-
1
-
-
0028207548
-
Stereoselective disposition of hexobarbital and its metabolites: Relationship to the S-mephenytoin polymorphism in Caucasian and Chinese subjects
-
A. Adedoyin C. Prakash D. O'shea I. A. Blair G. R. Wilkinson 1994 Stereoselective disposition of hexobarbital and its metabolites: relationship to the S-mephenytoin polymorphism in Caucasian and Chinese subjects Pharmacogenetics 4 27 38 8004130 1:CAS:528:DyaK2cXlt1Cnu70%3D (Pubitemid 24106121)
-
(1994)
Pharmacogenetics
, vol.4
, Issue.1
, pp. 27-38
-
-
Adedoyin, A.1
Prakash, C.2
O'Shea, D.3
Blair, I.A.4
Wilkinson, G.R.5
-
2
-
-
0028948839
-
A theoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability
-
7617530 1:CAS:528:DyaK2MXksVGqur8%3D
-
G. L. Amidon H. Lennernas V. P. Shah J. R. Crison 1995 A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability Pharm. Res. 12 413 420 7617530 1:CAS:528:DyaK2MXksVGqur8%3D
-
(1995)
Pharm. Res.
, vol.12
, pp. 413-420
-
-
Amidon, G.L.1
Lennernas, H.2
Shah, V.P.3
Crison, J.R.4
-
3
-
-
0034821939
-
Role of transport proteins in drug absorption, distribution and excretion
-
DOI 10.1080/00498250110060969
-
A. Ayrton P. Morgan 2001 Role of transport proteins in drug absorption, distribution and excretion Xenobiotica 31 469 497 11569523 1:CAS:528: DC%2BD3MXmvF2lt74%3D (Pubitemid 32826389)
-
(2001)
Xenobiotica
, vol.31
, Issue.8-9
, pp. 469-497
-
-
Ayrton, A.1
Morgan, P.2
-
4
-
-
67049114269
-
Methodology for development of a physiological model incorporating CYP3A and P-glycoprotein for the prediction of intestinal drug absorption
-
18855913 1:CAS:528:DC%2BD1MXltleltbc%3D
-
R. Badhan J. Penny A. Galetin J. B. Houston 2009 Methodology for development of a physiological model incorporating CYP3A and P-glycoprotein for the prediction of intestinal drug absorption J. Pharm. Sci. 98 2180 2197 18855913 1:CAS:528:DC%2BD1MXltleltbc%3D
-
(2009)
J. Pharm. Sci.
, vol.98
, pp. 2180-2197
-
-
Badhan, R.1
Penny, J.2
Galetin, A.3
Houston, J.B.4
-
5
-
-
0032825907
-
Population distribution and effects on drug metabolism of a genetic variant in the 5' promotor region of CYP3A4
-
DOI 10.1016/S0009-9236(99)70037-8
-
S. E. Ball J. Scatina J. Kao G. M. Ferron R. Fruncillo P. Mayer I. Weinryb M. Guida P. J. Hopkins N. Warner J. Hall 1999 Population distribution and effects on drug metabolism of a genetic variant in the 5' promoter region of CYP3A4 Clin. Pharmacol. Ther. 66 288 294 10511065 1:CAS:528:DyaK1MXmsFOjtLk%3D (Pubitemid 29451761)
-
(1999)
Clinical Pharmacology and Therapeutics
, vol.66
, Issue.3
, pp. 288-294
-
-
Ball, S.E.1
Scatina, J.2
Kao, J.3
Ferron, G.M.4
Fruncillo, R.5
Mayer, P.6
Weinryb, I.7
Guida, M.8
Hopkins, P.J.9
Warner, N.10
Hall, J.11
-
6
-
-
0038729506
-
CYP3A53 and 6 single nucleotide polymorphisms in three distinct Asian populations
-
C. Balram Q. Zhou Y. B. Cheung E. J. Lee 2003 CYP3A53 and 6 single nucleotide polymorphisms in three distinct Asian populations Eur. J. Clin. Pharmacol. 59 123 126 12756511 1:CAS:528:DC%2BD3sXksFGlu7k%3D (Pubitemid 36793724)
-
(2003)
European Journal of Clinical Pharmacology
, vol.59
, Issue.2
, pp. 123-126
-
-
Balram, C.1
Zhou, Q.2
Cheung, Y.B.3
Lee, E.J.D.4
-
7
-
-
0035478419
-
The drug efflux-metabolism alliance: Biochemical aspects
-
11576692 1:CAS:528:DC%2BD3MXntVWkurk%3D
-
L. Z. Benet C. L. Cummins 2001 The drug efflux-metabolism alliance: biochemical aspects Adv. Drug Deliv. Rev. 50 S3 S11 11576692 1:CAS:528:DC%2BD3MXntVWkurk%3D
-
(2001)
Adv. Drug Deliv. Rev.
, vol.50
-
-
Benet, L.Z.1
Cummins, C.L.2
-
8
-
-
77149165406
-
Predicting drug disposition via application of a Biopharmaceutics Drug Disposition Classification System
-
20002064 1:CAS:528:DC%2BC3cXivVShtLY%3D
-
L. Z. Benet 2010 Predicting drug disposition via application of a Biopharmaceutics Drug Disposition Classification System Basic Clin. Pharmacol. Toxicol. 106 162 167 20002064 1:CAS:528:DC%2BC3cXivVShtLY%3D
-
(2010)
Basic Clin. Pharmacol. Toxicol.
, vol.106
, pp. 162-167
-
-
Benet, L.Z.1
-
9
-
-
0026506140
-
Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin
-
1345344 1:CAS:528:DyaK38Xit1Olsbs%3D
-
L. Bertilsson Y. Q. Lou Y. L. Du Y. Liu T. Y. Kuang X. M. Liao K. Y. Wang J. Reviriego L. Iselius F. Sjoqvist 1992 Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin Clin. Pharmacol. Ther. 51 388 397 1345344 1:CAS:528:DyaK38Xit1Olsbs%3D
-
(1992)
Clin. Pharmacol. Ther.
, vol.51
, pp. 388-397
-
-
Bertilsson, L.1
Lou, Y.Q.2
Du, Y.L.3
Liu, Y.4
Kuang, T.Y.5
Liao, X.M.6
Wang, K.Y.7
Reviriego, J.8
Iselius, L.9
Sjoqvist, F.10
-
10
-
-
0035104031
-
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects
-
DOI 10.1067/mcp.2001.114164
-
I. Cascorbi T. Gerloff A. Johne C. Meisel S. Hoffmeyer M. Schwab E. Schaeffeler M. Eichelbaum U. Brinkmann I. Roots 2001 Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects Clin. Pharmacol. Ther. 69 169 174 11240981 1:CAS:528: DC%2BD3MXislylsb0%3D (Pubitemid 32225417)
-
(2001)
Clinical Pharmacology and Therapeutics
, vol.69
, Issue.3
, pp. 169-174
-
-
Cascorbi, I.1
Gerloff, T.2
Johne, A.3
Meisel, C.4
Hoffmeyer, S.5
Schwab, M.6
Schaeffeler, E.7
Eichelbaum, M.8
Brinkmann, U.9
Roots, I.10
-
11
-
-
0035659563
-
Bioavailability and bioequivalence: An FDA regulatory overview
-
DOI 10.1023/A:1013319408893
-
M. L. Chen V. Shah R. Patnaik W. Adams A. Hussain D. Conner M. Mehta H. Malinowski J. Lazor S. M. Huang D. Hare L. Lesko D. Sporn R. Williams 2001 Bioavailability and bioequivalence: an FDA regulatory overview Pharm. Res. 18 1645 1650 11785681 1:CAS:528:DC%2BD38XhvVagsA%3D%3D (Pubitemid 34020417)
-
(2001)
Pharmaceutical Research
, vol.18
, Issue.12
, pp. 1645-1650
-
-
Chen, M.-L.1
Shah, V.2
Patnaik, R.3
Adams, W.4
Hussain, A.5
Conner, D.6
Mehta, M.7
Malinowski, H.8
Lazor, J.9
Huang, S.-M.10
Hare, D.11
Lesko, L.12
Sporn, D.13
Williams, R.14
-
12
-
-
33645971659
-
Improvement and validation of an HPLC method for examining the effects of the MDR1 gene polymorphism on sparfloxacin pharmacokinetics
-
16530028 1:CAS:528:DC%2BD28XjsFOgtLw%3D
-
H. Y. Cho S. A. Park Y. B. Lee 2006 Improvement and validation of an HPLC method for examining the effects of the MDR1 gene polymorphism on sparfloxacin pharmacokinetics J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 834 84 92 16530028 1:CAS:528:DC%2BD28XjsFOgtLw%3D
-
(2006)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
, vol.834
, pp. 84-92
-
-
Cho, H.Y.1
Park, S.A.2
Lee, Y.B.3
-
13
-
-
74549218063
-
Pharmacokinetics and bioequivalence of two formulations of rebamipide 100-mg tablets: A randomized, single-dose, twoperiod, two-sequence crossover study in healthy Korean male volunteers
-
20110013 1:CAS:528:DC%2BC3cXhtFCjur8%3D
-
H. Y. Cho H. Yoon G. K. Park Y. B. Lee 2009 Pharmacokinetics and bioequivalence of two formulations of rebamipide 100-mg tablets: a randomized, single-dose, twoperiod, two-sequence crossover study in healthy Korean male volunteers Clin. Ther. 31 2712 2721 20110013 1:CAS:528:DC%2BC3cXhtFCjur8%3D
-
(2009)
Clin. Ther.
