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Volumn 9, Issue 1-6, 2011, Pages 211-234

Molecular and genetic basis of childhood cancer

Author keywords

cancer; Childhood; developmental pathways; embryonal tumors; epigenetics; genetic; molecular; molecular diagnostics; pathology; profiling; prognosis; risk stratification; tumor markers

Indexed keywords

ACTIVIN RECEPTOR LIKE KINASE 1; ANTINEOPLASTIC AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIN DEPENDENT KINASE 4; NEUROTROPHIN RECEPTOR; RAPAMYCIN; SURVIVIN; TRANSCRIPTION FACTOR PAX3;

EID: 82955193251     PISSN: 15740153     EISSN: 18758592     Source Type: Journal    
DOI: 10.3233/CBM-2011-0199     Document Type: Article
Times cited : (7)

References (273)
  • 2
    • 0346644386 scopus 로고    scopus 로고
    • Focus on embryonal malignancies
    • J. M. Maris and C. T. Denny, Focus on embryonal malignancies, Cancer Cell 2 (2002), 447-450.
    • (2002) Cancer Cell , vol.2 , pp. 447-450
    • Maris, J.M.1    Denny, C.T.2
  • 3
    • 1842831283 scopus 로고    scopus 로고
    • Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers
    • A. T. Kho, Q. Zhao, Z. Cai, A. J. Butte, J. Y. Kim, S. L. Pomeroy et al. , Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers, Genes Dev 18 (2004), 629-640.
    • (2004) Genes. Dev. , vol.18 , pp. 629-640
    • Kho, A.T.1    Zhao, Q.2    Cai, Z.3    Butte, A.J.4    Kim, J.Y.5    Pomeroy, S.L.6
  • 4
    • 0346307645 scopus 로고    scopus 로고
    • Profiling gene expression in kidney development
    • B. Dekel, Profiling gene expression in kidney development, Nephron Exp Nephrol 95 (2003), e1-6.
    • (2003) Nephron. Exp. Nephrol. , vol.95
    • Dekel, B.1
  • 7
  • 8
    • 0039712065 scopus 로고
    • Mutation and childhood cancer: A probabilistic model for the incidence of retinoblastoma
    • U S A
    • A. G. Knudson, H. W. Jr. , Hethcote andB. W. Brown, Mutation and childhood cancer: a probabilistic model for the incidence of retinoblastoma, Proc Natl Acad Sci U S A 72 (1975), 5116-5120.
    • (1975) Proc. Natl. Acad. Sci. , vol.72 , pp. 5116-5120
    • Knudson, A.G.1    Hethcote Jr., H.W.2    Brown, B.W.3
  • 9
    • 0001736811 scopus 로고    scopus 로고
    • Diagnostic pathology of pediatric malignancies
    • P. A. Pizzo and D. G. Poplack eds Philadelphia: Lippincott Williams and Wilkins
    • T. J. H. Triche and P. H. B. Sorensen, Diagnostic Pathology of Pediatric Malignancies, in: Principles and Practice of Pediatric Oncology, P. A. Pizzo and D. G. Poplack, eds, Philadelphia: Lippincott Williams and Wilkins, 2006, pp. 185-235.
    • (2006) Principles and Practice of Pediatric Oncology , pp. 185-235
    • Triche, T.J.H.1    Sorensen, P.H.B.2
  • 10
    • 0036183742 scopus 로고    scopus 로고
    • Recent advances inwilms tumor genetics
    • J. S. Dome andM. J. Coppes, Recent advances inWilms tumor genetics, Curr Opin Pediatr 14 (2002), 5-11.
    • (2002) Curr. Opin. Pediatr. , vol.14 , pp. 5-11
    • Dome, J.S.1    Coppes, M.J.2
  • 11
    • 0344198135 scopus 로고    scopus 로고
    • Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: Meeting summary
    • R. Gorlick, P. Anderson, I. Andrulis, C. Arndt, G. P. Beardsley, M. Bernstein et al. , Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary, Clin Cancer Res 9 (2003), 5442-5453.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 5442-5453
    • Gorlick, R.1    Anderson, P.2    Andrulis, I.3    Arndt, C.4    Beardsley, G.P.5    Bernstein, M.6
  • 12
    • 19644386697 scopus 로고    scopus 로고
    • EWS-FLI1 fusion protein upregulates critical genes in neural crest development and isresponsible for the observed phenotype of ewings family of tumors
    • S. Hu-Lieskovan, J. Zhang, L. Wu, H. Shimada, D. E. Schofield and T. J. Triche, EWS-FLI1 fusion protein upregulates critical genes in neural crest development and isresponsible for the observed phenotype of Ewing's family of tumors, Cancer Res 65 (2005), 4633-4644.
    • (2005) Cancer Res. , vol.65 , pp. 4633-4644
    • Hu-Lieskovan, S.1    Zhang, J.2    Wu, L.3    Shimada, H.4    Schofield, D.E.5    Triche, T.J.6
  • 13
    • 24944582403 scopus 로고    scopus 로고
    • Expression profiles of osteosarcoma that can predict response to chemotherapy
    • T. K. Man, M. Chintagumpala, J. Visvanathan, J. Shen, L. Perlaky, J. Hicks et al. , Expression profiles of osteosarcoma that can predict response to chemotherapy, Cancer Res 65 (2005), 8142-8150.
    • (2005) Cancer Res. , vol.65 , pp. 8142-8150
    • Man, T.K.1    Chintagumpala, M.2    Visvanathan, J.3    Shen, J.4    Perlaky, L.5    Hicks, J.6
  • 14
    • 51649092873 scopus 로고    scopus 로고
    • Molecular characterization of the pediatric preclinical testing panel
    • G. Neale, X. Su, C. L. Morton, D. Phelps, R. Gorlick, R. B. Lock et al. , Molecular characterization of the pediatric preclinical testing panel, Clin Cancer Res 14 (2008), 4572-4583.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 4572-4583
    • Neale, G.1    Su, X.2    Morton, C.L.3    Phelps, D.4    Gorlick, R.5    Lock, R.B.6
  • 16
    • 0022388606 scopus 로고
    • Association of multiple copies of the nmyc oncogene with rapid progression of neuroblastomas
    • R. C. Seeger, G. M. Brodeur, H. Sather, A. Dalton, S. E. Siegel, K. Y. Wong et al. , Association of multiple copies of the Nmyc oncogene with rapid progression of neuroblastomas, N Engl J Med 313 (1985), 1111-1116.
    • (1985) N. Engl. J. Med. , vol.313 , pp. 1111-1116
    • Seeger, R.C.1    Brodeur, G.M.2    Sather, H.3    Dalton, A.4    Siegel, S.E.5    Wong, K.Y.6
  • 18
    • 0031425266 scopus 로고    scopus 로고
    • Analysis of 1;17 translocation breakpoints in neuroblastoma: Implications for mapping of neuroblastoma genes
    • N. Van Roy, G. Laureys, M. Van Gele, G. Opdenakker, R. Miura, P. van der Drift et al. , Analysis of 1;17 translocation breakpoints in neuroblastoma: implications for mapping of neuroblastoma genes, Eur J Cancer 33 (1997), 1974-1978.
    • (1997) Eur. J. Cancer , vol.33 , pp. 1974-1978
    • Van Roy, N.1    Laureys, G.2    Van Gele, M.3    Opdenakker, G.4    Miura, R.5    Drift Der P.Van6
  • 19
    • 0034598797 scopus 로고    scopus 로고
    • High expression of survivin mapped to 17q25 is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma
    • A. Islam, H. Kageyama, N. Takada, T. Kawamoto, H. Takayasu, E. Isogai et al. , High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma, Oncogene 19 (2000), 617-623.
    • (2000) Oncogene , vol.19 , pp. 617-623
    • Islam, A.1    Kageyama, H.2    Takada, N.3    Kawamoto, T.4    Takayasu, H.5    Isogai, E.6
  • 20
    • 85047695614 scopus 로고    scopus 로고
    • The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23- h1 and nm23-h2
    • M. B. Godfried, M. Veenstra, P. v Sluis, K. Boon, R. v Asperen, M. C. Hermus et al. , The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23- H1 and nm23-H2, Oncogene 21 (2002), 2097-2101.
    • (2002) Oncogene , vol.21 , pp. 2097-2101
    • Godfried, M.B.1    Veenstra, M.2    Sluis, P.V.3    Boon, K.4    Asperen, R.V.5    Hermus Et Al., M.C.6
  • 21
    • 0025979843 scopus 로고
    • Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: A pediatric oncology group study
    • A. T. Look, F. A. Hayes, J. J. Shuster, E. C. Douglass, R. P. Castleberry, L. C. Bowman et al. , Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study, J Clin Oncol 9 (1991), 581-591.
    • (1991) J. Clin. Oncol. , vol.9 , pp. 581-591
    • Look, A.T.1    Hayes, F.A.2    Shuster, J.J.3    Douglass, E.C.4    Castleberry, R.P.5    Bowman, L.C.6
  • 24
    • 20944437124 scopus 로고    scopus 로고
    • Definition and characterization of a region of 1p36. 3 consistently deleted in neuroblastoma
    • P. S. White, P. M. Thompson, T. Gotoh, E. R. Okawa, J. Igarashi, M. Kok et al. , Definition and characterization of a region of 1p36. 3 consistently deleted in neuroblastoma, Oncogene 24 (2005), 2684-2694.
    • (2005) Oncogene , vol.24 , pp. 2684-2694
    • White, P.S.1    Thompson, P.M.2    Gotoh, T.3    Okawa, E.R.4    Igarashi, J.5    Kok, M.6
  • 26
    • 0028107269 scopus 로고
    • Expression and function of TRK-B and BDNF in human neuroblastomas
    • A. Nakagawara, C. G. Azar, N. J. Scavarda and G. M. Brodeur, Expression and function of TRK-B and BDNF in human neuroblastomas, Mol Cell Biol 14 (1994), 759-767.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 759-767
    • Nakagawara, A.1    Azar, C.G.2    Scavarda, N.J.3    Brodeur, G.M.4
  • 27
    • 54049094708 scopus 로고    scopus 로고
    • Identification of ALK as a major familial neuroblastoma predisposition gene
    • Y. P. Mosse,M. Laudenslager, L. Longo, K. A. Cole, A. Wood, E. F. Attiyeh et al. , Identification of ALK as a major familial neuroblastoma predisposition gene, Nature 455 (2008), 930-935.
    • (2008) Nature , vol.455 , pp. 930-935
    • Mossem. Laudenslager, Y.P.1    Longo, L.2    Cole, K.A.3    Wood, A.4    Attiyeh, E.F.5
  • 28
  • 29
    • 54049118823 scopus 로고    scopus 로고
    • Oncogenic mutations of ALK kinase in neuroblastoma
    • Y. Chen, J. Takita, Y. L. Choi, M. Kato, M. Ohira, M. Sanada et al. , Oncogenic mutations of ALK kinase in neuroblastoma, Nature 455 (2008), 971-974.
    • (2008) Nature , vol.455 , pp. 971-974
    • Chen, Y.1    Takita, J.2    Choi, Y.L.3    Kato, M.4    Ohira, M.5    Sanada, M.6
  • 30
    • 54049120220 scopus 로고    scopus 로고
    • Activating mutations in ALK provide a therapeutic target in neuroblastoma
    • R. E. George, T. Sanda, M. Hanna, S. Frohling, W. ,2nd. Luther, J. Zhang et al. , Activating mutations in ALK provide a therapeutic target in neuroblastoma, Nature 455 (2008),975-978.
    • (2008) Nature , vol.455 , pp. 975-978
    • George, R.E.1    Sanda, T.2    Hanna, M.3    Frohling, S.4    Luther II, W.5    Zhang, J.6
  • 31
    • 0037112452 scopus 로고    scopus 로고
    • Evidence for a hereditary neuroblastoma predisposition locus at chromosome 16p12-13
    • J. M. Maris, M. J. Weiss, Y. Mosse, G. Hii, C. Guo, P. S. White et al. , Evidence for a hereditary neuroblastoma predisposition locus at chromosome 16p12-13, Cancer Res 62 (2002), 6651-6658.
    • (2002) Cancer Res. , vol.62 , pp. 6651-6658
    • Maris, J.M.1    Weiss, M.J.2    Mosse, Y.3    Hii, G.4    Guo, C.5    White, P.S.6
  • 33
    • 0033888976 scopus 로고    scopus 로고
    • Strong immunostaining for myogenin in rhabdomyosarcoma is significantly associated with tumors of the alveolar subclass
    • P. Dias, B. Chen, B. Dilday, H. Palmer, H. Hosoi, S. Singh et al. , Strong immunostaining for myogenin in rhabdomyosarcoma is significantly associated with tumors of the alveolar subclass, Am J Pathol 156 (2000), 399-408.
    • (2000) Am. J. Pathol. , vol.156 , pp. 399-408
    • Dias, P.1    Chen, B.2    Dilday, B.3    Palmer, H.4    Hosoi, H.5    Singh, S.6
  • 34
    • 0035031713 scopus 로고    scopus 로고
    • Pathologic classification of rhabdomyosarcomas and correlations with molecular studies
    • D. M. Parham, Pathologic classification of rhabdomyosarcomas and correlations with molecular studies, Mod Pathol 14 (2001), 506-514.
    • (2001) Mod. Pathol. , vol.14 , pp. 506-514
    • Parham, D.M.1
  • 36
    • 0036514765 scopus 로고    scopus 로고
    • Risk assignment in pediatric soft-tissue sarcomas: An evolving molecular classification
    • S. J. Qualman and R. A. Morotti, Risk assignment in pediatric soft-tissue sarcomas: an evolving molecular classification, Curr Oncol Rep 4 (2002), 123-130.
    • (2002) Curr. Oncol. Rep. , vol.4 , pp. 123-130
    • Qualman, S.J.1    Morotti, R.A.2
  • 38
    • 85047698674 scopus 로고
    • Closely linked loci on the long arm of chromosome 13 flank a specific 2;13 translocation breakpoint in childhood rhabdomyosarcoma
    • M. Valentine, E. C. Douglass and A. T. Look, Closely linked loci on the long arm of chromosome 13 flank a specific 2;13 translocation breakpoint in childhood rhabdomyosarcoma, Cytogenet Cell Genet 52 (1989), 128-132.
    • (1989) Cytogenet Cell Genet , vol.52 , pp. 128-132
    • Valentine, M.1    Douglass, E.C.2    Look, A.T.3
  • 39
    • 0027534945 scopus 로고
    • Rearrangement of the pax3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma
    • F. G. Barr, N. Galili, J. Holick, J. A. Biegel, G. Rovera and B. S. Emanuel, Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma, Nat Genet 3 (1993), 113-117.
