메뉴 건너뛰기




Volumn 95, Issue 4, 2011, Pages 649-662

On the development of markers for pathological TDP-43 in amyotrophic lateral sclerosis with and without dementia

Author keywords

" Two axes" model; Amyotrophic lateral sclerosis; Biomarker; Frontotemporal lobar degeneration; TDP 43

Indexed keywords

ALPHA SYNUCLEIN; BIOLOGICAL MARKER; TAR DNA BINDING PROTEIN; TAU PROTEIN; UBIQUITIN;

EID: 82755189310     PISSN: 03010082     EISSN: 18735118     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2011.08.011     Document Type: Review
Times cited : (47)

References (221)
  • 8
    • 49249118746 scopus 로고    scopus 로고
    • TDP-43 is a culprit in human neurodegeneration, and not just an innocent bystander
    • Banks G.T., Kuta A., Isaacs A.M., Fisher E.M.C. TDP-43 is a culprit in human neurodegeneration, and not just an innocent bystander. Mamm. Genome 2008, 19:299-305.
    • (2008) Mamm. Genome , vol.19 , pp. 299-305
    • Banks, G.T.1    Kuta, A.2    Isaacs, A.M.3    Fisher, E.M.C.4
  • 13
    • 33750959751 scopus 로고    scopus 로고
    • Comparison of the growth hormone, IGF-1 and insulin in cerebrospinal fluid and serum between patients with motor neuron disease and healthy controls
    • Bilic E., Bilic E., Rudan I., Kusec V., Zurak N., Delimar D., Zagar M. Comparison of the growth hormone, IGF-1 and insulin in cerebrospinal fluid and serum between patients with motor neuron disease and healthy controls. Eur. J. Neurol. 2006, 13:1340-1345.
    • (2006) Eur. J. Neurol. , vol.13 , pp. 1340-1345
    • Bilic, E.1    Bilic, E.2    Rudan, I.3    Kusec, V.4    Zurak, N.5    Delimar, D.6    Zagar, M.7
  • 17
    • 71549118827 scopus 로고    scopus 로고
    • Applying proteomics to the diagnosis and treatment of ALS and related diseases
    • Bowser R., Lacomis D. Applying proteomics to the diagnosis and treatment of ALS and related diseases. Muscle Nerve 2009, 40:753-762.
    • (2009) Muscle Nerve , vol.40 , pp. 753-762
    • Bowser, R.1    Lacomis, D.2
  • 18
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H., Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 1991, 82:239-259.
    • (1991) Acta Neuropathol. , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 19
    • 2542567240 scopus 로고    scopus 로고
    • Alzheimer's disease: intraneuronal alterations precede insoluble amyloid-beta formation
    • (discussion 743-746)
    • Braak H., Del Tredici K. Alzheimer's disease: intraneuronal alterations precede insoluble amyloid-beta formation. Neurobiol. Aging 2004, 25:713-718. (discussion 743-746).
    • (2004) Neurobiol. Aging , vol.25 , pp. 713-718
    • Braak, H.1    Del Tredici, K.2
  • 20
    • 79451471618 scopus 로고    scopus 로고
    • The pathological process underlying Alzheimer's disease in individuals under thirty
    • Braak H., Del Tredici K. The pathological process underlying Alzheimer's disease in individuals under thirty. Acta Neuropathol. 2011, 121:171-181.
    • (2011) Acta Neuropathol. , vol.121 , pp. 171-181
    • Braak, H.1    Del Tredici, K.2
  • 22
    • 33749150163 scopus 로고    scopus 로고
    • Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
    • Braak H., Alafuzoff I., Arzberger T., Kretzschmar H., Del Tredici K. Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol. 2006, 112:389-404.
    • (2006) Acta Neuropathol. , vol.112 , pp. 389-404
    • Braak, H.1    Alafuzoff, I.2    Arzberger, T.3    Kretzschmar, H.4    Del Tredici, K.5
  • 23
    • 77953870938 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis: dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord
    • Braak H., Ludolph A., Thal D.R., Del Tredici K. Amyotrophic lateral sclerosis: dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord. Acta Neuropathol. 2010, 120:67-74.
