메뉴 건너뛰기




Volumn 95, Issue 1, 2000, Pages 102-110

Expansion of human cord blood CD34+CD38- cells in ex vivo culture during retroviral transduction without a corresponding increase in SCID repopulating cell (SRC) frequency: Dissociation of SRC phenotype and function

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN;

EID: 0033964863     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v95.1.102     Document Type: Article
Times cited : (213)

References (47)
  • 1
    • 0030928619 scopus 로고    scopus 로고
    • Gene therapy - Promises, problems, and prospects
    • Verma I, Somia N. Gene therapy - promises, problems, and prospects. Nature. 1996;389:239-242.
    • (1996) Nature , vol.389 , pp. 239-242
    • Verma, I.1    Somia, N.2
  • 2
    • 0027162426 scopus 로고
    • Large-scale expansion of human stem and progenitor cells from bone marrow mononuclear cells in continuous perfusion cultures
    • Koller MR, Emerson SG, Palsson BO. Large-scale expansion of human stem and progenitor cells from bone marrow mononuclear cells in continuous perfusion cultures. Blood. 1993;82:378-384.
    • (1993) Blood , vol.82 , pp. 378-384
    • Koller, M.R.1    Emerson, S.G.2    Palsson, B.O.3
  • 3
    • 0029976140 scopus 로고    scopus 로고
    • Self-renewal of primitive human cells (long term culture-initiating cells) in vitro and their expansion in defined medium
    • Petzer AL, Hogge DE, Lansdorp PM, Reid DS, Eaves CJ. Self-renewal of primitive human cells (long term culture-initiating cells) in vitro and their expansion in defined medium. Proc Natl Acad Sci U S A. 1996;93:1470-1474.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 1470-1474
    • Petzer, A.L.1    Hogge, D.E.2    Lansdorp, P.M.3    Reid, D.S.4    Eaves, C.J.5
  • 4
    • 0031000903 scopus 로고    scopus 로고
    • Extensive amplification and self-renewal of human primitive hematopoietic stem cells from cord blood
    • Piacibello W, Sanavio F, Garetto L, et al. Extensive amplification and self-renewal of human primitive hematopoietic stem cells from cord blood. Blood. 1997;89:2644-2653.
    • (1997) Blood , vol.89 , pp. 2644-2653
    • Piacibello, W.1    Sanavio, F.2    Garetto, L.3
  • 6
    • 0030221263 scopus 로고    scopus 로고
    • Normal and leukemic human stem cells assayed in SCID mice
    • Dick JE. Normal and leukemic human stem cells assayed in SCID mice. Semin Immunol. 1996;4: 197-206.
    • (1996) Semin Immunol , vol.4 , pp. 197-206
    • Dick, J.E.1
  • 7
    • 0030685762 scopus 로고    scopus 로고
    • Assay of human stem cells by repopulation of NOD/SCID mice
    • Dick JE, Bhatia M, Gan O, Kapp U, Wang JCY. Assay of human stem cells by repopulation of NOD/SCID mice. Stem Cells. 1997;15(suppl 1): 199-203.
    • (1997) Stem Cells , vol.15 , Issue.SUPPL. 1 , pp. 199-203
    • Dick, J.E.1    Bhatia, M.2    Gan, O.3    Kapp, U.4    Wang, J.C.Y.5
  • 8
    • 16144365969 scopus 로고    scopus 로고
    • Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy
    • Larochelle A, Vormoor J, Hanenberg H, et al. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: implications for gene therapy. Nat Med. 1996;2:1329-1337.
    • (1996) Nat Med , vol.2 , pp. 1329-1337
    • Larochelle, A.1    Vormoor, J.2    Hanenberg, H.3
  • 9
    • 0030911358 scopus 로고    scopus 로고
    • Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice
    • Bhatia M, Wang XY, Kapp U, Bonnet D, Dick JE. Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice. Proc Natl Acad Sci U S A. 1997;94:5320-5325.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 5320-5325
    • Bhatia, M.1    Wang, X.Y.2    Kapp, U.3    Bonnet, D.4    Dick, J.E.5
  • 10
    • 0030756218 scopus 로고    scopus 로고
    • Differential maintenance of primitive human SCID-repopulating cells, clonogenic progenitors, and long-term culture-initiating cells after incubation on human bone marrow stromal cells
    • Gan OI, Murdoch B, Larochelle A, Dick JE. Differential maintenance of primitive human SCID-repopulating cells, clonogenic progenitors, and long-term culture-initiating cells after incubation on human bone marrow stromal cells. Blood. 1997;90:641-650.
