-
1
-
-
0037129435
-
Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy
-
Hacein-Bey-Abina, S., et al. (2002). Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy. N. Engl. J. Med. 346: 1185-1193.
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 1185-1193
-
-
Hacein-Bey-Abina, S.1
-
2
-
-
0037189401
-
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning
-
Aiuti, A., et al. (2002). Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning. Science 296: 2410-2413.
-
(2002)
Science
, vol.296
, pp. 2410-2413
-
-
Aiuti, A.1
-
3
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
Hacein-Bey-Abina, S., et al. (2003). LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302: 415-419.
-
(2003)
Science
, vol.302
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
-
4
-
-
0037448352
-
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina, S., et al. (2003). A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N. Engl. J. Med. 348: 255-256.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 255-256
-
-
Hacein-Bey-Abina, S.1
-
5
-
-
0042738935
-
Occurrence of leukaemia following gene therapy of X-linked SCID
-
Kohn, D. B., Sadelain, M., and Glorioso, J. C. (2003). Occurrence of leukaemia following gene therapy of X-linked SCID. Nat. Rev. Cancer 3: 477-488.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 477-488
-
-
Kohn, D.B.1
Sadelain, M.2
Glorioso, J.C.3
-
6
-
-
0037134031
-
Murine leukemia induced by retroviral gene marking
-
Li, Z., et al. (2002). Murine leukemia induced by retroviral gene marking. Science 296: 497.
-
(2002)
Science
, vol.296
, pp. 497
-
-
Li, Z.1
-
7
-
-
10744233858
-
American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells
-
Kohn, D. B., et al. (2003). American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells. Mol. Ther. 8: 180-187.
-
(2003)
Mol. Ther.
, vol.8
, pp. 180-187
-
-
Kohn, D.B.1
-
8
-
-
0035831610
-
An update on the use of non-human primate models for preclinical testing of gene therapy approaches targeting hematopoietic cells
-
Donahue, R. E., and Dunbar, C. E. (2001). An update on the use of non-human primate models for preclinical testing of gene therapy approaches targeting hematopoietic cells. Hum. Gene Ther. 12: 607-617.
-
(2001)
Hum. Gene Ther.
, vol.12
, pp. 607-617
-
-
Donahue, R.E.1
Dunbar, C.E.2
-
9
-
-
0037108189
-
Polyclonal long-term repopulating stem cell clones in a primate model
-
Schmidt, M., et al. (2002). Polyclonal long-term repopulating stem cell clones in a primate model. Blood 100: 2737-2743.
-
(2002)
Blood
, vol.100
, pp. 2737-2743
-
-
Schmidt, M.1
-
10
-
-
0037071417
-
Genetic marking as an approach to studying in vivo hematopoiesis: Progress in the non-human primate model
-
Shi, P., Hematti, P., von Kalle, C., and Dunbar, C. (2002). Genetic marking as an approach to studying in vivo hematopoiesis: progress in the non-human primate model. Oncogene 21: 3274-3283.
-
(2002)
Oncogene
, vol.21
, pp. 3274-3283
-
-
Shi, P.1
Hematti, P.2
von Kalle, C.3
Dunbar, C.4
-
11
-
-
0032188998
-
Transduction of murine bone marrow cells with an MDR1 vector enables ex vivo stem cell expansion, but these expanded grafts cause a myeloproliferative syndrome in transplanted mice
-
Bunting, K. D., Galipeau, J., Topham, D., Benaim, E., and Sorrentino, B. P. (1998). Transduction of murine bone marrow cells with an MDR1 vector enables ex vivo stem cell expansion, but these expanded grafts cause a myeloproliferative syndrome in transplanted mice. Blood 92: 2269-2279.
-
(1998)
Blood
, vol.92
, pp. 2269-2279
-
-
Bunting, K.D.1
Galipeau, J.2
Topham, D.3
Benaim, E.4
Sorrentino, B.P.5
-
12
-
-
0033168346
-
Effect of MDR1 gene transduction on engraftment and expansion of hematopoietic progenitor cells during breast cancer chemotherapy
-
Moscow, J. A., et al. (1999). Effect of MDR1 gene transduction on engraftment and expansion of hematopoietic progenitor cells during breast cancer chemotherapy. Blood 94: 52-61.
-
(1999)
Blood
, vol.94
, pp. 52-61
-
-
Moscow, J.A.1
-
13
-
-
0035869398
-
The effect of multidrug-resistance 1 gene versus neo transduction on ex vivo and in vivo expansion of rhesus macaque hematopoietic repopulating cells
-
Sellers, S. E., et al. (2001). The effect of multidrug-resistance 1 gene versus neo transduction on ex vivo and in vivo expansion of rhesus macaque hematopoietic repopulating cells. Blood 97: 1888-1891.