, vol.31
, pp. 2712-2721
-
-
Cho, H.Y.1
Yoon, H.2
Park, G.K.3
Lee, Y.B.4
-
14
-
-
77953812053
-
Influence of ABCB1 genetic polymorphisms on the pharmacokinetics of levosulpiride in healthy subjects
-
20438811 1:CAS:528:DC%2BC3cXnvVOms7s%3D
-
H. Y. Cho H. D. Yoo Y. B. Lee 2010 Influence of ABCB1 genetic polymorphisms on the pharmacokinetics of levosulpiride in healthy subjects Neuroscience 169 378 387 20438811 1:CAS:528:DC%2BC3cXnvVOms7s%3D
-
(2010)
Neuroscience
, vol.169
, pp. 378-387
-
-
Cho, H.Y.1
Yoo, H.D.2
Lee, Y.B.3
-
15
-
-
0037330517
-
Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients
-
DOI 10.1097/00008571-200302000-00005
-
B. Chowbay S. Cumaraswamy Y. B. Cheung Q. Zhou E. J. Lee 2003 Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients Pharmacogenetics 13 89 95 12563178 1:CAS:528:DC%2BD3sXot1Khug%3D%3D (Pubitemid 36259588)
-
(2003)
Pharmacogenetics
, vol.13
, Issue.2
, pp. 89-95
-
-
Chowbay, B.1
Cumaraswamy, S.2
Cheung, Y.B.3
Zhou, Q.4
Lee, E.J.D.5
-
16
-
-
0024544045
-
The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues
-
J. M. Croop M. Raymond D. Haber A. Devault R. J. Arceci P. Gros D. E. Housman 1989 The three mouse multidrug resistance (mdr) genes are expressed in a tissuespecific manner in normal mouse tissues Mol. Cell. Biol. 9 1346 1350 2471060 1:CAS:528:DyaL1MXhs1Ohu70%3D (Pubitemid 19071705)
-
(1989)
Molecular and Cellular Biology
, vol.9
, Issue.3
, pp. 1346-1350
-
-
Croop, J.M.1
Raymond, M.2
Haber, D.3
Devault, A.4
Arceci, R.J.5
Gros, P.6
Housman, D.E.7
-
17
-
-
0037328994
-
Pharmacogenetics of the major polymorphic metabolizing enzymes
-
DOI 10.1046/j.1472-8206.2003.00119.x
-
A. K. Daly 2003 Pharmacogenetics of the major polymorphic metabolizing enzymes Fundam. Clin. Pharmacol. 17 27 41 12588628 1:CAS:528: DC%2BD3sXhsFKlsb8%3D (Pubitemid 36241451)
-
(2003)
Fundamental and Clinical Pharmacology
, vol.17
, Issue.1
, pp. 27-41
-
-
Daly, A.K.1
-
18
-
-
79851476433
-
Interplay of metabolism and transport in determining oral drug absorption and gut wall metabolism: A simulation assessment using the "advanced Dissolution, Absorption, Metabolism (ADAM)" model
-
21189140 1:CAS:528:DC%2BC3MXhsl2kt7Y%3D
-
A. S. Darwich S. Neuhoff M. Jamei A. Rostami-Hodjegan 2010 Interplay of metabolism and transport in determining oral drug absorption and gut wall metabolism: a simulation assessment using the "Advanced Dissolution, Absorption, Metabolism (ADAM)" model Curr. Drug Metab. 11 716 729 21189140 1:CAS:528:DC%2BC3MXhsl2kt7Y%3D
-
(2010)
Curr. Drug Metab.
, vol.11
, pp. 716-729
-
-
Darwich, A.S.1
Neuhoff, S.2
Jamei, M.3
Rostami-Hodjegan, A.4
-
21
-
-
0025253133
-
Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities
-
1969610 1:CAS:528:DyaK3cXkslaitbk%3D
-
A. Devault P. Gros 1990 Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities Mol. Cell. Biol. 10 1652 1663 1969610 1:CAS:528:DyaK3cXkslaitbk%3D
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 1652-1663
-
-
Devault, A.1
Gros, P.2
-
22
-
-
0035135258
-
CDNA cloning and initial characterization of CYP3A43, a novel human cytochrome P450
-
T. L. Domanski C. Finta J. R. Halpert P. G. Zaphiropoulos 2001 cDNA cloning and initial characterization of CYP3A43, a novel human cytochrome P450 Mol. Pharmacol. 59 386 392 11160876 1:CAS:528:DC%2BD3MXnsl2gsQ%3D%3D (Pubitemid 32108573)
-
(2001)
Molecular Pharmacology
, vol.59
, Issue.2
, pp. 386-392
-
-
Domanski, T.L.1
Finta, C.2
Halpert, J.R.3
Zaphiropoulos, P.G.4
-
23
-
-
0035999902
-
MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine
-
DOI 10.1046/j.1365-2125.2002.01591.x
-
S. Drescher E. Schaeffeler M. Hitzl U. Hofmann M. Schwab U. Brinkmann M. Eichelbaum M. F. Fromm 2002 MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine Br. J. Clin. Pharmacol. 53 526 534 11994059 1:CAS:528:DC%2BD38Xks1Omsr0%3D (Pubitemid 34527155)
-
(2002)
British Journal of Clinical Pharmacology
, vol.53
, Issue.5
, pp. 526-534
-
-
Drescher, S.1
Schaeffeler, E.2
Hitzl, M.3
Hofmann, U.4
Schwab, M.5
Brinkmann, U.6
Eichelbaum, M.7
Fromm, M.F.8
-
24
-
-
0034959461
-
Identification and functional characterization of eight CYP3A4 protein variants
-
DOI 10.1097/00008571-200107000-00008
-
R. Eiselt T. L. Domanski A. Zibat R. Mueller E. Presecan-Siedel E. Hustert U. M. Zanger J. Brockmoller H. P. Klenk U. A. Meyer K. K. Khan Y. A. He J. R. Halpert L. Wojnowski 2001 Identification and functional characterization of eight CYP3A4 protein variants Pharmacogenetics 11 447 458 11470997 1:CAS:528:DC%2BD3MXlvVyntr8%3D (Pubitemid 32656585)
-
(2001)
Pharmacogenetics
, vol.11
, Issue.5
, pp. 447-458
-
-
Eiselt, R.1
Domanski, T.L.2
Zibat, A.3
Mueller, R.4
Presecan-Siedel, E.5
Hustert, E.6
Zanger, U.M.7
Brockmoller, J.8
Klenk, H.-P.9
Meyer, U.A.10
Khan, K.K.11
He, Y.-A.12
Halpert, J.R.13
Wojnowski, L.14
-
25
-
-
0037421590
-
Pharmacogenomics - Drug disposition, drug targets, and side effects
-
DOI 10.1056/NEJMra020526
-
W. E. Evans H. L. Mcleod 2003 Pharmacogenomics-drug disposition, drug targets, and side effects N. Engl. J. Med. 348 538 549 12571262 1:CAS:528:DC%2BD3sXovVKlsQ%3D%3D (Pubitemid 36159890)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.6
, pp. 538-549
-
-
Evans, W.E.1
McLeod, H.L.2
-
26
-
-
0037022006
-
Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: A pharmacogenetics study
-
DOI 10.1016/S0140-6736(02)07276-8
-
J. Fellay C. Marzolini E. R. Meaden D. J. Back T. Buclin J. P. Chave L. A. Decosterd H. Furrer M. Opravil G. Pantaleo D. Retelska L. Ruiz A. H. Schinkel P. Vernazza C. B. Eap A. Telenti 2002 Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study Lancet 359 30 36 11809184 1:CAS:528:DC%2BD38XmsV2mtw%3D%3D (Pubitemid 34119193)
-
(2002)
Lancet
, vol.359
, Issue.9300
, pp. 30-36
-
-
Fellay, J.1
Marzolini, C.2
Meaden, E.R.3
Back, D.J.4
Buclin, T.5
Chave, J.-P.6
Decosterd, L.A.7
Furrer, H.8
Opravil, M.9
Pantaleo, G.10
Retelska, D.11
Ruiz, L.12
Schinkel, A.H.13
Vernazza, P.14
Eap, C.B.15
Telenti, A.16
-
28
-
-
33747599176
-
Intestinal and hepatic metabolic activity of five cytochrome P450 enzymes: Impact on prediction of first-pass metabolism
-
DOI 10.1124/jpet.106.106013
-
A. Galetin J. B. Houston 2006 Intestinal and hepatic metabolic activity of five cytochrome P450 enzymes: impact on prediction of first-pass metabolism J. Pharmacol. Exp. Ther. 318 1220 1229 16763093 1:CAS:528:DC%2BD28XovFygt74%3D (Pubitemid 44268329)
-
(2006)
Journal of Pharmacology and Experimental Therapeutics
, vol.318
, Issue.3
, pp. 1220-1229
-
-
Galetin, A.1
Houston, J.B.2
-
29
-
-
0037026366
-
Correlation of tramadol pharmacokinetics and CYP2D610 genotype in Malaysian subjects
-
DOI 10.1016/S0731-7085(02)00214-5, PII S0731708502002145
-
S. H. Gan R. Ismail W. A. Wan Adnan Z. Wan 2002 Correlation of tramadol pharmacokinetics and CYP2D610 genotype in Malaysian subjects J. Pharm. Biomed. Anal. 30 189 195 12191703 1:CAS:528:DC%2BD38XmtlGqtro%3D (Pubitemid 35013483)
-
(2002)
Journal of Pharmaceutical and Biomedical Analysis
, vol.30
, Issue.2
, pp. 189-195
-
-
Gan, S.H.1
Ismail, R.2
Wan Adnan, W.A.3
Wan, Z.4
-
30
-
-
0742269421
-
Impact of genetic polymorphisms in transmembrane carrier-systems on drug and xenobiotic distribution
-
DOI 10.1007/s00210-003-0813-5
-
T. Gerloff 2004 Impact of genetic polymorphisms in transmembrane carrier-systems on drug and xenobiotic distribution Naunyn. Schmiedebergs Arch. Pharmacol. 369 69 77 14598019 1:CAS:528:DC%2BD2cXitF2hsg%3D%3D (Pubitemid 38161224)
-
(2004)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.369
, Issue.1
, pp. 69-77
-
-
Gerloff, T.1
-
31
-
-
0030904031
-
Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populations
-
DOI 10.1097/00008571-199702000-00008
-
J. A. Goldstein T. Ishizaki K. Chiba S. M. De Morais D. Bell P. M. Krahn D. A. Evans 1997 Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populations Pharmacogenetics 7 59 64 9110363 1:CAS:528:DyaK2sXislOkt74%3D (Pubitemid 27153320)
-
(1997)
Pharmacogenetics
, vol.7
, Issue.1
, pp. 59-64
-
-
Goldstein, J.A.1
Ishizaki, T.2
Chiba, K.3
De Morais, S.M.F.4
Bell, D.5
Krahn, P.M.6
Price Evans, D.A.7
-
32
-
-
0036667953
-
C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation
-
DOI 10.1097/00008571-200208000-00005
