Double suicide gene (cytosine deaminase and herpes simplex virus thymidine kinase) but not single gene transfer allows reliable elimination of tumor cells in vivo

Human Gene Therapy

Volumn 9, Issue 6, 1998, Pages 855-865

  Uckert, W ^a   Kammertons T ^a   Haack, K ^b   Qin, Z ^a   Gebert, J ^b   Schendel, D J ^c   Blankenstein, T ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; CYTOSINE DEAMINASE; DRUG METABOLITE; FLUCYTOSINE; GANCICLOVIR; PRODRUG; TOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST ADENOCARCINOMA; CANCER IMMUNIZATION; CELL KILLING; GENE TARGETING; GENE TRANSFER; HERPES SIMPLEX VIRUS; MOUSE; NONHUMAN; SUBCUTANEOUS DRUG ADMINISTRATION; SUICIDE GENE; T LYMPHOCYTE; TUMOR CELL; TUMOR IMMUNITY; TUMOR VOLUME; VACCINATION;

ANIMALIA; HERPES; MURINAE; MUS MUSCULUS; SIMPLEXVIRUS;

EID: 0032502844     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1998.9.6-855     Document Type: Article

References (10)

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