    • (1993) Nat. Genet. , vol.3 , pp. 113-117
    • Barr, F.G.1    Galili, N.2    Holick, J.3    Biegel, J.A.4    Rovera, G.5    Emanuel, B.S.6
  • 42
    • 0028364374 scopus 로고
    • Fusion of PAX7 to FKHR by the variant t 1;13 p36;q14 translocation in alveolar rhabdomyosarcoma
    • R. J. Davis, C. M. D'Cruz, M. A. Lovell, J. A. Biegel and F. G. Barr, Fusion of PAX7 to FKHR by the variant t(1;13) (p36;q14) translocation in alveolar rhabdomyosarcoma, Cancer Res 54 (1994), 2869-2872.
    • (1994) Cancer Res. , vol.54 , pp. 2869-2872
    • Davis, R.J.1    D'cruz, C.M.2    Lovell, M.A.3    Biegel, J.A.4    Barr, F.G.5
  • 43
    • 4143150844 scopus 로고    scopus 로고
    • Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t2;2 q35;p23 translocation fusing pax3 to ncoa1
    • M. Wachtel, M. Dettling, E. Koscielniak, S. Stegmaier, J. Treuner, K. Simon-Klingenstein et al. , Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1, Cancer Res 64 (2004), 5539-5545.
    • (2004) Cancer Res. , vol.64 , pp. 5539-5545
    • Wachtel, M.1    Dettling, M.2    Koscielniak, E.3    Stegmaier, S.4    Treuner, J.5    Simon-Klingenstein, K.6
  • 44
    • 18244374534 scopus 로고    scopus 로고
    • Genomic gains and losses are similar in genetic and histologic subsets of rhabdomyosarcomawhereas amplification predominates in embryonal with anaplasia and alveolar subtypes
    • J. A. Bridge, J. Liu, S. J. Qualman, R. Suijkerbuijk, G. Wenger, J. Zhang et al. , Genomic gains and losses are similar in genetic and histologic subsets of rhabdomyosarcoma,whereas amplification predominates in embryonal with anaplasia and alveolar subtypes, Genes Chromosomes Cancer 33 (2002), 310-321.
    • (2002) Genes Chromosomes Cancer , vol.33 , pp. 310-321
    • Bridge, J.A.1    Liu, J.2    Qualman, S.J.3    Suijkerbuijk, R.4    Wenger, G.5    Zhang, J.6
  • 46
    • 0034080846 scopus 로고    scopus 로고
    • Cytogenetic and molecular genetic techniques as adjunctive approaches in the diagnosis of bone and soft tissue tumors
    • J. A. Bridge and A. A. Sandberg, Cytogenetic and molecular genetic techniques as adjunctive approaches in the diagnosis of bone and soft tissue tumors, Skeletal Radiol 29 (2000), 249-258.
    • (2000) Skeletal. Radiol. , vol.29 , pp. 249-258
    • Bridge, J.A.1    Sandberg, A.A.2
  • 48
    • 0033539498 scopus 로고    scopus 로고
    • Cdna microarrays detect activation of a myogenic transcription program by the pax3-fkhr fusion oncogene
    • USA
    • J. Khan,M. L. Bittner, L. H. Saal, U. Teichmann, D. O. Azorsa, G. C. Gooden et al. , cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene, Proc NatlAcad SciUSA 96 (1999), 13264-13269.
    • (1999) Proc. Natl. Acad. Sci. , vol.96 , pp. 13264-13269
    • Khan, J.1    Bittner, M.L.2    Saal, L.H.3    Teichmann, U.4    Azorsa, D.O.5    Gooden, G.C.6
  • 49
    • 0029980113 scopus 로고    scopus 로고
    • Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma
    • U S A
    • J. L. Bennicelli, R. H. Edwards and F. G. Barr, Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma, Proc Natl Acad Sci U S A 93 (1996), 5455-5459.
    • (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 5455-5459
    • Bennicelli, J.L.1    Edwards, R.H.2    Barr, F.G.3
  • 51
    • 15744400937 scopus 로고    scopus 로고
    • Novel genes possibly relevant for molecular diagnosis or therapy of human rhabdomyosarcoma detected by genomic expression profiling
    • S. Bortoluzzi, A. Bisognin, C. Romualdi and G. A. Danieli, Novel genes, possibly relevant for molecular diagnosis or therapy of human rhabdomyosarcoma, detected by genomic expression profiling, Gene 348 (2005), 65-71.
    • (2005) Gene. , vol.348 , pp. 65-71
    • Bortoluzzi, S.1    Bisognin, A.2    Romualdi, C.3    Danieli, G.A.4
  • 52
    • 0025054481 scopus 로고
    • Myod induces growth arrest independent of differentiation in normal and transformed cells
    • U S A
    • M. Crescenzi, T. P. Fleming, A. B. Lassar, H. Weintraub and S. A. Aaronson, MyoD induces growth arrest independent of differentiation in normal and transformed cells, Proc Natl Acad Sci U S A 87 (1990), 8442-8446.
    • (1990) Proc. Natl. Acad. Sci. , vol.87 , pp. 8442-8446
    • Crescenzi, M.1    Fleming, T.P.2    Lassar, A.B.3    Weintraub, H.4    Aaronson, S.A.5
  • 53
    • 0025277030 scopus 로고
    • Cell proliferation inhibited by myod1 independently of myogenic differentiation
    • V. Sorrentino, R. Pepperkok, R. L. Davis, W. Ansorge and L. Philipson, Cell proliferation inhibited by MyoD1 independently of myogenic differentiation, Nature 345 (1990), 813-815.
    • (1990) Nature , vol.345 , pp. 813-815
    • Sorrentino, V.1    Pepperkok, R.2    Davis, R.L.3    Ansorge, W.4    Philipson, L.5
  • 55
    • 0032417124 scopus 로고    scopus 로고
    • N-myc gene amplification in rhabdomyosarcoma detected by fluorescence in situ hybridization: Its correlation with histologic features
    • Y. Hachitanda, S. Toyoshima, K. Akazawa and M. Tsuneyoshi, N-myc gene amplification in rhabdomyosarcoma detected by fluorescence in situ hybridization: its correlation with histologic features, Mod Pathol 11 (1998), 1222-1227.
    • (1998) Mod. Pathol. , vol.11 , pp. 1222-1227
    • Hachitanda, Y.1    Toyoshima, S.2    Akazawa, K.3    Tsuneyoshi, M.4
  • 57
    • 0029929274 scopus 로고    scopus 로고
    • Analysis of cyclin-dependent kinase inhibitor genes cdkn2a cdkn2b andcdkn2c in childhood rhabdomyosarcoma
    • A. Iolascon, M. F. Faienza, B. Coppola, A. Rosolen, G. Basso, F. Della Ragione et al. , Analysis of cyclin-dependent kinase inhibitor genes (CDKN2A,CDKN2B, andCDKN2C) in childhood rhabdomyosarcoma, Genes Chromosomes Cancer 15 (1996), 217-222.
    • (1996) Genes Chromosomes Cancer , vol.15 , pp. 217-222
    • Iolascon, A.1    Faienza, M.F.2    Coppola, B.3    Rosolen, A.4    Basso, G.5    Della Ragione, F.6
  • 58
    • 20044391414 scopus 로고    scopus 로고
    • Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype
    • D. Williamson, Y. J. Lu, T. Gordon, R. Sciot, A. Kelsey, C. Fisher et al. , Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype, J Clin Oncol 23 (2005), 880-888.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 880-888
    • Williamson, D.1    Lu, Y.J.2    Gordon, T.3    Sciot, R.4    Kelsey, A.5    Fisher, C.6
  • 59
    • 10044288449 scopus 로고    scopus 로고
    • Rhabdomyosarcoma: Value of myogenin expression analysis and molecular testing in diagnosing the alveolar subtype: An analysis of 109 paraffin-embedded specimens
    • I. Hostein, M. Andraud-Fregeville, L. Guillou, M. J. Terrier- Lacombe, C. Deminiere, D. Ranchere et al. , Rhabdomyosarcoma: value of myogenin expression analysis and molecular testing in diagnosing the alveolar subtype: an analysis of 109 paraffin-embedded specimens, Cancer 101 (2004), 2817-2824.
    • (2004) Cancer , vol.101 , pp. 2817-2824
    • Hostein, I.1    Andraud-Fregeville, M.2    Guillou, L.3    Terrier- Lacombe, M.J.4    Deminiere, C.5    Ranchere, D.6
  • 60
    • 53449087711 scopus 로고    scopus 로고
    • Diffuse myogenin expression by immunohistochemistry is an independent marker of poor survival in pediatric rhabdomyosarcoma: A tissue microarray study of 71 primary tumors including correlation with molecular phenotype
    • A. Heerema-McKenney, L. C. Wijnaendts, J. F. Pulliam, D. Lopez-Terrada, J. K. McKenney, S. Zhu et al. , Diffuse myogenin expression by immunohistochemistry is an independent marker of poor survival in pediatric rhabdomyosarcoma: a tissue microarray study of 71 primary tumors including correlation with molecular phenotype, Am J Surg Pathol 32 (2008), 1513-1522.
    • (2008) Am. J. Surg. Pathol. , vol.32 , pp. 1513-1522
    • Heerema-Mckenney, A.1    Wijnaendts, L.C.2    Pulliam, J.F.3    Lopez-Terrada, D.4    McKenney, J.K.5    Zhu, S.6
  • 61
    • 0036605806 scopus 로고    scopus 로고
    • Pax3-fkhr and pax7- fkhr gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: A report from the children's oncology group
    • P. H. Sorensen, J. C. Lynch, S. J. Qualman, R. Tirabosco, J. F. Lim, H. M. Maurer et al. , PAX3-FKHR and PAX7- FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children's oncology group, J Clin Oncol 20 (2002), 2672-2679.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 2672-2679
    • Sorensen, P.H.1    Lynch, J.C.2    Qualman, S.J.3    Tirabosco, R.4    Lim, J.F.5    Maurer, H.M.6
  • 62
    • 0037102443 scopus 로고    scopus 로고
    • Genetic heterogeneity in the alveolar rhabdomyosarcoma subset without typical gene fusions
    • F. G. Barr, S. J. Qualman, M. H. Macris, N. Melnyk, E. R. Lawlor, D. M. Strzelecki et al. , Genetic heterogeneity in the alveolar rhabdomyosarcoma subset without typical gene fusions, Cancer Res 62 (2002), 4704-4710.
    • (2002) Cancer Res. , vol.62 , pp. 4704-4710
    • Barr, F.G.1    Qualman, S.J.2    MacRis, M.H.3    Melnyk, N.4    Lawlor, E.R.5    Strzelecki, D.M.6
  • 63
    • 0028888439 scopus 로고
    • Molecular assays for chromosomal translocations in the diagnosis of pediatric soft tissue sarcomas
    • F. G. Barr, J. Chatten, C. M. D'Cruz, A. E. Wilson, L. E. Nauta, L. M. Nycum et al. , Molecular assays for chromosomal translocations in the diagnosis of pediatric soft tissue sarcomas, Jama 273 (1995), 553-557.
    • (1995) Jama , vol.273 , pp. 553-557
    • Barr, F.G.1    Chatten, J.2    D'cruz, C.M.3    Wilson, A.E.4    Nauta, L.E.5    Nycum, L.M.6
  • 64
    • 0028928079 scopus 로고
    • Detection of the t 2;13 q35;q14 and pax3-fkhr fusion in alveolar rhabdomyosarcoma by fluorescence in situ hybridization
    • J. A. Biegel, L. M. Nycum, V. Valentine, F. G. Barr and D. N. Shapiro, Detection of the t(2;13)(q35;q14) and PAX3-FKHR fusion in alveolar rhabdomyosarcoma by fluorescence in situ hybridization, Genes Chromosomes Cancer 12 (1995), 186-192.
    • (1995) Genes Chromosomes Cancer , vol.12 , pp. 186-192
    • Biegel, J.A.1    Nycum, L.M.2    Valentine, V.3    Barr, F.G.4    Shapiro, D.N.5
  • 65
    • 0035105525 scopus 로고    scopus 로고
    • Use of reverse transcriptase polymerase chain reaction for diagnosis and staging of alveolar rhabdomyosarcoma ewing sarcoma family of tumors and desmoplastic small round cell tumor
    • U. H. Athale, S. A. Shurtleff, J. J. Jenkins, C. A. Poquette, M. Tan, J. R. Downing et al. , Use of reverse transcriptase polymerase chain reaction for diagnosis and staging of alveolar rhabdomyosarcoma, Ewing sarcoma family of tumors, and desmoplastic small round cell tumor, J Pediatr Hematol Oncol 23 (2001), 99-104.
    • (2001) J. Pediatr. Hematol. Oncol. , vol.23 , pp. 99-104
    • Athale, U.H.1    Shurtleff, S.A.2    Jenkins, J.J.3    Poquette, C.A.4    Tan, M.5    Downing, J.R.6
  • 67
    • 0024599574 scopus 로고
    • Complex karyotypes in a series of pediatric osteosarcomas
    • J. A. Biegel, R. B. Womer and B. S. Emanuel, Complex karyotypes in a series of pediatric osteosarcomas, Cancer Genet Cytogenet 38 (1989), 89-100.
    • (1989) Cancer Genet. Cytogenet. , vol.38 , pp. 89-100
    • Biegel, J.A.1    Womer, R.B.2    Emanuel, B.S.3
  • 69
    • 0027939487 scopus 로고
    • Cytogenetic aberrations in osteosarcomas nonrandom deletions rings and double-minute chromosomes
    • J. A. Fletcher, M. C. Gebhardt and H. P. Kozakewich, Cytogenetic aberrations in osteosarcomas. Nonrandom deletions, rings, and double-minute chromosomes, Cancer Genet Cytogenet 77 (1994), 81-88.
    • (1994) Cancer Genet. Cytogenet. , vol.77 , pp. 81-88
    • Fletcher, J.A.1    Gebhardt, M.C.2    Kozakewich, H.P.3
  • 71
    • 0042745572 scopus 로고    scopus 로고
    • Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: Osteosarcoma and related tumors
    • A. A. Sandberg and J. A. Bridge, Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: osteosarcoma and related tumors, Cancer Genet Cytogenet 145 (2003), 1-30.
    • (2003) Cancer Genet Cytogenet , vol.145 , pp. 1-30
    • Sandberg, A.A.1    Bridge, J.A.2
  • 73
    • 4344633830 scopus 로고    scopus 로고
    • High-resolution cDNA microarray CGH mapping of genomic imbalances in osteosarcoma using formalinfixed paraffin-embedded tissue
    • M. Zielenska, P. Marrano, P. Thorner, J. Pei, B. Beheshti, M. Ho et al. , High-resolution cDNA microarray CGH mapping of genomic imbalances in osteosarcoma using formalinfixed paraffin-embedded tissue, Cytogenet Genome Res 107 (2004), 77-82.