-
M. Goto S. Masuda H. Saito S. Uemoto T. Kiuchi K. Tanaka K. Inui 2002 C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation Pharmacogenetics 12 451 457 12172213 1:CAS:528:DC%2BD38Xmslejt7c%3D (Pubitemid 34913527)
-
(2002)
Pharmacogenetics
, vol.12
, Issue.6
, pp. 451-457
-
-
Goto, M.1
Masuda, S.2
Saito, H.3
Uemoto, S.4
Kiuchi, T.5
Tanaka, K.6
Inui, K.-I.7
-
33
-
-
12144286933
-
The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients
-
DOI 10.1097/00008571-200403000-00002
-
V. Haufroid M. Mourad V. Van Kerckhove J. Wawrzyniak M. De Meyer D. C. Eddour J. Malaise D. Lison J. P. Squifflet P. Wallemacq 2004 The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients Pharmacogenetics 14 147 154 15167702 1:CAS:528:DC%2BD2cXjt1Kjsrs%3D (Pubitemid 38373108)
-
(2004)
Pharmacogenetics
, vol.14
, Issue.3
, pp. 147-154
-
-
Haufroid, V.1
Mourad, M.2
Van Kerckhove, V.3
Wawrzyniak, J.4
De Meyer, M.5
Eddour, D.C.6
Malaise, J.7
Lison, D.8
Squifflet, J.-P.9
Wallemacq, P.10
-
34
-
-
10044294681
-
Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes
-
DOI 10.1016/j.clpt.2004.08.022, PII S0009923604002930
-
D. A. Hesselink T. Van Gelder R. H. Van Schaik A. H. Balk I. P. Van Der Heiden T. Van Dam M. Van Der Werf W. Weimar R. A. Mathot 2004 Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes Clin. Pharmacol. Ther. 76 545 556 15592326 1:CAS:528: DC%2BD2cXhtVKlt7rL (Pubitemid 39601545)
-
(2004)
Clinical Pharmacology and Therapeutics
, vol.76
, Issue.6
, pp. 545-556
-
-
Hesselink, D.A.1
Van Gelder, T.2
Van Schaik, R.H.N.3
Balk, A.H.M.M.4
Van Der Heiden, I.P.5
Van Dam, T.6
Van Der Werf, M.7
Weimar, W.8
Mathot, R.A.A.9
-
35
-
-
70349091471
-
Genetic variation in the proximal promoter of ABC and SLC superfamilies: Liver and kidney specific expression and promoter activity predict variation
-
19742321
-
S. E. Hesselson P. Matsson J. E. Shima H. Fukushima S. W. Yee Y. Kobayashi J. M. Gow C. Ha B. Ma A. Poon S. J. Johns D. Stryke R. A. Castro H. Tahara J. H. Choi L. Chen N. Picard E. Sjodin M. J. Roelofs T. E. Ferrin R. Myers D. L. Kroetz P. Y. Kwok K. M. Giacomini 2009 Genetic variation in the proximal promoter of ABC and SLC superfamilies: liver and kidney specific expression and promoter activity predict variation PloS One 4 e6942 19742321
-
(2009)
PloS One
, vol.4
, pp. 6942
-
-
Hesselson, S.E.1
Matsson, P.2
Shima, J.E.3
Fukushima, H.4
Yee, S.W.5
Kobayashi, Y.6
Gow, J.M.7
Ha, C.8
Ma, B.9
Poon, A.10
Johns, S.J.11
Stryke, D.12
Castro, R.A.13
Tahara, H.14
Choi, J.H.15
Chen, L.16
Picard, N.17
Sjodin, E.18
Roelofs, M.J.19
Ferrin, T.E.20
Myers, R.21
Kroetz, D.L.22
Kwok, P.Y.23
Giacomini, K.M.24
more..
-
36
-
-
0026621245
-
ABC Transporters: From microorganisms to man
-
C. F. Higgins 1992 ABC transporters: from microorganisms to man Annu. Rev. Cell Biol. 8 67 113 1282354 1:CAS:528:DyaK3sXhvVSmuw%3D%3D (Pubitemid 23000992)
-
(1992)
Annual Review of Cell Biology
, vol.8
, pp. 67-113
-
-
Higgins, C.F.1
-
37
-
-
0034971274
-
+ natural killer cells
-
DOI 10.1097/00008571-200106000-00003
-
M. Hitzl S. Drescher H. Van Der Kuip E. Schaffeler J. Fischer M. Schwab M. Eichelbaum M. F. Fromm 2001 The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells Pharmacogenetics 11 293 298 11434506 1:CAS:528:DC%2BD3MXkvFeis74%3D (Pubitemid 32537402)
-
(2001)
Pharmacogenetics
, vol.11
, Issue.4
, pp. 293-298
-
-
Hitzl, M.1
Drescher, S.2
Van Der Kuip, H.3
Schaffeler, E.4
Fischer, J.5
Schwab, M.6
Eichelbaum, M.7
Fromm, M.F.8
-
38
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P- glycoprotein expression and activity in vivo
-
DOI 10.1073/pnas.050585397
-
S. Hoffmeyer O. Burk O. Von Richter H. P. Arnold J. Brockmoller A. Johne I. Cascorbi T. Gerloff I. Roots M. Eichelbaum U. Brinkmann 2000 Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with Pglycoprotein expression and activity in vivo Proc. Natl. Acad. Sci. U. S. A. 97 3473 3478 10716719 1:CAS:528:DC%2BD3cXitlWqtL8%3D (Pubitemid 30183327)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.7
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
Arnold, H.P.4
Brockmoller, J.5
Johne, A.6
Cascorbi, I.7
Gerloff, T.8
Roots, I.9
Eichelbaum, M.10
Brinkmann, U.11
-
39
-
-
0024344261
-
Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes
-
S. I. Hsu L. Lothstein S. B. Horwitz 1989 Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes J. Biol. Chem. 264 12053 12062 2473069 1:CAS:528:DyaL1MXkvFWmur8%3D (Pubitemid 19185382)
-
(1989)
Journal of Biological Chemistry
, vol.264
, Issue.20
, pp. 12053-12062
-
-
Hsu, S.I.-H.1
Lothstein, L.2
Horwitz, S.B.3
-
40
-
-
0035217180
-
The genetic determinants of the CYP3A5 polymorphism
-
DOI 10.1097/00008571-200112000-00005
-
E. Hustert M. Haberl O. Burk R. Wolbold Y. Q. He K. Klein A. C. Nuessler P. Neuhaus J. Klattig R. Eiselt I. Koch A. Zibat J. Brockmoller J. R. Halpert U. M. Zanger L. Wojnowski 2001 The genetic determinants of the CYP3A5 polymorphism Pharmacogenetics 11 773 779 11740341 1:CAS:528:DC%2BD38XnsFKqsrk%3D (Pubitemid 33151512)
-
(2001)
Pharmacogenetics
, vol.11
, Issue.9
, pp. 773-779
-
-
Hustert, E.1
Haberl, M.2
Burk, O.3
Wolbold, R.4
He, Y.-Q.5
Klein, K.6
Nuessler, A.C.7
Neuhaus, P.8
Klattig, J.9
Eiselt, R.10
Koch, I.11
Zibat, A.12
Brockmoller, J.13
Halpert, J.R.14
Zanger, U.M.15
Wojnowski, L.16
-
41
-
-
0027965620
-
Genetic analysis of the Chinese cytochrome P4502D locus: Characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation
-
I. Johansson M. Oscarson Q. Y. Yue L. Bertilsson F. Sjoqvist M. Ingelman-Sundberg 1994 Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation Mol. Pharmacol. 46 452 459 7935325 1:CAS:528:DyaK2MXhtFeis7w%3D (Pubitemid 24296678)
-
(1994)
Molecular Pharmacology
, vol.46
, Issue.3
, pp. 452-459
-
-
Johansson, I.1
Oscarson, M.2
Yue, Q.-Y.3
Bertilsson, L.4
Sjoqvist, F.5
Ingelman-Sundberg, M.6
-
42
-
-
0036881149
-
Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene
-
DOI 10.1067/mcp.2002.129196
-
A. Johne K. Kopke T. Gerloff I. Mai S. Rietbrock C. Meisel S. Hoffmeyer R. Kerb M. F. Fromm U. Brinkmann M. Eichelbaum J. Brockmoller I. Cascorbi I. Roots 2002 Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene Clin. Pharmacol. Ther. 72 584 594 12426522 1:CAS:528:DC%2BD38XpsFSisbg%3D (Pubitemid 36237730)
-
(2002)
Clinical Pharmacology and Therapeutics
, vol.72
, Issue.5
, pp. 584-594
-
-
Johne, A.1
Kopke, K.2
Gerloff, T.3
Mai, I.4
Rietbrock, S.5
Meisel, C.6
Hoffmeyer, S.7
Kerb, R.8
Fromm, M.F.9
Brinkmann, U.10
Eichelbaum, M.11
Brockmoller, J.12
Cascorbi, I.13
Roots, I.14
-
43
-
-
0041856526
-
Application of compartmental modeling to an examination of in vitro intestinal permeability data: Assessing the impact of tissue uptake, P-glycoprotein, and CYP3A
-
DOI 10.1124/dmd.31.9.1151
-
B. M. Johnson W. N. Charman C. J. Porter 2003 Application of compartmental modeling to an examination of in vitro intestinal permeability data: assessing the impact of tissue uptake, P-glycoprotein, and CYP3A Drug Metab. Dispos. 31 1151 1160 12920171 1:CAS:528:DC%2BD3sXmslKlu70%3D (Pubitemid 37048287)
-
(2003)
Drug Metabolism and Disposition
, vol.31
, Issue.9
, pp. 1151-1160
-
-
Johnson, B.M.1
Charman, W.N.2
Porter, C.J.H.3
-
44
-
-
33644781452
-
Implications of genetic polymorphisms in drug transporters for pharmacotherapy
-
DOI 10.1016/j.canlet.2005.06.051, PII S0304383505009225, Pharmacogenomics in Cancer Chemotherapy: Recent Advances in Drug Transporters and Genome Analysis
-
R. Kerb 2006 Implications of genetic polymorphisms in drug transporters for pharmacotherapy Cancer Lett. 234 4 33 16504381 1:CAS:528: DC%2BD28Xit12itL8%3D (Pubitemid 43343938)
-
(2006)
Cancer Letters
, vol.234
, Issue.1
, pp. 4-33
-
-
Kerb, R.1
-
45
-
-
45249088224
-
The effect of CYP2C19 polymorphism on the pharmacokinetics and pharmacodynamics of clopidogrel: A possible mechanism for clopidogrel resistance
-
18323861 1:CAS:528:DC%2BD1cXptlyktLc%3D
-
K. A. Kim P. W. Park S. J. Hong J. Y. Park 2008 The effect of CYP2C19 polymorphism on the pharmacokinetics and pharmacodynamics of clopidogrel: a possible mechanism for clopidogrel resistance Clin. Pharmacol. Ther. 84 236 242 18323861 1:CAS:528:DC%2BD1cXptlyktLc%3D
-
(2008)
Clin. Pharmacol. Ther.
