Cytogenetic findings in 73 osteosarcoma specimens and a review of the literature

Cancer Genetics and Cytogenetics

Volumn 95, Issue 1, 1997, Pages 74-87

  Bridge, Julia A ^a,b,g   Nelson, Marilu ^a   McComb, Erin ^b   McGuire, Michael H ^c   Rosenthal, Howard ^d   Vergara, Gerardo ^d   Maale, Gerhard E ^e   Spanier, Suzanne ^f   Neff, James R ^a,b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Trinity Lutheran Hospital   (United States)

^e PRESBYTERIAN HOSPITAL OF DALLAS   (United States)

^f UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^g UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER GRADING; CHROMOSOME REARRANGEMENT; CYTOGENETICS; FEMALE; HUMAN; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; OSTEOSARCOMA; PRIORITY JOURNAL; REVIEW;

EID: 0030964763     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(96)00306-8     Document Type: Article

References (52)

1. Dahlin DC, Coventry MB (1967): Osteogenic sarcoma. A study of 600 cases. J Bone Joint Surg 49A:101-110.
2. Huvos AG (1991): Bone Tumors. Diagnosis, Treatment, and Prognosis. W.B. Saunders Co., Philadelphia.
3. Bridge JA (1993): Cytogenetics and molecular cytogenetic techniques in orthopaedic surgery. Curr Concepts Rev; J Bone Joint Surg 75A:606-614.
4. Sandberg M, Bridge JA (1994): The Cytogenetics of Bone and Soft Tissue Tumors. RG Landes Co., Austin.
5. Bridge JA (1996): Cytogenetics and experimental models of sarcomas. In: Current Opinion in Oncology. MD Abeloff, J Klastersky, eds. Current Science, Philadelphia, pp. 284-288.
6. Bridge JA (1996): Cytogenetics of soft tissue tumors. Cancer J 9:129-135.
7. Bridge JA, Örndal C (in press): Cytogenetic analysis of bone and joint neoplasms. In: Pathology of Bone and Joint Neoplasms. T Helliwell, ed. W.B. Saunders Co., Orlando.
8. Sinovic JF, Bridge JA, Neff JR (1992): Ring chromosome in parosteal osteosarcoma. Clinical and diagnostic significance. Cancer Genet Cytogenet 62:50-52.
9. Pfeifer FM, Bridge JA, Neff JR, Mouron BJ (1991): Cytogenetic findings in aneurysmal bone cysts. Genes Chromosom Cancer 3:416-419.
10. Kurt AM, Unni KK, McLeod RA, Pritchard DJ (1990): Low-grade intraosseous osteosarcoma. Cancer 65:1418-1428.
11. ISCN (1995): An International System for Human Cytogenetic Nomenclature. F Mitelman, ed. S. Karger, Basel.
12. Castedo SMMJ, Seruca R, Oosterhuis JW, de Jong B, Koops HS, Leeuw JA (1988): Cytogenetics of a case of osteosarcoma. Cancer Genet Cytogenet 32:149-151.
13. Pearson ADJ, Reid MM, Davison EV, Bown N, Malcolm AJ, Craft AW (1988): Cytogenetic investigations of solid tumours of children. Arch Dis Child 63:1012-1015.
14. Biegel JA, Womer RB, Emmanuel BS (1989): Complex karyotypes in a series of pediatric osteosarcomas. Cancer Genet Cytogenet 38:89-100.
15. Tarkkanen M, Kaipainen A, Kataharju E, Böhling T, Szymanska J, Heliö H, Kivioja A, Elomaa I, Knuutila S (1993): Cytogenetic study of 249 consecutive patients examined for a bone tumor. Cancer Genet Cytogenet 68:1-21.
16. Mertens F, Mandahl N, Örndal C, Baldetorp B, Bauer HCF, Rydholm A, Wiebe T, Willén H, Akerman M, Heim S, Mitelman F (1993): Cytogenetic findings in 33 osteosarcomas. Int J Cancer 55:44-50.
