-
1
-
-
0034935316
-
Low cyclosporin-A level due to Saint-John's-wort in heart transplant patients
-
Ahmed SM, Banner NR, Dubrey SW. 2001. Low cyclosporin-A level due to Saint-John's-wort in heart transplant patients. J Heart Lung Transplant 20: 795.
-
(2001)
J Heart Lung Transplant
, vol.20
, pp. 795
-
-
Ahmed, S.M.1
Banner, N.R.2
Dubrey, S.W.3
-
2
-
-
1642538952
-
Different structural requirements of the ligand binding domain of the aryl hydrocarbon receptor for high- and low-affinity ligand binding and receptor activation
-
Backlund M, Ingelman-Sundberg M. 2004. Different structural requirements of the ligand binding domain of the aryl hydrocarbon receptor for high- and low-affinity ligand binding and receptor activation. Mol Pharmacol 65: 416-425.
-
(2004)
Mol Pharmacol
, vol.65
, pp. 416-425
-
-
Backlund, M.1
Ingelman-Sundberg, M.2
-
3
-
-
2442711488
-
Molecular cloning of the guinea pig CYP1A2 gene 5′ flanking region: Identification of functional aromatic hydrocarbon response element and characterization of CYP1A2 expression in GPC16 cells
-
Black VH, Quattrochi LC. 2004. Molecular cloning of the guinea pig CYP1A2 gene 5′ flanking region: identification of functional aromatic hydrocarbon response element and characterization of CYP1A2 expression in GPC16 cells. Drug Metab Dispos 32: 595-602.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 595-602
-
-
Black, V.H.1
Quattrochi, L.C.2
-
4
-
-
31444453937
-
Validation of in vitro models used in drug metabolism and transport studies; genotyping of cytochrome P450, phase II enzymes and drug transporter polymorphism in the human hepatoma (HepG2), ovarian carcinoma (IGROV-1) and colon carcinoma (CaCo-2, LS180) cell lines
-
Brandon EFA, Bosch TM, Deenen MJ et al. 2006. Validation of in vitro models used in drug metabolism and transport studies; genotyping of cytochrome P450, phase II enzymes and drug transporter polymorphism in the human hepatoma (HepG2), ovarian carcinoma (IGROV-1) and colon carcinoma (CaCo-2, LS180) cell lines. Toxicol Appl Pharmacol 211: 1-10.
-
(2006)
Toxicol Appl Pharmacol
, vol.211
, pp. 1-10
-
-
Brandon, E.F.A.1
Bosch, T.M.2
Deenen, M.J.3
-
5
-
-
0023113788
-
Biotransformation of caffeine, paraxanthine, theophylline and theobromine by polycyclic aromatic inducible cytochrome(s) P-450 in human liver microsomes
-
Campbell ME, Grant DM, Inaba T, Kalow W. 1987. Biotransformation of caffeine, paraxanthine, theophylline and theobromine by polycyclic aromatic inducible cytochrome(s) P-450 in human liver microsomes. Drug Metab Dispos 15: 237-249.
-
(1987)
Drug Metab Dispos
, vol.15
, pp. 237-249
-
-
Campbell, M.E.1
Grant, D.M.2
Inaba, T.3
Kalow, W.4
-
6
-
-
0036136534
-
A pharmacophore for human pregnane X receptor ligands
-
Ekins S, Erickson JA. 2002. A pharmacophore for human pregnane X receptor ligands. Drug Metab Dispos 30: 96-99.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 96-99
-
-
Ekins, S.1
Erickson, J.A.2
-
7
-
-
0035152853
-
CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies
-
Engman HA, Lennernäs H, Taipalensuu J, Otter C, Leidvik B, Artursson P. 2001. CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies. J Pharm Sci 90: 1736-1751.
-
(2001)
J Pharm Sci
, vol.90
, pp. 1736-1751
-
-
Engman, H.A.1
Lennernäs, H.2
Taipalensuu, J.3
Otter, C.4
Leidvik, B.5
Artursson, P.6
-
8
-
-
0035805536
-
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin
-
Geick A, Eichelbaum M, Burk O. 2001. Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin. J Biol Chem 276: 14581-14587.