    • (2010) Acta Neuropathol. , vol.120 , pp. 67-74
    • Braak, H.1    Ludolph, A.2    Thal, D.R.3    Del Tredici, K.4
  • 28
    • 0037465770 scopus 로고    scopus 로고
    • Staging disease severity in pathologically confirmed cases of frontotemporal dementia
    • Broe M., Hodges J.R., Schofield E., Shepherd C.E., Kril J.J., Halliday G.M. Staging disease severity in pathologically confirmed cases of frontotemporal dementia. Neurology 2003, 60:1005-1011.
    • (2003) Neurology , vol.60 , pp. 1005-1011
    • Broe, M.1    Hodges, J.R.2    Schofield, E.3    Shepherd, C.E.4    Kril, J.J.5    Halliday, G.M.6
  • 29
    • 0028142392 scopus 로고
    • El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial "Clinical limits of amyotrophic lateral sclerosis" workshop contributors
    • Brooks B.R. El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial "Clinical limits of amyotrophic lateral sclerosis" workshop contributors. J. Neurol. Sci. 1994, 124(Suppl.):96-107.
    • (1994) J. Neurol. Sci. , vol.124 , Issue.SUPPL. , pp. 96-107
    • Brooks, B.R.1
  • 32
    • 0029017278 scopus 로고
    • Motor neuron disease (amyotrophic lateral sclerosis) arising from longstanding primary lateral sclerosis
    • Bruyn R.P., Koelman J.H., Troost D., de Jong J.M. Motor neuron disease (amyotrophic lateral sclerosis) arising from longstanding primary lateral sclerosis. J. Neurol. Neurosurg. Psychiatry 1995, 58:742-744.
    • (1995) J. Neurol. Neurosurg. Psychiatry , vol.58 , pp. 742-744
    • Bruyn, R.P.1    Koelman, J.H.2    Troost, D.3    de Jong, J.M.4
  • 33
    • 38449102667 scopus 로고    scopus 로고
    • Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease
    • Buratti E., Baralle F.E. Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease. Front. Biosci. 2008, 13:867-878.
    • (2008) Front. Biosci. , vol.13 , pp. 867-878
    • Buratti, E.1    Baralle, F.E.2
  • 34
    • 80052924149 scopus 로고    scopus 로고
    • Motor Neuron dysfunction in frontotemporal dementia
    • Burrell J.R., Kiernan M.C., Vucic S., Hodges J.R. Motor Neuron dysfunction in frontotemporal dementia. Brain 2011, 134:2582-2594.
    • (2011) Brain , vol.134 , pp. 2582-2594
    • Burrell, J.R.1    Kiernan, M.C.2    Vucic, S.3    Hodges, J.R.4
  • 40
    • 79953879390 scopus 로고    scopus 로고
    • Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration
    • Chen-Plotkin A.S., Martinez-Lage M., Sleiman P.M.A., Hu W., Greene R., et al. Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration. Arch. Neurol. 2011, 68:488-497.
    • (2011) Arch. Neurol. , vol.68 , pp. 488-497
    • Chen-Plotkin, A.S.1    Martinez-Lage, M.2    Sleiman, P.M.A.3    Hu, W.4    Greene, R.5
  • 44
    • 0027296350 scopus 로고
    • Amyotrophic lateral sclerosis: lower motor neuron disease spreading to upper motor neurons
    • Chou S.M., Norris F.H. Amyotrophic lateral sclerosis: lower motor neuron disease spreading to upper motor neurons. Muscle Nerve 1993, 16:864-869.
    • (1993) Muscle Nerve , vol.16 , pp. 864-869
    • Chou, S.M.1    Norris, F.H.2
  • 45
    • 77953068390 scopus 로고    scopus 로고
    • Synergistic Interactions between abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline
    • Clinton L.K., Blurton-Jones M., Myczek K., Trojanowski J.Q., LaFerla F.M. Synergistic Interactions between abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline. J. Neurosci. 2010, 30:7281-7289.
    • (2010) J. Neurosci. , vol.30 , pp. 7281-7289
    • Clinton, L.K.1    Blurton-Jones, M.2    Myczek, K.3    Trojanowski, J.Q.4    LaFerla, F.M.5
  • 46
    • 80755153025 scopus 로고    scopus 로고
    • TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies
    • Cohen T.J., Lee V.M.Y., Trojanowski J.Q. TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies. Trends Mol. Med. 2011.
    • (2011) Trends Mol. Med.