17. Schwartz HS, Allen GA, Chudoba I, Butler MG (1992): Cytogenetic abnormalities in a rare case of giant cell osteogenic sarcoma. Cancer Genet Cytogenet 58:60-65.
18. Ozisik YY, Meloni AM, Zalupski MM, Ryan JR, Qureshi F, Sandberg AA (1993): Deletion of chromosome 13 in osteosarcoma secondary to irradiation. Cancer Genet Cytogenet 69:335-337.
19. Ozisik YY, Meloni AM, Peier A, Altungoz O, Spanier SS, Zalupski MM, Leong SPL, Sandberg AA (1994): Cytogenetic findings in 19 malignant bone tumors. Cancer 74:2268-2275.
20. Fletcher JA, Gebhardt MC, Kozakewich HP (1994): Cytogenetic aberrations in osteosarcomas. Nonrandom deletions, rings and double-minute chromosomes. Cancer Genet Cytogenet 77:81-88.
21. Hoogerwerf WA, Hawkins AL, Perlman EJ, Griffin CA (1994): Chromosome analysis of nine osteosarcomas. Genes Chromosom Cancer 9:88-92.
22. Bridge JA, Bhatia PS, Anderson JR, Neff JR (1993): Biologic and clinical significance of cytogenetic and molecular cytogenetic abnormalities in benign and malignant cartilaginous lesions. Cancer Genet Cytogenet 69:79-90.
23. Toguchida J, Ishizaki K, Nakamura Y, Sasaki MS, Ikenaga M, Kata M, Sugimoto M, Kotoura Y, Yamamuro T (1989): Assignment of common allele loss in osteosarcoma to the subregion 17p13. Cancer Res 49:6247-6251.
24. Miller CW, Aslo A, Tsay C, Slamon D, Ishizaki K, Toguchida H, Yamamuro T, Lampkin B, Koeffler HP (1990): Frequency and structure of p53 rearrangements in human osteosarcoma. Cancer Res 50:7950-7954.
25. Toguchida H, Yamaguchi T. Ritchie B, Beauchamp R, Dayton SH, Herrara GE, Yamamuro T, Kotoura Y. Sasaki MS, Little JB. Wechselbaum R, Ishizaki K, Yandell DW (1992): Mutation spectrum of the p53 gene in bone and soft tissue sarcomas. Cancer Res 52:6194-6199.
26. Malkin D, Li FP, Strong LC, Fraumeni JF, Nelson CE, Kim DH, Kassel J, Gryka MA. Bischoff FZ, Tainsky MA, Friend SH (1990): Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250:1233-1238.
27. Dryja TP, Rapaport JM, Epstein J, Goorin AM, Weichelbaum R, Koufos A, Cavenee WK (1986): Chromosome 13 homozygosity in osteosarcoma without retinoblastoma. Am J Hum Genet 38:59-66.
28. Wadayama B, Toguchida J, Shimizu T, Ishizaki K, Sasaki MS, Kotoura Y, Yamamuro T (1994): Mutation spectrum of the retinoblastoma gene in osteosarcomas. Cancer Res 54:3042-3048.
29. Heim S. Mitelman F (1995): Cancer Cytogenetics. Wiley-Liss, New York.
30. Tarkkanen M, Karhu R. Kallioniemi A. Elomaa I. Kivioja AH, Nevalainen J, Böhling T, Karaharju E, Hyytinen E, Knuutila S. Kallioniemi O-P (1995): Gains and losses of DNA sequences in osteosarcomas by comparative genomic hybridization. Cancer Res 55:1334-1338.
31. Ladanyi M, Cha C, Lewis R, Jhanwar SC, Huvos AG, Healey JH (1993): MDM2 gene amplification in metastatic osteosarcoma. Cancer Res 53:16-18.
32. Oliner JD, Kinzler KW, Meltzer PS, George DL, Vogelstein B (1992): Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 358:80-83.
33. Khatib ZA, Matsushime H, Valentine M, Shapiro DN, Sherr CJ, Look AT (1993): Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas. Cancer Res 53:5535-5541.
34. Roberts WM, Douglass EC, Peiper SC, Houghton PJ, Look AT (1989): Amplification of the gli gene in childhood sarcomas. Cancer Res 49:5407-5413.