-
(2001)
J Biol Chem
, vol.276
, pp. 14581-14587
-
-
Geick, A.1
Eichelbaum, M.2
Burk, O.3
-
9
-
-
1642441388
-
The effect of echinacea (Echinacea purpurea root) on cytochrome P450 activity in vivo
-
Gorski JC, Huang SM, Pinto A, Hamman MA, Hilligoss JK, Zaheer NA, Desai M, Miller M, Hall SD. 2004. The effect of echinacea (Echinacea purpurea root) on cytochrome P450 activity in vivo. Clin Pharmacol Ther 75: 89-100.
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 89-100
-
-
Gorski, J.C.1
Huang, S.M.2
Pinto, A.3
Hamman, M.A.4
Hilligoss, J.K.5
Zaheer, N.A.6
Desai, M.7
Miller, M.8
Hall, S.D.9
-
10
-
-
0344740559
-
Induction of drug metabolism: The role of nuclear receptors
-
Handschin C, Meyer UA. 2003. Induction of drug metabolism: The role of nuclear receptors. Pharmacol Rev 55: 649-673.
-
(2003)
Pharmacol Rev
, vol.55
, pp. 649-673
-
-
Handschin, C.1
Meyer, U.A.2
-
11
-
-
0025951740
-
Detection and characterization of the Ah receptor in the human colon adenocarcinoma cell line LS180
-
Harper PA, Prokipcak RD, Bush LE, Golas CL, Okey AB. 1991. Detection and characterization of the Ah receptor in the human colon adenocarcinoma cell line LS180. Arch Biochem Biophys 290: 27-36.
-
(1991)
Arch Biochem Biophys
, vol.290
, pp. 27-36
-
-
Harper, P.A.1
Prokipcak, R.D.2
Bush, L.E.3
Golas, C.L.4
Okey, A.B.5
-
12
-
-
11144357796
-
Activators of the rat pregnane X receptor differentially modulate hepatic and intestinal gene expression
-
Hartley DP, Dai X, He YD, Carlini EJ, Wang B, Huskey SE, Ulrich RG, Rushmore TH, Evers R, Evans DC. 2004. Activators of the rat pregnane X receptor differentially modulate hepatic and intestinal gene expression. Mol Pharmacol 65: 1159-1171.
-
(2004)
Mol Pharmacol
, vol.65
, pp. 1159-1171
-
-
Hartley, D.P.1
Dai, X.2
He, Y.D.3
Carlini, E.J.4
Wang, B.5
Huskey, S.E.6
Ulrich, R.G.7
Rushmore, T.H.8
Evers, R.9
Evans, D.C.10
-
13
-
-
0038798874
-
Drug-activated nuclear receptors CAR and PXR
-
Honkakoski P, Sueyoshi T, Negishi M. 2003. Drug-activated nuclear receptors CAR and PXR. Ann Med 35: 172-182.
-
(2003)
Ann Med
, vol.35
, pp. 172-182
-
-
Honkakoski, P.1
Sueyoshi, T.2
Negishi, M.3
-
14
-
-
0025296345
-
Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450s
-
McManus ME, Burgess WM, Veronese ME, Huggett A, Quattrochi LC, Tuckey RH. 1990. Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450s. Cancer Res 50: 3367-3376.
-
(1990)
Cancer Res
, vol.50
, pp. 3367-3376
-
-
McManus, M.E.1
Burgess, W.M.2
Veronese, M.E.3
Huggett, A.4
Quattrochi, L.C.5
Tuckey, R.H.6
-
15
-
-
0034685779
-
Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands
-
Moore LM, Parks DJ, Jones SA et al. 2000. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands. J Biol Chem 275: 15122-15127.
-
(2000)
J Biol Chem
, vol.275
, pp. 15122-15127
-
-
Moore, L.M.1
Parks, D.J.2
Jones, S.A.3
-
16
-
-
33644777715
-
Traditional Chinese medicines Wu Wei Zi (Shisandra Chinesis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate PXR and increase warfarin clearance in rats
-
Mu Y, Zhang J, Zhang S et al. 2006. Traditional Chinese medicines Wu Wei Zi (Shisandra Chinesis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate PXR and increase warfarin clearance in rats. J Pharmacol Exp Ther 316: 1369-1377.