-
(2001)
Blood
, vol.97
, pp. 1888-1891
-
-
Sellers, S.E.1
-
14
-
-
0032529523
-
Ex vivo expansion of genetically marked rhesus peripheral blood progenitor cells results in diminished long-term repopulating ability
-
Tisdale, J. F., et al. (1998). Ex vivo expansion of genetically marked rhesus peripheral blood progenitor cells results in diminished long-term repopulating ability. Blood 92: 1131-1141.
-
(1998)
Blood
, vol.92
, pp. 1131-1141
-
-
Tisdale, J.F.1
-
15
-
-
0032531012
-
Improved gene transfer into baboon marrow repopulating cells using recombinant human fibronectin fragment CH-296 in combination with interleukin-6, stem cell factor, FLT-3 ligand, and megakaryocyte growth and development factor
-
Kiem, H. P., et al. (1998). Improved gene transfer into baboon marrow repopulating cells using recombinant human fibronectin fragment CH-296 in combination with interleukin-6, stem cell factor, FLT-3 ligand, and megakaryocyte growth and development factor. Blood 92: 1878-1886.
-
(1998)
Blood
, vol.92
, pp. 1878-1886
-
-
Kiem, H.P.1
-
16
-
-
0034902073
-
Avoidance of stimulation improves engraftment of cultured and retrovirally transduced hematopoietic cells in primates
-
Takatoku, M., et al. (2001). Avoidance of stimulation improves engraftment of cultured and retrovirally transduced hematopoietic cells in primates. J. Clin. Invest. 108: 447-455.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 447-455
-
-
Takatoku, M.1
-
17
-
-
0034153385
-
Prolonged high-level detection of retrovirally-marked hematopoietic cells in non-human primates after transduction of CD34+ progenitors using clinically feasible methods
-
Wu, T., et al. (2000). Prolonged high-level detection of retrovirally-marked hematopoietic cells in non-human primates after transduction of CD34+ progenitors using clinically feasible methods. Mol. Ther. 1: 285-293.
-
(2000)
Mol. Ther.
, vol.1
, pp. 285-293
-
-
Wu, T.1
-
18
-
-
0034963192
-
Gene transfer into baboon repopulating cells: A comparison of Flt-3 ligand and megakaryocyte growth and development factor versus IL-3 during ex vivo transduction
-
Kurre, P., et al. (2001). Gene transfer into baboon repopulating cells: A comparison of Flt-3 ligand and megakaryocyte growth and development factor versus IL-3 during ex vivo transduction. Mol. Ther. 3: 920-927.
-
(2001)
Mol. Ther.
, vol.3
, pp. 920-927
-
-
Kurre, P.1
-
19
-
-
0036892648
-
Highly efficient gene transfer into baboon repopulating cells using GALV-pseudotype oncoretroviral vectors produced by human packaging cells
-
Horn, P. A., Topp, M. S., Morris, J. C., Riddell, S. R., and Kiem, H.-P. (2002). Highly efficient gene transfer into baboon repopulating cells using GALV-pseudotype oncoretroviral vectors produced by human packaging cells. Blood 100: 3960-3967.
-
(2002)
Blood
, vol.100
, pp. 3960-3967
-
-
Horn, P.A.1
Topp, M.S.2
Morris, J.C.3
Riddell, S.R.4
Kiem, H.-P.5
-
20
-
-
0037443484
-
+ blood cells is superior to G-CSF or G-CSF-flt3L mobilized cells in non-human primates
-
+ blood cells is superior to G-CSF or G-CSF-flt3L mobilized cells in non-human primates. Blood 101: 2199-2205.
-
(2003)
Blood
, vol.101
, pp. 2199-2205
-
-
Hematti, P.1
-
21
-
-
0036014967
-
Plasticity and hematopoiesis: Circe's transforming potion?
-
Tisdale, J. F., and Dunbar, C. E. (2002). Plasticity and hematopoiesis: Circe's transforming potion? Curr. Opin. Hematol. 9: 268-273.
-
(2002)
Curr. Opin. Hematol.
, vol.9
, pp. 268-273
-
-
Tisdale, J.F.1
Dunbar, C.E.2
-
22
-
-
0142150965
-
Direct comparison of RD114-pseudotyped versus amphotropic pseudotyped retroviral vectors for transduction of rhesus macaque long-term repopulating cells
-
Hu, J., et al. (2003). Direct comparison of RD114-pseudotyped versus amphotropic pseudotyped retroviral vectors for transduction of rhesus macaque long-term repopulating cells. Mol. Ther. 8: 611-617.
-
(2003)
Mol. Ther.
, vol.8
, pp. 611-617
-
-
Hu, J.1
-
23
-
-
0037105534
-
Pharmacologically regulated in vivo selection in a large animal
-
Neff, T., et al. (2002). Pharmacologically regulated in vivo selection in a large animal. Blood 100: 2026-2031.
