-
1
-
-
15444342300
-
Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2
-
Abe T., Kakyo M., Sakagami H., Tokui T., Nishio T., Tanemoto M., Nomura H., Hebert S.C., Matsuno S., Kondo T., Yawo H. Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2. J. Biol. Chem. 173:1998;22395-22401.
-
(1998)
J. Biol. Chem.
, vol.173
, pp. 22395-22401
-
-
Abe, T.1
Kakyo, M.2
Sakagami, H.3
Tokui, T.4
Nishio, T.5
Tanemoto, M.6
Nomura, H.7
Hebert, S.C.8
Matsuno, S.9
Kondo, T.10
Yawo, H.11
-
2
-
-
0040368659
-
Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1
-
Abe T., Kakyo M., Tokui T., Nakagomi R., Nishio T., Nakai D., Nomura H., Unno M., Suzuki M., Naitoh T., Matsuno S., Yawo H. Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1. J. Biol. Chem. 274:1999;17159-17163.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17159-17163
-
-
Abe, T.1
Kakyo, M.2
Tokui, T.3
Nakagomi, R.4
Nishio, T.5
Nakai, D.6
Nomura, H.7
Unno, M.8
Suzuki, M.9
Naitoh, T.10
Matsuno, S.11
Yawo, H.12
-
3
-
-
0030098277
-
Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver
-
Bossuyt X., Müller M., Hagenbuch B., Meier P.J. Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver. J. Pharmacol. Exp. Ther. 276:1996;891-896.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.276
, pp. 891-896
-
-
Bossuyt, X.1
Müller, M.2
Hagenbuch, B.3
Meier, P.J.4
-
4
-
-
0000712439
-
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
-
Cordon-Cardo C., O'Brien J.P., Casals D., Rittman-Grauer L., Biedler J.L., Melamed M.R., Bertino J.R. Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. Proc. Natl. Acad. Sci. 86:1989;695-698.
-
(1989)
Proc. Natl. Acad. Sci.
, vol.86
, pp. 695-698
-
-
Cordon-Cardo, C.1
O'Brien, J.P.2
Casals, D.3
Rittman-Grauer, L.4
Biedler, J.L.5
Melamed, M.R.6
Bertino, J.R.7
-
5
-
-
0032793959
-
OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine
-
Cvetkovic M., Leake B., Fromm M.F., Wilkinson G.R., Kim R.B. OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine. Drug Metab. Dispos. 27:1999;866-871.
-
(1999)
Drug Metab. Dispos.
, vol.27
, pp. 866-871
-
-
Cvetkovic, M.1
Leake, B.2
Fromm, M.F.3
Wilkinson, G.R.4
Kim, R.B.5
-
6
-
-
15844387507
-
The peptide-based thrombin inhibitor CRC 220 is a new substrate of the basolateral rat liver organic anion-transporting polypeptide
-
Eckhardt U., Horz J.A., Petzinger E., Stuber W., Reers M., Dickneite G., Daniel H., Wagener M., Hagenbuch B., Stieger B., Meier P.J. The peptide-based thrombin inhibitor CRC 220 is a new substrate of the basolateral rat liver organic anion-transporting polypeptide. Hepatology. 24:1996;380-384.
-
(1996)
Hepatology
, vol.24
, pp. 380-384
-
-
Eckhardt, U.1
Horz, J.A.2
Petzinger, E.3
Stuber, W.4
Reers, M.5
Dickneite, G.6
Daniel, H.7
Wagener, M.8
Hagenbuch, B.9
Stieger, B.10
Meier, P.J.11
-
7
-
-
0028333611
-
Expression cloning of a mammalian proton-coupled oligopeptide transporter
-
Fei Y.-J., Kanai Y., Nussberger S., Ganapathy V., Leibach F.H., Romero M.F., Singh S.K., Boron W.F., Hediger M.A. Expression cloning of a mammalian proton-coupled oligopeptide transporter. Nature. 368:1994;563-566.
-
(1994)
Nature
, vol.368
, pp. 563-566
-
-
Fei, Y.-J.1
Kanai, Y.2
Nussberger, S.3
Ganapathy, V.4
Leibach, F.H.5
Romero, M.F.6
Singh, S.K.7
Boron, W.F.8
Hediger, M.A.9
-
8
-
-
0033514320
-
Inhibition of P-Glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine
-
Fromm M.F., Kim R.B., Stein C.M., Wilkinson G.R., Roden D.M. Inhibition of P-Glycoprotein-mediated drug transport: a unifying mechanism to explain the interaction between digoxin and quinidine. Circulation. 99:1999a;552-557.
