A method to sequence and quantify DNA integration for monitoring outcome in gene therapy

Nucleic Acids Research

Volumn 39, Issue 11, 2011, Pages

  Brady, Troy ^a   Roth, Shoshannah L ^a   Malani, Nirav ^a   Wang, Gary P ^a   Berry, Charles C ^b   Leboulch, Philippe ^c,d,e   Hacein Bey Abina, Salima ^f   Cavazzana Calvo, Marina ^f   Papapetrou, Eirini P ^g,h   Sadelain, Michel ^g,h   Savilahti, Harri ⁱ   Bushman, Frederic D ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CEA   (France)

^d Institute of Emerging Diseases and Innovative Therapies   (France)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f HÔPITAL NECKER ENFANTS MALADES   (France)

^g Center for Cell Engineering   (United States)

^h MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

ⁱ UNIVERSITY OF TURKU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; RETROVIRUS VECTOR; TRANSPOSASE;

ARTICLE; BACTERIOPHAGE MU; BETA THALASSEMIA; CD3+ T LYMPHOCYTE; DNA BARCODING; DNA INTEGRATION; DNA SEQUENCE; DNA TRANSPOSITION; GENE; GENE THERAPY; HMGA2 GENE; HUMAN; HUMAN CELL; IN VITRO STUDY; INTEGRATION SITE SEQUENCE; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PYROSEQUENCING; RESTRICTION MAPPING; SEVERE COMBINED IMMUNODEFICIENCY; UNINDEXED SEQUENCE;

BACTERIOPHAGE MU; CELL LINE; GENE TARGETING; GENE THERAPY; HUMANS; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA;

ENTEROBACTERIA PHAGE MU;

EID: 79959469934     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr140     Document Type: Article

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