    • Cohen, T.J.1    Lee, V.M.Y.2    Trojanowski, J.Q.3
  • 57
    • 34447094657 scopus 로고    scopus 로고
    • TDP-43 in differential diagnosis of motor neuron disorders
    • Dickson D.W., Josephs K.A., Amador-Ortiz C. TDP-43 in differential diagnosis of motor neuron disorders. Acta Neuropathol. 2007, 114:71-79.
    • (2007) Acta Neuropathol. , vol.114 , pp. 71-79
    • Dickson, D.W.1    Josephs, K.A.2    Amador-Ortiz, C.3
  • 66
    • 77949910265 scopus 로고    scopus 로고
    • Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration
    • Gendron T.F., Josephs K.A., Petrucelli L. Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration. Neuropathol. Appl. Neurobiol. 2010, 36:97-112.
    • (2010) Neuropathol. Appl. Neurobiol. , vol.36 , pp. 97-112
    • Gendron, T.F.1    Josephs, K.A.2    Petrucelli, L.3
  • 69
    • 68349125007 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: the TDP-43 diseases
    • Geser F., Martinez-Lage M., Kwong L.K., Lee V.M.-Y., Trojanowski J.Q. Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: the TDP-43 diseases. J. Neurol. 2009, 256:1205-1214.
    • (2009) J. Neurol. , vol.256 , pp. 1205-1214
    • Geser, F.1    Martinez-Lage, M.2    Kwong, L.K.3    Lee, V.M.-Y.4    Trojanowski, J.Q.5
  • 71
    • 77949897022 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: a spectrum of TDP-43 proteinopathies
    • Geser F., Lee V.M.-Y., Trojanowski J.Q. Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: a spectrum of TDP-43 proteinopathies. Neuropathology 2010, 30:103-112.
    • (2010) Neuropathology , vol.30 , pp. 103-112
    • Geser, F.1    Lee, V.M.-Y.2    Trojanowski, J.Q.3
  • 79
    • 82755191185 scopus 로고    scopus 로고
    • Brainstem: neglected locus in neurodegenerative diseases
    • Grinberg L.T., Rueb U., Heinsen H. Brainstem: neglected locus in neurodegenerative diseases. Front. Neurol. 2011, 2:42.
    • (2011) Front. Neurol. , vol.2 , pp. 42
    • Grinberg, L.T.1    Rueb, U.2    Heinsen, H.3
  • 93
    • 0027480196 scopus 로고
    • Clinicopathological features of primary lateral sclerosis are different from amyotrophic lateral sclerosis
    • Hudson A.J., Kiernan J.A., Munoz D.G., Pringle C.E., Brown W.F., Ebers G.C. Clinicopathological features of primary lateral sclerosis are different from amyotrophic lateral sclerosis. Brain Res. Bull. 1993, 30:359-364.
    • (1993) Brain Res. Bull. , vol.30 , pp. 359-364
    • Hudson, A.J.1    Kiernan, J.A.2    Munoz, D.G.3    Pringle, C.E.4    Brown, W.F.5    Ebers, G.C.6
  • 97
    • 78649524570 scopus 로고    scopus 로고
    • Is lesion of Exner's area linked to progressive agraphia in amyotrophic lateral sclerosis with dementia? An autopsy case report
    • Ishihara K., Ichikawa H., Suzuki Y., Shiota J., Nakano I., Kawamura M. Is lesion of Exner's area linked to progressive agraphia in amyotrophic lateral sclerosis with dementia? An autopsy case report. Behav. Neurol. 2010, 23:153-158.
    • (2010) Behav. Neurol. , vol.23 , pp. 153-158
    • Ishihara, K.1    Ichikawa, H.2    Suzuki, Y.3    Shiota, J.4    Nakano, I.5    Kawamura, M.6
  • 98
    • 26444610170 scopus 로고    scopus 로고
    • Grading of neuropathology in multiple system atrophy: proposal for a novel scale
    • Jellinger K.A., Seppi K., Wenning G.K. Grading of neuropathology in multiple system atrophy: proposal for a novel scale. Mov. Disord. 2005, 20(Suppl. 12):S29-S36.
