-
1
-
-
4043122563
-
Bioinformatics of proteases in the MEROPS database
-
Barrett, A.J. (2004). Bioinformatics of proteases in the MEROPS database. Curr. Opin. Drug Discov. Dev. 7, 334-341.
-
(2004)
Curr. Opin. Drug Discov. Dev.
, vol.7
, pp. 334-341
-
-
Barrett, A.J.1
-
2
-
-
32344435145
-
Interplay of human tissue kallikrein 4 (hK4) with the plasminogen activation system: Hk4 regulates the structure and functions of the urokinase-type plasminogen activator receptor (uPAR)
-
Beaufort, N., Debela, M., Creutzburg, S., Kellermann, J., Bode, W., Schmitt, M., Pidard, D., and Magdolen, V. (2006). Interplay of human tissue kallikrein 4 (hK4) with the plasminogen activation system: hK4 regulates the structure and functions of the urokinase-type plasminogen activator receptor (uPAR). Biol. Chem. 387, 217-222.
-
(2006)
Biol. Chem.
, vol.387
, pp. 217-222
-
-
Beaufort, N.1
Debela, M.2
Creutzburg, S.3
Kellermann, J.4
Bode, W.5
Schmitt, M.6
Pidard, D.7
Magdolen, V.8
-
3
-
-
34247257873
-
The a and b subunits of the metalloprotease meprin are expressed in separate layers of human epidermis, revealing different functions in keratinocyte proliferation and differentiation
-
Becker-Pauly, C., Howel, M., Walker, T., Vlad, A., Aufenvenne, K., Oji, V., Lottaz, D., Sterchi, E.E., Debela, M., Magdolen, V., et al. (2007). The a and b subunits of the metalloprotease meprin are expressed in separate layers of human epidermis, revealing different functions in keratinocyte proliferation and differentiation. J. Invest. Dermatol. 127, 1115-1125.
-
(2007)
J. Invest. Dermatol.
, vol.127
, pp. 1115-1125
-
-
Becker-Pauly, C.1
Howel, M.2
Walker, T.3
Vlad, A.4
Aufenvenne, K.5
Oji, V.6
Lottaz, D.7
Sterchi, E.E.8
Debela, M.9
Magdolen, V.10
-
4
-
-
8144222388
-
The emerging roles of human tissue kallikreins in cancer
-
Borgono, C.A. and Diamandis, E.P. (2004). The emerging roles of human tissue kallikreins in cancer. Nat. Rev. Cancer 4, 876-890.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 876-890
-
-
Borgono, C.A.1
Diamandis, E.P.2
-
5
-
-
16844386886
-
Plasminogen activation and cancer
-
Dano, K., Behrendt, N., Hoyer-Hansen, G., Johnsen, M., Lund, L.R., Ploug, M., and Romer, J. (2005). Plasminogen activation and cancer. Thromb. Haemost. 93, 676-681.
-
(2005)
Thromb. Haemost.
, vol.93
, pp. 676-681
-
-
Dano, K.1
Behrendt, N.2
Hoyer-Hansen, G.3
Johnsen, M.4
Lund, L.R.5
Ploug, M.6
Romer, J.7
-
6
-
-
33748644034
-
Crystal structures of human tissue kallikrein 4: Activity modulation by a specific zinc binding site
-
Debela, M., Magdolen, V., Grimminger, V., Sommerhoff, C., Messerschmidt, A., Huber, R., Friedrich, R., Bode, W., and Goettig, P. (2006a). Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site. J. Mol. Biol. 362, 1094-1107.
-
(2006)
J. Mol. Biol.
, vol.362
, pp. 1094-1107
-
-
Debela, M.1
Magdolen, V.2
Grimminger, V.3
Sommerhoff, C.4
Messerschmidt, A.5
Huber, R.6
Friedrich, R.7
Bode, W.8
Goettig, P.9
-
7
-
-
33748646005
-
Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences
-
Debela, M., Magdolen, V., Schechter, N., Valachova, M., Lottspeich, F., Craik, C.S., Choe, Y., Bode, W., and Goettig, P. (2006b). Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences. J. Biol. Chem. 281, 25678-25688.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 25678-25688
-
-
Debela, M.1
Magdolen, V.2
Schechter, N.3
Valachova, M.4
Lottspeich, F.5
Craik, C.S.6
Choe, Y.7
Bode, W.8
Goettig, P.9
-
8
-
-
34848908980
-
Structural basis of the zinc inhibition of human tissue kallikrein 5
-
Debela, M., Goettig, P., Magdolen, V., Huber, R., Schechter, N.M., and Bode, W. (2007). Structural basis of the zinc inhibition of human tissue kallikrein 5. J. Mol. Biol. 373, 1017-1031.