, vol.84
, pp. 236-242
-
-
Kim, K.A.1
Park, P.W.2
Hong, S.J.3
Park, J.Y.4
-
46
-
-
3042772026
-
Identification of functionally variant MDR1 alleles among European Americans and African Americans
-
DOI 10.1067/mcp.2001.117412
-
R. B. Kim B. F. Leake E. F. Choo G. K. Dresser S. V. Kubba U. I. Schwarz A. Taylor H. G. Xie J. Mckinsey S. Zhou L. B. Lan J. D. Schuetz E. G. Schuetz G. R. Wilkinson 2001 Identification of functionally variant MDR1 alleles among European Americans and African Americans Clin. Pharmacol. Ther. 70 189 199 11503014 1:CAS:528:DC%2BD3MXmslygs7o%3D (Pubitemid 32777772)
-
(2001)
Clinical Pharmacology and Therapeutics
, vol.70
, Issue.2
, pp. 189-199
-
-
Kim, R.B.1
Leake, B.F.2
Choo, E.F.3
Dresser, G.K.4
Kubba, S.V.5
Schwarz, U.I.6
Taylor, A.7
Xie, H.-G.8
McKinsey, J.9
Zhou, S.10
Lan, L.-B.11
Schuetz, J.D.12
Schuetz, E.G.13
Wilkinson, G.R.14
-
47
-
-
0036667955
-
MDR1 single nucleotide polymorphisms: Multiplicity of haplotypes and functional consequences
-
DOI 10.1097/00008571-200208000-00002
-
R. B. Kim 2002 MDR1 single nucleotide polymorphisms: multiplicity of haplotypes and functional consequences Pharmacogenetics 12 425 427 12172210 1:CAS:528:DC%2BD38Xmslejt78%3D (Pubitemid 34913525)
-
(2002)
Pharmacogenetics
, vol.12
, Issue.6
, pp. 425-427
-
-
Kim, R.B.1
-
48
-
-
17644445622
-
Transporters and xenobiotic disposition
-
DOI 10.1016/S0300-483X(02)00296-2, PII S0300483X02002962
-
R. B. Kim 2002 Transporters and xenobiotic disposition Toxicology 181-182 291 297 12505328 (Pubitemid 36015716)
-
(2002)
Toxicology
, vol.181-182
, pp. 291-297
-
-
Kim, R.B.1
-
49
-
-
0036082545
-
Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system
-
DOI 10.1124/mol.62.1.1
-
C. Kimchi-Sarfaty J. J. Gribar M. M. Gottesman 2002 Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system Mol. Pharmacol. 62 1 6 12065748 1:CAS:528: DC%2BD38Xlt1KqtLw%3D (Pubitemid 34680509)
-
(2002)
Molecular Pharmacology
, vol.62
, Issue.1
, pp. 1-6
-
-
Kimchi-Sarfaty, C.1
Gribar, J.J.2
Gottesman, M.M.3
-
50
-
-
33846504706
-
A "silent" polymorphism in the MDR1 gene changes substrate specificity
-
DOI 10.1126/science.1135308
-
C. Kimchi-Sarfaty J. M. Oh I. W. Kim Z. E. Sauna A. M. Calcagno S. V. Ambudkar M. M. Gottesman 2007 A "silent" polymorphism in the MDR1 gene changes substrate specificity Science 315 525 528 17185560 1:CAS:528: DC%2BD2sXotFCitA%3D%3D (Pubitemid 46175758)
-
(2007)
Science
, vol.315
, Issue.5811
, pp. 525-528
-
-
Kimchi-Sarfaty, C.1
Oh, J.M.2
Kim, I.-W.3
Sauna, Z.E.4
Calcagno, A.M.5
Ambudkar, S.V.6
Gottesman, M.M.7
-
51
-
-
39149124458
-
Pharmacodynamic consequences of P-glycoprotein-dependent pharmacokinetics of risperidone and haloperidol in mice
-
18164477 1:CAS:528:DC%2BD1cXhslOjtbs%3D
-
K. M. Kirschbaum S. Henken C. Hiemke U. Schmitt 2008 Pharmacodynamic consequences of P-glycoprotein-dependent pharmacokinetics of risperidone and haloperidol in mice Behav. Brain Res. 188 298 303 18164477 1:CAS:528: DC%2BD1cXhslOjtbs%3D
-
(2008)
Behav. Brain Res.
, vol.188
, pp. 298-303
-
-
Kirschbaum, K.M.1
Henken, S.2
Hiemke, C.3
Schmitt, U.4
-
52
-
-
4143049054
-
Lipid-lowering response to statins is affected by CYP3A5 polymorphism
-
DOI 10.1097/01.fpc.0000114762.78957.a5
-
K. T. Kivisto M. Niemi E. Schaeffeler K. Pitkala R. Tilvis M. F. Fromm M. Schwab M. Eichelbaum T. Strandberg 2004 Lipid-lowering response to statins is affected by CYP3A5 polymorphism Pharmacogenetics 14 523 525 15284534 (Pubitemid 39100004)
-
(2004)
Pharmacogenetics
, vol.14
, Issue.8
, pp. 523-525
-
-
Kivisto, K.T.1
Niemi, M.2
Schaeffeler, E.3
Pitkala, K.4
Tilvis, R.5
Fromm, M.F.6
Schwab, M.7
Eichelbaum, M.8
Strandberg, T.9
-
53
-
-
33745914612
-
Clinical impact of CYP2C19 polymorphism on the action of proton pump inhibitors: A review of a special problem
-
U. Klotz 2006 Clinical impact of CYP2C19 polymorphism on the action of proton pump inhibitors: a review of a special problem Int. J. Clin. Pharmacol. Ther. 44 297 302 16961157 1:CAS:528:DC%2BD28XovF2gtLc%3D (Pubitemid 44043771)
-
(2006)
International Journal of Clinical Pharmacology and Therapeutics
, vol.44
, Issue.7
, pp. 297-302
-
-
Klotz, U.1
-
54
-
-
10744222684
-
Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene
-
DOI 10.1097/00008571-200308000-00006
-
D. L. Kroetz C. Pauli-Magnus L. M. Hodges C. C. Huang M. Kawamoto S. J. Johns D. Stryke T. E. Ferrin J. Deyoung T. Taylor E. J. Carlson I. Herskowitz K. M. Giacomini A. G. Clark 2003 Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene Pharmacogenetics 13 481 494 12893986 1:CAS:528:DC%2BD3sXlvV2jt7Y%3D (Pubitemid 37034590)
-
(2003)
Pharmacogenetics
, vol.13
, Issue.8
, pp. 481-494
-
-
Kroetz, D.L.1
Pauli-Magnus, C.2
Hodges, L.M.3
Huang, C.C.4
Kawamoto, M.5
Johns, S.J.6
Stryke, D.7
Ferrin, T.E.8
DeYoung, J.9
Taylor, T.10
Carlson, E.J.11
Herskowitz, I.12
Giacomini, K.M.13
Clark, A.G.14
-
55
-
-
0035071598
-
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
-
DOI 10.1038/86882
-
P. Kuehl J. Zhang Y. Lin J. Lamba M. Assem J. Schuetz P. B. Watkins A. Daly S. A. Wrighton S. D. Hall P. Maurel M. Relling C. Brimer K. Yasuda R. Venkataramanan S. Strom K. Thummel M. S. Boguski E. Schuetz 2001 Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression Nat. Genet. 27 383 391 11279519 1:CAS:528:DC%2BD3MXjtFShs7k%3D (Pubitemid 32268418)
-
(2001)
Nature Genetics
, vol.27
, Issue.4
, pp. 383-391
-
-
Kuehl, P.1
Zhang, J.2
Lin, Y.3
Lamba, J.4
Assem, M.5
Schuetz, J.6
Watkins, P.B.7
Daly, A.8
Wrighton, S.A.9
Hall, S.D.10
Maurel, P.11
Relling, M.12
Brimer, C.13
Yasuda, K.14
Venkataramanan, R.15
Strom, S.16
Thummel, K.17
Boguski, M.S.18
Schuetz, E.19
-
56
-
-
53549126614
-
Effects of CYP3A5 and MDR1 single nucleotide polymorphisms on drug interactions between tacrolimus and fluconazole in renal allograft recipients
-
18704002 1:CAS:528:DC%2BD1cXhtFartbjP
-
D. R. Kuypers H. De Jonge M. Naesens Y. Vanrenterghem 2008 Effects of CYP3A5 and MDR1 single nucleotide polymorphisms on drug interactions between tacrolimus and fluconazole in renal allograft recipients Pharmacogenet. Genomics 18 861 868 18704002 1:CAS:528:DC%2BD1cXhtFartbjP
-
(2008)
Pharmacogenet. Genomics
, vol.18
, pp. 861-868
-
-
Kuypers, D.R.1
De Jonge, H.2
Naesens, M.3
Vanrenterghem, Y.4
-
57
-
-
0032540001
-
HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter
-
DOI 10.1021/bi972709x
-
C. G. Lee M. M. Gottesman C. O. Cardarelli M. Ramachandra K. T. Jeang S. V. Ambudkar I. Pastan S. Dey 1998 HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter Biochemistry (Mosc.) 37 3594 3601 1:CAS:528:DyaK1cXht12ltL4%3D (Pubitemid 28162914)
-
(1998)
Biochemistry
, vol.37
, Issue.11
, pp. 3594-3601
-
-
Lee, C.G.L.1
Gottesman, M.M.2
Cardarelli, C.O.3
Ramachandra, M.4
Jeang, K.-T.5
Ambudkar, S.V.6
Pastan, I.7
Dey, S.8
-
58
-
-
0041881985
-
Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups
-
DOI 10.1097/00008571-200308000-00004
-
S. J. Lee K. A. Usmani B. Chanas B. Ghanayem T. Xi E. Hodgson H. W. Mohrenweiser J. A. Goldstein 2003 Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups Pharmacogenetics 13 461 472 12893984 1:CAS:528:DC%2BD3sXlvV2jt7g%3D (Pubitemid 37034588)
-
(2003)
Pharmacogenetics
, vol.13
, Issue.8
, pp. 461-472
-
-
Lee, S.-J.1
Usmani, K.A.2
Chanas, B.3
Ghanayem, B.4
Xi, T.5
Hodgson, E.6
Mohrenweiser, H.W.7
Goldstein, J.A.8
-
59
-
-
0033801280
-
Membrane transporters
-
V. H. Lee 2000 Membrane transporters Eur. J. Pharm. Sci. 11 41 50
-
(2000)
Eur. J. Pharm. Sci.