-
(1999)
Circulation
, vol.99
, pp. 552-557
-
-
Fromm, M.F.1
Kim, R.B.2
Stein, C.M.3
Wilkinson, G.R.4
Roden, D.M.5
-
9
-
-
0032922395
-
Human MRP3 transporter: Identification of the 5′-flanking region, genomic organization and alternative splice variants
-
Fromm M.F., Leake B., Roden D.M., Wilkinson G.R., Kim R.B. Human MRP3 transporter: identification of the 5′-flanking region, genomic organization and alternative splice variants. Biochim. Biophys. Acta. 1415:1999b;369-374.
-
(1999)
Biochim. Biophys. Acta
, vol.1415
, pp. 369-374
-
-
Fromm, M.F.1
Leake, B.2
Roden, D.M.3
Wilkinson, G.R.4
Kim, R.B.5
-
10
-
-
0032859340
-
Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain
-
Gao B., Stieger B., Noe B., Fritschy J.M., Meier P.J. Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain. J. Histochem. Cytochem. 47:1999;1255-1264.
-
(1999)
J. Histochem. Cytochem.
, vol.47
, pp. 1255-1264
-
-
Gao, B.1
Stieger, B.2
Noe, B.3
Fritschy, J.M.4
Meier, P.J.5
-
11
-
-
0032540277
-
The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver
-
Gerloff T., Stieger B., Hagenbuch B., Madon J., Landmann L., Roth J., Hofmann A.F., Meier P.J. The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver. J. Biol. Chem. 273:1998;10046-10050.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10046-10050
-
-
Gerloff, T.1
Stieger, B.2
Hagenbuch, B.3
Madon, J.4
Landmann, L.5
Roth, J.6
Hofmann, A.F.7
Meier, P.J.8
-
12
-
-
0027954308
-
Catalytic selectivity of human cytochrome P450 enzymes: Relevance to drug metabolism and toxicity
-
Guengerich F.P. Catalytic selectivity of human cytochrome P450 enzymes: relevance to drug metabolism and toxicity. Toxicol. Let. 70:1994;133-138.
-
(1994)
Toxicol. Let.
, vol.70
, pp. 133-138
-
-
Guengerich, F.P.1
-
15
-
-
0029822980
-
Effect of antisense oligonucleotides on the expression of hepatocellular bile acid and organic anion uptake systems in Xenopus laevis oocytes
-
Hagenbuch B., Scharschmidt B.F., Meier P.J. Effect of antisense oligonucleotides on the expression of hepatocellular bile acid and organic anion uptake systems in Xenopus laevis oocytes. Biochem. J. 316:1996;901-904.
-
(1996)
Biochem. J.
, vol.316
, pp. 901-904
-
-
Hagenbuch, B.1
Scharschmidt, B.F.2
Meier, P.J.3
-
17
-
-
0031866357
-
Hepatic expression of multidrug resistance-associated protein-like proteins maintained in eisai hyperbilirubinemic rats
-
Hirohashi T., Suzuki H., Ito K., Ogawa K., Kume K., Shimizu T., Sugiyama Y. Hepatic expression of multidrug resistance-associated protein-like proteins maintained in eisai hyperbilirubinemic rats. Mol. Pharmacol. 53:1998;1068-1075.
-
(1998)
Mol. Pharmacol.
, vol.53
, pp. 1068-1075
-
-
Hirohashi, T.1
Suzuki, H.2
Ito, K.3
Ogawa, K.4
Kume, K.5
Shimizu, T.6
Sugiyama, Y.7
-
18
-
-
0027950807
-
Inhibition of rat hepatocyte organic anion transport by bile acids
-
Ishi K., Wolkoff A.W. Inhibition of rat hepatocyte organic anion transport by bile acids. Am. J. Physiol. 267:1994;g-458-g-464.
-
(1994)
Am. J. Physiol.
, vol.267
-
-
Ishi, K.1
Wolkoff, A.W.2
-
20
-
-
0032869932
-
Molecular characterization and functional regulation of a novel rat liver-specific organic anion transporter rlst-1
-
Kakyo M., Unno M., Tokui T., Nakagomi R., Nishio T., Iwasashi H., Nakai D., Seki M., Suzuki M., Naitoh T., Matsuno S., Yawo H., Abe T. Molecular characterization and functional regulation of a novel rat liver-specific organic anion transporter rlst-1. Gastroenterology. 117:1999;770-775.
