Re-evaluation of tacrine hepatotoxicity using gel entrapped hepatocytes

Toxicology Letters

Volumn 168, Issue 2, 2007, Pages 140-147

  Meng, Qin ^a   Ru, Jianghua ^a   Zhang, Guoliang ^a,b   Shen, Chong ^a   Schmitmeier, Stephanie ^c   Bader, Augustinus ^c  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

^c UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

CYP 1A2; Gel entrapment; Hepatocytes; Hepatotoxicity; Hollow fibers; Tacrine

Indexed keywords

ALBUMIN; CYTOCHROME P450 1A2; CYTOCHROME P450 1A2 INHIBITOR; FLUVOXAMINE; GLUTATHIONE; GLYCYRRHETINIC ACID; METHYLTHIAZOLYLTETRAZOLIUM; SCAVENGER; TACRINE; TETRAZOLIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GEL ENTRAPMENT CULTURE; HOLLOW FIBER; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER TOXICITY; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT;

ALBUMINS; ANIMALS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; CELL SURVIVAL; CELLS, CULTURED; CHOLINESTERASE INHIBITORS; CYTOCHROME P-450 CYP1A2; FEMALE; FLUVOXAMINE; GELS; GLUTATHIONE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; GLYCYRRHETINIC ACID; HEPATITIS, TOXIC; HEPATOCYTES; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TACRINE; TETRAZOLIUM SALTS; THIAZOLES;

RATTUS;

EID: 33845984024     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2006.11.009     Document Type: Article

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