, vol.11
, pp. 41-50
-
-
Lee, V.H.1
-
60
-
-
27144556111
-
Effect of common CYP3A4 and CYP3A5 variants on the pharmacokinetics of the cytochrome P450 3A phenotyping probe midazolam in cancer patients
-
DOI 10.1158/1078-0432.CCR-05-0520
-
E. R. Lepper S. D. Baker M. Permenter N. Ries R. H. Van Schaik P. W. Schenk D. K. Price D. Ahn N. F. Smith G. Cusatis R. G. Ingersoll S. E. Bates R. H. Mathijssen J. Verweij W. D. Figg A. Sparreboom 2005 Effect of common CYP3A4 and CYP3A5 variants on the pharmacokinetics of the cytochrome P450 3A phenotyping probe midazolam in cancer patients Clin. Cancer Res. 11 7398 7404 16243813 1:CAS:528:DC%2BD2MXhtFartbvM (Pubitemid 41507700)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.20
, pp. 7398-7404
-
-
Lepper, E.R.1
Baker, S.D.2
Permenter, M.3
Ries, N.4
Van Schaik, R.H.N.5
Schenk, P.W.6
Price, D.K.7
Ahn, D.8
Smith, N.F.9
Cusatis, G.10
Ingersoll, R.G.11
Bates, S.E.12
Mathijssen, R.H.J.13
Verweij, J.14
Figg, W.D.15
Sparreboom, A.16
-
61
-
-
17544368685
-
Multidrug resistance proteins: Role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
-
DOI 10.1016/j.taap.2004.10.012, Membrane Transporters in Toxicology
-
E. M. Leslie R. G. Deeley S. P. Cole 2005 Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense Toxicol. Appl. Pharmacol. 204 216 237 15845415 1:CAS:528:DC%2BD2MXjsFGqtrY%3D (Pubitemid 40552845)
-
(2005)
Toxicology and Applied Pharmacology
, vol.204
, Issue.3
, pp. 216-237
-
-
Leslie, E.M.1
Deeley, R.G.2
Cole, S.P.C.3
-
62
-
-
10044225576
-
Lower frequency of CYP2C92 in Mexican-Americans compared to Spaniards
-
DOI 10.1038/sj.tpj.6500278
-
A. Llerena P. Dorado F. O'kirwan R. Jepson J. Licinio M. L. Wong 2004 Lower frequency of CYP2C92 in Mexican-Americans compared to Spaniards Pharmacogenomics J. 4 403 406 15452553 1:CAS:528:DC%2BD2cXpvV2rurY%3D (Pubitemid 39600058)
-
(2004)
Pharmacogenomics Journal
, vol.4
, Issue.6
, pp. 403-406
-
-
Llerena, A.1
Dorado, P.2
O'Kirwan, F.3
Jepson, R.4
Licinio, J.5
Wong, M.-L.6
-
63
-
-
0037115210
-
Tacrolimus pharmacogenetics: Polymorphisms associated with expression of cytochrome P4503a5 and P-glycoprotein correlate with dose requirement
-
DOI 10.1097/00007890-200212150-00002
-
I. A. Macphee S. Fredericks T. Tai P. Syrris N. D. Carter A. Johnston L. Goldberg D. W. Holt 2002 Tacrolimus pharmacogenetics: polymorphisms associated with expression of cytochrome p4503A5 and P-glycoprotein correlate with dose requirement Transplantation 74 1486 1489 12490779 1:CAS:528:DC%2BD38Xps1Wgt7g%3D (Pubitemid 36014218)
-
(2002)
Transplantation
, vol.74
, Issue.11
, pp. 1486-1489
-
-
Macphee, I.A.M.1
Fredericks, S.2
Tai, T.3
Syrris, P.4
Carter, N.D.5
Johnston, A.6
Goldberg, L.7
Holt, D.W.8
-
64
-
-
14044278166
-
Tacrolimus pharmacogenetics: The CYP3A51 allele predicts low dose-normalized tacrolimus blood concentrations in whites and south Asians
-
DOI 10.1097/01.TP.0000151766.73249.12
-
I. A. Macphee S. Fredericks M. Mohamed M. Moreton N. D. Carter A. Johnston L. Goldberg D. W. Holt 2005 Tacrolimus pharmacogenetics: the CYP3A51 allele predicts low dose-normalized tacrolimus blood concentrations in whites and South Asians Transplantation 79 499 502 15729180 1:CAS:528: DC%2BD2MXhsF2lt7Y%3D (Pubitemid 40280186)
-
(2005)
Transplantation
, vol.79
, Issue.4
, pp. 499-502
-
-
MacPhee, I.A.M.1
Fredericks, S.2
Mohamed, M.3
Moreton, M.4
Carter, N.D.5
Johnston, A.6
Goldberg, L.7
Holt, D.W.8
-
65
-
-
56149110125
-
Impact of genetic polymorphisms of transporters on the pharmacokinetic, pharmacodynamic and toxicological properties of anionic drugs
-
18762709 1:CAS:528:DC%2BD1cXht12itL3P
-
K. Maeda Y. Sugiyama 2008 Impact of genetic polymorphisms of transporters on the pharmacokinetic, pharmacodynamic and toxicological properties of anionic drugs Drug Metab. Pharmacokinet. 23 223 235 18762709 1:CAS:528: DC%2BD1cXht12itL3P
-
(2008)
Drug Metab. Pharmacokinet.
