Live-cell imaging of tumor proteolysis: Impact of cellular and non-cellular microenvironment

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1824, Issue 1, 2012, Pages 123-132

  Rothberg, Jennifer M ^a,b   Sameni, Mansoureh ^b   Moin, Kamiar ^a,b   Sloane, Bonnie F ^a,b  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

3D culture; Functional imaging; Lysosomal proteases; Organotypic models; Proteolytic networks; Tumor microenvironment

Indexed keywords

COLLAGENASE 3; CYSTEINE PROTEINASE; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE 14; STROMELYSIN 3; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

BREAST CANCER; CELL INTERACTION; HUMAN; IMAGING SYSTEM; IN VIVO STUDY; INFLAMMATORY CELL; INTRADUCTAL CARCINOMA; LYSOSOME; PRECANCER; PRIORITY JOURNAL; PROTEIN DEGRADATION; QUANTITATIVE ANALYSIS; REVIEW; TUMOR CELL; TUMOR GROWTH; TUMOR MICROENVIRONMENT;

ANIMALS; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CELLS, CULTURED; CELLULAR MICROENVIRONMENT; DIAGNOSTIC IMAGING; FEMALE; HUMANS; MICROSCOPY, VIDEO; MODELS, BIOLOGICAL; NEOPLASMS; PROTEOLYSIS; SINGLE-CELL ANALYSIS; TUMOR MICROENVIRONMENT;

EID: 82755189529     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2011.07.025     Document Type: Review

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