    • (2004) Cytogenet. Genome. Res. , vol.107 , pp. 77-82
    • Zielenska, M.1    Marrano, P.2    Thorner, P.3    Pei, J.4    Beheshti, B.5    Ho, M.6
  • 74
    • 0035918534 scopus 로고    scopus 로고
    • Presence of telomerase activity in different musculoskeletal tumor histotypes and correlation with aggressiveness
    • L. Sangiorgi, G. A. Gobbi, E. Lucarelli, S. M. Sartorio, M. Mordenti, I. Ghedini et al. , Presence of telomerase activity in different musculoskeletal tumor histotypes and correlation with aggressiveness, Int J Cancer 95 (2001), 156-161.
    • (2001) Int. J. Cancer , vol.95 , pp. 156-161
    • Sangiorgi, L.1    Gobbi, G.A.2    Lucarelli, E.3    Sartorio, S.M.4    Mordenti, M.5    Ghedini, I.6
  • 75
    • 0344837710 scopus 로고    scopus 로고
    • Absence of a telomere maintenance mechanism as a favorable prognostic factor in patients with osteosarcoma
    • G. A. Ulaner, H. Y. Huang, J. Otero, Z. Zhao, L. Ben-Porat, J. M. Satagopan et al. , Absence of a telomere maintenance mechanism as a favorable prognostic factor in patients with osteosarcoma, Cancer Res 63 (2003), 1759-1763.
    • (2003) Cancer Res. , vol.63 , pp. 1759-1763
    • Ulaner, G.A.1    Huang, H.Y.2    Otero, J.3    Zhao, Z.4    Ben-Porat, L.5    Satagopan, J.M.6
  • 76
    • 0027978368 scopus 로고
    • Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: Preliminary mapping of the amplicons shows preferential involvement of CDK4 SAS and MDM2
    • G. R. J. Reifenberger, K. Ichimura, P. S. Meltzer and V. P. Collins, Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2, Cancer Res 54 (1994), 4299-4303.
    • (1994) Cancer Res. , vol.54 , pp. 4299-4303
    • Reifenberger, G.R.J.1    Ichimura, K.2    Meltzer, P.S.3    Collins, V.P.4
  • 78
    • 0022402666 scopus 로고
    • Osteosarcoma and retinoblastoma: A shared chromosomal mechanism revealing recessive predisposition
    • U S A
    • M. F. Hansen, A. Koufos, B. L. Gallie, R. A. Phillips, O. Fodstad, A. Brogger et al. , Osteosarcoma and retinoblastoma: a shared chromosomal mechanism revealing recessive predisposition, Proc Natl Acad Sci U S A 82 (1985), 6216-6220.
    • (1985) Proc. Natl. Acad. Sci. , vol.82 , pp. 6216-6220
    • Hansen, M.F.1    Koufos, A.2    Gallie, B.L.3    Phillips, R.A.4    Fodstad, O.5    Brogger, A.6
  • 79
    • 0022506980 scopus 로고
    • A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
    • S. H. Friend, R. Bernards, S. Rogelj, R. A. Weinberg, J. M. Rapaport, D. M. Albert et al. , A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma, Nature 323 (1986), 643-646.
    • (1986) Nature , vol.323 , pp. 643-646
    • Friend, S.H.1    Bernards, R.2    Rogelj, S.3    Weinberg, R.A.4    Rapaport, J.M.5    Albert, D.M.6
  • 80
    • 0023777950 scopus 로고
    • Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcoma
    • J. Toguchida, K. Ishizaki, M. S. Sasaki, M. Ikenaga, M. Sugimoto, Y. Kotoura et al. , Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcoma, Cancer Res 48 (1988), 3939-3943.
    • (1988) Cancer Res. , vol.48 , pp. 3939-3943
    • Toguchida, J.1    Ishizaki, K.2    Sasaki, M.S.3    Ikenaga, M.4    Sugimoto, M.5    Kotoura, Y.6
  • 85
    • 0026776432 scopus 로고
    • Tumor suppressor gene Rb and p53 mutations in osteosarcoma
    • ix- x.
    • R. R. Schreck, Tumor suppressor gene (Rb and p53) mutations in osteosarcoma, Pediatr Hematol Oncol 9 (1992), ix- x.
    • (1992) Pediatr. Hematol. Oncol. , vol.9
    • Schreck, R.R.1
  • 86
    • 0141705379 scopus 로고    scopus 로고
    • The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability
    • U S A
    • M. Overholtzer, P. H. Rao, R. Favis, R. Lu, M. B. Elowitz, F. Barany et al. , The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability, Proc Natl Acad Sci U S A 100 (2003), 11547-11552.
    • (2003) Proc. Natl. Acad. Sci. , vol.100 , pp. 11547-11552
    • Overholtzer, M.1    Rao, P.H.2    Favis, R.3    Lu, R.4    Elowitz, M.B.5    Barany, F.6
  • 89
    • 2442471534 scopus 로고    scopus 로고
    • Aberrations of p16INK4A p14ARF and p15INK4B genes in pediatric solid tumors
    • K. Obana, H. W. Yang, H. Y. Piao, T. Taki, K. Hashizume, R. Hanada et al. , Aberrations of p16INK4A, p14ARF and p15INK4B genes in pediatric solid tumors, Int J Oncol 23 (2003), 1151-1157.
    • (2003) Int. J. Oncol. , vol.23 , pp. 1151-1157
    • Obana, K.1    Yang, H.W.2    Piao, H.Y.3    Taki, T.4    Hashizume, K.5    Hanada, R.6
  • 91
    • 0034661248 scopus 로고    scopus 로고
    • Analysis of the p16ink4 p14arf p15 tp53 and mdm2 genes and their prognostic implications in osteosarcoma and ewing sarcoma
    • T. Tsuchiya, K. Sekine, S. Hinohara, T. Namiki, T. Nobori and Y. Kaneko, Analysis of the p16INK4, p14ARF, p15, TP53, and MDM2 genes and their prognostic implications in osteosarcoma and Ewing sarcoma, Cancer Genet Cytogenet 120 (2000), 91-98.
    • (2000) Cancer Genet. Cytogenet. , vol.120 , pp. 91-98
    • Tsuchiya, T.1    Sekine, K.2    Hinohara, S.3    Namiki, T.4    Nobori, T.5    Kaneko, Y.6
  • 92
    • 0036211680 scopus 로고    scopus 로고
    • Alterations in the ink4a/arf locus and their effects on the growth of human osteosarcoma cell lines
    • Y. B. Park,M. J. Park, K. Kimura, K. Shimizu, S. H. Lee and J. Yokota, Alterations in the INK4a/ARF locus and their effects on the growth of human osteosarcoma cell lines, Cancer Genet Cytogenet 133 (2002), 105-111.
    • (2002) Cancer Genet. Cytogenet. , vol.133 , pp. 105-111
    • Park, Y.B.1    Park, M.J.2    Kimura, K.3    Shimizu, K.4    Lee, S.H.5    Yokota, J.6
  • 93
    • 0034841867 scopus 로고    scopus 로고
    • Aberrant expression of tumor suppressor proteins in the Ewing family of tumors
    • A. Maitra, H. Roberts, A. G. Weinberg and J. Geradts, Aberrant expression of tumor suppressor proteins in the Ewing family of tumors, Arch Pathol Lab Med 125 (2001), 1207-1212.
    • (2001) Arch. Pathol. Lab. Med. , vol.125 , pp. 1207-1212
    • Maitra, A.1    Roberts, H.2    Weinberg, A.G.3    Geradts, J.4
  • 94
    • 0031783711 scopus 로고    scopus 로고
    • C-myc and c-fos in human osteosarcoma: Prognostic value of mrna and protein expression
    • G. Gamberi, M. S. Benassi, T. Bohling, P. Ragazzini, L. Molendini, M. R. Sollazzo et al. , C-myc and c-fos in human osteosarcoma: prognostic value of mRNA and protein expression, Oncology 55 (1998), 556-563.
    • (1998) Oncology , vol.55 , pp. 556-563
    • Gamberi, G.1    Benassi, M.S.2    Bohling, T.3    Ragazzini, P.4    Molendini, L.5    Sollazzo, M.R.6
  • 98
    • 0141889935 scopus 로고    scopus 로고
    • High-resolution mapping of amplifications and deletions in pediatric osteosarcoma by use ofcghanalysis of cdna microarrays
    • J. A. Squire, J. Pei, P. Marrano, B. Beheshti, J. Bayani, G. Lim et al. , High-resolution mapping of amplifications and deletions in pediatric osteosarcoma by use ofCGHanalysis of cDNA microarrays, Genes Chromosomes Cancer 38 (2003), 215-225.
    • (2003) Genes Chromosomes Cancer , vol.38 , pp. 215-225
    • Squire, J.A.1    Pei, J.2    Marrano, P.3    Beheshti, B.4    Bayani, J.5    Lim, G.6
  • 99
    • 0345304776 scopus 로고    scopus 로고
    • Biological properties and gene expression associated with metastatic potential of human osteosarcoma
    • T. Nakano, M. Tani, Y. Ishibashi, K. Kimura, Y. B. Park, N. Imaizumi et al. , Biological properties and gene expression associated with metastatic potential of human osteosarcoma, Clin Exp Metastasis 20 (2003), 665-674.
    • (2003) Clin. Exp. Metastasis , vol.20 , pp. 665-674
    • Nakano, T.1    Tani, M.2    Ishibashi, Y.3    Kimura, K.4    Park, Y.B.5    Imaizumi, N.6
  • 104
    • 0021262110 scopus 로고
    • Translocation involving chromosome 22 in ewings sarcoma a cytogenetic study of four fresh tumors
    • A. Aurias, C. Rimbaut, D. Buffe, J. M. Zucker and A. Mazabraud, Translocation involving chromosome 22 in Ewing's sarcoma. A cytogenetic study of four fresh tumors, Cancer Genet Cytogenet 12 (1984), 21-25.
    • (1984) Cancer Genet. Cytogenet. , vol.12 , pp. 21-25
    • Aurias, A.1    Rimbaut, C.2    Buffe, D.3    Zucker, J.M.4    Mazabraud, A.5
  • 105
    • 0021252642 scopus 로고
    • Chromosome study of ewing's sarcoma es cell lines consistency of a reciprocal translocation t 11;22 q24;q12
    • C. Turc-Carel, I. Philip, M. P. Berger, T. Philip and G. M. Lenoir, Chromosome study of Ewing's sarcoma (ES) cell lines. Consistency of a reciprocal translocation t(11;22) (q24;q12), Cancer Genet Cytogenet 12 (1984), 1-19.
    • (1984) Cancer Genet Cytogenet , vol.12 , pp. 1-19
    • Turc-Carel, C.1    Philip, I.2    Berger, M.P.3    Philip, T.4    Lenoir, G.M.5
  • 107
    • 0028307384 scopus 로고
    • A second ewings sarcoma translocation t 21;22 fuses the ews gene to another etsfamily transcription factor erg
    • P. H. Sorensen, S. L. Lessnick, D. Lopez-Terrada, X. F. Liu, T. J. Triche and C. T. Denny, A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETSfamily transcription factor, ERG, Nat Genet 6 (1994), 146-151.
    • (1994) Nat. Genet. , vol.6 , pp. 146-151
    • Sorensen, P.H.1    Lessnick, S.L.2    Lopez-Terrada, D.3    Liu, X.F.4    Triche, T.J.5    Denny, C.T.6
  • 108
    • 0033668831 scopus 로고    scopus 로고
    • Updates on cytogenetics and molecular genetics of bone and soft tissue tumors: Ewing sarcoma and peripheral primitive neuroectodermal tumors
    • A. A. Sandberg and J. A. Bridge, Updates on cytogenetics and molecular genetics of bone and soft tissue tumors: Ewing sarcoma and peripheral primitive neuroectodermal tumors, Cancer Genet Cytogenet 123 (2000), 1-26.
    • (2000) Cancer Genet. Cytogenet. , vol.123 , pp. 1-26
    • Sandberg, A.A.1    Bridge, J.A.2
  • 110
    • 0026686674 scopus 로고
    • Gene fusion with an ets dna-binding domain caused by chromosome translocation in human tumours
    • O. Delattre, J. Zucman, B. Plougastel, C. Desmaze, T. Melot, M. Peter et al. , Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours, Nature 359 (1992), 162-165.
    • (1992) Nature , vol.359 , pp. 162-165
    • Delattre, O.1    Zucman, J.2    Plougastel, B.3    Desmaze, C.4    Melot, T.5    Peter, M.6
  • 111
    • 0026746009 scopus 로고
    • Cloning and characterization of the Ewing's sarcoma and peripheral neuroepithelioma t 11;22 translocation breakpoints
    • J. Zucman, O. Delattre, C. Desmaze, B. Plougastel, I. Joubert, T. Melot et al. , Cloning and characterization of the Ewing's sarcoma and peripheral neuroepithelioma t(11;22) translocation breakpoints, Genes Chromosomes Cancer 5 (1992), 71-277.
    • (1992) Genes. Chromosomes Cancer , vol.5 , pp. 71-277
    • Zucman, J.1    Delattre, O.2    Desmaze, C.3    Plougastel, B.4    Joubert, I.5    Melot, T.6
  • 112
    • 0027230568 scopus 로고
    • Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the dna-binding domain encoded by fli1 for transformation
    • U S A
    • W. A. May, M. L. Gishizky, S. L. Lessnick, L. B. Lunsford, B. C. Lewis, O. Delattre et al. , Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation, Proc Natl Acad Sci U S A 90 (1993), 5752-5756.
    • (1993) Proc. Natl. Acad. Sci. , vol.90 , pp. 5752-5756
    • May, W.A.1    Gishizky, M.L.2    Lessnick, S.L.3    Lunsford, L.B.4    Lewis, B.C.5    Delattre, O.6
  • 113
    • 0027438827 scopus 로고
    • Combinatorial generation of variable fusion proteins in the ewing family of tumours
    • J. Zucman, T. Melot, C. Desmaze, J. Ghysdael, B. Plougastel, M. Peter et al. , Combinatorial generation of variable fusion proteins in the Ewing family of tumours, Embo J 12 (1993), 4481-4487.
    • (1993) Embo. J. , vol.12 , pp. 4481-4487
    • Zucman, J.1    Melot, T.2    Desmaze, C.3    Ghysdael, J.4    Plougastel, B.5    Peter, M.6
  • 114
    • 0028903089 scopus 로고
    • A variant ewings sarcoma translocation 7;22 fuses the ews gene to the ets gene etv1
    • I. S. Jeon, J. N. Davis, B. S. Braun, J. E. Sublett, M. F. Roussel, C. T. Denny et al. , A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1, Oncogene 10 (1995), 1229-1234.