    • (1997) Blood , vol.90 , pp. 641-650
    • Gan, O.I.1    Murdoch, B.2    Larochelle, A.3    Dick, J.E.4
  • 11
    • 0030788152 scopus 로고    scopus 로고
    • Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture
    • Bhatia M, Bonnet D, Kapp U, Wang JCY, Murdoch B, Dick JE. Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture. J Exp Med. 1997;186:619-624.
    • (1997) J Exp Med , vol.186 , pp. 619-624
    • Bhatia, M.1    Bonnet, D.2    Kapp, U.3    Wang, J.C.Y.4    Murdoch, B.5    Dick, J.E.6
  • 12
    • 0030886656 scopus 로고    scopus 로고
    • Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic-scid/scid mice
    • Conneally E, Cashman J, Petzer A, Eaves CJ. Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic-scid/scid mice. Proc Natl Acad Sci U S A. 1997;94:9836-9841.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 9836-9841
    • Conneally, E.1    Cashman, J.2    Petzer, A.3    Eaves, C.J.4
  • 13
    • 0027595949 scopus 로고
    • The basic science of gene therapy
    • Mulligan R. The basic science of gene therapy. Science. 1993;260:926-932.
    • (1993) Science , vol.260 , pp. 926-932
    • Mulligan, R.1
  • 14
    • 0027443191 scopus 로고
    • Gene marking to determine whether autologous marrow infusion restores long-term hematopoiesis in cancer patients
    • Brenner MK, Rill DR, Holladay MS, et al. Gene marking to determine whether autologous marrow infusion restores long-term hematopoiesis in cancer patients. Lancet. 1993;342:1134-1137.
    • (1993) Lancet , vol.342 , pp. 1134-1137
    • Brenner, M.K.1    Rill, D.R.2    Holladay, M.S.3
  • 15
    • 85041132416 scopus 로고
    • Genetic marking shows that ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse
    • Deisseroth AB, Zu Z, Claxton D, et al Genetic marking shows that ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse. Blood. 1994;83: 3068-3076.
    • (1994) Blood , vol.83 , pp. 3068-3076
    • Deisseroth, A.B.1    Zu, Z.2    Claxton, D.3
  • 16
    • 0028864561 scopus 로고
    • Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency
    • Kohn DB, Weinberg KI, Nolta JA, et al. Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency. Nat Med. 1995;1:1017-1023.
    • (1995) Nat Med , vol.1 , pp. 1017-1023
    • Kohn, D.B.1    Weinberg, K.I.2    Nolta, J.A.3
  • 17
    • 0029068059 scopus 로고
    • Retrovirally marked CD34-enriched peripheral blood and bone marrow cells contribute to long-term engraftment after autologous transplantation
    • Dunbar CE, Cottler-Fox M, O'Shaughnessy JA, et al. Retrovirally marked CD34-enriched peripheral blood and bone marrow cells contribute to long-term engraftment after autologous transplantation. Blood. 1995;85:3048-3057.
    • (1995) Blood , vol.85 , pp. 3048-3057
    • Dunbar, C.E.1    Cottler-Fox, M.2    O'Shaughnessy, J.A.3
  • 19
    • 0032056367 scopus 로고    scopus 로고
    • Efficient retroviral-mediated gene transter to human cord blood stem cells with in vivo repopulating potential
    • Conneally E, Eaves CJ, Humphries RK. Efficient retroviral-mediated gene transter to human cord blood stem cells with in vivo repopulating potential. Blood. 1998;91:3487-3493.
    • (1998) Blood , vol.91 , pp. 3487-3493
    • Conneally, E.1    Eaves, C.J.2    Humphries, R.K.3
  • 20
    • 0032126897 scopus 로고    scopus 로고
    • low primitive cells capable of reconstituting long-term cultures in vitro and nonobese diabetic-severe combined immunodeficiency mice in vivo
    • low primitive cells capable of reconstituting long-term cultures in vitro and nonobese diabetic-severe combined immunodeficiency mice in vivo. Hum Gene Ther. 1998;9:1497-1511.