, vol.23
, pp. 223-235
-
-
Maeda, K.1
Sugiyama, Y.2
-
66
-
-
9144253194
-
MDR1 haplotypes derived from exons 21 and 26 do not affect the steady-state pharmacokinetics of tacrolimus in renal transplant patients
-
DOI 10.1111/j.1365-2125.2004.02182.x
-
I. Mai E. S. Perloff S. Bauer M. Goldammer A. Johne G. Filler K. Budde I. Roots 2004 MDR1 haplotypes derived from exons 21 and 26 do not affect the steadystate pharmacokinetics of tacrolimus in renal transplant patients Br. J. Clin. Pharmacol. 58 548 553 15521904 1:CAS:528:DC%2BD2cXhtFahur7K (Pubitemid 39540460)
-
(2004)
British Journal of Clinical Pharmacology
, vol.58
, Issue.5
, pp. 548-553
-
-
Mai, I.1
Perloff, E.S.2
Bauer, S.3
Goldammer, M.4
Johne, A.5
Filler, G.6
Budde, K.7
Roots, I.8
-
67
-
-
1642523162
-
Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance
-
DOI 10.1016/j.clpt.2003.09.012
-
C. Marzolini E. Paus T. Buclin R. B. Kim 2004 Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance Clin. Pharmacol. Ther. 75 13 33 14749689 1:CAS:528:DC%2BD2cXntVKiuw%3D%3D (Pubitemid 38130115)
-
(2004)
Clinical Pharmacology and Therapeutics
, vol.75
, Issue.1
, pp. 13-33
-
-
Marzolini, C.1
Paus, E.2
Buclin, T.3
Kim, R.B.4
-
68
-
-
4344574336
-
Pharmacogenetics - Five decades of therapeutic lessons from genetic diversity
-
DOI 10.1038/nrg1428
-
U. A. Meyer 2004 Pharmacogenetics - five decades of therapeutic lessons from genetic diversity Nat. Rev. Genet. 5 669 676 15372089 1:CAS:528: DC%2BD2cXnt12nt78%3D (Pubitemid 39150124)
-
(2004)
Nature Reviews Genetics
, vol.5
, Issue.9
, pp. 669-676
-
-
Meyer, U.A.1
-
69
-
-
0036001238
-
C3435T mutation in exon 26 of the human MDR1 gene and cyclosporine pharmacokinetics in healthy subjects
-
DOI 10.1097/00007691-200206000-00012
-
D. I. Min V. L. Ellingrod 2002 C3435T mutation in exon 26 of the human MDR1 gene and cyclosporine pharmacokinetics in healthy subjects Ther. Drug Monit. 24 400 404 12021632 1:CAS:528:DC%2BD38Xks1Gnu7c%3D (Pubitemid 34553206)
-
(2002)
Therapeutic Drug Monitoring
, vol.24
, Issue.3
, pp. 400-404
-
-
Min, D.I.1
Ellingrod, V.L.2
-
70
-
-
0037766006
-
Association of the CYP3A41B 5′-flanking region polymorphism with cyclosporine pharmacokinetics in healthy subjects
-
DOI 10.1097/00007691-200306000-00010
-
D. I. Min V. L. Ellingrod 2003 Association of the CYP3A41B 5'-flanking region polymorphism with cyclosporine pharmacokinetics in healthy subjects Ther. Drug Monit. 25 305 309 12766558 1:CAS:528:DC%2BD3sXktlyrsrw%3D (Pubitemid 36638175)
-
(2003)
Therapeutic Drug Monitoring
, vol.25
, Issue.3
, pp. 305-309
-
-
Min, D.I.1
Ellingrod, V.L.2
-
71
-
-
0031841377
-
Cytochrome P4502C9: An enzyme of major importance in human drug metabolism
-
DOI 10.1046/j.1365-2125.1998.00721.x
-
J. O. Miners D. J. Birkett 1998 Cytochrome P4502C9: an enzyme of major importance in human drug metabolism Br. J. Clin. Pharmacol. 45 525 538 9663807 1:CAS:528:DyaK1cXktFaitro%3D (Pubitemid 28270907)
-
(1998)
British Journal of Clinical Pharmacology
, vol.45
, Issue.6
, pp. 525-538
-
-
Miners, J.O.1
Birkett, D.J.2
-
72
-
-
0038323843
-
Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities
-
DOI 10.1016/S0006-2952(03)00178-3
-
N. Morita T. Yasumori K. Nakayama 2003 Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities Biochem. Pharmacol. 65 1843 1852 12781336 1:CAS:528:DC%2BD3sXktVOrsL0%3D (Pubitemid 36629509)
-
(2003)
Biochemical Pharmacology
, vol.65
, Issue.11
, pp. 1843-1852
-
-
Morita, N.1
Yasumori, T.2
Nakayama, K.3
-
73
-
-
28844459455
-
Variation in oral clearance of saquinavir is predicted by CYP3A51 genotype but not by enterocyte content of cytochrome P450 3A5
-
DOI 10.1016/j.clpt.2005.08.014, PII S0009923605003632
-
S. J. Mouly C. Matheny M. F. Paine G. Smith J. Lamba V. Lamba S. N. Pusek E. G. Schuetz P. W. Stewart P. B. Watkins 2005 Variation in oral clearance of saquinavir is predicted by CYP3A51 genotype but not by enterocyte content of cytochrome P450 3A5 Clin. Pharmacol. Ther. 78 605 618 16338276 1:CAS:528:DC%2BD2MXhtlShsLnI (Pubitemid 41773636)
-
(2005)
Clinical Pharmacology and Therapeutics
, vol.78
, Issue.6
, pp. 605-618
-
-
Mouly, S.J.1
Matheny, C.2
Paine, M.F.3
Smith, G.4
Lamba, J.5
Lamba, V.6
Pusek, S.N.7
Schuetz, E.G.8
Stewart, P.W.9
Watkins, P.B.10
-
74
-
-
0036224114
-
Effect of the mutation (C3435t) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects
-
DOI 10.1067/mcp.2002.122055
-
T. Nakamura T. Sakaeda M. Horinouchi T. Tamura N. Aoyama T. Shirakawa M. Matsuo M. Kasuga K. Okumura 2002 Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects Clin. Pharmacol. Ther. 71 297 303 11956513 1:CAS:528:DC%2BD38Xjs1ertrw%3D (Pubitemid 34311459)
-
(2002)
Clinical Pharmacology and Therapeutics
, vol.71
, Issue.4
, pp. 297-303
-
-
Nakamura, T.1
Sakaeda, T.2
Horinouchi, M.3
Tamura, T.4
Aoyama, N.5
Shirakawa, T.6
Matsuo, M.7
Kasuga, M.8
Okumura, K.9
-
75
-
-
9044254525
-
P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
-
DOI 10.1097/00008571-199602000-00002
-
D. R. Nelson L. Koymans T. Kamataki J. J. Stegeman R. Feyereisen D. J. Waxman M. R. Waterman O. Gotoh M. J. Coon R. W. Estabrook I. C. Gunsalus D. W. Nebert 1996 P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature Pharmacogenetics 6 1 42 8845856 1:CAS:528: DyaK28XisFyhsLg%3D (Pubitemid 26096749)
-
(1996)
Pharmacogenetics
, vol.6
, Issue.1
, pp. 1-42
-
-
Nelson, D.R.1
Koymans, L.2
Kamataki, T.3
Stegeman, J.J.4
Feyereisen, R.5
Waxman, D.J.6
Waterman, M.R.7
Gotoh, O.8
Coon, M.J.9
Estabrook, R.W.10
Gunsalus, I.C.11
Nebert, D.W.12
-
76
-
-
16544363963
-
Ethnic differences in genetic polymorphisms of CYP2D6, CYP2C19, CYP3As and MDR1/ABCB1
-
15499174 1:CAS:528:DC%2BD2cXlsFKjs7w%3D
-
S. Ozawa A. Soyama M. Saeki H. Fukushima-Uesaka M. Itoda S. Koyano K. Sai Y. Ohno Y. Saito J. Sawada 2004 Ethnic differences in genetic polymorphisms of CYP2D6, CYP2C19, CYP3As and MDR1/ABCB1 Drug Metab. Pharmacokinet. 19 83 95 15499174 1:CAS:528:DC%2BD2cXlsFKjs7w%3D
-
(2004)
Drug Metab. Pharmacokinet.
, vol.19
, pp. 83-95
-
-
Ozawa, S.1
Soyama, A.2
Saeki, M.3
Fukushima-Uesaka, H.4
Itoda, M.5
Koyano, S.6
Sai, K.7
Ohno, Y.8
Saito, Y.9
Sawada, J.10
-
77
-
-
71949127231
-
Interplay of transporters and enzymes in drug and metabolite processing
-
19891494 1:CAS:528:DC%2BD1MXhsFShsrzP
-
K. S. Pang H. J. Maeng J. Fan 2009 Interplay of transporters and enzymes in drug and metabolite processing Mol. Pharm. 6 1734 1755 19891494 1:CAS:528:DC%2BD1MXhsFShsrzP
-
(2009)
Mol. Pharm.
, vol.6
, pp. 1734-1755
-
-
Pang, K.S.1
Maeng, H.J.2
Fan, J.3
-
78
-
-
0034888241
-
Cytochrome P450 2D6.1 and cytochrome P450 2D6.10 differ in catalytic activity for multiple substrates
-
DOI 10.1097/00008571-200108000-00003
-
Y. Ramamoorthy R. F. Tyndale E. M. Sellers 2001 Cytochrome P450 2D6.1 and cytochrome P450 2D6.10 differ in catalytic activity for multiple substrates Pharmacogenetics 11 477 487 11505218 1:CAS:528:DC%2BD3MXmslynsLg%3D (Pubitemid 32778226)
-
(2001)
Pharmacogenetics
, vol.11
, Issue.6
, pp. 477-487
-
-
Ramamoorthy, Y.1
Tyndale, R.F.2
Sellers, E.M.3
-
80
-
-
0035464647
-
Plasma concentrations of haloperidol are related to CYP2D6 genotype at low, but not high doses of haloperidol in Korean schizophrenic patients
-
H. K. Roh J. Y. Chung D. Y. Oh C. S. Park J. O. Svensson M. L. Dahl L. Bertilsson 2001 Plasma concentrations of haloperidol are related to CYP2D6 genotype at low, but not high doses of haloperidol in Korean schizophrenic patients Br. J. Clin. Pharmacol. 52 265 271 11560558 1:CAS:528: DC%2BD3MXntFCnsLY%3D (Pubitemid 33796223)
-
(2001)
British Journal of Clinical Pharmacology, Supplement
, vol.52
, Issue.3
, pp. 265-271
-
-
Roh, H.-K.1
Chung, J.-Y.2
Oh, D.-Y.3
Park, C.-S.4
Svensson, J.-O.5
Dahl, M.-L.6
Bertilsson, L.7
-
81
-
-
0034771497
-
MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects
-
DOI 10.1023/A:1012244520615
-
T. Sakaeda T. Nakamura M. Horinouchi M. Kakumoto N. Ohmoto T. Sakai Y. Morita T. Tamura N. Aoyama M. Hirai M. Kasuga K. Okumura 2001 MDR1 genotyperelated pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects Pharm. Res. 18 1400 1404 11697464 1:CAS:528: DC%2BD3MXotVShsL0%3D (Pubitemid 32977244)
-
(2001)
Pharmaceutical Research
, vol.18
, Issue.10
, pp. 1400-1404
-
-
Sakaeda, T.1
Nakamura, T.2
Horinouchi, M.3
Kakumoto, M.4
Ohmoto, N.5
Sakai, T.6
Morita, Y.7
Tamura, T.8
Aoyama, N.9
Hirai, M.10
Kasuga, M.11
Okumura, K.12
-
82
-
-
4544373032
-
Pharmacogenetics of drug transporters and its impact on the pharmacotherapy
-
T. Sakaeda T. Nakamura K. Okumura 2004 Pharmacogenetics of drug transporters and its impact on the pharmacotherapy Curr. Top. Med. Chem. 4 1385 1398 15379652 1:CAS:528:DC%2BD2cXnslCms7o%3D (Pubitemid 39242880)
-
(2004)
Current Topics in Medicinal Chemistry
, vol.4
, Issue.13
, pp. 1385-1398
-
-
Sakaeda, T.1
Nakamura, T.2
Okumura, K.3
-
83
-
-
0029098340
-
Multidrug resistance and the role of P-glycoprotein knockout mice
-
7577039 1:CAS:528:DyaK2MXotVOmt7o%3D
-
A. H. Schinkel C. A. Mol E. Wagenaar L. Van Deemter J. J. Smit P. Borst 1995 Multidrug resistance and the role of P-glycoprotein knockout mice Eur. J. Cancer 31A 1295 1298 7577039 1:CAS:528:DyaK2MXotVOmt7o%3D
-
(1995)
Eur. J. Cancer
, vol.31
, pp. 1295-1298
-
-
Schinkel, A.H.1
Mol, C.A.2
Wagenaar, E.3
Van Deemter, L.4
Smit, J.J.5
Borst, P.6
-
84
-
-
0029892497
-
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
-
A. H. Schinkel E. Wagenaar C. A. Mol L. Van Deemter 1996 P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs J. Clin. Invest. 97 2517 2524 8647944 1:CAS:528:DyaK28XjsFKjs7Y%3D (Pubitemid 26187339)
-
(1996)
Journal of Clinical Investigation
, vol.97
, Issue.11
, pp. 2517-2524
-
-
Schinkel, A.H.1
Wagenaar, E.2
Mol, C.A.A.M.3
Van Deemter, L.4
-
85
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
T. Shimada H. Yamazaki M. Mimura Y. Inui F. P. Guengerich 1994 Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians J. Pharmacol. Exp. Ther. 270 414 423 8035341 1:CAS:528:DyaK2cXlt1OmtL4%3D (Pubitemid 24229655)
-
(1994)
Journal of Pharmacology and Experimental Therapeutics
, vol.270
, Issue.1
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
Inui, Y.4
Guengerich, F.P.5
-
86
-
-
65249165999
-
Functional polymorphism of the human multidrug resistance gene (MDR1) and polydipsia-hyponatremia in schizophrenia
-
18543120 1:CAS:528:DC%2BD1MXhtlKrsQ%3D%3D
-
T. Shinkai V. De Luca K. Utsunomiya S. Sakata Y. Inoue Y. Fukunaka R. Hwang O. Ohmori J. L. Kennedy J. Nakamura 2008 Functional polymorphism of the human multidrug resistance gene (MDR1) and polydipsia-hyponatremia in schizophrenia Neuromolecular Med. 10 362 367 18543120 1:CAS:528: DC%2BD1MXhtlKrsQ%3D%3D
-
(2008)
Neuromolecular Med.