-
(1999)
Gastroenterology
, vol.117
, pp. 770-775
-
-
Kakyo, M.1
Unno, M.2
Tokui, T.3
Nakagomi, R.4
Nishio, T.5
Iwasashi, H.6
Nakai, D.7
Seki, M.8
Suzuki, M.9
Naitoh, T.10
Matsuno, S.11
Yawo, H.12
Abe, T.13
-
21
-
-
0029876335
-
Estradiol 17b-D-glucuronide is a high-affinity substrate for oatp organic anion transporter
-
Kanai N., Lu R., Bao Y., Wolkoff A.W., Vore M., Schuster V.L. Estradiol 17b-D-glucuronide is a high-affinity substrate for oatp organic anion transporter. Am. J. Physiol. 270:1996;F326-F331.
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Kanai, N.1
Lu, R.2
Bao, Y.3
Wolkoff, A.W.4
Vore, M.5
Schuster, V.L.6
-
22
-
-
0029078231
-
Identification and characterization of a prostaglandin transporter
-
Kanai N., Lu R., Satriano J.A., Bao Y., Wolkoff A.W., Schuster V.L. Identification and characterization of a prostaglandin transporter. Science. 268:1995;866-869.
-
(1995)
Science
, vol.268
, pp. 866-869
-
-
Kanai, N.1
Lu, R.2
Satriano, J.A.3
Bao, Y.4
Wolkoff, A.W.5
Schuster, V.L.6
-
23
-
-
0032518290
-
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors
-
Kim R.B., Fromm M.F., Wandel C., Leake B., Wood A.J.J., Roden D.M., Wilkinson G.R. The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. J. Clin. Invest. 101:1998;289-294.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 289-294
-
-
Kim, R.B.1
Fromm, M.F.2
Wandel, C.3
Leake, B.4
Wood, A.J.J.5
Roden, D.M.6
Wilkinson, G.R.7
-
24
-
-
0032907322
-
Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein
-
Kim R.B., Wandel C., Leake B., Cvetkovic M., Fromm M.F., Dempsey P.J., Roden M.M., Belas F., Chaudhary A.K., Roden D.M., Wood A.J., Wilkinson G.R. Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein. Pharm. Res. 16:1999;408-414.
-
(1999)
Pharm. Res.
, vol.16
, pp. 408-414
-
-
Kim, R.B.1
Wandel, C.2
Leake, B.3
Cvetkovic, M.4
Fromm, M.F.5
Dempsey, P.J.6
Roden, M.M.7
Belas, F.8
Chaudhary, A.K.9
Roden, D.M.10
Wood, A.J.11
Wilkinson, G.R.12
-
25
-
-
0034725617
-
Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide
-
Konig J., Cui Y., Nies A.T., Keppler D. Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide. J. Biol. Chem. 275:2000;23161-23168.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23161-23168
-
-
Konig, J.1
Cui, Y.2
Nies, A.T.3
Keppler, D.4
-
26
-
-
0032926354
-
Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane
-
Konig J., Rost D., Cui Y., Keppler D. Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane. Hepatology. 29:1999;1156-1163.
-
(1999)
Hepatology
, vol.29
, pp. 1156-1163
-
-
Konig, J.1
Rost, D.2
Cui, Y.3
Keppler, D.4
-
27
-
-
0035125407
-
Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver
-
Kullak-Ublick G.A., Ismair M.G., Stieger B., Landmann L., Huber R., Pizzagalli F., Fattinger K., Meier P.J., Hagenbuch B. Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology. 120:2001;525-533.
-
(2001)
Gastroenterology
, vol.120
, pp. 525-533
-
-
Kullak-Ublick, G.A.1
Ismair, M.G.2
Stieger, B.3
Landmann, L.4
Huber, R.5
Pizzagalli, F.6
Fattinger, K.7
Meier, P.J.8
Hagenbuch, B.9
-
28
-
-
0029013159
-
P-glycoprotein and pharmacokinetics
-
Levêque D., Jehl F. P-glycoprotein and pharmacokinetics. Anticancer Res. 15:1995;331-336.
-
(1995)
Anticancer Res.
, vol.15
, pp. 331-336
-
-
Levêque, D.1
Jehl, F.2
-
29
-
-
0028920129
-
+ /peptide cotransport:cloing, functional expression, and chromosomal localization
-
+ /peptide cotransport:cloing, functional expression, and chromosomal localization. J. Biol. Chem. 270:1995;6456-6463.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 6456-6463
-
-
Liang, R.1
Fei, Y.-J.2
Prasad, P.D.3
Ramamoorthy, S.4
Han, H.5
Yang-Feng, T.L.6
Hediger, M.A.7
Ganapathy, V.8
Leibach, F.H.9
-
30
-
-
0030738677
-
Multidrug resistance: Molecular mechanisms and clinical relevance
-
Ling V. Multidrug resistance: molecular mechanisms and clinical relevance. Cancer Chemother. Pharmacol. 40:1997;S3-S8.