    • (1995) Oncogene , vol.10 , pp. 1229-1234
    • Jeon, I.S.1    Davis, J.N.2    Braun, B.S.3    Sublett, J.E.4    Roussel, M.F.5    Denny, C.T.6
  • 115
    • 34548775691 scopus 로고    scopus 로고
    • Ewing sarcoma with novel translocation t2;16 producing an in-frame fusion of fus and fev
    • T. L. Ng, M. J. O'Sullivan, C. J. Pallen, M. Hayes, P. W. Clarkson, M. Winstanley et al. , Ewing sarcoma with novel translocation t(2;16) producing an in-frame fusion of FUS and FEV, J Mol Diagn 9 (2007), 459-463.
    • (2007) J. Mol. Diagn. , vol.9 , pp. 459-463
    • Ng, T.L.1    Van, M.J.O.2    Pallen, C.J.3    Hayes, M.4    Clarkson, P.W.5    Winstanley, M.6
  • 117
    • 34548806398 scopus 로고    scopus 로고
    • Undifferentiated small round cell sarcomas with rare ews gene fusions: Identification of a novel ewssp3 fusion and of additional cases with the ews-etv1 and ews-fev fusions
    • L. Wang, R. Bhargava, T. Zheng, L. Wexler, M. H. Collins, D. Roulston et al. , Undifferentiated small round cell sarcomas with rare EWS gene fusions: identification of a novel EWSSP3 fusion and of additional cases with the EWS-ETV1 and EWS-FEV fusions, J Mol Diagn 9 (2007), 498-509.
    • (2007) J. Mol. Diagn. , vol.9 , pp. 498-509
    • Wang, L.1    Bhargava, R.2    Zheng, T.3    Wexler, L.4    Collins, M.H.5    Roulston, D.6
  • 119
    • 0035866778 scopus 로고    scopus 로고
    • The Ewing's sarcoma gene product functions as a transcriptional activator
    • K. L. Rossow and R. Janknecht, The Ewing's sarcoma gene product functions as a transcriptional activator, Cancer Res 61 (2001), 2690-2695.
    • (2001) Cancer Res. , vol.61 , pp. 2690-2695
    • Rossow, K.L.1    Janknecht, R.2
  • 120
    • 0035839938 scopus 로고    scopus 로고
    • Biology of ews/ets fusions in ewing's family tumors
    • A. Arvand and C. T. Denny, Biology of EWS/ETS fusions in Ewing's family tumors, Oncogene 20 (2001), 5747-5754.
    • (2001) Oncogene. , vol.20 , pp. 5747-5754
    • Arvand, A.1    Denny, C.T.2
  • 121
    • 0036560740 scopus 로고    scopus 로고
    • The Ewings sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts
    • S. L. Lessnick, C. S. Dacwag and T. R. Golub, The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts, Cancer Cell 1 (2002), 393-401.
    • (2002) Cancer Cell , vol.1 , pp. 393-401
    • Lessnick, S.L.1    Dacwag, C.S.2    Golub, T.R.3
  • 122
    • 0037569709 scopus 로고    scopus 로고
    • PIM3 proto-oncogene kinase is a common transcriptional target of divergent ews/ets oncoproteins
    • B. Deneen, S. M. Welford, T. Ho, F. Hernandez, I. Kurland and C. T. Denny, PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins, Mol Cell Biol 23 (2003), 3897-3908.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 3897-3908
    • Deneen, B.1    Welford, S.M.2    Ho, T.3    Hernandez, F.4    Kurland, I.5    Denny, C.T.6
  • 125
    • 20044367805 scopus 로고    scopus 로고
    • Ewing sarcomas with p53 mutation or p16/p14ARF homozygous deletion: A highly lethal subset associated with poor chemoresponse
    • H. Y. Huang, P. B. Illei, Z. Zhao, M. Mazumdar, A. G. Huvos, J. H. Healey et al. , Ewing sarcomas with p53 mutation or p16/p14ARF homozygous deletion: a highly lethal subset associated with poor chemoresponse, J Clin Oncol 23 (2005), 548-558.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 548-558
    • Huang, H.Y.1    Illei, P.B.2    Zhao, Z.3    Mazumdar, M.4    Huvos, A.G.5    Healey, J.H.6
  • 126
    • 8544237013 scopus 로고    scopus 로고
    • DNA microarrays reveal relationship of Ewing family tumors to both endothelial and fetal neural crest-derived cells and define novel targets
    • M. S. Staege, C. Hutter, I. Neumann, S. Foja, U. E. Hattenhorst, G. Hansen et al. , DNA microarrays reveal relationship of Ewing family tumors to both endothelial and fetal neural crest-derived cells and define novel targets, Cancer Res 64 (2004), 8213-8221.
    • (2004) Cancer Res. , vol.64 , pp. 8213-8221
    • Staege, M.S.1    Hutter, C.2    Neumann, I.3    Foja, S.4    Hattenhorst, U.E.5    Hansen, G.6
  • 127
    • 0036517835 scopus 로고    scopus 로고
    • Expression analysis of pediatric solid tumor cell lines using oligonucleotide microarrays
    • D. H. Wai, K. L. Schaefer, A. Schramm, E. Korsching, F. Van Valen, T. Ozaki et al. , Expression analysis of pediatric solid tumor cell lines using oligonucleotide microarrays, Int J Oncol 20 (2002), 441-451.
    • (2002) Int. J. Oncol. , vol.20 , pp. 441-451
    • Wai, D.H.1    Schaefer, K.L.2    Schramm, A.3    Korsching, E.4    Van Valen, F.5    Ozaki, T.6
  • 128
    • 10644251887 scopus 로고    scopus 로고
    • Prediction of high risk Ewings sarcoma by gene expression profiling
    • A. Ohali, S. Avigad, R. Zaizov, R. Ophir, S. Horn-Saban, I. J. Cohen et al. , Prediction of high risk Ewing's sarcoma by gene expression profiling, Oncogene 23 (2004), 8997-9006.
    • (2004) Oncogene. , vol.23 , pp. 8997-9006
    • Ohali, A.1    Avigad, S.2    Zaizov, R.3    Ophir, R.4    Horn-Saban, S.5    Cohen, I.J.6
  • 129
    • 0027365309 scopus 로고
    • Mutations of the p53 gene are involved in Ewings sarcomas but not in neuroblastomas
    • H. Komuro, Y. Hayashi, M. Kawamura, K. Hayashi, Y. Kaneko, S. Kamoshita et al. , Mutations of the p53 gene are involved in Ewing's sarcomas but not in neuroblastomas, Cancer Res 53 (1993), 5284-5288.
    • (1993) Cancer Res. , vol.53 , pp. 5284-5288
    • Komuro, H.1    Hayashi, Y.2    Kawamura, M.3    Hayashi, K.4    Kaneko, Y.5    Kamoshita, S.6
  • 131
    • 0030060750 scopus 로고    scopus 로고
    • Molecular and immunohistochemical identification of p53 alterations in bone and soft tissue sarcomas
    • S. Mousses, L. McAuley, R. S. Bell, R. Kandel and I. L. Andrulis, Molecular and immunohistochemical identification of p53 alterations in bone and soft tissue sarcomas, Mod Pathol 9 (1996), 1-6.
    • (1996) Mod. Pathol. , vol.9 , pp. 1-6
    • Mousses, S.1    McAuley, L.2    Bell, R.S.3    Kandel, R.4    Andrulis, I.L.5
  • 132
    • 0031421683 scopus 로고    scopus 로고
    • Molecular alterations of the RB1 TP53 and MDM2 genes in primary and xenografted human osteosarcomas
    • A. Pellin, J. Boix-Ferrero, D. Carpio, D. Lopez-Terrada, C. Carda, S. Navarro et al. , Molecular alterations of the RB1, TP53, and MDM2 genes in primary and xenografted human osteosarcomas, Diagn Mol Pathol 6 (1997), 333-341.
    • (1997) Diagn. Mol. Pathol. , vol.6 , pp. 333-341
    • Pellin, A.1    Boix-Ferrero, J.2    Carpio, D.3    Lopez-Terrada, D.4    Carda, C.5    Navarro, S.6
  • 133
    • 4344708374 scopus 로고    scopus 로고
    • Selective usage of D-Type cyclins by Ewings tumors and rhabdomyosarcomas
    • J. Zhang, S. Hu, D. E. Schofield, P. H. Sorensen and T. J. Triche, Selective usage of D-Type cyclins by Ewing's tumors and rhabdomyosarcomas, Cancer Res 64 (2004), 6026-6034.
    • (2004) Cancer Res. , vol.64 , pp. 6026-6034
    • Zhang, J.1    Hu, S.2    Schofield, D.E.3    Sorensen, P.H.4    Triche, T.J.5
  • 134
    • 0027179611 scopus 로고
    • Reverse transcriptase pcr amplification of ews/fli-1 fusion transcripts as a diagnostic test for peripheral primitive neuroectodermal tumors of childhood
    • P. H. Sorensen, X. F. Liu, O. Delattre, J. M. Rowland, C. A. Biggs, G. Thomas et al. , Reverse transcriptase PCR amplification of EWS/FLI-1 fusion transcripts as a diagnostic test for peripheral primitive neuroectodermal tumors of childhood, Diagn Mol Pathol 2 (1993), 147-157.
    • (1993) Diagn. Mol. Pathol. , vol.2 , pp. 147-157
    • Sorensen, P.H.1    Liu, X.F.2    Delattre, O.3    Rowland, J.M.4    Biggs, C.A.5    Thomas, G.6
  • 135
  • 136
    • 0029618877 scopus 로고
    • A consensus polymerase chain reaction-oligonucleotide hybridization approach for the detection of chromosomal translocations in pediatric bone and soft tissue sarcomas
    • F. G. Barr, Q. B. Xiong and K. Kelly, A consensus polymerase chain reaction-oligonucleotide hybridization approach for the detection of chromosomal translocations in pediatric bone and soft tissue sarcomas, Am J Clin Pathol 104 (1995), 627-633.
    • (1995) Am. J. Clin. Pathol. , vol.104 , pp. 627-633
    • Barr, F.G.1    Xiong, Q.B.2    Kelly, K.3
  • 137
    • 0036328614 scopus 로고    scopus 로고
    • Practical application of molecular genetic testing as an aid to the surgical pathologic diagnosis of sarcomas: A rospective study
    • D. A. Hill, M. J. O'Sullivan, X. Zhu, R. T. Vollmer, P. A. Humphrey, L. P. Dehner et al. , Practical application of molecular genetic testing as an aid to the surgical pathologic diagnosis of sarcomas: a rospective study, Am J Surg Pathol 26 (2002), 965-977.
    • (2002) Am. J. Surg. Pathol. , vol.26 , pp. 965-977
    • Hill, D.A.1    O'sullivan, M.J.2    Zhu, X.3    Vollmer, R.T.4    Humphrey, P.A.5    Dehner, L.P.6
  • 138
    • 32844474047 scopus 로고    scopus 로고
    • Molecular diagnosis of Ewing sarcoma/primitive neuroectodermal tumor in routinely processed tissue: A comparison of two fish strategies and rt-pcr in malignant round cell tumors
    • R. S. Bridge, V. Rajaram, L. P. Dehner, J. D. Pfeifer and J. D. Perry, Molecular diagnosis of Ewing sarcoma/primitive neuroectodermal tumor in routinely processed tissue: a comparison of two FISH strategies and RT-PCR in malignant round cell tumors, Mod Pathol 19 (2006), 1-8.
    • (2006) Mod. Pathol. , vol.19 , pp. 1-8
    • Bridge, R.S.1    Rajaram, V.2    Dehner, L.P.3    Pfeifer, J.D.4    Perry, J.D.5
  • 139
    • 0028277974 scopus 로고
    • Interphase molecular cytogenetics of ewings sarcoma and peripheral neuroepithelioma t 11;22 with flanking and overlapping cosmid probes
    • C. Desmaze, J. Zucman, O. Delattre, T. Melot, G. Thomas and A. Aurias, Interphase molecular cytogenetics of Ewing's sarcoma and peripheral neuroepithelioma t(11;22) with flanking and overlapping cosmid probes, Cancer Genet Cytogenet 74 (1994), 13-18.
    • (1994) Cancer Genet. Cytogenet. , vol.74 , pp. 13-18
    • Desmaze, C.1    Zucman, J.2    Delattre, O.3    Melot, T.4    Thomas, G.5    Aurias, A.6
  • 140
    • 0032979365 scopus 로고    scopus 로고
    • Detection of ews-fli-1 fusion in ewing's sarcoma/peripheral primitive neuroectodermal tumor by fluorescence in situ hybridization using formalin-fixed paraffinembedded tissue
    • S. Kumar, S. Pack, D. Kumar, R. Walker, M. Quezado, Z. Zhuang et al. , Detection of EWS-FLI-1 fusion in Ewing's sarcoma/peripheral primitive neuroectodermal tumor by fluorescence in situ hybridization using formalin-fixed paraffinembedded tissue, Hum Pathol 30 (1999), 324-330.
    • (1999) Hum. Pathol. , vol.30 , pp. 324-330
    • Kumar, S.1    Pack, S.2    Kumar, D.3    Walker, R.4    Quezado, M.5    Zhuang, Z.6
  • 141
    • 0032979531 scopus 로고    scopus 로고
    • Documentation of ews gene rearrangements by fluorescence in-situ hybridization fish in frozen sections of ewings sarcoma-peripheral primitive neuroectodermal tumor
    • H. Monforte-Munoz, D. Lopez-Terrada, H. Affendie, J. M. Rowland and T. J. Triche, Documentation of EWS gene rearrangements by fluorescence in-situ hybridization (FISH) in frozen sections of Ewing's sarcoma-peripheral primitive neuroectodermal tumor, Am J Surg Pathol 23 (1999), 309-315.
    • (1999) Am. J. Surg. Pathol. , vol.23 , pp. 309-315
    • Monforte-Munoz, H.1    Lopez-Terrada, D.2    Affendie, H.3    Rowland, J.M.4    Triche, T.J.5
  • 142
    • 0029026614 scopus 로고
    • Sensitive detection of occult ewings cells by the reverse transcriptase-polymerase chain reaction
    • M. Peter, H. Magdelenat, J. Michon, T. Melot, O. Oberlin, J. M. Zucker et al. , Sensitive detection of occult Ewing's cells by the reverse transcriptase-polymerase chain reaction, Br J Cancer 72 (1995), 96-100.
    • (1995) Br. J. Cancer , vol.72 , pp. 96-100
    • Peter, M.1    Magdelenat, H.2    Michon, J.3    Melot, T.4    Oberlin, O.5    Zucker, J.M.6
  • 143
    • 0028913950 scopus 로고
    • Detection of 11;22 q24;q12 translocation-bearing cells in peripheral blood progenitor cells of patients with Ewings sarcoma family of tumors
    • J. A. Toretsky, L. Neckers and L. H. Wexler, Detection of (11;22)(q24;q12) translocation-bearing cells in peripheral blood progenitor cells of patients with Ewing's sarcoma family of tumors, J Natl Cancer Inst 87 (1995), 385-386.