    • (1998) Hum Gene Ther , vol.9 , pp. 1497-1511
    • Marandin, A.1    Dubart, A.2    Pflumio, F.3
  • 21
    • 0032213335 scopus 로고    scopus 로고
    • High efficiency gene transfer to human hematopoietic SCID-repopulating cells under serum-free conditions
    • Schilz AJ, Brauns G, Knöß H, et al. High efficiency gene transfer to human hematopoietic SCID-repopulating cells under serum-free conditions. Blood. 1998;92:3163-3171.
    • (1998) Blood , vol.92 , pp. 3163-3171
    • Schilz, A.J.1    Brauns, G.2    Knöß, H.3
  • 22
    • 0032402140 scopus 로고    scopus 로고
    • Highly efficient transduction of the green fluorescent protein gene in human umbilical cord blood stem cells capable of cobblestone formation in long-term cultures and multilineage engraftment of immunodeficient mice
    • van Hennik PB, Verstagen MM, Bierhuizen MF, et al. Highly efficient transduction of the green fluorescent protein gene in human umbilical cord blood stem cells capable of cobblestone formation in long-term cultures and multilineage engraftment of immunodeficient mice. Blood. 1998; 92:4013-4022.
    • (1998) Blood , vol.92 , pp. 4013-4022
    • Van Hennik, P.B.1    Verstagen, M.M.2    Bierhuizen, M.F.3
  • 23
    • 0033120735 scopus 로고    scopus 로고
    • One-day ex vivo culture allows effective gene transfer into human nonobese diabetic/severe combined immune-deficient repopulating cells using high-titer vesicular stomatitis virus g protein pseudotyped retrovirus
    • Rebel VI, Tanaka M, Lee JS, et al. One-day ex vivo culture allows effective gene transfer into human nonobese diabetic/severe combined immune-deficient repopulating cells using high-titer vesicular stomatitis virus G protein pseudotyped retrovirus. Blood. 1999;93:2217-2224.
    • (1999) Blood , vol.93 , pp. 2217-2224
    • Rebel, V.I.1    Tanaka, M.2    Lee, J.S.3
  • 24
    • 0027880136 scopus 로고
    • Antigenic analysis of hematopoiesis: A review
    • Civin CI, Gore SD. Antigenic analysis of hematopoiesis: a review. J Hematother. 1993;2:137-144.
    • (1993) J Hematother , vol.2 , pp. 137-144
    • Civin, C.I.1    Gore, S.D.2
  • 27
    • 0029858685 scopus 로고    scopus 로고
    • Extended long-term culture reveals a highly quiescent and primitive human hematopoietic progenitor population
    • Hao QL, Thiemann FT, Petersen D, Smogorzewska EM, Crooks GM. Extended long-term culture reveals a highly quiescent and primitive human hematopoietic progenitor population. Blood. 1996;88:3306-3313.
    • (1996) Blood , vol.88 , pp. 3306-3313
    • Hao, Q.L.1    Thiemann, F.T.2    Petersen, D.3    Smogorzewska, E.M.4    Crooks, G.M.5
  • 28
    • 0028239418 scopus 로고
    • Expression of CD33, CD38, and HLA-DR on CD34+ human fetal liver progenitors with a high proliferate potential
    • Muench MO, Cupp J, Polakoff J, Roncarolo MG. Expression of CD33, CD38, and HLA-DR on CD34+ human fetal liver progenitors with a high proliferate potential. Blood. 1994;83:3170-3181.
    • (1994) Blood , vol.83 , pp. 3170-3181
    • Muench, M.O.1    Cupp, J.2    Polakoff, J.3    Roncarolo, M.G.4
  • 29
    • 0030775308 scopus 로고    scopus 로고
    • A GFP reporter system to assess gene transfer and expression in human hematopoietic progenitor cells
    • Cheng L, Du C, Murray D, et al. A GFP reporter system to assess gene transfer and expression in human hematopoietic progenitor cells. Gene Ther. 1997;4:1013-1022.
    • (1997) Gene Ther , vol.4 , pp. 1013-1022
    • Cheng, L.1    Du, C.2    Murray, D.3
  • 30
    • 0030920217 scopus 로고    scopus 로고
    • Leptin receptor action in hepatic cells
    • Wang Y, Kuropatwinski KK, White DW, et al. Leptin receptor action in hepatic cells. J Biol Chem. 1997;272:16,216-16,223.
