고    scopus 로고
    • The B-lymphocyte maturation promoting transcription factor BLIMP1/PRDI-BF1 maps to D6S447 on human chromosome 6q21-q22.1 and the syntenic region of mouse chromosome 10
    • Mock BA, Liu L, LePaslier D, Huang S. The B-lymphocyte maturation promoting transcription factor BLIMP1/PRDI-BF1 maps to D6S447 on human chromosome 6q21-q22.1 and the syntenic region of mouse chromosome 10. Genomics. 1996;37:24-28.
    • (1996) Genomics , vol.37 , pp. 24-28
    • Mock, B.A.1    Liu, L.2    LePaslier, D.3    Huang, S.4
  • 24
    • 0032569014 scopus 로고    scopus 로고
    • The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression
    • Huang S, Shao G, Liu L. The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression. J Biol Chem. 1998;273:15933-15939.
    • (1998) J Biol Chem , vol.273 , pp. 15933-15939
    • Huang, S.1    Shao, G.2    Liu, L.3
  • 25
    • 0033967477 scopus 로고    scopus 로고
    • The yin-yang of PR-domain family genes in tumorigenesis
    • Jiang GL, Huang S. The yin-yang of PR-domain family genes in tumorigenesis. Histol Histopathol. 2000;15:109-117.
    • (2000) Histol Histopathol , vol.15 , pp. 109-117
    • Jiang, G.L.1    Huang, S.2
  • 26
    • 0142183452 scopus 로고    scopus 로고
    • A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation
    • Nishikata I, Sasaki H, Iga M, et al. A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation. Blood. 2003;102:3323-3332.
    • (2003) Blood , vol.102 , pp. 3323-3332
    • Nishikata, I.1    Sasaki, H.2    Iga, M.3
  • 27
    • 18744373853 scopus 로고    scopus 로고
    • MLL targets SET domain methyltransferase activity to Hox gene promoters
    • Milne TA, Briggs SD, Brock HW, et al. MLL targets SET domain methyltransferase activity to Hox gene promoters. Mol Cell. 2002;10:1107-1117.
    • (2002) Mol Cell , vol.10 , pp. 1107-1117
    • Milne, T.A.1    Briggs, S.D.2    Brock, H.W.3
  • 30
    • 3042642320 scopus 로고    scopus 로고
    • Identification of a novel fusion gene in a pre-B acute lymphoblastic leukemia with t(1;19)(q23;p13)
    • Yuki Y, Imoto I, Imaizumi M, et al. Identification of a novel fusion gene in a pre-B acute lymphoblastic leukemia with t(1;19)(q23;p13). Cancer Sci. 2004;95:503-507.
    • (2004) Cancer Sci , vol.95 , pp. 503-507
    • Yuki, Y.1    Imoto, I.2    Imaizumi, M.3
  • 31
    • 0029942842 scopus 로고    scopus 로고
    • Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
    • Pear WS, Aster JC, Scott ML, et al. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J Exp Med. 1996;183:2283-2291.
    • (1996) J Exp Med , vol.183 , pp. 2283-2291
    • Pear, W.S.1    Aster, J.C.2    Scott, M.L.3
  • 32
    • 0033694305 scopus 로고    scopus 로고
    • Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling
    • Varnum-Finney B, Xu L, Brashem-Stein C, et al. Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling. Nat Med. 2000;6:1278-1281.
    • (2000) Nat Med , vol.6 , pp. 1278-1281
    • Varnum-Finney, B.1    Xu, L.2    Brashem-Stein, C.3
  • 33
    • 0031050261 scopus 로고    scopus 로고
    • Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex
    • Alkema MJ, Bronk M, Verhoeven E, et al. Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex. Genes Dev. 1997;11:226-240.
    • (1997) Genes Dev , vol.11 , pp. 226-240
    • Alkema, M.J.1    Bronk, M.2    Verhoeven, E.3
  • 34
    • 0038349957 scopus 로고    scopus 로고
    • Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
    • Park IK, Qian D, Kiel M, et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature. 2003;423:302-305.
    • (2003) Nature , vol.423 , pp. 302-305
    • Park, I.K.1    Qian, D.2    Kiel, M.3
  • 35
    • 0033569429 scopus 로고    scopus 로고
    • Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF
    • Jacobs JJ, Scheijen B, Voncken JW, Kieboom K, Berns A, van Lohuizen M. Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF. Genes Dev. 1999;13:2678-2690.