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 385-386
    • Toretsky, J.A.1    Neckers, L.2    Wexler, L.H.3
  • 144
    • 0031756456 scopus 로고    scopus 로고
    • Ewing family tumors: Potential prognostic value of reverse-transcriptase polymerase chain reaction detection ofminimal residual disease in peripheral blood samples
    • E. de Alava, M. D. Lozano, A. Patino, L. Sierrasesumaga and F. J. Pardo-Mindan, Ewing family tumors: potential prognostic value of reverse-transcriptase polymerase chain reaction detection ofminimal residual disease in peripheral blood samples, Diagn Mol Pathol 7 (1998), 152-157.
    • (1998) Diagn. Mol. Pathol. , vol.7 , pp. 152-157
    • De Alava, E.1    Lozano, M.D.2    Patino, A.3    Sierrasesumaga, L.4    Pardo-Mindan, F.J.5
  • 146
    • 10744233322 scopus 로고    scopus 로고
    • The predictive potential of molecular detection in the nonmetastatic ewing family of tumors
    • S. Avigad, I. J. Cohen, J. Zilberstein, E. Liberzon, Y. Goshen, S. Ash et al. , The predictive potential of molecular detection in the nonmetastatic Ewing family of tumors, Cancer 100 (2004), 1053-1058.
    • (2004) Cancer , vol.100 , pp. 1053-1058
    • Avigad, S.1    Cohen, I.J.2    Zilberstein, J.3    Liberzon, E.4    Goshen, Y.5    Ash, S.6
  • 147
    • 0033119006 scopus 로고    scopus 로고
    • Differential transactivation by alternative ews-fli1 fusion proteins correlates with clinical heterogeneity in ewing's sarcoma
    • P. P. Lin, R. I. Brody, A. C. Hamelin, J. E. Bradner, J. H. Healey and M. Ladanyi, Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma, Cancer Res 59 (1999), 1428-1432.
    • (1999) Cancer Res. , vol.59 , pp. 1428-1432
    • Lin, P.P.1    Brody, R.I.2    Hamelin, A.C.3    Bradner, J.E.4    Healey, J.H.5    Ladanyi, M.6
  • 148
    • 0142074314 scopus 로고    scopus 로고
    • Oligonucleotides targeted against a junction oncogene are made efficient by nanotechnologies
    • A. Maksimenko, C. Malvy, G. Lambert, J. R. Bertrand, E. Fattal, J. Maccario et al. , Oligonucleotides targeted against a junction oncogene are made efficient by nanotechnologies, Pharm Res 20 (2003), 1565-1567.
    • (2003) Pharm. Res. , vol.20 , pp. 1565-1567
    • Maksimenko, A.1    Malvy, C.2    Lambert, G.3    Bertrand, J.R.4    Fattal, E.5    MacCario, J.6
  • 150
    • 20944448531 scopus 로고    scopus 로고
    • RNA-based nanoparticle treatment shows promise in ewing's sarcoma model
    • M. Hede, RNA-based nanoparticle treatment shows promise in Ewing's sarcoma model, J Natl Cancer Inst 97 (2005), 627.
    • (2005) J. Natl. Cancer Inst. , vol.97 , pp. 627
    • Hede, M.1
  • 151
    • 17644403503 scopus 로고    scopus 로고
    • A small interfering RNA targeting vascular endothelial growth factor inhibits ewings sarcoma growth in a xenograft mouse model
    • H. Guan, Z. Zhou, H. Wang, S. F. Jia,W. Liu and E. S. Kleinerman, A small interfering RNA targeting vascular endothelial growth factor inhibits Ewing's sarcoma growth in a xenograft mouse model, Clin Cancer Res 11 (2005), 2662-2669.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 2662-2669
    • Guan, H.1    Zhou, Z.2    Wang, S.F.3    Jiaw, L.H.4    Kleinerman, E.S.5
  • 152
    • 0034722888 scopus 로고    scopus 로고
    • The rapamycin-sensitive signal transduction pathway as a target for cancer therapy
    • M. Hidalgo and E. K. Rowinsky, The rapamycin-sensitive signal transduction pathway as a target for cancer therapy, Oncogene 19 (2000), 6680-6686.
    • (2000) Oncogene. , vol.19 , pp. 6680-6686
    • Hidalgo, M.1    Rowinsky, E.K.2
  • 153
    • 0344825088 scopus 로고    scopus 로고
    • Ewing's sarcoma: A miracle drug waiting to happen
    • R. Longtin, Ewing's sarcoma: a miracle drug waiting to happen? J Natl Cancer Inst 95 (2003), 1574-1576.
    • (2003) J. Natl. Cancer Inst. , vol.95 , pp. 1574-1576
    • Longtin, R.1
  • 154
    • 1642540093 scopus 로고    scopus 로고
    • Rapamycin induces the fusion-type independent downregulation of the ews/fli-1 proteins and inhibits ewings sarcoma cell proliferation
    • S. Mateo-Lozano, O. M. Tirado and V. Notario, Rapamycin induces the fusion-type independent downregulation of the EWS/FLI-1 proteins and inhibits Ewing's sarcoma cell proliferation, Oncogene 22 (2003), 9282-9287.
    • (2003) Oncogene. , vol.22 , pp. 9282-9287
    • Mateo-Lozano, S.1    Tirado, O.M.2    Notario, V.3
  • 156
    • 0028059816 scopus 로고
    • Genetic events in the development ofWilms tumor
    • M. J. Coppes, D. A. Haber and P. E. Grundy, Genetic events in the development ofWilms' tumor, N Engl JMed 331 (1994), 586-590.
    • (1994) N. Engl. J. Med. , vol.331 , pp. 586-590
    • Coppes, M.J.1    Haber, D.A.2    Grundy, P.E.3
  • 157
    • 34247579714 scopus 로고    scopus 로고
    • A tumor suppressor and oncogene: The WT1 story
    • L. Yang, Y. Han, F. Suarez Saiz and M. D. Minden, A tumor suppressor and oncogene: the WT1 story, Leukemia 21 (2007), 868-876.
    • (2007) Leukemia , vol.21 , pp. 868-876
    • Yang, L.1    Han, Y.2    Suarez Saiz, F.3    Minden, M.D.4
  • 159
    • 0025099787 scopus 로고
    • Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11Wilms tumor locus
    • K. M. Call, T. Glaser, C. Y. Ito, A. J. Buckler, J. Pelletier, D. A. Haber et al. , Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11Wilms' tumor locus, Cell 60 (1990), 509-520.
    • (1990) Cell , vol.60 , pp. 509-520
    • Call, K.M.1    Glaser, T.2    Ito, C.Y.3    Buckler, A.J.4    Pelletier, J.5    Haber, D.A.6
  • 160
    • 33751251698 scopus 로고    scopus 로고
    • Wilms tumor 1-associating protein regulates g2/m transition through stabilization of cyclin a2 mrna
    • U S A
    • K. Horiuchi, M. Umetani, T. Minami, H. Okayama, S. Takada, M. Yamamoto et al. , Wilms' tumor 1-associating protein regulates G2/M transition through stabilization of cyclin A2 mRNA, Proc Natl Acad Sci U S A 103 (2006), 17278-17283.
    • (2006) Proc. Natl. Acad. Sci. , vol.103 , pp. 17278-17283
    • Horiuchi, K.1    Umetani, M.2    Minami, T.3    Okayama, H.4    Takada, S.5    Yamamoto, M.6
  • 161
    • 0031686142 scopus 로고    scopus 로고
    • Microdissecting the genetic events in nephrogenic rests and Wilms tumor development
    • A. K. Charles, K. W. Brown and P. J. Berry, Microdissecting the genetic events in nephrogenic rests and Wilms' tumor development, Am J Pathol 153 (1998), 991-1000.
    • (1998) Am. J. Pathol. , vol.153 , pp. 991-1000
    • Charles, A.K.1    Brown, K.W.2    Berry, P.J.3
  • 162
    • 0027453021 scopus 로고
    • Homozygous somaticWt1 point mutations in sporadic unilateral Wilms tumor
    • U S A
    • M. J. Coppes, G. J. Liefers, P. Paul, H. Yeger and B. R. Williams, Homozygous somaticWt1 point mutations in sporadic unilateral Wilms tumor, Proc Natl Acad Sci U S A 90 (1993), 1416-1419.
    • (1993) Proc. Natl. Acad. Sci. , vol.90 , pp. 1416-1419
    • Coppes, M.J.1    Liefers, G.J.2    Paul, P.3    Yeger, H.4    Williams, B.R.5
  • 163
    • 0024505754 scopus 로고
    • Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms tumor cells
    • A. E. Reeve, S. A. Sih, A. M. Raizis and A. P. Feinberg, Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms' tumor cells, Mol Cell Biol 9 (1989), 1799-1803.
    • (1989) Mol. Cell Biol. , vol.9 , pp. 1799-1803
    • Reeve, A.E.1    Sih, S.A.2    Raizis, A.M.3    Feinberg, A.P.4
  • 164
    • 0034024407 scopus 로고    scopus 로고
    • Genetics of Beckwith-Wiedemann syndrome-associated tumors: Common genetic pathways
    • M. Steenman, A. Westerveld and A. Mannens, Genetics of Beckwith-Wiedemann syndrome-associated tumors: common genetic pathways, Genes Chromosomes Cancer 28 (2000), 1-13.
    • (2000) Genes Chromosomes Cancer , vol.28 , pp. 1-13
    • Steenman, M.1    Westerveld, A.2    Mannens, A.3
  • 165
    • 0033975096 scopus 로고    scopus 로고
    • Beckwith-Wiedemann syndrome: Imprinting in clusters revisited
    • E. R. Maher and W. Reik, Beckwith-Wiedemann syndrome: imprinting in clusters revisited, J Clin Invest 105 (2000), 247-252.
    • (2000) J. Clin. Invest. , vol.105 , pp. 247-252
    • Maher, E.R.1    Reik, W.2
  • 166
    • 33846846526 scopus 로고    scopus 로고
    • An X chromosome gene WTX, is commonly inactivated in Wilms tumor
    • M. N. Rivera, W. J. Kim, J. Wells, D. R. Driscoll, B. W. Brannigan, M. Han et al. , An X chromosome gene, WTX, is commonly inactivated in Wilms tumor, Science 315 (2007), 642-645.
    • (2007) Science , vol.315 , pp. 642-645
    • Rivera, M.N.1    Kim, W.J.2    Wells, J.3    Driscoll, D.R.4    Brannigan, B.W.5    Han, M.6
  • 167
    • 34249061491 scopus 로고    scopus 로고
    • Wilms tumor suppressor wtx negatively regulates wnt/beta-catenin signaling
    • M. B. Major, N. D. Camp, J. D. Berndt, X. Yi, S. J. Goldenberg, C. Hubbert et al. , Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling, Science 316 (2007), 1043-1046.
    • (2007) Science , vol.316 , pp. 1043-1046
    • Major, M.B.1    Camp, N.D.2    Berndt, J.D.3    Yi, X.4    Goldenberg, S.J.5    Hubbert, C.6
  • 168
    • 31444451325 scopus 로고    scopus 로고
    • Loss of heterozygosity for chromosomes 1p and 16q is an adverse prognostic factor in favorablehistology Wilms tumor: A report from the national wilms tumor study group
    • P. E. Grundy, N. E. Breslow, S. Li, E. Perlman, J. B. Beckwith, M. L. Ritchey et al. , Loss of heterozygosity for chromosomes 1p and 16q is an adverse prognostic factor in favorablehistology Wilms tumor: a report from the National Wilms Tumor Study Group, J Clin Oncol 23 (2005), 7312-7321.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 7312-7321
    • Grundy, P.E.1    Breslow, N.E.2    Li, S.3    Perlman, E.4    Beckwith, J.B.5    Ritchey, M.L.6
  • 169
    • 0031299355 scopus 로고    scopus 로고
    • Molecular basis of Wilms tumor
    • P. Grundy, Molecular basis of Wilms' tumor, Cancer Treat Res 92 (1997), 101-123.
    • (1997) Cancer Treat. Res. , vol.92 , pp. 101-123
    • Grundy, P.1
  • 170
    • 0035061543 scopus 로고    scopus 로고
    • Refinement within single yeast artificial chromosome clones of a minimal region commonly deleted on the short arm of chromosome 7 in Wilms tumours
    • D. Perotti, M. A. Testi, P. Mondini, S. Pilotti, E. D. Green, A. Pession et al. , Refinement within single yeast artificial chromosome clones of a minimal region commonly deleted on the short arm of chromosome 7 in Wilms tumours, Genes Chromosomes Cancer 31 (2001), 42-47.
    • (2001) Genes. Chromosomes Cancer , vol.31 , pp. 42-47
    • Perotti, D.1    Testi, M.A.2    Mondini, P.3    Pilotti, S.4    Green, E.D.5    Pession, A.6
  • 172
    • 0033677022 scopus 로고    scopus 로고
    • Frequent association of beta-catenin and WT1 mutations in Wilms tumors
    • S. Maiti, R. Alam, C. I. Amos and V. Huff, Frequent association of beta-catenin and WT1 mutations in Wilms tumors, Cancer Res 60 (2000), 6288-6292.
    • (2000) Cancer Res. , vol.60 , pp. 6288-6292
    • Maiti, S.1    Alam, R.2    Amos, C.I.3    Huff, V.4
  • 173
  • 174
    • 0033198499 scopus 로고    scopus 로고
    • High telomerase reverse transcriptase htertmessenger rna level correlates with tumor recurrence in patients with favorable histology Wilms tumor
    • J. S. Dome, S. Chung, T. Bergemann, C. B. Umbricht, M. Saji, L. A. Carey et al. , High telomerase reverse transcriptase (hTERT)messenger RNA level correlates with tumor recurrence in patients with favorable histology Wilms' tumor, Cancer Res 59 (1999), 4301-4307.