    • (2005) Mov. Disord. , vol.20 , Issue.SUPPL. 12
    • Jellinger, K.A.1    Seppi, K.2    Wenning, G.K.3
  • 99
    • 35848938274 scopus 로고    scopus 로고
    • Frontotemporal lobar degeneration with upper motor neuron disease/primary lateral sclerosis
    • Josephs K.A., Dickson D.W. Frontotemporal lobar degeneration with upper motor neuron disease/primary lateral sclerosis. Neurology 2007, 69:1800-1801.
    • (2007) Neurology , vol.69 , pp. 1800-1801
    • Josephs, K.A.1    Dickson, D.W.2
  • 103
    • 70349308579 scopus 로고    scopus 로고
    • Regional distribution of TDP-43 inclusions in Alzheimer disease (AD) brains: their relation to AD common pathology
    • Kadokura A., Yamazaki T., Lemere C.A., Takatama M., Okamoto K. Regional distribution of TDP-43 inclusions in Alzheimer disease (AD) brains: their relation to AD common pathology. Neuropathology 2009, 29:566-573.
    • (2009) Neuropathology , vol.29 , pp. 566-573
    • Kadokura, A.1    Yamazaki, T.2    Lemere, C.A.3    Takatama, M.4    Okamoto, K.5
  • 107
    • 33749860079 scopus 로고    scopus 로고
    • Plasma and cerebrospinal fluid-based protein biomarkers for motor neuron disease
    • Kolarcik C., Bowser R. Plasma and cerebrospinal fluid-based protein biomarkers for motor neuron disease. Mol. Diagn. Ther. 2006, 10:281-292.
    • (2006) Mol. Diagn. Ther. , vol.10 , pp. 281-292
    • Kolarcik, C.1    Bowser, R.2
  • 109
    • 77953023964 scopus 로고    scopus 로고
    • Protein coding of neurodegenerative dementias: the neuropathological basis of biomarker diagnostics
    • Kovacs G.G., Botond G., Budka H. Protein coding of neurodegenerative dementias: the neuropathological basis of biomarker diagnostics. Acta Neuropathol. 2010, 119:389-408.
    • (2010) Acta Neuropathol. , vol.119 , pp. 389-408
    • Kovacs, G.G.1    Botond, G.2    Budka, H.3
  • 110
    • 80855143713 scopus 로고    scopus 로고
    • Pathological staging of frontotemporal lobar degeneration
    • Kril J.J., Halliday G.M. Pathological staging of frontotemporal lobar degeneration. J. Mol. Neurosci. 2011.
    • (2011) J. Mol. Neurosci.
    • Kril, J.J.1    Halliday, G.M.2
  • 115
    • 62149141328 scopus 로고    scopus 로고
    • Rethinking ALS: the FUS about TDP-43
    • Lagier-Tourenne C., Cleveland D.W. Rethinking ALS: the FUS about TDP-43. Cell 2009, 136:1001-1004.
    • (2009) Cell , vol.136 , pp. 1001-1004
    • Lagier-Tourenne, C.1    Cleveland, D.W.2
  • 117
    • 39749083266 scopus 로고    scopus 로고
    • TDP-43 immunoreactivity in anoxic, ischemic and neoplastic lesions of the central nervous system
    • Lee E.B., Lee V.M.-Y., Trojanowski J.Q., Neumann M. TDP-43 immunoreactivity in anoxic, ischemic and neoplastic lesions of the central nervous system. Acta Neuropathol. 2008, 115:305-311.
    • (2008) Acta Neuropathol. , vol.115 , pp. 305-311
    • Lee, E.B.1    Lee, V.M.-Y.2    Trojanowski, J.Q.3    Neumann, M.4
  • 120
    • 0025729489 scopus 로고
    • Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity
    • Leigh P.N., Whitwell H., Garofalo O., Buller J., Swash M., Martin J.E., Gallo J.M., Weller R.O., Anderton B.H. Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity. Brain 1991, 114(Pt 2):775-788.
    • (1991) Brain , vol.114 , Issue.PART 2 , pp. 775-788
    • Leigh, P.N.1    Whitwell, H.2    Garofalo, O.3    Buller, J.4    Swash, M.5    Martin, J.E.6    Gallo, J.M.7    Weller, R.O.8    Anderton, B.H.9
  • 122
    • 70449367272 scopus 로고    scopus 로고
    • Transactivation response DNA-binding protein 43 microvasculopathy in frontotemporal degeneration and familial Lewy body disease
    • Lin W.-L., Castanedes-Casey M., Dickson D.W. Transactivation response DNA-binding protein 43 microvasculopathy in frontotemporal degeneration and familial Lewy body disease. J. Neuropathol. Exp. Neurol. 2009, 68:1167-1176.