35. Forus A, Olde Weghuis D, Smeets D, Fodstad O, Myklebost O, Geurts van Kessel A (1995): Comparative genomic: hybridization analysis of human sarcomas: II. Identification of novel amplicons at 6p and 17p in osteosarcomas. Genes Chromosom Cancer 14:15-21.
36. (1991): Human gene mapping 11. Cytogenet Cell Genet 58:1161-1163.
37. Craig I, Gemmill R, Kucherlapati R (1992): Report of the first international workshop on human chromosome 12 mapping. Cytogenet Cell Genet 61:243-251.
38. Jansson DS, Radosevich JA, Carney WP, Rosen ST, Schlom J. Storen ED, Hyser MJ, Gould VE (1990): An immunohistochemical analysis of ras oncogene expression in epithelial neoplasms of the colon. Cancer 65:1329-1337.
39. Bland KI, Konstadoulakis MM, Vezeridis MP, Wanebo HJ (1995): Oncogene protein co-expression. Value of Ha-ras, c-myc, c-fos and p53 as prognostic discriminants for breast carcinoma. Ann Surg 221:706-718.
40. Motojima K, Urano T, Nagata Y, Shiku H, Tsurifune T, Kanematsu T (1993): Detection of point mutations in the Kirstenras oncogene provides evidence for the multicentricity of pancreatic; carcinoma. Ann Surg 217:138-143.
41. Konishi N, Enomoto T, Buzard G, Ohshima M, Ward JM, Rice JM (1992): K-ras activation and ras p21 expression in latent prostatic carcinoma in Japanese men. Cancer 69:2293-2299.
42. Harada M, Dosaka-Akita H, Miyamoto H, Kuzumaki N, Kawakami Y (1992): Prognostic significance of the expression of ras oncogene product in non-small cell lung cancer. Cancer 69:72-77.
43. Barrios C, Castresana JS, Ruiz J, Kreicnergs A (1993): Amplification of c-myc oncogene and absence of c-Ha-ras point mutation in human bone sarcoma. J Ortho Res 11:556-563.
44. Cui LX, Oka T, Dobashi Y, Ishida T, Machimani L (1991): Mutational activation of K-ras gene is absent in human osteosarcoma. Med Sci Res 19:697-698.
45. Antillon-Klussmann F, Garcia-Delgado M, Villa-Elizaga I, Sierrasesumaga L (1995): Mutational activation of ras genes is absent in pediatric osteosarcoma. Cancer Genet Cytogenet 79:49-53.
46. Bridge JA, Neff JR, Mouron BS (1992): Giant cell tumor of bone. Chromosomal analysis of 48 specimens and review of the literature. Cancer Genet Cytogenet 58:2-13.
47. McComb E, Johansson SL, Neff JR, Nelson M, Bridge JA (1996): Chromosomal anomalies exclusive of telomeric associations in giant cell tumor of bone. Cancer Genet Cytogenet 88:163-166.
48. Sciot R, Samson I, Dal Cin P, Lateur L, Van Damme B, Van den Berghe H, Desmet V (1995): Giant cell rich parosteal osteosarcoma, Histopathology 27:51-55.
49. Hatada EN, Nieters A, Wulczvn FG, Naumann M, Meyer R, Nucifora G, McKeithan TW, Scheidereit C (1992): The ankyrin repeat domains of the NF-kβ precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kβ DNA hinding. Proc Natl Acad Sci USA 89:2489-2493.
50. Fujii D, Brissenden JE, Derynck R, Francke U (1986): Transforming growth factor beta gene maps to human chromosome 19 long arm and to mouse chromosome 7. Som Cell Mol Genet 12:281-286.
51. Bridge JA, Neff JR (1991): Cytogenetics of 226 bone lesions: Pathogenetic, diagnostic and clinical relevance. Am J Hum Genet 49:239.
52. Szymanska J, Mandahl N, Mertens F, Tarkkanen M, Karaharju E, Knuutila S (1996): Ring chromosomes in parosteal osteosarcoma gcontain sequences from 12q13-15: A combined cytogenetic and comparative genomic hybridization study. Genes Chromosom Cancer 16:31-34.