    • (1999) Cancer Res. , vol.59 , pp. 4301-4307
    • Dome, J.S.1    Chung, S.2    Bergemann, T.3    Umbricht, C.B.4    Saji, M.5    Carey, L.A.6
  • 175
    • 0035253655 scopus 로고    scopus 로고
    • Expression of the neurotrophin receptor trkb is associated with unfavorable outcome in wilms tumor
    • A. Eggert, M. A. Grotzer, N. Ikegaki, H. Zhao, A. Cnaan, G. M. Brodeur et al. , Expression of the neurotrophin receptor TrkB is associated with unfavorable outcome in Wilms' tumor, J Clin Oncol 19 (2001), 689-696.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 689-696
    • Eggert, A.1    Grotzer, M.A.2    Ikegaki, N.3    Zhao, H.4    Cnaan, A.5    Brodeur, G.M.6
  • 178
    • 36749050382 scopus 로고    scopus 로고
    • Defective chromosome segregation and telomere dysfunction in aggressive wilms tumors
    • Y. Stewenius, Y. Jin, I. Ora, J. de Kraker, J. Bras, A. Frigyesi et al. , Defective chromosome segregation and telomere dysfunction in aggressive Wilms' tumors, Clin Cancer Res 13 (2007), 6593-6602.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 6593-6602
    • Stewenius, Y.1    Jin, Y.2    Ora, I.3    De Kraker, J.4    Bras, J.5    Frigyesi, A.6
  • 180
    • 0031736957 scopus 로고    scopus 로고
    • Confirmation of FWT1 as a wilms' tumour susceptibility gene and phenotypic characteristics of wilms' tumour attributable to fwt1
    • N. Rahman, F. Abidi, D. Ford, L. Arbour, E. Rapley, P. Tonin et al. , Confirmation of FWT1 as a Wilms' tumour susceptibility gene and phenotypic characteristics of Wilms' tumour attributable to FWT1, Hum Genet 103 (1998), 547-556.
    • (1998) Hum. Genet. , vol.103 , pp. 547-556
    • Rahman, N.1    Abidi, F.2    Ford, D.3    Arbour, L.4    Rapley, E.5    Tonin, P.6
  • 181
    • 0032053822 scopus 로고    scopus 로고
    • Linkage of familial Wilms tumor predisposition to chromosome 19 and a two-locus model for the etiology of familial tumors
    • J. M. McDonald, E. C. Douglass, R. Fisher, C. F. Geiser, C. E. Krill, L. C. Strong et al. , Linkage of familial Wilms' tumor predisposition to chromosome 19 and a two-locus model for the etiology of familial tumors, Cancer Res 58 (1998), 1387-1390.
    • (1998) Cancer Res. , vol.58 , pp. 1387-1390
    • McDonald, J.M.1    Douglass, E.C.2    Fisher, R.3    Geiser, C.F.4    Krill, C.E.5    Strong, L.C.6
  • 182
    • 0029765587 scopus 로고    scopus 로고
    • Identification of novel regions of deletion in familial Wilms' tumor by comparative genomic hybridization
    • R. A. Altura, M. Valentine, H. Li, J. M. Boyett, P. Shearer, P. Grundy et al. , Identification of novel regions of deletion in familial Wilms' tumor by comparative genomic hybridization, Cancer Res 56 (1996), 3837-3841.
    • (1996) Cancer Res. , vol.56 , pp. 3837-3841
    • Altura, R.A.1    Valentine, M.2    Li, H.3    Boyett, J.M.4    Shearer, P.5    Grundy, P.6
  • 183
    • 33749266701 scopus 로고    scopus 로고
    • Syndromes and constitutional chromosomal abnormalities associated withWilms tumour
    • R. H. Scott, C. A. Stiller, L. Walker and N. Rahman, Syndromes and constitutional chromosomal abnormalities associated withWilms tumour, JMedGenet 43 (2006), 705-715.
    • (2006) J. Med. Genet. , vol.43 , pp. 705-715
    • Scott, R.H.1    Stiller, C.A.2    Walker, L.3    Rahman, N.4
  • 184
    • 0018668497 scopus 로고
    • Aniridia-Wilms tumor association: Evidence for specific deletion of 11p13
    • U. Francke, L. B. Holmes, L. Atkins and V. M. Riccardi, Aniridia-Wilms' tumor association: evidence for specific deletion of 11p13, Cytogenet Cell Genet 24 (1979), 185-192.
    • (1979) Cytogenet. Cell Genet. , vol.24 , pp. 185-192
    • Francke, U.1    Holmes, L.B.2    Atkins, L.3    Riccardi, V.M.4
  • 185
    • 0026907525 scopus 로고
    • Constitutional mutations in the wt1 gene in patients with denys-drash syndrome
    • P. N. Baird, A. Santos, N. Groves, L. Jadresic and J. K. Cowell, Constitutional mutations in the WT1 gene in patients with Denys-Drash syndrome, Hum Mol Genet 1 (1992), 301-305.
    • (1992) Hum. Mol. Genet. , vol.1 , pp. 301-305
    • Baird, P.N.1    Santos, A.2    Groves, N.3    Jadresic, L.4    Cowell, J.K.5
  • 187
    • 0027175810 scopus 로고
    • Evidence that wt1 mutations in denys-drash syndrome patients may act in a dominantnegative fashion
    • M. H. Little, K. A. Williamson, M. Mannens, A. Kelsey, C. Gosden, N. D. Hastie et al. , Evidence that WT1 mutations in Denys-Drash syndrome patients may act in a dominantnegative fashion, Hum Mol Genet 2 (1993), 259-264.
    • (1993) Hum. Mol. Genet. , vol.2 , pp. 259-264
    • Little, M.H.1    Williamson, K.A.2    Mannens, M.3    Kelsey, A.4    Gosden, C.5    Hastie, N.D.6
  • 188
    • 17444381939 scopus 로고    scopus 로고
    • Translocation carcinomas of the kidney
    • P. Argani and P. Ladanyi, Translocation carcinomas of the kidney, Clin Lab Med 25 (2005), 363-378.
    • (2005) Clin. Lab. Med. , vol.25 , pp. 363-378
    • Argani, P.1    Ladanyi, P.2
  • 189
    • 0010346928 scopus 로고    scopus 로고
    • Primary renal neoplasms with the aspl-tfe3 gene fusion of alveolar soft part sarcoma: A distinctive tumor entity previously included among renal cell carcinomas of children and adolescents
    • P. Argani, C. R. Antonescu, P. B. Illei, M. Y. Lui, C. F. Timmons, R. Newbury et al. , Primary renal neoplasms with the ASPL-TFE3 gene fusion of alveolar soft part sarcoma: a distinctive tumor entity previously included among renal cell carcinomas of children and adolescents, Am J Pathol 159 (2001), 179-192.
    • (2001) Am. J. Pathol. , vol.159 , pp. 179-192
    • Argani, P.1    Antonescu, C.R.2    Illei, P.B.3    Lui, M.Y.4    Timmons, C.F.5    Newbury, R.6
  • 190
    • 0037230146 scopus 로고    scopus 로고
    • Renal cell carcinoma with t X;17: Singular pediatric neoplasm with specific phenotype/ genotype features
    • E. Zambrano and M. Reyes-Mugica, Renal cell carcinoma with t(X;17): singular pediatric neoplasm with specific phenotype/ genotype features, Pediatr Dev Pathol 6 (2003), 84-87.
    • (2003) Pediatr. Dev. Pathol. , vol.6 , pp. 84-87
    • Zambrano, E.1    Reyes-Mugica, M.2
  • 191
    • 0037716678 scopus 로고    scopus 로고
    • Five new cases of juvenile renal cell carcinoma with translocations involving Xp11. 2: A cytogenetic andmorphologic study
    • C. Perot, L. Boccon-Gibod, R. Bouvier, F. Doz, J. C. Fournet, P. Freneaux et al. , Five new cases of juvenile renal cell carcinoma with translocations involving Xp11. 2: a cytogenetic andmorphologic study, Cancer Genet Cytogenet 143 (2003), 93-99.
    • (2003) Cancer Genet. Cytogenet. , vol.143 , pp. 93-99
    • Perot, C.1    Boccon-Gibod, L.2    Bouvier, R.3    Doz, F.4    Fournet, J.C.5    Freneaux, P.6
  • 192
    • 3442875929 scopus 로고    scopus 로고
    • Morphologic and molecular characterization of renal cell carcinoma in children and young adults
    • E. Bruder, O. Passera, D. Harms, I. Leuschner, M. Ladanyi, P. Argani et al. , Morphologic and molecular characterization of renal cell carcinoma in children and young adults, Am J Surg Pathol 28 (2004), 1117-1132.
    • (2004) Am. J. Surg. Pathol. , vol.28 , pp. 1117-1132
    • Bruder, E.1    Passera, O.2    Harms, D.3    Leuschner, I.4    Ladanyi, M.5    Argani, P.6
  • 193
    • 10144257193 scopus 로고    scopus 로고
    • The t x;1 p11. 2;q21. 2 translocation in papillary renal cell carcinoma fuses a novel gene prcc to the tfe3 transcription factor gene
    • S. K. Sidhar, J. Clark, S. Gill, S. Hamoudi, A. J. Crew, R. Gwilliam et al. , The t(X;1)(p11. 2;q21. 2) translocation in papillary renal cell carcinoma fuses a novel gene PRCC to the TFE3 transcription factor gene, Hum Mol Genet 5 (1996), 1333-1338.
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 1333-1338
    • Sidhar, S.K.1    Clark, J.2    Gill, S.3    Hamoudi, S.4    Crew, A.J.5    Gwilliam, R.6
  • 194
    • 0030463172 scopus 로고    scopus 로고
    • Fusion of the transcription factor tfe3 gene to a novel gene prcc in t x;1 p11;q21-positive papillary renal cell carcinomas
    • U S A
    • M. A. Weterman, M. Wilbrink and A. Geurts van Kessel, Fusion of the transcription factor TFE3 gene to a novel gene, PRCC, in t(X;1)(p11;q21)- positive papillary renal cell carcinomas, Proc Natl Acad Sci U S A 93 (1996), 15294-15298.
    • (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 15294-15298
    • Weterman, M.A.1    Wilbrink, M.2    Kessel Van A.Geurts3
  • 195
    • 0034975421 scopus 로고    scopus 로고
    • A distinctive pediatric renal neoplasm characterized by epithelioid morphology basement membrane production focal hmb45 immunoreactivity and t 6;11 p21. 1;q12 chromosome translocation
    • P. Argani, A. Hawkins, C. A. Griffin, J. D. Goldstein, M. Haas, J. B. Beckwith et al. , A distinctive pediatric renal neoplasm characterized by epithelioid morphology, basement membrane production, focal HMB45 immunoreactivity, and t(6;11)(p21. 1;q12) chromosome translocation, Am J Pathol 158 (2001), 2089-2096.
    • (2001) Am. J. Pathol. , vol.158 , pp. 2089-2096
    • Argani, P.1    Hawkins, A.2    Griffin, C.A.3    Goldstein, J.D.4    Haas, M.5    Beckwith, J.B.6
  • 196
    • 19944433827 scopus 로고    scopus 로고
    • Renal carcinomas with the t 6;11 p21;q12: Clinicopathologic features and demonstration of the specific alpha-tfeb gene fusion by immunohistochemistry rt-pcr and dna pcr
    • P. Argani, M. Lae, B. Hutchinson, V. E. Reuter, M. H. Collins, J. Perentesis et al. , Renal carcinomas with the t(6;11)(p21;q12): clinicopathologic features and demonstration of the specific alpha-TFEB gene fusion by immunohistochemistry, RT-PCR, and DNA PCR, Am J Surg Pathol 29 (2005), 230-240.
    • (2005) Am. J. Surg. Pathol. , vol.29 , pp. 230-240
    • Argani, P.1    Lae, M.2    Hutchinson, B.3    Reuter, V.E.4    Collins, M.H.5    Perentesis, J.6
  • 197
    • 33645985526 scopus 로고    scopus 로고
    • Expression of etv6- ntrk in classical, cellular andmixed subtypes of congenital mesoblastic nephroma
    • J. Anderson, S. Gibson andN. J. Sebire, Expression of ETV6- NTRK in classical, cellular andmixed subtypes of congenital mesoblastic nephroma, Histopathology 48 (2006), 748-753.
    • (2006) Histopathology , vol.48 , pp. 748-753
    • Anderson, J.1    Gibson, S.2    Sebire, N.J.3
  • 198
    • 0032533497 scopus 로고    scopus 로고
    • ETV6-ntrk3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma
    • S. R. Knezevich, M. J. Garnett, T. J. Pysher, J. B. Beckwith, P. E. Grundy and P. H. Sorensen, ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma, Cancer Res 58 (1998), 5046-5048.
    • (1998) Cancer Res. , vol.58 , pp. 5046-5048
    • Knezevich, S.R.1    Garnett, M.J.2    Pysher, T.J.3    Beckwith, J.B.4    Grundy, P.E.5    Sorensen, P.H.6
  • 200
    • 0031680298 scopus 로고    scopus 로고
    • Atypical teratoid/rhabdoid tumor of the central nervous system: A highly malignant tumor of infancyand childhood requently mistaken for medulloblastoma: A pediatriconcology group study
    • P. C. Burger, I. T. Yu, T. Tihan, H. S. Friedman, D. R. Strother, J. L. Kepner et al. , Atypical teratoid/rhabdoid tumor of the central nervous system: a highly malignant tumor of infancyand childhood requently mistaken for medulloblastoma: a PediatricOncology Group study, AmJ Surg Pathol 22 (1998), 1083-1092.
    • (1998) Am. J. Surg. Pathol. , vol.22 , pp. 1083-1092
    • Burger, P.C.1    Yu, I.T.2    Tihan, T.3    Friedman, H.S.4    Strother, D.R.5    Kepner, J.L.6
  • 203
    • 0027526407 scopus 로고
    • In situ numeric analysis of centromeric regions of chromosomes 1 12 and 15 of seminomas, nonseminomatous germ cell tumors and carcinoma in situ of human testis
    • L. H. Looijenga, A. J. Gillis, W. L. Van Putten and J. W. Oosterhuis, In situ numeric analysis of centromeric regions of chromosomes 1, 12, and 15 of seminomas, nonseminomatous germ cell tumors, and carcinoma in situ of human testis, Lab Invest 68 (1993), 211-219.
    • (1993) Lab. Invest. , vol.68 , pp. 211-219
    • Looijenga, L.H.1    Gillis, A.J.2    Van Putten, W.L.3    Oosterhuis, J.W.4
  • 204
    • 10544251842 scopus 로고    scopus 로고
    • Detection of chromosomal DNA gains and losses in testicular germ cell tumors by comparative genomic hybridization
    • W. M. Korn, D. E. Oide Weghuis, R. F. Suijkerbuijk, U. Schmidt, T. Otto, S. du Manoir et al. , Detection of chromosomal DNA gains and losses in testicular germ cell tumors by comparative genomic hybridization, Genes Chromosomes Cancer 17 (1996), 78-87.
    • (1996) Genes Chromosomes Cancer , vol.17 , pp. 78-87
    • Korn, W.M.1    Oide Weghuis, D.E.2    Suijkerbuijk, R.F.3    Schmidt, U.4    Otto, T.5    Du Manoir, S.6
  • 205
    • 0028046406 scopus 로고
    • Loss of heterozygosity identifies multiple sites of allelic deletions on chromosome 1 in human male germ cell tumors
    • S. Mathew, V. V. Murty, G. J. Bosl and R. S. Chaganti, Loss of heterozygosity identifies multiple sites of allelic deletions on chromosome 1 in human male germ cell tumors, Cancer Res 54 (1994), 6265-6269.