-
(1997)
Cancer Chemother. Pharmacol.
, vol.40
-
-
Ling, V.1
-
31
-
-
0029739973
-
Cloning, in vitro expression, and tissue distribution of a human prostaglandin transporter cDNA (hPGT)
-
Lu R., Kanai N., Schuster V.L. Cloning, in vitro expression, and tissue distribution of a human prostaglandin transporter cDNA (hPGT). J. Clin. Invest. 98:1996;1142-1149.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1142-1149
-
-
Lu, R.1
Kanai, N.2
Schuster, V.L.3
-
32
-
-
0030886124
-
Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain
-
Noe B., Hagenbuch B., Stieger B., Meier P.J. Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain. Proc. Natl. Acad. Sci. 94:1997;10346-10350.
-
(1997)
Proc. Natl. Acad. Sci.
, vol.94
, pp. 10346-10350
-
-
Noe, B.1
Hagenbuch, B.2
Stieger, B.3
Meier, P.J.4
-
33
-
-
0027944609
-
The role of the canalicular multispecific organic transporter in the disposal of endo- and xenobiotics
-
Oude Elferink R.P.J., Jansen P.L.M. The role of the canalicular multispecific organic transporter in the disposal of endo- and xenobiotics. Pharmacol. Ther. 64:1994;77-97.
-
(1994)
Pharmacol. Ther.
, vol.64
, pp. 77-97
-
-
Oude Elferink, R.P.J.1
Jansen, P.L.M.2
-
35
-
-
0029981430
-
Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene
-
Paulusma C.C., Bosma P.J., Zaman G.J.R., Bakker C.T.M., Otter M., Scheffer G.L., Scheper R.J., Borst P., Elferink R.P.J.O. Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. Science. 271:1996;1126-1128.
-
(1996)
Science
, vol.271
, pp. 1126-1128
-
-
Paulusma, C.C.1
Bosma, P.J.2
Zaman, G.J.R.3
Bakker, C.T.M.4
Otter, M.5
Scheffer, G.L.6
Scheper, R.J.7
Borst, P.8
Elferink, R.P.J.O.9
-
36
-
-
0030994468
-
A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome
-
Paulusma C.C., Kool M., Bosma P.J., Scheffer G.L., ter Borg F., Scheper R.J., Tytgat G.N., Borst P., Baas F., Oude E.R. A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome. Hepatology. 25:1997;1539-1542.
-
(1997)
Hepatology
, vol.25
, pp. 1539-1542
-
-
Paulusma, C.C.1
Kool, M.2
Bosma, P.J.3
Scheffer, G.L.4
Ter Borg, F.5
Scheper, R.J.6
Tytgat, G.N.7
Borst, P.8
Baas, F.9
Oude, E.R.10
-
37
-
-
0029786681
-
Cloning and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate in the kidney
-
Saito H., Masuda S., Inui K. Cloning and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate in the kidney. J. Biol. Chem. 271:1996;20719-20725.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20719-20725
-
-
Saito, H.1
Masuda, S.2
Inui, K.3
-
38
-
-
0028229150
-
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
Schinkel A.H., Smit J.J.M., van Tellingen O., Beijnen J.H., Wagenaar E., van Deemter L., Mol C.A.A.M., van der Valk M.A., Robanus-Maandag E.C., Riele H.P.J., Berns A.J.M., Borst P. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell. 77:1994;491-502.
-
(1994)
Cell
, vol.77
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.M.2
Van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.A.M.7
Van der Valk, M.A.8
Robanus-Maandag, E.C.9
Riele, H.P.J.10
Berns, A.J.M.11
Borst, P.12
-
39
-
-
0029892497
-
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
-
Schinkel A.H., Wagenaar E., Mol C.A., van Deemter L. P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J. Clin. Invest. 97:1996;2517-2524.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2517-2524
-
-
Schinkel, A.H.1
Wagenaar, E.2
Mol, C.A.3
Van Deemter, L.4
-
40
-
-
0028825399
-
Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A
-
Schinkel A.H., Wagenaar E., van Deemter L., Mol C.A.A.M., Borst P. Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. J. Clin. Invest. 96:1995;1698-1705.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 1698-1705
-
-
Schinkel, A.H.1
Wagenaar, E.2
Van Deemter, L.3
Mol, C.A.A.M.4
Borst, P.5
-
41
-
-
0030059953
-
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells
-
Schuetz E.G., Beck W.T., Schuetz J.D. Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. Mol. Pharmacol. 49:1996;311-318.