, vol.10
, pp. 362-367
-
-
Shinkai, T.1
De Luca, V.2
Utsunomiya, K.3
Sakata, S.4
Inoue, Y.5
Fukunaka, Y.6
Hwang, R.7
Ohmori, O.8
Kennedy, J.L.9
Nakamura, J.10
-
87
-
-
0036217595
-
Effects of CYP2C19 and CYP2C9 genetic polymorphisms on the disposition of and blood glucose lowering response to tolbutamide in humans
-
DOI 10.1097/00008571-200203000-00005
-
J. H. Shon Y. R. Yoon K. A. Kim Y. C. Lim K. J. Lee J. Y. Park I. J. Cha D. A. Flockhart J. G. Shin 2002 Effects of CYP2C19 and CYP2C9 genetic polymorphisms on the disposition of and blood glucose lowering response to tolbutamide in humans Pharmacogenetics 12 111 119 11875365 1:CAS:528: DC%2BD38XnsFKqsbo%3D (Pubitemid 34298915)
-
(2002)
Pharmacogenetics
, vol.12
, Issue.2
, pp. 111-119
-
-
Shon, J.-H.1
Yoon, Y.-R.2
Kim, K.-A.3
Lim, Y.-C.4
Lee, K.-J.5
Park, J.-Y.6
Cha, I.-J.7
Flockhart, D.A.8
Shin, J.-G.9
-
88
-
-
0036881077
-
The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol
-
DOI 10.1067/mcp.2002.127739
-
W. Siegmund K. Ludwig T. Giessmann P. Dazert E. Schroeder B. Sperker R. Warzok H. K. Kroemer I. Cascorbi 2002 The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol Clin. Pharmacol. Ther. 72 572 583 12426521 1:CAS:528: DC%2BD38XpsFSisbo%3D (Pubitemid 36237729)
-
(2002)
Clinical Pharmacology and Therapeutics
, vol.72
, Issue.5
, pp. 572-583
-
-
Siegmund, W.1
Ludwig, K.2
Giessmann, T.3
Dazert, P.4
Schroeder, E.5
Sperker, B.6
Warzok, R.7
Kroemer, H.K.8
Cascorbi, I.9
-
89
-
-
55349099134
-
Dual drug interactions via P-glycoprotein (Pgp)/cytochrome P450 (CYP3A4) interplay: Recent case study of oral atorvastatin and verapamil
-
18661126
-
N. R. Srinivas 2008 Dual drug interactions via P-glycoprotein (Pgp)/cytochrome P450 (CYP3A4) interplay: recent case study of oral atorvastatin and verapamil Eur. J. Clin. Pharmacol. 64 1135 1136 18661126
-
(2008)
Eur. J. Clin. Pharmacol.
, vol.64
, pp. 1135-1136
-
-
Srinivas, N.R.1
-
90
-
-
20344375240
-
Impact of CYP3A5 and MDR1(ABCB1) C3435T polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients
-
DOI 10.1016/j.transproceed.2005.02.073, PII S0041134505001909
-
H. Tada N. Tsuchiya S. Satoh H. Kagaya Z. Li K. Sato M. Miura T. Suzuki T. Kato T. Habuchi 2005 Impact of CYP3A5 and MDR1(ABCB1) C3435T polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients Transplant. Proc. 37 1730 1732 15919447 1:CAS:528:DC%2BD2MXks1Crs78%3D (Pubitemid 40790812)
-
(2005)
Transplantation Proceedings
, vol.37
, Issue.4
, pp. 1730-1732
-
-
Tada, H.1
Tsuchiya, N.2
Satoh, S.3
Kagaya, H.4
Li, Z.5
Sato, K.6
Miura, M.7
Suzuki, T.8
Kato, T.9
Habuchi, T.10
-
91
-
-
0034997034
-
Expression of P-glycoprotein in human placenta: Relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene
-
M. Tanabe I. Ieiri N. Nagata K. Inoue S. Ito Y. Kanamori M. Takahashi Y. Kurata J. Kigawa S. Higuchi N. Terakawa K. Otsubo 2001 Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene J. Pharmacol. Exp. Ther. 297 1137 1143 11356939 1:CAS:528:DC%2BD3MXjvVShs7k%3D (Pubitemid 32472514)
-
(2001)
Journal of Pharmacology and Experimental Therapeutics
, vol.297
, Issue.3
, pp. 1137-1143
-
-
Tanabe, M.1
Ieiri, I.2
Nagata, N.3
Inoue, K.4
Ito, S.5
Kanamori, Y.6
Takahashi, M.7
Kurata, Y.8
Kigawa, J.9
Higuchi, S.10
Terakawa, N.11
Otsubo, K.12
-
92
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
2444983 1:CAS:528:DyaL2sXmtlels7k%3D
-
F. Thiebaut T. Tsuruo H. Hamada M. M. Gottesman I. Pastan M. C. Willingham 1987 Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues Proc. Natl. Acad. Sci. U. S. A. 84 7735 7738 2444983 1:CAS:528:DyaL2sXmtlels7k%3D
-
(1987)
Proc. Natl. Acad. Sci. U. S. A.
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
93
-
-
38149003759
-
Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression
-
18215618 1:CAS:528:DC%2BD1cXhvVSrt74%3D
-
M. Uhr A. Tontsch C. Namendorf S. Ripke S. Lucae M. Ising T. Dose M. Ebinger M. Rosenhagen M. Kohli S. Kloiber D. Salyakina T. Bettecken M. Specht B. Putz E. B. Binder B. Muller-Myhsok F. Holsboer 2008 Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression Neuron 57 203 209 18215618 1:CAS:528:DC%2BD1cXhvVSrt74%3D
-
(2008)
Neuron
, vol.57
, pp. 203-209
-
-
Uhr, M.1
Tontsch, A.2
Namendorf, C.3
Ripke, S.4
Lucae, S.5
Ising, M.6
Dose, T.7
Ebinger, M.8
Rosenhagen, M.9
Kohli, M.10
Kloiber, S.11
Salyakina, D.12
Bettecken, T.13
Specht, M.14
Putz, B.15
Binder, E.B.16
Muller-Myhsok, B.17
Holsboer, F.18
-
94
-
-
0034744113
-
No influence of the MDR-I C3435T polymorphism or a CYP3A4 promoter polymorphism (CYP3A4-V allele) on dose-adjusted cyclosporin a trough concentrations or rejection incidence in stable renal transplant recipients
-
N. Von Ahsen M. Richter C. Grupp B. Ringe M. Oellerich V. W. Armstrong 2001 No influence of the MDR-1 C3435T polymorphism or a CYP3A4 promoter polymorphism (CYP3A4-V allele) on dose-adjusted cyclosporin A trough concentrations or rejection incidence in stable renal transplant recipients Clin. Chem. 47 1048 1052 (Pubitemid 32493590)
-
(2001)
Clinical Chemistry
, vol.47
, Issue.6
, pp. 1048-1052
-
-
Von Ahsen, N.1
Richter, M.2
Grupp, C.3
Ringe, B.4
Oellerich, M.5
Armstrong, V.W.6
-
95
-
-
0033861614
-
CYP3A activity in African American and European American men: Population differences and functional effect of the CΥP3A41B 5'-promoter region polymorphism
-
DOI 10.1067/mcp.2000.108506
-
C. Wandel J. S. Witte J. M. Hall C. M. Stein A. J. Wood G. R. Wilkinson 2000 CYP3A activity in African American and European American men: population differences and functional effect of the CYP3A41B5'-promoter region polymorphism Clin. Pharmacol. Ther. 68 82 91 10945319 1:CAS:528:DC%2BD3cXlvVOrsL0%3D (Pubitemid 30609830)
-
(2000)
Clinical Pharmacology and Therapeutics
, vol.68
, Issue.1
, pp. 82-91
-
-
Wandel, C.1
Witte, J.S.2
Hall, J.M.3
Stein, C.M.4
Wood, A.J.J.5
Wilkinson, G.R.6
-
97
-
-
0025735576
-
The activation of the biguanide antimalarial proguanil co-segregates with the mephenytoin oxidation polymorphism-A panel study
-
1867963 1:CAS:528:DyaK3MXks1equr4%3D
-
S. A. Ward N. A. Helsby E. Skjelbo K. Brosen L. F. Gram A. M. Breckenridge 1991 The activation of the biguanide antimalarial proguanil co-segregates with the mephenytoin oxidation polymorphism-a panel study Br. J. Clin. Pharmacol. 31 689 692 1867963 1:CAS:528:DyaK3MXks1equr4%3D
-
(1991)
Br. J. Clin. Pharmacol.