    • (1994) Cancer Res. , vol.54 , pp. 6265-6269
    • Mathew, S.1    Murty, V.V.2    Bosl, G.J.3    Chaganti, R.S.4
  • 207
    • 0028210523 scopus 로고
    • Differential expression of protooncogenes in human germ cell tumors of the testis
    • T. Shuin, H. Misaki, Y. Kubota, M. Yao and M. Hosaka, Differential expression of protooncogenes in human germ cell tumors of the testis, Cancer 73 (1994), 1721-1727.
    • (1994) Cancer , vol.73 , pp. 1721-1727
    • Shuin, T.1    Misaki, H.2    Kubota, Y.3    Yao, M.4    Hosaka, M.5
  • 209
    • 0027944119 scopus 로고
    • Frequent allelic deletions and loss of expression characterize the dcc gene in male germ cell tumors
    • V. V. Murty, R. G. Li, J. Houldsworth, D. L. Bronson, V. E. Reuter, G. J. Bosl et al. , Frequent allelic deletions and loss of expression characterize the DCC gene in male germ cell tumors, Oncogene 9 (1994), 3227-3231.
    • (1994) Oncogene , vol.9 , pp. 3227-3231
    • Murty, V.V.1    Li, R.G.2    Houldsworth, J.3    Bronson, D.L.4    Reuter, V.E.5    Bosl, G.J.6
  • 211
    • 0025092775 scopus 로고
    • Genetics and biology of human ovarian teratomas i cytogenetic analysis and mechanism of origin
    • U. Surti, L. Hoffner, A. Chakravarti and R. E. Ferrell, Genetics and biology of human ovarian teratomas. I. Cytogenetic analysis and mechanism of origin, Am J Hum Genet 47 (1990), 635-643.
    • (1990) Am. J. Hum. Genet. , vol.47 , pp. 635-643
    • Surti, U.1    Hoffner, L.2    Chakravarti, A.3    Ferrell, R.E.4
  • 212
    • 0032527910 scopus 로고    scopus 로고
    • Genetic analysis of ovarian germ cell tumors by comparative genomic hybridization
    • M. A. Riopel, A. Spellerberg, C. A. Griffin and E. J. Perlman, Genetic analysis of ovarian germ cell tumors by comparative genomic hybridization, Cancer Res 58 (1998), 3105-3110.
    • (1998) Cancer Res. , vol.58 , pp. 3105-3110
    • Riopel, M.A.1    Spellerberg, A.2    Griffin, C.A.3    Perlman, E.J.4
  • 214
    • 0025181655 scopus 로고
    • Cytogenetic and immunohistochemical evidence for the germcell origin of a subset of acute leukemias associated with mediastinal germ cell tumors
    • M. Ladanyi, F. Samaniego, V. E. Reuter, R. J. Motzer, S. C. Jhanwar, G. J. Bosl et al. , Cytogenetic and immunohistochemical evidence for the germcell origin of a subset of acute leukemias associated with mediastinal germ cell tumors, J Natl Cancer Inst 82 (1990), 221-227.
    • (1990) J. Natl. Cancer Inst. , vol.82 , pp. 221-227
    • Ladanyi, M.1    Samaniego, F.2    Reuter, V.E.3    Motzer, R.J.4    Jhanwar, S.C.5    Bosl, G.J.6
  • 215
    • 0028961918 scopus 로고
    • Numerical sex chromosomal abnormalities in pineal teratomas by cytogenetic analysis and fluorescence in situ hybridization
    • I. T. Yu, C. A. Griffin, P. C. Phillips, L. C. Strauss and E. J. Perlman, Numerical sex chromosomal abnormalities in pineal teratomas by cytogenetic analysis and fluorescence in situ hybridization, Lab Invest 72 (1995), 419-423.
    • (1995) Lab Invest , vol.72 , pp. 419-423
    • Yu, I.T.1    Griffin, C.A.2    Phillips, P.C.3    Strauss, L.C.4    Perlman, E.J.5
  • 216
    • 0032961983 scopus 로고    scopus 로고
    • Chromosome abnormalities of eighty-one pediatric germ cell tumors: Sex- age- site- and histopathology-related differences - A childrens cancer group study
    • K. J. Bussey, H. J. Lawce, S. B. Olson, D. C. Arthur, D. K. Kalousek, M. Krailo et al. , Chromosome abnormalities of eighty-one pediatric germ cell tumors: sex-, age-, site-, and histopathology-related differences - a Children's Cancer Group study, Genes Chromosomes Cancer 25 (1999), 134-146.
    • (1999) Genes Chromosomes Cancer , vol.25 , pp. 134-146
    • Bussey, K.J.1    Lawce, H.J.2    Olson, S.B.3    Arthur, D.C.4    Kalousek, D.K.5    Krailo, M.6
  • 217
    • 0028142538 scopus 로고
    • Cytogenetic analysis of childhood endodermal sinus tumors: A pediatric oncology group study
    • E. J. Perlman, B. Cushing, E. Hawkins and C. A. Griffin, Cytogenetic analysis of childhood endodermal sinus tumors: a Pediatric Oncology Group study, Pediatr Pathol 14 (1994), 695-708.
    • (1994) Pediatr. Pathol. , vol.14 , pp. 695-708
    • Perlman, E.J.1    Cushing, B.2    Hawkins, E.3    Griffin, C.A.4
  • 219
    • 0020634258 scopus 로고
    • The distribution of chromosomal genotypes associated with Turner's syndrome: Livebirth prevalence rates and evidence for diminished fetal mortality and severity in genotypes associated with structural X abnormalities or mosaicism
    • E. B. Hook and D. Warburton, The distribution of chromosomal genotypes associated with Turner's syndrome: livebirth prevalence rates and evidence for diminished fetal mortality and severity in genotypes associated with structural X abnormalities or mosaicism, Hum Genet 64 (1983), 24-27.
    • (1983) Hum. Genet. , vol.64 , pp. 24-27
    • Hook, E.B.1    Warburton, D.2
  • 220
    • 0033365196 scopus 로고    scopus 로고
    • Gonadoblastoma, testicular and prostate cancers and the tspy gene
    • Y. F. Lau, Gonadoblastoma, testicular and prostate cancers, and the TSPY gene, Am J Hum Genet 64 (1999), 921-927.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 921-927
    • Lau, Y.F.1
  • 222
    • 25844442348 scopus 로고    scopus 로고
    • IGF2/h19 imprinting analysis of human germ cell tumors gcts using the methylationsensitive single-nucleotide primer extension method reflects the origin of gcts in different stages of primordial germ cell development
    • S. Sievers, K. Alemazkour, S. Zahn, E. J. Perlman, A. J. Gillis, L. H. Looijenga et al. , IGF2/H19 imprinting analysis of human germ cell tumors (GCTs) using the methylationsensitive single-nucleotide primer extension method reflects the origin of GCTs in different stages of primordial germ cell development, Genes Chromosomes Cancer 44 (2005), 256-264.
    • (2005) Genes. Chromosomes Cancer , vol.44 , pp. 256-264
    • Sievers, S.1    Alemazkour, K.2    Zahn, S.3    Perlman, E.J.4    Gillis, A.J.5    Looijenga, L.H.6
  • 223
    • 67449089704 scopus 로고    scopus 로고
    • Yolk sac tumor but not seminoma or teratoma is associated with abnormal epigenetic reprogramming pathway and shows frequent hypermethylation of various tumor suppressor genes
    • S. Furukawa, M. Haruta, Y. Arai, S. Honda, J. Ohshima, W. Sugawara et al. , Yolk sac tumor but not seminoma or teratoma is associated with abnormal epigenetic reprogramming pathway and shows frequent hypermethylation of various tumor suppressor genes, Cancer Sci 100 (2009), 698-708.
    • (2009) Cancer Sci. , vol.100 , pp. 698-708
    • Furukawa, S.1    Haruta, M.2    Arai, Y.3    Honda, S.4    Ohshima, J.5    Sugawara, W.6
  • 224
    • 0023767249 scopus 로고
    • Identification of germline and somatic mutations affecting the retinoblastoma gene
    • J. M. Dunn, R. A. Phillips, A. J. Becker and B. L. Gallie, Identification of germline and somatic mutations affecting the retinoblastoma gene, Science 241 (1988), 1797-1800.
    • (1988) Science , vol.241 , pp. 1797-1800
    • Dunn, J.M.1    Phillips, R.A.2    Becker, A.J.3    Gallie, B.L.4
  • 225
    • 0015043748 scopus 로고
    • Mutation and cancer: Statistical study of retinoblastoma
    • U S A
    • A. G. Jr. Knudson, Mutation and cancer: statistical study of retinoblastoma, Proc Natl Acad Sci U S A 68 (1971), 820-823.
    • (1971) Proc. Natl. Acad. Sci. , vol.68 , pp. 820-823
    • Knudson Jr., A.G.1
  • 226
    • 3342996653 scopus 로고    scopus 로고
    • Retinoblastoma: Revisiting the model prototype of inherited cancer
    • D. R. Lohmann and B. L. Gallie, Retinoblastoma: revisiting the model prototype of inherited cancer, Am J Med Genet C Semin Med Genet 129C (2004), 23-28.
    • (2004) Am. J. Med. Genet. C Semin Med. Genet. , vol.C , pp. 23-28
    • Lohmann, D.R.1    Gallie, B.L.2
  • 228
    • 0024382804 scopus 로고
    • Preferential germline mutation of the paternal allele in retinoblastoma
    • X. P. Zhu, J. M. Dunn, R. A. Phillips, A. D. Goddard, K. E. Paton, A. Becker et al. , Preferential germline mutation of the paternal allele in retinoblastoma, Nature 340 (1989), 312-313.
    • (1989) Nature , vol.340 , pp. 312-313
    • Zhu, X.P.1    Dunn, J.M.2    Phillips, R.A.3    Goddard, A.D.4    Paton, K.E.5    Becker, A.6
  • 229
    • 0033786378 scopus 로고    scopus 로고
    • Rb function in cell-cycle regulation and apoptosis
    • J. W. Harbour and D. C. Dean, Rb function in cell-cycle regulation and apoptosis, Nat Cell Biol 2 (2000), E65-67.
    • (2000) Nat. Cell Biol. , vol.2
    • Harbour, J.W.1    Dean, D.C.2
  • 231
    • 33748870748 scopus 로고    scopus 로고
    • Hereditary cancer predisposition in children: Genetic basis and clinical implications
    • B. Strahm and D. Malkin, Hereditary cancer predisposition in children: genetic basis and clinical implications, Int J Cancer 119 (2006), 2001-2006.
    • (2006) Int. J. Cancer , vol.119 , pp. 2001-2006
    • Strahm, B.1    Malkin, D.2
  • 233
    • 0023106062 scopus 로고
    • Human retinoblastoma susceptibility gene: Cloning Identification and sequence
    • W. H. Lee, R. Bookstein, F. Hong, L. J. Young, J. Y. Shew and E. Y. Lee, Human retinoblastoma susceptibility gene: cloning, identification, and sequence, Science 235 (1987), 1394-1399.
    • (1987) Science , vol.235 , pp. 1394-1399
    • Lee, W.H.1    Bookstein, R.2    Hong, F.3    Young, L.J.4    Shew, J.Y.5    Lee, E.Y.6
  • 234
    • 0036884829 scopus 로고    scopus 로고
    • The retinoblastoma tumour suppressor in development and cancer
    • M. Classon and E. Harlow, The retinoblastoma tumour suppressor in development and cancer, Nat Rev Cancer 2 (2002), 910-917.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 910-917
    • Classon, M.1    Harlow, E.2
  • 235
    • 0031737407 scopus 로고    scopus 로고
    • Overview of RB gene mutations in patients with retinoblastoma implications for clinical genetic screening
    • J. W. Harbour, Overview of RB gene mutations in patients with retinoblastoma. Implications for clinical genetic screening, Ophthalmology 105 (1998), 1442-1447.
    • (1998) Ophthalmology , vol.105 , pp. 1442-1447
    • Harbour, J.W.1
  • 237
    • 66149083996 scopus 로고    scopus 로고
    • High incidence of allelic loss at 16q12. 2 region spanning rbl2/p130 gene in retinoblastoma
    • K. Priya, S. R. Jada, B. L. Quah, T. C. Quah and P. S. Lai, High incidence of allelic loss at 16q12. 2 region spanning RBL2/p130 gene in retinoblastoma, Cancer Biol Ther 8 (2009), 714-717.
    • (2009) Cancer Biol. Ther. , vol.8 , pp. 714-717
    • Priya, K.1    Jada, S.R.2    Quah, B.L.3    Quah, T.C.4    Lai, P.S.5
  • 238
    • 34547457538 scopus 로고    scopus 로고
    • Identification of genes associated with tumorigenesis of retinoblastoma by microarray analysis
    • S. Chakraborty, S. Khare, S. K. Dorairaj, V. C. Prabhakaran, D. R. Prakash and D. R. Kumar, Identification of genes associated with tumorigenesis of retinoblastoma by microarray analysis, Genomics 90 (2007), 344-353.
    • (2007) Genomics , vol.90 , pp. 344-353
    • Chakraborty, S.1    Khare, S.2    Dorairaj, S.K.3    Prabhakaran, V.C.4    Prakash, D.R.5    Kumar, D.R.6
  • 240
    • 0042824128 scopus 로고    scopus 로고
    • Epidemiology of primary hepatic malignancies in U. S. children
    • A. Darbari, K. M. Sabin, C. N. Shapiro and K. B. Schwarz, Epidemiology of primary hepatic malignancies in U. S. children, Hepatology 38 (2003), 560-566.
    • (2003) Hepatology , vol.38 , pp. 560-566
    • Darbari, A.1    Sabin, K.M.2    Shapiro, C.N.3    Schwarz, K.B.4
  • 241
    • 0008878205 scopus 로고
    • Primary hepatic tumors of childhood
    • A. G. Weinberg and M. J. Finegold, Primary hepatic tumors of childhood, Hum Pathol 14 (1983), 512-537.
    • (1983) Hum. Pathol. , vol.14 , pp. 512-537
    • Weinberg, A.G.1    Finegold, M.J.2
  • 242
    • 0027270242 scopus 로고
    • Liver tumors in childhood: Epidemiology and clinics
    • F. F. Bellani and M. Massimino, Liver tumors in childhood: epidemiology and clinics, J Surg Oncol Suppl 3 (1993), 119-121.
    • (1993) J. Surg. Oncol. Suppl. , vol.3 , pp. 119-121
    • Bellani, F.F.1    Massimino, M.2
  • 243
    • 71049119486 scopus 로고    scopus 로고
    • Predictive power of pretreatment prognostic factors in children with hepatoblastoma: A report from the children's oncology group
    • R. L. Meyers, J. R. Rowland, M. Krailo, Z. Chen, H. M. Katzenstein and M. H. Malogolowkin, Predictive power of pretreatment prognostic factors in children with hepatoblastoma: a report from the Children's Oncology Group, Pediatr Blood Cancer 53 (2009), 1016-1022.