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 1369-1377
-
-
Mu, Y.1
Zhang, J.2
Zhang, S.3
-
17
-
-
2642510760
-
Role of the aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer
-
Nebert DW, Dalton TP, Okey AB, Gonzalez FJ. 2004. Role of the aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer. J Biol Chem 279: 23847-23850.
-
(2004)
J Biol Chem
, vol.279
, pp. 23847-23850
-
-
Nebert, D.W.1
Dalton, T.P.2
Okey, A.B.3
Gonzalez, F.J.4
-
18
-
-
0036581160
-
Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
-
Pfaffl MW, Horgan GW, Dempfle L. 2002. Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acid Res 30: (9) e36.
-
(2002)
Nucleic Acid Res
, vol.30
, Issue.9
-
-
Pfaffl, M.W.1
Horgan, G.W.2
Dempfle, L.3
-
19
-
-
0034639643
-
Indinavir concentrations and St. John's wort
-
Piscitelli SC, Burstein AH, Chaitt D, Alfaro RM, Fallon J. 2000. Indinavir concentrations and St. John's wort. Lancet 355: 547-548.
-
(2000)
Lancet
, vol.355
, pp. 547-548
-
-
Piscitelli, S.C.1
Burstein, A.H.2
Chaitt, D.3
Alfaro, R.M.4
Fallon, J.5
-
20
-
-
0037252475
-
Gene expression of CYP3A4, ABC- transporters (MDR1 and MRP1-5) and PXR in three different human colon carcinoma cell lines
-
Prufunder A, Gutmann H, Beglinger C, Drewe J. 2003. Gene expression of CYP3A4, ABC- transporters (MDR1 and MRP1-5) and PXR in three different human colon carcinoma cell lines. J Pharm Pharmacol 55: 59-66.
-
(2003)
J Pharm Pharmacol
, vol.55
, pp. 59-66
-
-
Prufunder, A.1
Gutmann, H.2
Beglinger, C.3
Drewe, J.4
-
21
-
-
1542328972
-
Properties of the reverse transcription reaction in mRNA quantification
-
Ståhlberg A, Håkansson J, Xian X, Semb H, Kubista M. 2004. Properties of the reverse transcription reaction in mRNA quantification. Clin Chem 50: 509-515.
-
(2004)
Clin Chem
, vol.50
, pp. 509-515
-
-
Ståhlberg, A.1
Håkansson, J.2
Xian, X.3
Semb, H.4
Kubista, M.5
-
22
-
-
2342619544
-
A human and mouse pregnane X receptor reporter gene assay in combination with cytotoxicity measurements as a tool to evaluate species-specific CYP3A induction
-
Vignati LA, Bogni A, Grossi P, Monshouwer M. 2004. A human and mouse pregnane X receptor reporter gene assay in combination with cytotoxicity measurements as a tool to evaluate species-specific CYP3A induction. Toxicology 199: 23-33.
-
(2004)
Toxicology
, vol.199
, pp. 23-33
-
-
Vignati, L.A.1
Bogni, A.2
Grossi, P.3
Monshouwer, M.4
-
23
-
-
0033541685
-
mRNA quantification by real time TaqMan polymerase chain reaction: Validation and comparison with RNase protection assay
-
Wang T, Brown MJ. 1999. mRNA quantification by real time TaqMan polymerase chain reaction: validation and comparison with RNase protection assay. Anal Biochem 269: 201.
-
(1999)
Anal Biochem
, vol.269
, pp. 201
-
-
Wang, T.1
Brown, M.J.2
-
25
-
-
0037286803
-
Interactions of herbs with cytochrome P450
-
Zhou S, Gao Y, Jiang W, Huang M, Xu A, Paxton JW. 2003. Interactions of herbs with cytochrome P450. Drug Metab Rev 35: 35-98.
-
(2003)
Drug Metab Rev
, vol.35
, pp. 35-98
-
-
Zhou, S.1
Gao, Y.2
Jiang, W.3
Huang, M.4
Xu, A.5
Paxton, J.W.6
|