, vol.31
, pp. 689-692
-
-
Ward, S.A.1
Helsby, N.A.2
Skjelbo, E.3
Brosen, K.4
Gram, L.F.5
Breckenridge, A.M.6
-
98
-
-
0037421584
-
Inheritance and drug response
-
DOI 10.1056/NEJMra020021
-
R. Weinshilboum 2003 Inheritance and drug response N. Engl. J. Med. 348 529 537 12571261 (Pubitemid 36159889)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.6
, pp. 529-537
-
-
Weinshilboum, R.1
-
99
-
-
58849130987
-
CYP2C19 genotype is a major factor contributing to the highly variable pharmacokinetics of voriconazole
-
19033450 1:CAS:528:DC%2BD1MXisFCisrc%3D
-
J. Weiss M. M. Ten Hoevel J. Burhenne I. Walter-Sack M. M. Hoffmann J. Rengelshausen W. E. Haefeli G. Mikus 2009 CYP2C19 genotype is a major factor contributing to the highly variable pharmacokinetics of voriconazole J. Clin. Pharmacol. 49 196 204 19033450 1:CAS:528:DC%2BD1MXisFCisrc%3D
-
(2009)
J. Clin. Pharmacol.
, vol.49
, pp. 196-204
-
-
Weiss, J.1
Ten Hoevel, M.M.2
Burhenne, J.3
Walter-Sack, I.4
Hoffmann, M.M.5
Rengelshausen, J.6
Haefeli, W.E.7
Mikus, G.8
-
100
-
-
0345643389
-
Interindividual differences in hepatic expression of CYP3A4: Relationship to genetic polymorphism in the 5'-upstream regulatory region
-
DOI 10.1006/bbrc.1999.0752
-
A. Westlind L. Lofberg N. Tindberg T. B. Andersson M. Ingelman-Sundberg 1999 Interindividual differences in hepatic expression of CYP3A4: relationship to genetic polymorphism in the 5'-upstream regulatory region Biochem. Biophys. Res. Commun. 259 201 205 10334940 1:CAS:528:DyaK1MXjtFKgsr4%3D (Pubitemid 29264018)
-
(1999)
Biochemical and Biophysical Research Communications
, vol.259
, Issue.1
, pp. 201-205
-
-
Westlind, A.1
Lofberg, L.2
Tindberg, N.3
Andersson, T.B.4
Ingelman-Sundberg, M.5
-
101
-
-
17644380257
-
Predicting drug disposition via application of BCS: Transport/absorption/ elimination interplay and development of a biopharmaceutics drug disposition classification system
-
DOI 10.1007/s11095-004-9004-4
-
C. Y. Wu L. Z. Benet 2005 Predicting drug disposition via application of BCS: transport/absorption/ elimination interplay and development of a biopharmaceutics drug disposition classification system Pharm. Res. 22 11 23 15771225 1:CAS:528:DC%2BD2MXhtlCks70%3D (Pubitemid 40558141)
-
(2005)
Pharmaceutical Research
, vol.22
, Issue.1
, pp. 11-23
-
-
Wu, C.-Y.1
Benet, L.Z.2
-
102
-
-
0037131892
-
CYP2C9 allelic variants: Ethnic distribution and functional significance
-
DOI 10.1016/S0169-409X(02)00076-5, PII S0169409X02000765
-
H. G. Xie H. C. Prasad R. B. Kim C. M. Stein 2002 CYP2C9 allelic variants: ethnic distribution and functional significance Adv. Drug Deliv. Rev. 54 1257 1270 12406644 1:CAS:528:DC%2BD38XotF2jurk%3D (Pubitemid 35284252)
-
(2002)
Advanced Drug Delivery Reviews
, vol.54
, Issue.10
, pp. 1257-1270
-
-
Xie, H.-G.1
Prasad, H.C.2
Kim, R.B.3
Stein, C.M.4
-
103
-
-
0037906108
-
The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients
-
C. R. Yates W. Zhang P. Song S. Li A. O. Gaber M. Kotb M. R. Honaker R. R. Alloway B. Meibohm 2003 The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients J. Clin. Pharmacol. 43 555 564 12817518 1:CAS:528:DC%2BD3sXkslGhsLg%3D (Pubitemid 36613114)
-
(2003)
Journal of Clinical Pharmacology
, vol.43
, Issue.6
, pp. 555-564
-
-
Yates, C.R.1
Zhang, W.2
Song, P.3
Li, S.4
Gaber, A.O.5
Kotb, M.6
Honaker, M.R.7
Alloway, R.R.8
Meibohm, B.9
-
104
-
-
69449091820
-
Influence of CYP3A and CYP2C19 genetic polymorphisms on the pharmacokinetics of cilostazol in healthy subjects
-
19516253 1:CAS:528:DC%2BD1MXhtVGqu7nE
-
H. D. Yoo S. A. Park H. Y. Cho Y. B. Lee 2009 Influence of CYP3A and CYP2C19 genetic polymorphisms on the pharmacokinetics of cilostazol in healthy subjects Clin. Pharmacol. Ther. 86 281 284 19516253 1:CAS:528:DC%2BD1MXhtVGqu7nE
-
(2009)
Clin. Pharmacol. Ther.
, vol.86
, pp. 281-284
-
-
Yoo, H.D.1
Park, S.A.2
Cho, H.Y.3
Lee, Y.B.4
-
105
-
-
72949113621
-
Population pharmacokinetic analysis of cilostazol in healthy subjects with genetic polymorphisms of CYP3A5, CYP2C19 and ABCB1
-
20078610 1:CAS:528:DC%2BC3cXhvFSltb4%3D
-
H. D. Yoo H. Y. Cho Y. B. Lee 2010 Population pharmacokinetic analysis of cilostazol in healthy subjects with genetic polymorphisms of CYP3A5, CYP2C19 and ABCB1 Br. J. Clin. Pharmacol. 69 27 37 20078610 1:CAS:528: DC%2BC3cXhvFSltb4%3D
-
(2010)
Br. J. Clin. Pharmacol.
, vol.69
, pp. 27-37
-
-
Yoo, H.D.1
Cho, H.Y.2
Lee, Y.B.3
-
106
-
-
80054784499
-
Population pharmacokinetic analysis of glimepiride with CYP2C9 genetic polymorphism in healthy Korean subjects
-
21476064 1:CAS:528:DC%2BC3MXhtVWqtbnL
-
H. D. Yoo M. S. Kim H. Y. Cho Y. B. Lee 2011 Population pharmacokinetic analysis of glimepiride with CYP2C9 genetic polymorphism in healthy Korean subjects Eur. J. Clin. Pharmacol. 67 889 898 21476064 1:CAS:528: DC%2BC3MXhtVWqtbnL
-
(2011)
Eur. J. Clin. Pharmacol.
, vol.67
, pp. 889-898
-
-
Yoo, H.D.1
Kim, M.S.2
Cho, H.Y.3
Lee, Y.B.4
-
107
-
-
80051777982
-
Influence of ABCB1 genetic polymorphisms on the pharmacokinetics of risperidone in healthy subjects with CYP2D610/10
-
21449914 1:CAS:528:DC%2BC3MXhtFWqsLfJ
-
H. D. Yoo S. N. Lee H. A. Kang H. Y. Cho I. K. Lee Y. B. Lee 2011 Influence of ABCB1 genetic polymorphisms on the pharmacokinetics of risperidone in healthy subjects with CYP2D610/10 Br. J. Pharmacol. 164 433 443 21449914 1:CAS:528:DC%2BC3MXhtFWqsLfJ
-
(2011)
Br. J. Pharmacol.
, vol.164
, pp. 433-443
-
-
Yoo, H.D.1
Lee, S.N.2
Kang, H.A.3
Cho, H.Y.4
Lee, I.K.5
Lee, Y.B.6
-
108
-
-
0142185029
-
A simple method for the detection of CYP2C9 polymorphisms: Nested allele-specific multiplex polymerase chain reaction
-
DOI 10.1016/S0009-8981(03)00319-X
-
Z. Zainuddin L. K. Teh A. W. Suhaimi M. Z. Salleh R. Ismail 2003 A simple method for the detection of CYP2C9 polymorphisms: nested allele-specific multiplex polymerase chain reaction Clin. Chim. Acta 336 97 102 14500040 1:CAS:528:DC%2BD3sXnt1Gnurk%3D (Pubitemid 37324759)
-
(2003)
Clinica Chimica Acta
, vol.336
, Issue.1-2
, pp. 97-102
-
-
Zainuddin, Z.1
Teh, L.K.2
Suhaimi, A.W.M.3
Salleh, M.Z.4
Ismail, R.5
-
109
-
-
47349110179
-
Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition
-
18668431 1:CAS:528:DC%2BD1cXpt1SnurY%3D
-
S. F. Zhou 2008 Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition Xenobiotica 38 802 832 18668431 1:CAS:528:DC%2BD1cXpt1SnurY%3D
-
(2008)
Xenobiotica
, vol.38
, pp. 802-832
-
-
Zhou, S.F.1
|