    • (1999) Genes Dev , vol.13 , pp. 2678-2690
    • Jacobs, J.J.1    Scheijen, B.2    Voncken, J.W.3    Kieboom, K.4    Berns, A.5    Van Lohuizen, M.6
  • 36
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature. 2003;423:255-260.
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 37
    • 0027267480 scopus 로고
    • Loss of erythropoietin responsiveness in erythroid progenitors due to expression of the Evi-1 myeloid-transforming gene
    • U S A
    • Kreider BL, Orkin SH, Ihle JN. Loss of erythropoietin responsiveness in erythroid progenitors due to expression of the Evi-1 myeloid-transforming gene. Proc Natl Acad Sci U S A. 1993;90:6454-6458.
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 6454-6458
    • Kreider, B.L.1    Orkin, S.H.2    Ihle, J.N.3
  • 38
    • 0032723317 scopus 로고    scopus 로고
    • Forced expression of the leukemia-associated gene EVI1 in ES cells: A model for myeloid leukemia with 3q26 rearrangements
    • Sitailo S, Sood R, Barton K, Nucifora G. Forced expression of the leukemia-associated gene EVI1 in ES cells: a model for myeloid leukemia with 3q26 rearrangements. Leukemia. 1999;13:1639-1645.
    • (1999) Leukemia , vol.13 , pp. 1639-1645
    • Sitailo, S.1    Sood, R.2    Barton, K.3    Nucifora, G.4
  • 39
    • 0347379927 scopus 로고    scopus 로고
    • EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity
    • Chi Y, Senyuk V, Chakraborty S, Nucifora G. EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity. J Biol Chem. 2003;278:49806-49811.
    • (2003) J Biol Chem , vol.278 , pp. 49806-49811
    • Chi, Y.1    Senyuk, V.2    Chakraborty, S.3    Nucifora, G.4
  • 40
    • 25144490586 scopus 로고    scopus 로고
    • Recurrent retroviral vector integration at the MDS1-EVI1 locus in non-human primate hematopoietic cells
    • Prepublished June 2, as DOI:10.1182/blood-2005-03-1115
    • Calmels B, Ferguson C, Laukkanen MO, et al. Recurrent retroviral vector integration at the MDS1-EVI1 locus in non-human primate hematopoietic cells. Blood. Prepublished June 2, 2005, as DOI:10.1182/blood-2005-03-1115.
    • (2005) Blood
    • Calmels, B.1    Ferguson, C.2    Laukkanen, M.O.3
  • 41
    • 0037134031 scopus 로고    scopus 로고
    • Murine leukemia induced by retroviral gene marking
    • Li Z, Dullmann J, Schiedlmeier B, et al. Murine leukemia induced by retroviral gene marking. Science. 2002;296:497.
    • (2002) Science , vol.296 , pp. 497
    • Li, Z.1    Dullmann, J.2    Schiedlmeier, B.3
  • 42
  • 43
    • 10744221858 scopus 로고    scopus 로고
    • Association of 3q21q26 syndrome with different RPN1/EVI1 fusion transcripts
    • Martinelli G, Ottaviani E, Buonamici S, et al. Association of 3q21q26 syndrome with different RPN1/EVI1 fusion transcripts. Haematologica. 2003;88:1221-1228.
    • (2003) Haematologica , vol.88 , pp. 1221-1228
    • Martinelli, G.1    Ottaviani, E.2    Buonamici, S.3
  • 44
    • 0028065441 scopus 로고
    • Expression of EVI1 in myelodysplastic syndromes and other hematologic malignancies without 3q26 translocations
    • Russell M, List A, Greenberg P, et al. Expression of EVI1 in myelodysplastic syndromes and other hematologic malignancies without 3q26 translocations. Blood. 1994;84:1243-1248.
    • (1994) Blood , vol.84 , pp. 1243-1248
    • Russell, M.1    List, A.2    Greenberg, P.3
  • 45
    • 85047694750 scopus 로고    scopus 로고
    • EVI1 induces myelodysplastic syndrome in mice
    • Buonamici S, Li D, Chi Y, et al. EVI1 induces myelodysplastic syndrome in mice. J Clin Invest. 2004;114:713-719.