    • (2009) J. Neuropathol. Exp. Neurol. , vol.68 , pp. 1167-1176
    • Lin, W.-L.1    Castanedes-Casey, M.2    Dickson, D.W.3
  • 123
    • 56749093062 scopus 로고    scopus 로고
    • The role of transactive response DNA-binding protein-43 in amyotrophic lateral sclerosis and frontotemporal dementia
    • Mackenzie I.R.A., Rademakers R. The role of transactive response DNA-binding protein-43 in amyotrophic lateral sclerosis and frontotemporal dementia. Curr. Opin. Neurol. 2008, 21:693-700.
    • (2008) Curr. Opin. Neurol. , vol.21 , pp. 693-700
    • Mackenzie, I.R.A.1    Rademakers, R.2
  • 126
    • 77956850818 scopus 로고    scopus 로고
    • TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
    • Mackenzie I.R., Rademakers R., Neumann M. TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia. Lancet Neurol. 2010, 9:995-1007.
    • (2010) Lancet Neurol. , vol.9 , pp. 995-1007
    • Mackenzie, I.R.1    Rademakers, R.2    Neumann, M.3
  • 132
    • 56749098112 scopus 로고    scopus 로고
    • Enduring involvement of tau, beta-amyloid, alpha-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam (ALS/PDC)
    • Miklossy J., Steele J.C., Yu S., McCall S., Sandberg G., McGeer E.G., McGeer P.L. Enduring involvement of tau, beta-amyloid, alpha-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam (ALS/PDC). Acta Neuropathol. 2008, 116:625-637.
    • (2008) Acta Neuropathol. , vol.116 , pp. 625-637
    • Miklossy, J.1    Steele, J.C.2    Yu, S.3    McCall, S.4    Sandberg, G.5    McGeer, E.G.6    McGeer, P.L.7
  • 133
    • 34250209501 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis
    • Mitchell J.D., Borasio G.D. Amyotrophic lateral sclerosis. Lancet 2007, 369:2031-2041.
    • (2007) Lancet , vol.369 , pp. 2031-2041
    • Mitchell, J.D.1    Borasio, G.D.2
  • 135
    • 47949099336 scopus 로고    scopus 로고
    • Maturation process of TDP-43-positive neuronal cytoplasmic inclusions in amyotrophic lateral sclerosis with and without dementia
    • Mori F., Tanji K., Zhang H.-X., Nishihira Y., Tan C.-F., Takahashi H., Wakabayashi K. Maturation process of TDP-43-positive neuronal cytoplasmic inclusions in amyotrophic lateral sclerosis with and without dementia. Acta Neuropathol. 2008, 116:193-203.
    • (2008) Acta Neuropathol. , vol.116 , pp. 193-203
    • Mori, F.1    Tanji, K.2    Zhang, H.-X.3    Nishihira, Y.4    Tan, C.-F.5    Takahashi, H.6    Wakabayashi, K.7
  • 138
    • 59649086176 scopus 로고    scopus 로고
    • Molecular neuropathology of TDP-43 proteinopathies
    • Neumann M. Molecular neuropathology of TDP-43 proteinopathies. Int. J. Mol. Sci. 2009, 10:232-246.
    • (2009) Int. J. Mol. Sci. , vol.10 , pp. 232-246
    • Neumann, M.1
  • 144
    • 47949096734 scopus 로고    scopus 로고
    • Sporadic amyotrophic lateral sclerosis: two pathological patterns shown by analysis of distribution of TDP-43-immunoreactive neuronal and glial cytoplasmic inclusions
    • Nishihira Y., Tan C.-F., Onodera O., Toyoshima Y., Yamada M., Morita T., Nishizawa M., Kakita A., Takahashi H. Sporadic amyotrophic lateral sclerosis: two pathological patterns shown by analysis of distribution of TDP-43-immunoreactive neuronal and glial cytoplasmic inclusions. Acta Neuropathol. 2008, 116:169-182.