    • (2009) Pediatr. Blood Cancer , vol.53 , pp. 1016-1022
    • Meyers, R.L.1    Rowland, J.R.2    Krailo, M.3    Chen, Z.4    Katzenstein, H.M.5    Malogolowkin, M.H.6
  • 244
    • 24944469682 scopus 로고    scopus 로고
    • Cytogenetic evaluation of a large series of hepatoblastomas: Numerical abnormalities with recurring aberrations involving 1q12-q21
    • G. E. Tomlinson, E. C. Douglass, B. H. Pollock, M. J. Finegold and N. R. Schneider, Cytogenetic evaluation of a large series of hepatoblastomas: numerical abnormalities with recurring aberrations involving 1q12-q21, Genes Chromosomes Cancer 44 (2005), 177-184.
    • (2005) Genes Chromosomes Cancer 44 , pp. 177-184
    • Tomlinson, G.E.1    Douglass, E.C.2    Pollock, B.H.3    Finegold, M.J.4    Schneider, N.R.5
  • 245
    • 0033900096 scopus 로고    scopus 로고
    • Characterization of genomic alterations in hepatoblastomas. A role for gains on chromosomes 8q and 20 as predictors of poor outcome
    • R. G. Weber, T. Pietsch, D. von Schweinitz and D. Lichter, Characterization of genomic alterations in hepatoblastomas. A role for gains on chromosomes 8q and 20 as predictors of poor outcome, Am J Pathol 157 (2000), 571-578.
    • (2000) Am. J. Pathol. , vol.157 , pp. 571-578
    • Weber, R.G.1    Pietsch, T.2    Von Schweinitz, D.3    Lichter, D.4
  • 247
    • 0025844921 scopus 로고
    • Consistent cytogenetic aberrations in hepatoblastoma: A common pathway of genetic alterations in embryonal liver and skeletal muscle malignancies
    • J. A. Fletcher, H. P. Kozakewich, K. Pavelka, H. E. Grier, R. C. Shamberger, B. Korf et al. , Consistent cytogenetic aberrations in hepatoblastoma: a common pathway of genetic alterations in embryonal liver and skeletal muscle malignancies? Genes Chromosomes Cancer 3 (1991), 37-43.
    • (1991) Genes Chromosomes Cancer , vol.3 , pp. 37-43
    • Fletcher, J.A.1    Kozakewich, H.P.2    Pavelka, K.3    Grier, H.E.4    Shamberger, R.C.5    Korf, B.6
  • 248
    • 0025953113 scopus 로고
    • Abnormalities of 2q: A common genetic link between rhabdomyosarcoma and hepatoblastoma
    • E. Rodriguez, V. E. Reuter, C. Mies, G. J. Bosl and R. S. Chaganti, Abnormalities of 2q: a common genetic link between rhabdomyosarcoma and hepatoblastoma? Genes Chromosomes Cancer 3 (1991), 122-127.
    • (1991) Genes Chromosomes Cancer , vol.3 , pp. 122-127
    • Rodriguez, E.1    Reuter, V.E.2    Mies, C.3    Bosl, G.J.4    Chaganti, R.S.5
  • 249
    • 0021932813 scopus 로고
    • Loss of heterozygosity in threeembryonal tumours suggests a common pathogenetic mechanism
    • A. Koufos,M. F. Hansen, N. G. Copeland, N. A. Jenkins, B. C. Lampkin and W. K. Cavenee, Loss of heterozygosity in threeembryonal tumours suggests a common pathogenetic mechanism, Nature 316 (1985), 330-334.
    • (1985) Nature , vol.316 , pp. 330-334
    • Koufosm. F Hansen, A.1    Copeland, N.G.2    Jenkins, N.A.3    Lampkin, B.C.4    Cavenee, W.K.5
  • 250
  • 251
    • 0030610260 scopus 로고    scopus 로고
    • Coding mutations in p57KIP2 are present in some cases of Beckwith-Wiedemann syndrome but are rare or absent in Wilms tumors
    • D. O'Keefe, D. Dao, L. Zhao, R. Sanderson, D. Warburton, L. Weiss et al. , Coding mutations in p57KIP2 are present in some cases of Beckwith-Wiedemann syndrome but are rare or absent in Wilms tumors, Am J Hum Genet 61 (1997), 295-303.
    • (1997) Am. J. Hum. Genet. , vol.61 , pp. 295-303
    • O'keefe, D.1    Dao, D.2    Zhao, L.3    Sanderson, R.4    Warburton, D.5    Weiss, L.6
  • 253
    • 0032790193 scopus 로고    scopus 로고
    • Major hepatectomy for hepatocellular carcinoma in patients with an unsatisfactory indocyanine green clearance test
    • C. M. Lam, S. T. Fan, C. M. Lo and J. Wong, Major hepatectomy for hepatocellular carcinoma in patients with an unsatisfactory indocyanine green clearance test, Br J Surg 86 (1999), 1012-1017.
    • (1999) Br. J. Surg. , vol.86 , pp. 1012-1017
    • Lam, C.M.1    Fan, S.T.2    Lo, C.M.3    Wong, J.4
  • 254
    • 0033815532 scopus 로고    scopus 로고
    • P57 KIP2 is not mutated in hepatoblastoma but shows increased transcriptional activity in a comparative analysis of the three imprinted genes p57 KIP2 IGF2, and H19
    • W. Hartmann, A. Waha, A. Koch, C. G. Goodyer, S. Albrecht, D. von Schweinitz et al. , p57(KIP2) is not mutated in hepatoblastoma but shows increased transcriptional activity in a comparative analysis of the three imprinted genes p57(KIP2), IGF2, and H19, Am J Pathol 157 (2000), 1393-1403.
    • (2000) Am. J. Pathol. , vol.157 , pp. 1393-1403
    • Hartmann, W.1    Waha, A.2    Koch, A.3    Goodyer, C.G.4    Albrecht, S.5    Von Schweinitz, D.6
  • 256
    • 0035886696 scopus 로고    scopus 로고
    • Methylation changes in the human igf2 p3 promoter parallel igf2 expression in the primary tumor established cell line and xenograft of a human hepatoblastoma
    • T. Eriksson, T. Frisk, S. G. Gray, D. von Schweinitz, T. Pietsch, C. Larsson et al. , Methylation changes in the human IGF2 p3 promoter parallel IGF2 expression in the primary tumor, established cell line, and xenograft of a human hepatoblastoma, Exp Cell Res 270 (2001), 88-95.
    • (2001) Exp. Cell Res. , vol.270 , pp. 88-95
    • Eriksson, T.1    Frisk, T.2    Gray, S.G.3    Von Schweinitz, D.4    Pietsch, T.5    Larsson, C.6
  • 258
    • 0035951687 scopus 로고    scopus 로고
    • Expression levels of insulin-like growth factor binding proteins and insulin receptor isoforms in hepatoblastomas
    • H. von Horn, M. Tally, K. Hall, T. Eriksson, T. J. Ekstrom and S. G. Gray, Expression levels of insulin-like growth factor binding proteins and insulin receptor isoforms in hepatoblastomas, Cancer Lett 162 (2001), 253-260.
    • (2001) Cancer Lett. , vol.162 , pp. 253-260
    • Von Horn, H.1    Tally, M.2    Hall, K.3    Eriksson, T.4    Ekstrom, T.J.5    Gray, S.G.6
  • 259
    • 0031757172 scopus 로고    scopus 로고
    • Overexpression of cyclin D1 and cdk4 in tumorigenesis of sporadic hepatoblastomas
    • H. Kim, E. K. Ham, Y. I. Kim, J. G. Chi, H. S. Lee, S. H. Park et al. , Overexpression of cyclin D1 and cdk4 in tumorigenesis of sporadic hepatoblastomas, Cancer Lett 131 (1998), 177-183.
    • (1998) Cancer Lett. , vol.131 , pp. 177-183
    • Kim, H.1    Ham, E.K.2    Kim, Y.I.3    Chi, J.G.4    Lee, H.S.5    Park, S.H.6
  • 262
    • 0038146961 scopus 로고    scopus 로고
    • Hypermethylation of the p16 gene and lack of p16 expression in hepatoblastoma
    • Y. H. Shim, H. J. Park, M. S. Choi, J. S. Kim, H. Kim, J. J. Kim et al. , Hypermethylation of the p16 gene and lack of p16 expression in hepatoblastoma, Mod Pathol 16 (2003), 430-436.
    • (2003) Mod. Pathol. , vol.16 , pp. 430-436
    • Shim, Y.H.1    Park, H.J.2    Choi, M.S.3    Kim, J.S.4    Kim, H.5    Kim, J.J.6
  • 263
    • 0036220817 scopus 로고    scopus 로고
    • Distinct patterns of p27/KIP 1 gene expression in hepatoblastoma and prognostic implications with correlation before and after chemotherapy
    • M. Brotto and M. J. Finegold, Distinct patterns of p27/KIP 1 gene expression in hepatoblastoma and prognostic implications with correlation before and after chemotherapy, Hum Pathol 33 (2002), 198-205.
    • (2002) Hum. Pathol. , vol.33 , pp. 198-205
    • Brotto, M.1    Finegold, M.J.2
  • 264
    • 0031841285 scopus 로고    scopus 로고
    • Expression of transforming growth factor-alpha in hepatoblastoma
    • A. Kiss, A. Szepesi, G. Lotz, P. Nagy and P. Schaff, Expression of transforming growth factor-alpha in hepatoblastoma, Cancer 83 (1998), 690-697.
    • (1998) Cancer , vol.83 , pp. 690-697
    • Kiss, A.1    Szepesi, A.2    Lotz, G.3    Nagy, P.4    Schaff, P.5
  • 265
    • 4644297399 scopus 로고    scopus 로고
    • High expression of telomerase is an independent prognostic indicator of poor outcome in hepatoblastoma
    • E. Hiyama, H. Yamaoka, T. Matsunaga, Y. Hayashi, H. Ando, S. Suita et al. , High expression of telomerase is an independent prognostic indicator of poor outcome in hepatoblastoma, Br J Cancer 91 (2004), 972-979.
    • (2004) Br. J. Cancer , vol.91 , pp. 972-979
    • Hiyama, E.1    Yamaoka, H.2    Matsunaga, T.3    Hayashi, Y.4    Ando, H.5    Suita, S.6
  • 267
    • 0034906471 scopus 로고    scopus 로고
    • Frequent deletions and mutations of the beta-catenin gene are associated with overexpression of cyclin d1 and fibronectin and poorly differentiated histology in childhood hepatoblastoma
    • H. Takayasu, H. Horie, E. Hiyama, T. Matsunaga, Y. Hayashi, Y. Watanabe et al. , Frequent deletions and mutations of the beta-catenin gene are associated with overexpression of cyclin D1 and fibronectin and poorly differentiated histology in childhood hepatoblastoma, Clin Cancer Res 7 (2001), 901-908.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 901-908
    • Takayasu, H.1    Horie, H.2    Hiyama, E.3    Matsunaga, T.4    Hayashi, Y.5    Watanabe, Y.6
  • 268
    • 0035066173 scopus 로고    scopus 로고
    • Nuclear localization of beta-catenin is an important prognostic factor in hepatoblastoma
    • W. S. Park, R. R. Oh, J. Y. Park, P. J. Kim, M. S. Shin, J. H. Lee et al. , Nuclear localization of beta-catenin is an important prognostic factor in hepatoblastoma, J Pathol 193 (2001), 483-490.
    • (2001) J. Pathol. , vol.193 , pp. 483-490
    • Park, W.S.1    Oh, R.R.2    Park, J.Y.3    Kim, P.J.4    Shin, M.S.5    Lee, J.H.6
  • 269
    • 67349272856 scopus 로고    scopus 로고
    • Histologic subtypes of hepatoblastoma are characterized by differential canonical Wnt andNotch pathway activation inDLK+ precursors
    • D. Lopez-Terrada, P. H. Gunaratne, A. M. Adesina, J. Pulliam, D. M. Hoang, Y. Nguyen et al. , Histologic subtypes of hepatoblastoma are characterized by differential canonical Wnt andNotch pathway activation inDLK+ precursors, Hum Pathol 40 (2009), 783-794.
    • (2009) Hum. Pathol. , vol.40 , pp. 783-794
    • Lopez-Terrada, D.1    Gunaratne, P.H.2    Adesina, A.M.3    Pulliam, J.4    Hoang, D.M.5    Nguyen, Y.6
  • 270
    • 0029979793 scopus 로고    scopus 로고
    • Somatic mutations of the apc gene in sporadic hepatoblastomas
    • H. Oda, Y. Imai, Y. Nakatsuru, J. Hata and J. Ishikawa, Somatic mutations of the APC gene in sporadic hepatoblastomas, Cancer Res 56 (1996), 3320-3323.
    • (1996) Cancer Res. , vol.56 , pp. 3320-3323
    • Oda, H.1    Imai, Y.2    Nakatsuru, Y.3    Hata, J.4    Ishikawa, J.5
  • 271
    • 0037130449 scopus 로고    scopus 로고
    • Mutational spectrum of beta-catenin AXIN1 and AXIN2 in hepatocellular carcinomas and hepatoblastomas
    • K. Taniguchi, L. R. Roberts, I. N. Aderca, X. Dong, C. Qian, L. M. Murphy et al. , Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas, Oncogene 21 (2002), 4863-4871.
    • (2002) Oncogene , vol.21 , pp. 4863-4871
    • Taniguchi, K.1    Roberts, L.R.2    Aderca, I.N.3    Dong, X.4    Qian, C.5    Murphy, L.M.6
  • 272
    • 20444466479 scopus 로고    scopus 로고
    • Elevated expression of Wnt antagonists is a common event in hepatoblastomas
    • A. Koch, A. Waha, W. Hartmann, A. Hrychyk, U. Schuller, U. Waha et al. , Elevated expression of Wnt antagonists is a common event in hepatoblastomas, Clin Cancer Res 11 (2005), 4295-4304.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 4295-4304
    • Koch, A.1    Waha, A.2    Hartmann, W.3    Hrychyk, A.4    Schuller, U.5    Waha, U.6
  • 273
    • 57049182539 scopus 로고    scopus 로고
    • Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer
    • S. Cairo, C. Armengol, A. De Reynies, Y. Wei, E. Thomas, C. A. Renard et al. , Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer, Cancer Cell 14 (2008), 471-484.
    • (2008) Cancer Cell , vol.14 , pp. 471-484
    • Cairo, S.1    Armengol, C.2    De Reynies, A.3    Wei, Y.4    Thomas, E.5    Renard, C.A.6


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