-
(2002)
Blood
, vol.100
, pp. 2026-2031
-
-
Neff, T.1
-
24
-
-
0033215519
-
The use of granulocyte colony-stimulating factor during retroviral transduction on fibronectin fragment CH-296 enhances gene transfer into hematopoietic repopulating cells in dogs
-
Goerner, M., et al. (1999). The use of granulocyte colony-stimulating factor during retroviral transduction on fibronectin fragment CH-296 enhances gene transfer into hematopoietic repopulating cells in dogs. Blood 94: 2287-2292.
-
(1999)
Blood
, vol.94
, pp. 2287-2292
-
-
Goerner, M.1
-
25
-
-
0032982664
-
Improved gene transfer into canine hematopoietic repopulating cells using CD34-enriched marrow cells in combination with a gibbon ape leukemia virus-pseudotype retroviral vector
-
Kiem, H. P., et al. (1999). Improved gene transfer into canine hematopoietic repopulating cells using CD34-enriched marrow cells in combination with a gibbon ape leukemia virus-pseudotype retroviral vector. Gene Ther. 6: 966-972.
-
(1999)
Gene Ther.
, vol.6
, pp. 966-972
-
-
Kiem, H.P.1
-
26
-
-
0035496914
-
Sustained multilineage gene persistence and expression in dogs transplanted with CD34(+) marrow cells transduced by RD114-pseudotype oncoretrovirus vectors
-
Goerner, M., et al. (2001). Sustained multilineage gene persistence and expression in dogs transplanted with CD34(+) marrow cells transduced by RD114-pseudotype oncoretrovirus vectors. Blood 98: 2065-2070.
-
(2001)
Blood
, vol.98
, pp. 2065-2070
-
-
Goerner, M.1
-
27
-
-
85030884580
-
Efficient lentiviral gene transfer to canine hematopoietic repopulating cells using an overnight transduction protocol
-
Horn, P. A., et al. (2002). Efficient lentiviral gene transfer to canine hematopoietic repopulating cells using an overnight transduction protocol. Blood 100: 687a.
-
(2002)
Blood
, vol.100
-
-
Horn, P.A.1
-
28
-
-
0037443457
-
Side effects of retroviral gene transfer into hematopoietic stem cells
-
Baum, C., et al. (2003). Side effects of retroviral gene transfer into hematopoietic stem cells. Blood 101: 2099-2114.
-
(2003)
Blood
, vol.101
, pp. 2099-2114
-
-
Baum, C.1
-
29
-
-
0037841763
-
Transcription start regions in the human genome are favored targets for MLV integration
-
Wu, X., Li, Y., Crise, B., and Burgess, S. M. (2003). Transcription start regions in the human genome are favored targets for MLV integration. Science 300: 1749-1751.
-
(2003)
Science
, vol.300
, pp. 1749-1751
-
-
Wu, X.1
Li, Y.2
Crise, B.3
Burgess, S.M.4
-
30
-
-
0026641562
-
Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer
-
Donahue, R. E., et al. (1992). Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer. J. Exp. Med. 176: 1125-1135.
-
(1992)
J. Exp. Med.
, vol.176
, pp. 1125-1135
-
-
Donahue, R.E.1
-
31
-
-
0036725051
-
New genes involved in cancer identified by retroviral tagging
-
Suzuki, T., et al. (2002). New genes involved in cancer identified by retroviral tagging. Nat. Genet. 32: 166-174.
-
(2002)
Nat. Genet.
, vol.32
, pp. 166-174
-
-
Suzuki, T.1
-
32
-
-
0030065744
-
Evidence that hematopoiesis may be a stochastic process in vivo
-
Abkowitz, J. L., Catlin, S. N., and Guttorp, P. (1996). Evidence that hematopoiesis may be a stochastic process in vivo. Nat. Med. 2: 190-196.
-
(1996)
Nat. Med.
, vol.2
, pp. 190-196
-
-
Abkowitz, J.L.1
Catlin, S.N.2
Guttorp, P.3
-
33
-
-
0026941999
-
A model for predicting the risk of cancer consequent to retroviral gene therapy
-
Moolten, F. L., and Cupples, L. A. (1996). A model for predicting the risk of cancer consequent to retroviral gene therapy. Hum. Gene Ther. 3: 479-486.
-
(1996)
Hum. Gene Ther.
, vol.3
, pp. 479-486
-
-
Moolten, F.L.1
Cupples, L.A.2
-
34
-
-
12244279028
-
Prolonged multilineage clonal hematopoiesis in a rhesus recipient of CD34 positive cells marked with an oncoretroviral vector
-
Kelly, P. F., et al. (2002). Prolonged multilineage clonal hematopoiesis in a rhesus recipient of CD34 positive cells marked with an oncoretroviral vector. Blood Cells Mol. Dis. 30: 132-143.
-
(2002)
Blood Cells Mol. Dis.
, vol.30
, pp. 132-143
-
-
Kelly, P.F.1
|