    • (2008) Acta Neuropathol. , vol.116 , pp. 169-182
    • Nishihira, Y.1    Tan, C.-F.2    Onodera, O.3    Toyoshima, Y.4    Yamada, M.5    Morita, T.6    Nishizawa, M.7    Kakita, A.8    Takahashi, H.9
  • 146
    • 65149090786 scopus 로고    scopus 로고
    • Sporadic amyotrophic lateral sclerosis: widespread multisystem degeneration with TDP-43 pathology in a patient after long-term survival on a respirator
    • Nishihira Y., Tan C.-F., Toyoshima Y., Yonemochi Y., Kondo H., Nakajima T., Takahashi H. Sporadic amyotrophic lateral sclerosis: widespread multisystem degeneration with TDP-43 pathology in a patient after long-term survival on a respirator. Neuropathology 2009, 29:689-696.
    • (2009) Neuropathology , vol.29 , pp. 689-696
    • Nishihira, Y.1    Tan, C.-F.2    Toyoshima, Y.3    Yonemochi, Y.4    Kondo, H.5    Nakajima, T.6    Takahashi, H.7
  • 149
    • 79957537225 scopus 로고    scopus 로고
    • Semantic dementia with lower motor neuron disease showing FTLD-TDP type 3 pathology (sensu Mackenzie)
    • östberg P., Bogdanović N. Semantic dementia with lower motor neuron disease showing FTLD-TDP type 3 pathology (sensu Mackenzie). Neuropathology 2011, 31:271-279.
    • (2011) Neuropathology , vol.31 , pp. 271-279
    • östberg, P.1    Bogdanović, N.2
  • 151
    • 61849158637 scopus 로고    scopus 로고
    • TDP-43 neuropathology is similar in sporadic amyotrophic lateral sclerosis with or without TDP-43 mutations
    • Pamphlett R., Luquin N., McLean C., Jew S.K., Adams L. TDP-43 neuropathology is similar in sporadic amyotrophic lateral sclerosis with or without TDP-43 mutations. Neuropathol. Appl. Neurobiol. 2009, 35:222-225.
    • (2009) Neuropathol. Appl. Neurobiol. , vol.35 , pp. 222-225
    • Pamphlett, R.1    Luquin, N.2    McLean, C.3    Jew, S.K.4    Adams, L.5
  • 153
    • 77649252528 scopus 로고    scopus 로고
    • Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis
    • Pesiridis G.S., Lee V.M.-Y., Trojanowski J.Q. Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis. Hum. Mol. Genet. 2009, 18:R156-R162.
    • (2009) Hum. Mol. Genet. , vol.18
    • Pesiridis, G.S.1    Lee, V.M.-Y.2    Trojanowski, J.Q.3
  • 154
    • 67650480216 scopus 로고    scopus 로고
    • Biomarkers in amyotrophic lateral sclerosis: facts and future horizons
    • Pradat P.-F., Dib M. Biomarkers in amyotrophic lateral sclerosis: facts and future horizons. Mol. Diagn. Ther. 2009, 13:115-125.
    • (2009) Mol. Diagn. Ther. , vol.13 , pp. 115-125
    • Pradat, P.-F.1    Dib, M.2
  • 155
    • 0026682621 scopus 로고
    • Primary lateral sclerosis. Clinical features, neuropathology and diagnostic criteria
    • Pringle C.E., Hudson A.J., Munoz D.G., Kiernan J.A., Brown W.F., Ebers G.C. Primary lateral sclerosis. Clinical features, neuropathology and diagnostic criteria. Brain 1992, 115(Pt 2):495-520.
    • (1992) Brain , vol.115 , Issue.PART 2 , pp. 495-520
    • Pringle, C.E.1    Hudson, A.J.2    Munoz, D.G.3    Kiernan, J.A.4    Brown, W.F.5    Ebers, G.C.6
  • 158
    • 70349581626 scopus 로고    scopus 로고
    • ALS motor phenotype heterogeneity, focality, and spread: deconstructing motor neuron degeneration
    • Ravits J.M., La Spada A.R. ALS motor phenotype heterogeneity, focality, and spread: deconstructing motor neuron degeneration. Neurology 2009, 73:805-811.
    • (2009) Neurology , vol.73 , pp. 805-811
    • Ravits, J.M.1    La Spada, A.R.2
  • 160
    • 47949123961 scopus 로고    scopus 로고
    • TDP-43-negative FTLD-U is a significant new clinico-pathological subtype of FTLD
    • Roeber S., Mackenzie I.R.A., Kretzschmar H.A., Neumann M. TDP-43-negative FTLD-U is a significant new clinico-pathological subtype of FTLD. Acta Neuropathol. 2008, 116:147-157.
