Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo

Molecular BioSystems

Volumn 6, Issue 5, 2010, Pages 862-870

  Laursen, Maria B ^a,e   Pakula, Malgorzata M ^a   Gao, Shan ^a   Fluiter, Kees ^c   Mook, Olaf R ^c   Baas, Frank ^d   Langklær, Niels ^b   Wengel, Suzy L ^b   Wengel, Jesper ^b   Kjems, Jørgen ^a   Bramsen, Jesper B ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c Macrozyme BV   (Netherlands)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

^e AALBORG UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

SMALL INTERFERING RNA;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG SCREENING; GENETICS; HUMAN; LIVER TUMOR; MOUSE; RNA INTERFERENCE; RNA STABILITY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; HUMANS; LIVER NEOPLASMS; MICE; MOLECULAR STRUCTURE; RNA INTERFERENCE; RNA STABILITY; RNA, SMALL INTERFERING; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MAMMALIA; MUS;

EID: 77952329345     PISSN: 1742206X     EISSN: 17422051     Source Type: Journal    
DOI: 10.1039/b918869j     Document Type: Article

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