Tanshinone i increases CYP1A2 protein expression and enzyme activity in primary rat hepatocytes

Phytomedicine

Volumn 19, Issue 2, 2012, Pages 169-176

  Lee, Wayne Y W ^a   Zhou, Xuelin ^a   Or, Penelope M Y ^a   Kwan, Yiu Wa ^a   Yeung, John H K ^a  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

CYP1A2 induction; Primary rat hepatocytes; Salvia miltiorrhiza; Tanshinone I

Indexed keywords

3 (3,4 DIHYDROXYPHENYL)LACTIC ACID; AROMATIC HYDROCARBON RECEPTOR; CRYPTOTANSHINONE; CYTOCHROME P450 1A2; DIHYDROTANSHINONE; MESSENGER RNA; PHENACETIN; SALVIA MILTIORRHIZA EXTRACT; SALVIANOLIC ACID B; TANSHINONE I; TANSHINONE IIA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DEETHYLATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME MECHANISM; HERB DRUG INTERACTION; IC 50; LIVER CELL; MALE; NONHUMAN; PLANT ROOT; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SALVIA MILTIORRHIZA; UPREGULATION;

ANIMALS; BENZOFURANS; CELL SURVIVAL; CYTOCHROMES; DITERPENES, ABIETANE; DRUGS, CHINESE HERBAL; ENZYME ACTIVATION; ENZYME INDUCTION; ETHANOL; HEPATOCYTES; MALE; PHENACETIN; PHENANTHRENES; PHENANTHROLINES; PRIMARY CELL CULTURE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; TACRINE;

RATTUS; SALVIA MILTIORRHIZA;

EID: 83655191991     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2011.07.006     Document Type: Article

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