High telomerase reverse transcriptase (hTERT) messenger RNA level correlates with tumor recurrence in patients with favorable histology Wilms' tumor

Cancer Research

Volumn 59, Issue 17, 1999, Pages 4301-4307

  Dome, Jeffrey S ^a,d   Chung, Seung ^a   Bergemann, Tracy ^b   Umbricht, Christopher B ^a   Saji, Motoyasu ^a   Carey, Lisa A ^a,e   Grundy, Paul E ^c   Perlman, Elizabeth J ^a   Breslow, Norman E ^b   Sukumar, Saraswati ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c CROSS CANCER INSTITUTE   (Canada)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MESSENGER RNA; RNA; TELOMERASE;

ARTICLE; CHILD; CHILDHOOD CANCER; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; INFANT; KIDNEY TUMOR; MAJOR CLINICAL STUDY; MALE; NEPHROBLASTOMA; NUCLEOTIDE SEQUENCE; PLOIDY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR RECURRENCE;

EID: 0033198499     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M. D., Ho, P. L., Coviello, G. M., Wright, W. E., Weinrich, S. L., and Shay, J. W. Specific association of human telomerase activity with immortal cells and cancer. Science (Washington DC), 206: 2011-2015, 1994.
2. Carey, L. A., Hedican, C., Henderson, G., Umbricht, C. B., Dome, J. S., Varon, D., and Sukumar, S. Careful histological confirmation and microdissection reveal telomerase activity in otherwise telomerase-negative breast cancers. Clin. Cancer Res., 4: 435-440, 1997.
3. Zhang, W. B., Kapusta, L. R., Slingerland, J. M., and Klotz, L. H. Telomerase activity in prostate cancer, prostatic intraepithelial neoplasia, and benign prostatic epithelium. Cancer Res., 58: 619-621, 1998.
4. Umbricht, C. B., Saji, M., Westra, W. H., Udelsman, R., Zeiger, M. A., and Sukumar, S. Telomerase activity: a marker to distinguish follicular thyroid adenoma from carcinoma. Cancer Res., 57: 2144-2147, 1997.
5. Kyo, S., Takamura, M., Tanaka, M., Kanaya, T., and Inoue, M. Telomerase activity in cervical cancer is quantitatively distinct from that in its precursor lesions. Int. J. Cancer, 79: 66-70, 1998.
6. Shroyer, K. R., Thompson, L. C., Enomoto, T., Eskens, J. L., Shroyer, A. L., and McGregor, J. A. Telomerase expression in normal epithelium, reactive atypia, squamous dysplasia, and squamous cell carcinoma of the uterine cervix. Am. J. Clin. Pathol., 109: 153-162, 1998.
7. Iwasaka, T., Zheng, P. S., Yokoyama, M., Fukuda, K., Nakao, Y., and Sugimori, H. Telomerase activation in cervical neoplasia. Obstet. Gynecol., 91: 260-262, 1998.
8. Poremba, C., Bocker, W., Willenbring, H., Schafer, K. L., Otterbach, F., Burger, H., Diallo, R., and Dockhorndwomiczak, B. Telomerase activity in human proliferative breast lesions. Int. J. Oncol., 12: 641-648, 1998.
9. Hiyama, E., Hiyama, K., Yokohama, T., Matsuura, Y., Piatyszek, M. A., and Shay, J. W. Correlating telomerase activity levels with human neuroblastoma outcomes. Nat. Med., 1: 249-255, 1995.
10. Hiyama, E., Hiyama, K., Ohtsu, K., Yamaoka, H., Ichikawa, T., Shay, J. W., and Yokoyama, T. Telomerase activity in neuroblastoma: is it a prognostic indicator of clinical behaviour? Eur. J. Cancer, 33: 1932-1936, 1997.
11. Hiyama, E., Yokoyama, T., Tatsumoto, N., Hiyama, K., Imamura, Y., Murakami, Y., Kodama, T., Piatyszek, M. A., Shay, J. W., and Matsuura, Y. Telomerase activity in gastric cancer. Cancer Res., 55: 3258-3262, 1995.
12. Okusa, Y., Shinomiya, N., Ichikura, T., and Mochizuki, H. Correlation between telomerase activity and DNA ploidy in gastric cancer. Oncology, 55: 258-264, 1998.
13. Clark, G. M., Osborne, C. K., Levitt, D., Wu, F., and Kim, N. W. Telomerase activity and survival of patients with node-positive breast cancer. J. Natl. Cancer Inst., 89: 1874-1881, 1997.
