Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 11, 1996, Pages 5455-5459

  Bennicelli, Jeannette L ^a   Edwards, Robin H ^a   Barr, Frederic G ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

FKHR; fusion protein; PAX3; transcription factor

Indexed keywords

HYBRID PROTEIN; TRANSCRIPTION FACTOR;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CARCINOGENESIS; CHROMOSOME TRANSLOCATION; DNA BINDING; GENE EXPRESSION; GENE FUNCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RHABDOMYOSARCOMA; TRANSACTIVATION; TRANSCRIPTION REGULATION;

3T3 CELLS; ANIMALS; BASE SEQUENCE; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CHROMOSOMES, HUMAN, PAIR 13; CHROMOSOMES, HUMAN, PAIR 2; CLONING, MOLECULAR; DNA PRIMERS; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; FUNGAL PROTEINS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PAIRED BOX TRANSCRIPTION FACTORS; POLYMERASE CHAIN REACTION; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; RESTRICTION MAPPING; RHABDOMYOSARCOMA, ALVEOLAR; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE DELETION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TRANSLOCATION, GENETIC;

ANIMALIA;

EID: 0029980113     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.11.5455     Document Type: Article

References (22)

1. Turc-Carel, C., Lizard-Nacol, S., Justrabo, E., Favrot, M., Philip, T. & Tabone, E. (1986) Cancer Genet. Cytogenet. 19, 361-362.
2. Barr, F. G., Galili, N., Holick, J., Biegel, J. A., Rovera, G. & Emanuel, B. S. (1993) Nat. Genet. 3, 113-117.
3. Galili, N., Davis, R., Fredericks, W. J., Mukhopadhyay, S., Rauscher, F. J., III, Emanuel, B. S., Rovera, G. & Barr, F. G. (1993) Nat. Genet. 5, 230-235.
4. Goulding, M. D., Chalepakis, G., Deutsch, U., Erselius, J. R. & Gruss, P. (1991) EMBO J. 10, 1135-1147.
5. Bennicelli, J. L., Fredericks, W. J., Wilson, R. B., Rauscher, F. J., III, & Barr, F. G. (1995) Oncogene 11, 119-130.
6. Fredericks, W. J., Galili, N., Mukhopadhyay, S., Rovera, G., Bennicelli, J., Barr, F. G. & Rauscher, F. J., III (1995) Mol. Cell. Biol. 15, 1522-1535.
7. Sadowski, I. & Ptashne, M. (1989) Nucleic Acids Res. 17, 7539.
8. Lillie, J. W. & Green, M. R. (1989) Nature (London) 338, 39-44.
9. Chalepakis, G., Fritsch, R., Fickenscher, H., Deutsch, U., Goulding, M. & Gruss, P. (1991) Cell 66, 873-884.
10. Schafer, B. W., Czerny, T., Bernasconi, M., Genini, M. & Busslinger, M. (1994) Nucleic Acids Res. 22, 4574-4582.
11. Gorman, C, Moffat, L. F. & Howard, B. H. (1982) Mol. Cell. Biol. 2, 1044-1051.
12. Henthorn, P., Zervos, P., Raducha, M., Harris, H. & Kadesch, T. (1988) Proc. Natl. Acad. Sci. USA 85, 6342-6346.
13. Tremblay, P. & Gruss, P. (1994) Pharmacol. Ther. 61, 205-226.
14. Epstein, J. A., Lam, P., Jepeal, L., Maas, R. L. & Shapiro, D. N. (1995) J. Biol. Chem. 270, 11719-11722.
15. Chalepakis, G., Jones, F. S., Edelman, G. M. & Gruss, P. (1994) Proc. Natl. Acad. Sci. USA 91, 12745-12749.
16. Davis, R. J., D'Cruz, C. M., Lovell, M. A., Biegel, J. A. & Barr, F. G. (1994) Cancer Res. 54, 2869-2872.
17. Zappavigna, V., Sartori, D. & Mavilio, F. (1994) Genes Dev. 8, 732-744.
18. Baichwal, V. R. & Tjian, R. (1990) Cell 63, 815-825.
19. Johansen, F.-E. & Prywes, R. (1993) Mol. Cell. Biol. 13, 4640-4647.
20. Dubendorff, J. W., Whittaker, L. J., Eltman, J. T. & Lipsick, J. S. (1992) Genes Dev. 6, 2524-2535.
21. Brown, H. J., Sutherland, J. A., Cook, A., Bannister, A. J. & Kouzarides, T. (1995) EMBO J. 14, 124-131.
22. Pruitt, S. C. (1992) Development (Cambridge, U.K.) 116, 573-583.