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 311-318
-
-
Schuetz, E.G.1
Beck, W.T.2
Schuetz, J.D.3
-
42
-
-
0034664729
-
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
-
Sinal C.J., Tohkin M., Miyata M., Ward J.M., Lambert G., Gonzalez F.J. Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell. 102:2000;731-744.
-
(2000)
Cell
, vol.102
, pp. 731-744
-
-
Sinal, C.J.1
Tohkin, M.2
Miyata, M.3
Ward, J.M.4
Lambert, G.5
Gonzalez, F.J.6
-
43
-
-
0027363563
-
Homozygous dusrupting of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
-
Smit J.J., Schinkel A.H., Oude Elferink R.P.J., Groen A.K., Wagenaar E., van Deemter L., Mol C.A.A.M., Ottenhoff R., van der Lugt N.M.T., van Roon M.A., van der Valk M.A., Offerhaus G.J.A., Berns A.J.M., Borst P. Homozygous dusrupting of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease. Cell. 75:1993;451-462.
-
(1993)
Cell
, vol.75
, pp. 451-462
-
-
Smit, J.J.1
Schinkel, A.H.2
Oude Elferink, R.P.J.3
Groen, A.K.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.A.M.7
Ottenhoff, R.8
Van der Lugt, N.M.T.9
Van Roon, M.A.10
Van der Valk, M.A.11
Offerhaus, G.J.A.12
Berns, A.J.M.13
Borst, P.14
-
44
-
-
0035853165
-
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity
-
Staudinger J.L., Goodwin B., Jones S.A., Hawkins-Brown D., MacKenzie K.I., LaTour A., Liu Y., Klaassen C.D., Brown K.K., Reinhard J., Willson T.M., Koller B.H., Kliewer S.A. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Proc. Natl. Acad. Sci. 98:2001;3369-3374.
-
(2001)
Proc. Natl. Acad. Sci.
, vol.98
, pp. 3369-3374
-
-
Staudinger, J.L.1
Goodwin, B.2
Jones, S.A.3
Hawkins-Brown, D.4
MacKenzie, K.I.5
LaTour, A.6
Liu, Y.7
Klaassen, C.D.8
Brown, K.K.9
Reinhard, J.10
Willson, T.M.11
Koller, B.H.12
Kliewer, S.A.13
-
45
-
-
17344366172
-
A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis
-
Strautnieks S.S., Bull L.N., Knisely A.S., Kocoshis S.A., Dahl N., Arnell H., Sokal E., Dahan K., Childs S., Ling V., Tanner M.S., Kagalwalla A.F., Nemeth A., Pawlowska J., Baker A., Mieli-Vergani G., Freimer N.B., Gardiner R.M., Thompson R.J. A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis. Nat. Genet. 20:1998;233-238.
-
(1998)
Nat. Genet.
, vol.20
, pp. 233-238
-
-
Strautnieks, S.S.1
Bull, L.N.2
Knisely, A.S.3
Kocoshis, S.A.4
Dahl, N.5
Arnell, H.6
Sokal, E.7
Dahan, K.8
Childs, S.9
Ling, V.10
Tanner, M.S.11
Kagalwalla, A.F.12
Nemeth, A.13
Pawlowska, J.14
Baker, A.15
Mieli-Vergani, G.16
Freimer, N.B.17
Gardiner, R.M.18
Thompson, R.J.19
-
46
-
-
0029028792
-
Overlapping substrate specificities and tissue distribution of cytochrome P450 3a and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
-
Wacher V.J., Wu C.-Y., Benet L.Z. Overlapping substrate specificities and tissue distribution of cytochrome P450 3a and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy. Mol. Carcinogen. 13:1995;129-134.
-
(1995)
Mol. Carcinogen.
, vol.13
, pp. 129-134
-
-
Wacher, V.J.1
Wu, C.-Y.2
Benet, L.Z.3
-
47
-
-
0035853057
-
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids
-
Xie W., Radominska-Pandya A., Shi Y., Simon C.M., Nelson M.C., Ong E.S., Waxman D.J., Evans R.M. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proc. Natl. Acad. Sci. USA. 98:2001;3375-3380.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3375-3380
-
-
Xie, W.1
Radominska-Pandya, A.2
Shi, Y.3
Simon, C.M.4
Nelson, M.C.5
Ong, E.S.6
Waxman, D.J.7
Evans, R.M.8
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