14. Xu, D., Gruber, A., Peterson, C., and Pisa, P. Telomerase activity and the expression of telomerase components in acute myelogenous leukaemia. Br. J. Haematol., 102: 1367-1375, 1998.
15. Bechter, O. E., Eisterer, W., Pall, G., Hilbe, W., Kuhr, T., Thomas, P. R., and Thaler, J. Telomere length and telomerase activity predict survival in patients with B cell chronic lymphocytic leukemia. Cancer Res., 58: 4918-4922, 1998.
16. Langford, L. A., Piatyszek, M. A., Xu, R., Schold, S. C. J., Wright, W. E., and Shay, J. W. Telomerase activity in ordinary meningiomas predicts poor outcome. Hum. Pathol., 28: 416-420, 1997.
17. Miller, R. W., Young, J. L. J., and Novakovic, B. Childhood cancer. Cancer (Phila.), 75: 395-405, 1995.
18. Green, D. M., D'Angio, G. J., Beckwith, J. B., Breslow, N. E., Grundy, P. E., Ritchey, M. L., and Thomas, P. R. Wilms tumor. CA Cancer J. Clin., 46: 46-63, 1996.
19. Prentice, R. L. A case-cohort design for epidemiologic cohort studies and disease prevention trials. Biometrika, 73: 1-11, 1986.
20. Kim, N. W., and Wu, F. Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP). Nucleic Acids Res., 25: 2595-2597, 1997.
21. Piatyszek, M. A., Kim, N. W., Weinrich, S. L., Hiyama, K., Hiyama, E., Wright, W. E., and Shay, J. W. Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP). Methods Cell Sci., 17: 1-15, 1995.
22. Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual, Ed. 2. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
23. Kilian, A., Bowtell, D. D. L., Abud, H., Hime, G. R., Venter, D. J., Keese, P. K., Duncan, E. L., Reddel, R. R., and Jefferson, R. A. Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types. Hum. Mol. Genet., 6: 2011-2019, 1997.
24. Cox, D. R. Regression models and life tables (with discussion). J. R. Stat. Soc., 34: 187-220, 1972.
25. Barlow, W. E. Robust variance estimation for the case-cohort design. Biometrics, 50: 1064-1072, 1994.
26. Green, D. M., Breslow, N. E., Beckwith, J. B., Finklestein, J. Z., Grundy, P., Thomas, P. R., Kim, T., Shochat, S., Haase, G., Ritchey, M. L., and Kelalis, P., and D'Angio, G. J. Effect of duration of treatment on treatment outcome and cost of treatment for Wilms' tumor: a report from the National Wilms' Tumor Study Group. J. Clin. Oncol., 16: 3744-3751, 1998.
27. Shamberger, R. C., Guthrie, K. A., Ritchey, M. L., Haase, G. M., Takashima, J., Beckwith, J. B., D'Angio, G. J., Green, D. M., and Breslow, N. E. Surgery-related factors and local recurrence of Wilms tumor in National Wilms Tumor Study-4. Ann. Surg., 229: 292-297, 1999.
28. Feng, J., Funk, W. D., Wang, S. S., Weinrich, S. L., Avilion, A. A., Chiu, C. P., Adams, R. R., Chang, E., Allsopp, R. C., and Yu, J. The RNA component of human telomerase. Science (Washington DC), 269: 1236-1241, 1995.
29. Avilion, A. A., Piatyszek, M. A., Gupta, J., Shay, J. W., Bacchetti, S., and Greider, C. W. Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues. Cancer Res., 56: 645-650, 1996.
30. Nakamura, T. M., Morin, G. B., Chapman, K. B., Weinrich, S. L., Andrews, W. H., Lingner, J., Harley, C. B., and Cech, T. R. Telomerase catalytic subunit homologs from fission yeast and human. Science (Washington DC), 277: 955-959, 1997.
31. Nakayama, J. I., Tahara, H., Tahara, E., Saito, M., Ito, K., Nakamura, H., Nakanishi, T., Ide, T., and Ishikawa, F. Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas. Nat. Genet., 18: 65-68, 1998.
32. Nakayama, J., Saito, M., Nakamura, H., Matsuura, A., and Ishikawa, F. TLPI: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family. Cell, 88: 875-884, 1997.
33. Takakura, M., Kyo, S., Kanaya, T., Tanaka, M., and Inoue, M. Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer. Cancer Res., 58: 1558-1561, 1998.