    • (2004) J Clin Invest , vol.114 , pp. 713-719
    • Buonamici, S.1    Li, D.2    Chi, Y.3
  • 46
    • 0022383747 scopus 로고
    • Rearrangements of chromosome 3 involving bands 3q21 and 3q26 are associated with normal or elevated platelet counts in acute nonlymphocytic leukemia
    • Bitter MA, Neilly ME, Le Beau MM, Pearson MG, Rowley JD. Rearrangements of chromosome 3 involving bands 3q21 and 3q26 are associated with normal or elevated platelet counts in acute nonlymphocytic leukemia. Blood. 1985;66:1362-1370.
    • (1985) Blood , vol.66 , pp. 1362-1370
    • Bitter, M.A.1    Neilly, M.E.2    Le Beau, M.M.3    Pearson, M.G.4    Rowley, J.D.5
  • 47
    • 0032833342 scopus 로고    scopus 로고
    • 3q21 and 3q26 cytogenetic abnormalities in acute myeloblastic leukemia: Biological and clinical features
    • Testoni N, Borsaru G, Martinelli G, et al. 3q21 and 3q26 cytogenetic abnormalities in acute myeloblastic leukemia: biological and clinical features. Haematologica. 1999;84:690-694.
    • (1999) Haematologica , vol.84 , pp. 690-694
    • Testoni, N.1    Borsaru, G.2    Martinelli, G.3
  • 48
    • 0022541462 scopus 로고
    • Chromosome 3q21 abnormalities associated with hyperactive thrombopoiesis in acute blastic transformation of chronic myeloid leukemia
    • Bernstein R, Bagg A, Pinto M, Lewis D, Mendelow B. Chromosome 3q21 abnormalities associated with hyperactive thrombopoiesis in acute blastic transformation of chronic myeloid leukemia. Blood. 1986;68:652-657.
    • (1986) Blood , vol.68 , pp. 652-657
    • Bernstein, R.1    Bagg, A.2    Pinto, M.3    Lewis, D.4    Mendelow, B.5
  • 49
    • 0036202470 scopus 로고    scopus 로고
    • Cytogenetic and molecular genetic evolution of chronic myeloid leukemia
    • Johansson B, Fioretos T, Mitelman F. Cytogenetic and molecular genetic evolution of chronic myeloid leukemia. Acta Haematol. 2002;107:76-94.
    • (2002) Acta Haematol , vol.107 , pp. 76-94
    • Johansson, B.1    Fioretos, T.2    Mitelman, F.3
  • 50
    • 0029938547 scopus 로고    scopus 로고
    • Increased Evi-1 expression is frequently observed in blastic crisis of chronic myelocytic leukemia
    • Ogawa S, Kurokawa M, Tanaka T, et al. Increased Evi-1 expression is frequently observed in blastic crisis of chronic myelocytic leukemia. Leukemia. 1996;10:788-794.
    • (1996) Leukemia , vol.10 , pp. 788-794
    • Ogawa, S.1    Kurokawa, M.2    Tanaka, T.3
  • 52
    • 0032126364 scopus 로고    scopus 로고
    • Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia
    • Traver D, Akashi K, Weissman IL, Lagasse E. Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia. Immunity. 1998;9:47-57.
    • (1998) Immunity , vol.9 , pp. 47-57
    • Traver, D.1    Akashi, K.2    Weissman, I.L.3    Lagasse, E.4
  • 54
    • 0035910748 scopus 로고    scopus 로고
    • BCL-2 cooperates with promyelocytic leukemia retinoic acid receptor alpha chimeric protein (PMLRARalpha) to block neutrophil differentiation and initiate acute leukemia
    • Kogan SC, Brown DE, Shultz DB, et al. BCL-2 cooperates with promyelocytic leukemia retinoic acid receptor alpha chimeric protein (PMLRARalpha) to block neutrophil differentiation and initiate acute leukemia. J Exp Med. 2001;193:531-543.
    • (2001) J Exp Med , vol.193 , pp. 531-543
    • Kogan, S.C.1    Brown, D.E.2    Shultz, D.B.3
  • 55
    • 0032125682 scopus 로고    scopus 로고
    • Sustained gene expression in retrovirally transduced, engrafting human hematopoietic stem cells and their lympho-myeloid progeny
    • Cheng L, Du C, Lavau C, et al. Sustained gene expression in retrovirally transduced, engrafting human hematopoietic stem cells and their lympho-myeloid progeny. Blood. 1998;92:83-92.
    • (1998) Blood , vol.92 , pp. 83-92
    • Cheng, L.1    Du, C.2    Lavau, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.