Inhibitory effects of seven components of danshen extract on catalytic activity of cytochrome P450 enzyme in human liver microsomes

Drug Metabolism and Disposition

Volumn 36, Issue 7, 2008, Pages 1308-1314

  Qiu, Furong ^a,b   Zhang, Rong ^a   Sun, Jianguo ^a   Jiye, A ^a   Hao, Haiping ^a   Peng, Ying ^a   Ai, Hua ^a   Wang, Guangji ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b WANNAN MEDICAL COLLEGE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CRYPTOTANSHINONE; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; DEXTROMETHORPHAN; DICLOFENAC; MIDAZOLAM; PHENACETIN; PROTOCATECHUALDEHYDE; PROTOCATECHUIC ACID; SALVIA MILTIORRHIZA EXTRACT; SALVIANOLIC ACID B; TANSHINONE; TANSHINONE I; TANSHINONE IIA; TESTOSTERONE;

ARTICLE; CONTROLLED STUDY; DEMETHYLATION; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG STRUCTURE; ENZYME INHIBITION; HERB DRUG INTERACTION; HUMAN; HUMAN CELL; IC 50; LIVER MICROSOME; PRIORITY JOURNAL;

CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DRUGS, CHINESE HERBAL; HUMANS; KINETICS; MICROSOMES, LIVER;

EID: 46449109055     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.108.021030     Document Type: Article

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