34. Blasco, M. A., Rizen, M., Greider, C. W., and Hanahan, D. Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis. Nat. Genet., 12: 200-204, 1996.
35. Yashima, K., Vuitch, F., Gazdar, A. F., and Fahey, T. J. Telomerase activity in benign and malignant thyroid diseases. Surgery (St. Louis), 122: 1141-1145, 1997.
36. Brinkschmidt, C., Poremba, C., Christiansen, H., Simon, R., Schafer, K. L., Terpe, H. J., Lampert, F., Boecker, W., and Dockhorndworniczak, B. Comparative genomic hybridization and telomerase activity analysis identify two biologically different groups of 4S neuroblastomas. Br. J. Cancer, 77: 2223-2229, 1998.
37. Zhang, W., Piatyszek, M. A., Kobayashi, T., Estey, E., Andreeff, M., Deisseroth, A. B., Wright, W. E., and Shay, J. W. Telomerase activity in human acute myelogenous leukemia: inhibition of telomerase activity by differentiation-inducing agents. Clin. Cancer Res., 2: 799-803, 1996.
38. Mehle, C., Piatyszek, M. A., Ljungberg, B., Shay, J. W., and Roos, G. Telomerase activity in human renal cell carcinoma. Oncogene, 13: 161-166, 1996.
39. Albanell, J., Lonardo, F., Rusch, V., Engelhardt, M., Langenfeld, J., Han, W., Klimstra, D., Venkatraman, E., Moore, M. S., and Dmitrovsky, E. High telomerase activity in primary lung cancers-association with increased cell proliferation rates and advanced pathologic stage. J. Natl. Cancer Inst., 89: 1609-1615, 1997.
40. Hoos, A., Hepp, H. H., Kaul, S., Ahlert, T., Bastert, G., and Wallwiener, D. Telomerase activity correlates with tumor aggressiveness and reflects therapy effect in breast cancer. Int. J. Cancer, 79: 8-12, 1998.
41. Harley, C. B. Telomere loss: mitotic clock or genetic time bomb. Mutat. Res., 256: 271-282, 1991.
42. Vaziri, H., Dragowska, W., Allsopp, R. C., Thomas, T. E., Harley, C. B., and Lansdorp, P. M. Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age. Proc. Natl. Acad. Sci. USA, 91: 9857-9860, 1994.
43. Chiu, C. P., Dragowska, W., Kim, N. W., Vaziri, H., Yui, J., Thomas, T. E., Harley, C. B., and Lansdorp, P. M. Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow. Stem Cells, 14: 239-248, 1996.
44. Wang, H., and Blackburn, E. H. De novo telomere addition by Tetrahymena telomerase in vitro. EMBO J., 16: 866-879, 1997.
45. Bednenko, J., Melek, M., Greene, E. C., and Shippen, D. E. Developmentally regulated initiation of DNA synthesis by telomerase: evidence for factor-assisted de novo telomere formation. EMBO J., 16: 2507-2518, 1997.
46. Kramer, K. M., and Haber, J. E. New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats. Genes Dev., 7: 2345-2356, 1993.
47. Kondo, S., Tanaka, Y., Kondo, Y., Hitomi, M., Barnett, G. H., Ishizaka, Y., Liu, J., Haqqi, T., Nishiyama, A., Villeponleau, B., Cowell, J. K., and Barna, B. P. Antisense telomerase treatment - induction of two distinct pathways: apoptosis and differentiation. FASEB J., 12: 801-811, 1998.
48. Harle-Bachor, C., and Boukamp, P. Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes. Proc. Natl. Acad. Sci. USA, 93: 6476-6481, 1996.
49. Kyo, S., Takakura, M., Kodama, T., and Inoue, M. Telomerase activity in human endometrium. Cancer Res., 57: 610-614, 1997.
50. Belair, C. D., Yeager, T. R., Lopez, P. M., and Reznikoff, C. A. Telomerase activity: a biomarker of cell proliferation, not malignant transformation. Proc. Natl. Acad. Sci. USA, 94: 13677-13682, 1997.
51. Bednarek, A. K., Sahin, A., Brenner, A. J., Johnston, D. A., and Aldaz, C. M. Analysis of telomerase activity levels in breast cancer: positive detection at the in situ breast carcinoma stage. Clin. Cancer Res., 3: 11-16, 1997.
52. Umbricht, C. B., Sherman, M., Dome, J. S., Carey, L. A., Marks, J., Kim, N. W., and Sukumar, S. Telomerase activity in ductal carcinoma in situ and invasive breast cancer. Oncogene, 18: 3407-3414, 1999.