    • (2008) Acta Neuropathol. , vol.116 , pp. 147-157
    • Roeber, S.1    Mackenzie, I.R.A.2    Kretzschmar, H.A.3    Neumann, M.4
  • 170
    • 33846076379 scopus 로고    scopus 로고
    • Pathological heterogeneity of frontotemporal lobar degeneration with ubiquitin-positive inclusions delineated by ubiquitin immunohistochemistry and novel monoclonal antibodies
    • Sampathu D.M., Neumann M., Kwong L.K., Chou T.T., Micsenyi M., Truax A., Bruce J., Grossman M., Trojanowski J.Q., Lee V.M.-Y. Pathological heterogeneity of frontotemporal lobar degeneration with ubiquitin-positive inclusions delineated by ubiquitin immunohistochemistry and novel monoclonal antibodies. Am. J. Pathol. 2006, 169:1343-1352.
    • (2006) Am. J. Pathol. , vol.169 , pp. 1343-1352
    • Sampathu, D.M.1    Neumann, M.2    Kwong, L.K.3    Chou, T.T.4    Micsenyi, M.5    Truax, A.6    Bruce, J.7    Grossman, M.8    Trojanowski, J.Q.9    Lee, V.M.-Y.10
  • 171
    • 37349034999 scopus 로고    scopus 로고
    • Evidence that TDP-43 is not the major ubiquitinated target within the pathological inclusions of amyotrophic lateral sclerosis
    • Sanelli T., Xiao S., Horne P., Bilbao J., Zinman L., Robertson J. Evidence that TDP-43 is not the major ubiquitinated target within the pathological inclusions of amyotrophic lateral sclerosis. J. Neuropathol. Exp. Neurol. 2007, 66:1147-1153.
    • (2007) J. Neuropathol. Exp. Neurol. , vol.66 , pp. 1147-1153
    • Sanelli, T.1    Xiao, S.2    Horne, P.3    Bilbao, J.4    Zinman, L.5    Robertson, J.6
  • 173
    • 58149398638 scopus 로고    scopus 로고
    • Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease
    • Schwab C., Arai T., Hasegawa M., Yu S., McGeer P.L. Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease. J. Neuropathol. Exp. Neurol. 2008, 67:1159-1165.
    • (2008) J. Neuropathol. Exp. Neurol. , vol.67 , pp. 1159-1165
    • Schwab, C.1    Arai, T.2    Hasegawa, M.3    Yu, S.4    McGeer, P.L.5
  • 177
    • 33645728523 scopus 로고    scopus 로고
    • Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications
    • Skovronsky D.M., Lee V.M.-Y., Trojanowski J.Q. Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications. Annu. Rev. Pathol. 2006, 1:151-170.
    • (2006) Annu. Rev. Pathol. , vol.1 , pp. 151-170
    • Skovronsky, D.M.1    Lee, V.M.-Y.2    Trojanowski, J.Q.3
  • 182
    • 54049140363 scopus 로고    scopus 로고
    • The syndromes of frontotemporal dysfunction in amyotrophic lateral sclerosis
    • Strong M.J. The syndromes of frontotemporal dysfunction in amyotrophic lateral sclerosis. Amyotroph. Lateral Scler. 2008, 9:323-338.
    • (2008) Amyotroph. Lateral Scler. , vol.9 , pp. 323-338
    • Strong, M.J.1
  • 186
    • 0038142688 scopus 로고    scopus 로고
    • Primary lateral sclerosis: a rare upper-motor-predominant form of amyotrophic lateral sclerosis often accompanied by frontotemporal lobar degeneration with ubiquitinated neuronal inclusions? Report of an autopsy case and a review of the literature
    • Tan C.-F., Kakita A., Piao Y.-S., Kikugawa K., Endo K., Tanaka M., Okamoto K., Takahashi H. Primary lateral sclerosis: a rare upper-motor-predominant form of amyotrophic lateral sclerosis often accompanied by frontotemporal lobar degeneration with ubiquitinated neuronal inclusions? Report of an autopsy case and a review of the literature. Acta Neuropathol. 2003, 105:615-620.