-
(2007)
J. Mol. Biol.
, vol.373
, pp. 1017-1031
-
-
Debela, M.1
Goettig, P.2
Magdolen, V.3
Huber, R.4
Schechter, N.M.5
Bode, W.6
-
9
-
-
47549096054
-
Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7
-
Debela, M., Beaufort, N., Magdolen, V., Schechter, N.M., Craik, C.S., Schmitt, M., Bode, W., and Goettig, P. (2008). Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7. Biol. Chem. 389, 623-632.
-
(2008)
Biol. Chem.
, vol.389
, pp. 623-632
-
-
Debela, M.1
Beaufort, N.2
Magdolen, V.3
Schechter, N.M.4
Craik, C.S.5
Schmitt, M.6
Bode, W.7
Goettig, P.8
-
10
-
-
75149146475
-
Potential role of multiple members of the kallikrein-related peptidase family of serine proteases in activating latent TGFb1 in semen
-
Emami, N. and Diamandis, E.P. (2010). Potential role of multiple members of the kallikrein-related peptidase family of serine proteases in activating latent TGFb1 in semen. Biol. Chem. 391, 85-95.
-
(2010)
Biol. Chem.
, vol.391
, pp. 85-95
-
-
Emami, N.1
Diamandis, E.P.2
-
11
-
-
0141757365
-
Matrix metalloproteinases and tumor progression
-
Freije, J.M., Balbin, M., Pendas, A.M., Sanchez, L.M., Puente, X.S., and Lopez-Otin, C. (2003). Matrix metalloproteinases and tumor progression. Adv. Exp. Med. Biol. 532, 91-107.
-
(2003)
Adv. Exp. Med. Biol.
, vol.532
, pp. 91-107
-
-
Freije, J.M.1
Balbin, M.2
Pendas, A.M.3
Sanchez, L.M.4
Puente, X.S.5
Lopez-Otin, C.6
-
12
-
-
0030975940
-
Prostatic kallikrein hK2, but not prostate-specific antigen (hK3), activates single-chain urokinase-type plasminogen activator
-
Frenette, G., Tremblay, R.R., Lazure, C., and Dube, J.Y. (1997). Prostatic kallikrein hK2, but not prostate-specific antigen (hK3), activates single-chain urokinase-type plasminogen activator. Int. J. Cancer 71, 897-899.
-
(1997)
Int. J. Cancer
, vol.71
, pp. 897-899
-
-
Frenette, G.1
Tremblay, R.R.2
Lazure, C.3
Dube, J.Y.4
-
13
-
-
0037178833
-
The structure of human prokallikrein 6 reveals a novel activation mechanism for the kallikrein family
-
Gomis-Rüth, F.X., Bayés, A., Sotiropoulou, G., Pampalakis, G., Tsetsenis, T., Villegas, V., Avilés, F.X., and Coll, M. (2002). The structure of human prokallikrein 6 reveals a novel activation mechanism for the kallikrein family. J. Biol. Chem. 277, 27273-27281.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27273-27281
-
-
Gomis-Rüth, F.X.1
Bayés, A.2
Sotiropoulou, G.3
Pampalakis, G.4
Tsetsenis, T.5
Villegas, V.6
Avilés, F.X.7
Coll, M.8
-
14
-
-
47549113638
-
Kallikreins and proteinase-mediated signaling: Proteinase-activated receptors (PARs) and the pathophysiology of inflammatory diseases and cancer
-
Hollenberg, M.D., Oikonomopoulou, K., Hansen, K.K., Saifeddine, M., Ramachandran, R., and Diamandis, E.P. (2008). Kallikreins and proteinase-mediated signaling: proteinase-activated receptors (PARs) and the pathophysiology of inflammatory diseases and cancer. Biol. Chem. 389, 643-651.
-
(2008)
Biol. Chem.
, vol.389
, pp. 643-651
-
-
Hollenberg, M.D.1
Oikonomopoulou, K.2
Hansen, K.K.3
Saifeddine, M.4
Ramachandran, R.5
Diamandis, E.P.6
-
15
-
-
0037509851
-
Matrix metalloproteinases in cancer
-
Itoh, Y. and Nagase, H. (2002). Matrix metalloproteinases in cancer. Essays Biochem. 38, 21-36.
-
(2002)
Essays Biochem.
, vol.38
, pp. 21-36
-
-
Itoh, Y.1
Nagase, H.2
-
16
-
-
0031010461
-
Matrix metalloproteinases 1 and 3, tissue inhibitor of metalloproteinase-1 and the complex of metalloproteinase-1/ tissue inhibitor in plasma of patients with prostate cancer
-
Jung, K., Nowak, L., Lein, M., Priem, F., Schnorr, D., and Loening, S.A. (1997). Matrix metalloproteinases 1 and 3, tissue inhibitor of metalloproteinase-1 and the complex of metalloproteinase-1/ tissue inhibitor in plasma of patients with prostate cancer. Int. J. Cancer 74, 220-223.
