Improved siRNA/shRNA functionality by Mismatched duplex

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Wu, Haoquan ^a   Ma, Hongming ^a   Ye, Chunting ^a   Ramirez, Danielle ^a   Chen, Shuiping ^a   Montoya, Jessica ^a   Shankar, Premlata ^a   Wang, Xiaozhong A ^b   Manjunath, N ^a  

^a Paul L Foster School of Medicine   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE PROTEIN; MICRORNA; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; RNA INDUCED SILENCING COMPLEX;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG EFFICACY; DRUG SCREENING; DRUG TARGETING; GENE DUPLICATION; GENE FUNCTION; GENE SILENCING; GENETIC ENGINEERING; RNA STRUCTURE; THERMODYNAMICS; THERMOSTABILITY; VIRUS GENOME; BASE MISPAIRING; CELL STRAIN HEK293; CHEMISTRY; CONFORMATION; GENETICS; HUMAN; METABOLISM; NUCLEOTIDE SEQUENCE;

ARGONAUTE PROTEINS; BASE PAIR MISMATCH; BASE SEQUENCE; CONSERVED SEQUENCE; HEK293 CELLS; HUMANS; NUCLEIC ACID CONFORMATION; RNA, SMALL INTERFERING; RNA-INDUCED SILENCING COMPLEX; THERMODYNAMICS;

EID: 83055164366     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028580     Document Type: Article

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