    • (1997) J Biol Chem , vol.272 , pp. 16216-16223
    • Wang, Y.1    Kuropatwinski, K.K.2    White, D.W.3
  • 31
    • 0026581239 scopus 로고
    • Cytokine stimulation of multi-lineage hematopoiesis from immature human cells engrafted in SCID mice
    • Lapidot T, Pflumio F, Doedens M, Murdoch B, Williams DE, Dick JE. Cytokine stimulation of multi-lineage hematopoiesis from immature human cells engrafted in SCID mice. Science. 1992;255: 1137-1141.
    • (1992) Science , vol.255 , pp. 1137-1141
    • Lapidot, T.1    Pflumio, F.2    Doedens, M.3    Murdoch, B.4    Williams, D.E.5    Dick, J.E.6
  • 32
    • 0028024489 scopus 로고
    • Hydrocortisone differentially affects the ability of murine stromal cells and human marrow-derived adherent cells to promote the differentiation of CD34+ +/CD38- long-term culture-initiating cells
    • Croisille L, Auffray I, Katz A, Izac B, Vainchenker W, Coulombel L. Hydrocortisone differentially affects the ability of murine stromal cells and human marrow-derived adherent cells to promote the differentiation of CD34+ +/CD38- long-term culture-initiating cells. Blood. 1994;84:4116-4124.
    • (1994) Blood , vol.84 , pp. 4116-4124
    • Croisille, L.1    Auffray, I.2    Katz, A.3    Izac, B.4    Vainchenker, W.5    Coulombel, L.6
  • 33
    • 0031671642 scopus 로고    scopus 로고
    • A newly discovered class of human repopulating cells with SCID-repopulating activity
    • Bhatia M, Bonnet D, Murdoch B, Gan OI, Dick JE. A newly discovered class of human repopulating cells with SCID-repopulating activity. Nat Med. 1998;4:1038-1045.
    • (1998) Nat Med , vol.4 , pp. 1038-1045
    • Bhatia, M.1    Bonnet, D.2    Murdoch, B.3    Gan, O.I.4    Dick, J.E.5
  • 34
    • 0032994401 scopus 로고    scopus 로고
    • Cytokine treatment or accessory cells to initiate engraftment of purified primitive human hematopoietic cells transplanted at limiting doses into NOD/SCID mice
    • Bonnet D, Bhatia M, Wang JCY, Kapp U, Dick JE. Cytokine treatment or accessory cells to initiate engraftment of purified primitive human hematopoietic cells transplanted at limiting doses into NOD/SCID mice. Bone Marrow Transplant. 1999; 3:203-209.
    • (1999) Bone Marrow Transplant , vol.3 , pp. 203-209
    • Bonnet, D.1    Bhatia, M.2    Wang, J.C.Y.3    Kapp, U.4    Dick, J.E.5
  • 35
    • 0024213526 scopus 로고
    • Engraftment of immunedeficient mice with human hematopoietic stem cells
    • Kamel-Reid S, Dick JE. Engraftment of immunedeficient mice with human hematopoietic stem cells. Science. 1988;242:1706-1709.
    • (1988) Science , vol.242 , pp. 1706-1709
    • Kamel-Reid, S.1    Dick, J.E.2
  • 36
    • 0019468220 scopus 로고
    • Limiting dilution assays for the determination of immunocompetent cell frequencies: I. Data analysis
    • Taswell C. Limiting dilution assays for the determination of immunocompetent cell frequencies: I. Data analysis. J Immunol. 1981;126:1614-1619.
    • (1981) J Immunol , vol.126 , pp. 1614-1619
    • Taswell, C.1
  • 37
    • 0029923437 scopus 로고    scopus 로고
    • Interleukin 3 or interleukin 1 abrogates the reconstituting ability of hematopoietic stem cells
    • Yonemura Y, Ku H, Hirayama F, Souza LM, Ogawa M. Interleukin 3 or interleukin 1 abrogates the reconstituting ability of hematopoietic stem cells. Proc Natl Acad Sci U S A. 1996;93:4040-4044.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 4040-4044
    • Yonemura, Y.1    Ku, H.2    Hirayama, F.3    Souza, L.M.4    Ogawa, M.5
  • 39
    • 0033032194 scopus 로고    scopus 로고
    • Characterization and retroviral transduction of an early human lymphomyeloid precursor assayed in non-switched long-term culture on murine stroma
    • Gan OI, Dorrell C, Pereira D, Ito C, Wang JCY, Dick JE. Characterization and retroviral transduction of an early human lymphomyeloid precursor assayed in non-switched long-term culture on murine stroma. Exp Hematol. 1999;27:1097-1106.