-
(1997)
Int. J. Cancer
, vol.74
, pp. 220-223
-
-
Jung, K.1
Nowak, L.2
Lein, M.3
Priem, F.4
Schnorr, D.5
Loening, S.A.6
-
17
-
-
57649155302
-
Proteases: Multifunctional enzymes in life and disease
-
Lopez-Otin, C. and Bond, J.S. (2008). Proteases: multifunctional enzymes in life and disease. J. Biol. Chem. 283, 30433-30437.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 30433-30437
-
-
Lopez-Otin, C.1
Bond, J.S.2
-
18
-
-
77951479269
-
Analyzing the protease web in skin: Meprin metalloproteases are activated specifically by KLK4, 5 and 8 vice versa leading to processing of proKLK7 thereby triggering its activation
-
Ohler, A., Debela, M., Wagner, S., Magdolen, V., and Becker-Pauly, C. (2010). Analyzing the protease web in skin: meprin metalloproteases are activated specifically by KLK4, 5 and 8 vice versa leading to processing of proKLK7 thereby triggering its activation. Biol. Chem. 391, 455-460.
-
(2010)
Biol. Chem.
, vol.391
, pp. 455-460
-
-
Ohler, A.1
Debela, M.2
Wagner, S.3
Magdolen, V.4
Becker-Pauly, C.5
-
19
-
-
34548242780
-
Tissue kallikrein proteolytic cascade pathways in normal physiology and cancer
-
Pampalakis, G. and Sotiropoulou, G. (2007). Tissue kallikrein proteolytic cascade pathways in normal physiology and cancer. Biochim. Biophys. Acta 1776, 22-31.
-
(2007)
Biochim. Biophys. Acta
, vol.1776
, pp. 22-31
-
-
Pampalakis, G.1
Sotiropoulou, G.2
-
20
-
-
45549086117
-
Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression
-
Ramsay, A.J., Dong, Y., Hunt, M.L., Linn, M., Samaratunga, H., Clements, J.A., and Hooper, J.D. (2008). Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression. J. Biol. Chem. 283, 12293-12304.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 12293-12304
-
-
Ramsay, A.J.1
Dong, Y.2
Hunt, M.L.3
Linn, M.4
Samaratunga, H.5
Clements, J.A.6
Hooper, J.D.7
-
21
-
-
34547469532
-
Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (Auto-)catalytic activation and resistance to inhibition by TIMP-1
-
Ries, C., Pitsch, T., Mentele, R., Zahler, S., Egea, V., Nagase, H., and Jochum, M. (2007). Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (auto-)catalytic activation and resistance to inhibition by TIMP-1. Biochem. J. 405, 547-558.
-
(2007)
Biochem. J.
, vol.405
, pp. 547-558
-
-
Ries, C.1
Pitsch, T.2
Mentele, R.3
Zahler, S.4
Egea, V.5
Nagase, H.6
Jochum, M.7
-
22
-
-
0031665794
-
Human kallikrein 2 (hK2) and prostate-specific antigen (PSA): Two closely related, but distinct, kallikreins in the prostate
-
Rittenhouse, H.G., Finlay, J.A., Mikolajczyk, S.D., and Partin, A.W. (1998). Human kallikrein 2 (hK2) and prostate-specific antigen (PSA): two closely related, but distinct, kallikreins in the prostate. Crit. Rev. Clin. Lab. Sci. 35, 275-368.
-
(1998)
Crit. Rev. Clin. Lab. Sci.
, vol.35
, pp. 275-368
-
-
Rittenhouse, H.G.1
Finlay, J.A.2
Mikolajczyk, S.D.3
Partin, A.W.4
-
23
-
-
0038655332
-
Porcine kallikrein-4 activation, glycosylation, activity, and expression in prokaryotic and eukaryotic hosts
-
Ryu, O., Hu, J.C., Yamakoshi, Y., Villemain, J.L., Cao, X., Zhang, C., Bartlett, J.D., and Simmer, J.P. (2002). Porcine kallikrein-4 activation, glycosylation, activity, and expression in prokaryotic and eukaryotic hosts. Eur. J. Oral Sci. 110, 358-365.
-
(2002)
Eur. J. Oral Sci.
, vol.110
, pp. 358-365
-
-
Ryu, O.1
Hu, J.C.2
Yamakoshi, Y.3
Villemain, J.L.4
Cao, X.5
Zhang, C.6
Bartlett, J.D.7
Simmer, J.P.8
-
24
-
-
34547634419
-
Distribution of 15 human kallikreins in tissues and biological fluids
-
Shaw, J.L. and Diamandis, E.P. (2007). Distribution of 15 human kallikreins in tissues and biological fluids. Clin. Chem. 53, 1423-1432.
-
(2007)
Clin. Chem.
, vol.53
, pp. 1423-1432
-
-
Shaw, J.L.1
Diamandis, E.P.2
-
25
-
-
0035211252
-
The uPA/uPA receptor system as a target for tumor therapy
-
Sperl, S., Mueller, M.M., Wilhelm, O.G., Schmitt, M., Magdolen, V., and Moroder, L. (2001). The uPA/uPA receptor system as a target for tumor therapy. Drug News Perspect. 14, 401-411.
-
(2001)
Drug News Perspect.
, vol.14
, pp. 401-411
-
-
Sperl, S.1
Mueller, M.M.2
Wilhelm, O.G.3
Schmitt, M.4
Magdolen, V.5
Moroder, L.6
-
26
-
-
0030779820
-
Characterization of the precursor of prostate-specific antigen. Activation by trypsin and by human glandular kallikrein
-
DOI 10.1074/jbc.272.34.21582
-
Takayama, T.K., Fujikawa, K., and Davie, E.W. (1997). Characterization of the precursor of prostate-specific antigen. Activation by trypsin and by human glandular kallikrein. J. Biol. Chem. 272, 21582-21588. (Pubitemid 27374034)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.34
, pp. 21582-21588
-
-
Takayama, T.K.1
Fujikawa, K.2
Davie, E.W.3
-
27
-
-
0035909802
-
Characterization of hK4 (prostase), a prostate-specific serine protease: Activation of the precursor of prostate specific antigen (pro-PSA) and single-chain urokinase-type plasminogen activator and degradation of prostatic acid phosphatase
-
Takayama, T.K., McMullen, B.A., Nelson, P.S., Matsumura, M., and Fujikawa, K. (2001). Characterization of hK4 (prostase), a prostate-specific serine protease: activation of the precursor of prostate specific antigen (pro-PSA) and single-chain urokinase-type plasminogen activator and degradation of prostatic acid phosphatase. Biochemistry 40, 15341-15348.
-
(2001)
Biochemistry
, vol.40
, pp. 15341-15348
-
-
Takayama, T.K.1
McMullen, B.A.2
Nelson, P.S.3
Matsumura, M.4
Fujikawa, K.5
-
28
-
-
66149139853
-
DPPI may activate KLK4 during enamel formation
-
Tye, C.E., Pham, C.T., Simmer, J.P., and Bartlett, J.D. (2009). DPPI may activate KLK4 during enamel formation. J. Dent. Res. 88, 323-327.
-
(2009)
J. Dent. Res.
, vol.88
, pp. 323-327
-
-
Tye, C.E.1
Pham, C.T.2
Simmer, J.P.3
Bartlett, J.D.4
-
29
-
-
36148969695
-
Activation profiles and regulatory cascades of the human kallikrein-related peptidases
-
Yoon, H., Laxmikanthan, G., Lee, J., Blaber, S.I., Rodriguez, A., Kogot, J.M., Scarisbrick, I.A., and Blaber, M. (2007). Activation profiles and regulatory cascades of the human kallikrein-related peptidases. J. Biol. Chem. 282, 31852-31864.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 31852-31864
-
-
Yoon, H.1
Laxmikanthan, G.2
Lee, J.3
Blaber, S.I.4
Rodriguez, A.5
Kogot, J.M.6
Scarisbrick, I.A.7
Blaber, M.8
-
30
-
-
55549094116
-
Activation profiles of human kallikrein-related peptidases by proteases of the thrombostasis axis
-
Yoon, H., Blaber, S.I., Evans, D.M., Trim, J., Juliano, M.A., Scarisbrick, I.A., and Blaber, M. (2008). Activation profiles of human kallikrein-related peptidases by proteases of the thrombostasis axis. Protein Sci. 17, 1998-2007.
-
(2008)
Protein Sci.
, vol.17
, pp. 1998-2007
-
-
Yoon, H.1
Blaber, S.I.2
Evans, D.M.3
Trim, J.4
Juliano, M.A.5
Scarisbrick, I.A.6
Blaber, M.7
-
31
-
-
64849117485
-
A completed KLK activome profile: Investigation of activation profiles of KLK9, 10, and 15
-
Yoon, H., Blaber, S.I., Debela, M., Goettig, P., Scarisbrick, I.A., and Blaber, M. (2009). A completed KLK activome profile: investigation of activation profiles of KLK9, 10, and 15. Biol. Chem. 390, 373-377.
-
(2009)
Biol. Chem.
, vol.390
, pp. 373-377
-
-
Yoon, H.1
Blaber, S.I.2
Debela, M.3
Goettig, P.4
Scarisbrick, I.A.5
Blaber, M.6
|