    • (1999) Exp Hematol , vol.27 , pp. 1097-1106
    • Gan, O.I.1    Dorrell, C.2    Pereira, D.3    Ito, C.4    Wang, J.C.Y.5    Dick, J.E.6
  • 40
    • 0029875622 scopus 로고    scopus 로고
    • Retroviral transduction of CD34-enriched hematopoietic progenitor cells under serum-free conditions
    • Sekhar M, Kotani H, Doren S, Agarwal R, McGarrity G, Dunbar CE. Retroviral transduction of CD34-enriched hematopoietic progenitor cells under serum-free conditions. Hum Gene Ther. 1996;7:33-38.
    • (1996) Hum Gene Ther , vol.7 , pp. 33-38
    • Sekhar, M.1    Kotani, H.2    Doren, S.3    Agarwal, R.4    McGarrity, G.5    Dunbar, C.E.6
  • 41
    • 17344371126 scopus 로고    scopus 로고
    • Efficient serum-free retroviral gene transfer into primitive human hematopoietic progenitor cells by a defined, high-titer, nonconcentrated vector-containing medium
    • Glimm H, Flugge K, Mobest D, et al. Efficient serum-free retroviral gene transfer into primitive human hematopoietic progenitor cells by a defined, high-titer, nonconcentrated vector-containing medium. Hum Gene Ther. 1998;9:771-778.
    • (1998) Hum Gene Ther , vol.9 , pp. 771-778
    • Glimm, H.1    Flugge, K.2    Mobest, D.3
  • 42
    • 0028965127 scopus 로고
    • lo human marrow cells after in vitro cytokine exposure
    • lo human marrow cells after in vitro cytokine exposure. Blood. 1995;85:1480-1487.
    • (1995) Blood , vol.85 , pp. 1480-1487
    • Reems, J.A.1    Torok-Storb, B.2
  • 43
    • 0031967376 scopus 로고    scopus 로고
    • Multiparameter-fluorescence activated cell sorting analysis of retroviral vector gene transfer into primitive umbilical cord blood cells
    • McCowage GB, Phillips KL, Gentry TL, et al. Multiparameter-fluorescence activated cell sorting analysis of retroviral vector gene transfer into primitive umbilical cord blood cells. Exp Hematol. 1998;26:288-298.
    • (1998) Exp Hematol , vol.26 , pp. 288-298
    • McCowage, G.B.1    Phillips, K.L.2    Gentry, T.L.3
  • 44
    • 0028180982 scopus 로고
    • + cells in serum-free cultures containing steel factor, interleukin-6, and erythropoietin with maintenance of cell with long-term reconstituting potential
    • + cells in serum-free cultures containing steel factor, interleukin-6, and erythropoietin with maintenance of cell with long-term reconstituting potential. Blood. 1994;83:128-136.
    • (1994) Blood , vol.83 , pp. 128-136
    • Rebel, V.I.1    Dragowska, W.2    Eaves, C.J.3    Humphries, R.K.4    Lansdorp, P.M.5
  • 45
    • 0030820079 scopus 로고    scopus 로고
    • The CD38 lymphocyte differentiation marker: New insight into its ectoenzymatic activity and its role as a signal transducer
    • Shubinsky G, Schlesinger M. The CD38 lymphocyte differentiation marker: new insight into its ectoenzymatic activity and its role as a signal transducer. Immunity. 1997;7:315-324.
    • (1997) Immunity , vol.7 , pp. 315-324
    • Shubinsky, G.1    Schlesinger, M.2
  • 46
    • 0030579168 scopus 로고    scopus 로고
    • The mechanism of interleukin-4-induced downregulation of CD38 on human B cells
    • Shubinsky G, Schlesinger M. The mechanism of interleukin-4-induced downregulation of CD38 on human B cells. Cell Immunol. 1997;173:87-95.
    • (1997) Cell Immunol , vol.173 , pp. 87-95
    • Shubinsky, G.1    Schlesinger, M.2
  • 47
    • 0033524834 scopus 로고    scopus 로고
    • Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4
    • Peled A, Petit I, Kollet O, et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science. 1999;283: 845-848.
    • (1999) Science , vol.283 , pp. 845-848
    • Peled, A.1    Petit, I.2    Kollet, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.