    • (2003) Acta Neuropathol. , vol.105 , pp. 615-620
    • Tan, C.-F.1    Kakita, A.2    Piao, Y.-S.3    Kikugawa, K.4    Endo, K.5    Tanaka, M.6    Okamoto, K.7    Takahashi, H.8
  • 188
    • 33846973022 scopus 로고    scopus 로고
    • Differentiation between primary lateral sclerosis and amyotrophic lateral sclerosis: examination of symptoms and signs at disease onset and during follow-up
    • Tartaglia M.C., Rowe A., Findlater K., Orange J.B., Grace G., Strong M.J. Differentiation between primary lateral sclerosis and amyotrophic lateral sclerosis: examination of symptoms and signs at disease onset and during follow-up. Arch. Neurol. 2007, 64:232-236.
    • (2007) Arch. Neurol. , vol.64 , pp. 232-236
    • Tartaglia, M.C.1    Rowe, A.2    Findlater, K.3    Orange, J.B.4    Grace, G.5    Strong, M.J.6
  • 190
    • 0037172826 scopus 로고    scopus 로고
    • Phases of A beta-deposition in the human brain and its relevance for the development of AD
    • Thal D.R., Rüb U., Orantes M., Braak H. Phases of A beta-deposition in the human brain and its relevance for the development of AD. Neurology 2002, 58:1791-1800.
    • (2002) Neurology , vol.58 , pp. 1791-1800
    • Thal, D.R.1    Rüb, U.2    Orantes, M.3    Braak, H.4
  • 192
    • 4644247990 scopus 로고    scopus 로고
    • Sporadic amyotrophic lateral sclerosis of long duration mimicking spinal progressive muscular atrophy exists: additional autopsy case with a clinical course of 19 years
    • Tsuchiya K., Sano M., Shiotsu H., Akiyama H., Watabiki S., Taki K., Kondo H., Nakano I., Ikeda K. Sporadic amyotrophic lateral sclerosis of long duration mimicking spinal progressive muscular atrophy exists: additional autopsy case with a clinical course of 19 years. Neuropathology 2004, 24:228-235.
    • (2004) Neuropathology , vol.24 , pp. 228-235
    • Tsuchiya, K.1    Sano, M.2    Shiotsu, H.3    Akiyama, H.4    Watabiki, S.5    Taki, K.6    Kondo, H.7    Nakano, I.8    Ikeda, K.9
  • 197
    • 77649136250 scopus 로고    scopus 로고
    • Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions
    • Van Deerlin V.M., Sleiman P.M.A., Martinez-Lage M., Chen-Plotkin A., Wang L.-S., et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat. Genet. 2010, 42:234-239.
    • (2010) Nat. Genet. , vol.42 , pp. 234-239
    • Van Deerlin, V.M.1    Sleiman, P.M.A.2    Martinez-Lage, M.3    Chen-Plotkin, A.4    Wang, L.-S.5
  • 199
    • 70349592269 scopus 로고    scopus 로고
    • Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis
    • Van Es M.A., Veldink J.H., Saris C.G.J., Blauw H.M., van Vught P.W.J., et al. Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat. Genet. 2009, 41:1083-1087.
    • (2009) Nat. Genet. , vol.41 , pp. 1083-1087
    • Van Es, M.A.1    Veldink, J.H.2    Saris, C.G.J.3    Blauw, H.M.4    van Vught, P.W.J.5
  • 201
    • 0033600228 scopus 로고    scopus 로고
    • A stop-codon mutation in the BRI gene associated with familial British dementia
    • Vidal R., Frangione B., Rostagno A., Mead S., Révész T., Plant G., Ghiso J. A stop-codon mutation in the BRI gene associated with familial British dementia. Nature 1999, 399:776-781.
    • (1999) Nature , vol.399 , pp. 776-781
    • Vidal, R.1    Frangione, B.2    Rostagno, A.3    Mead, S.4    Révész, T.5    Plant, G.6    Ghiso, J.7
  • 203
    • 54249100481 scopus 로고    scopus 로고
    • TDP-43: an emerging new player in neurodegenerative diseases
    • Wang I.-F., Wu L.-S., Shen C.-K.J. TDP-43: an emerging new player in neurodegenerative diseases. Trends Mol. Med. 2008, 14:479-485.
    • (2008) Trends Mol. Med. , vol.14 , pp. 479-485
    • Wang, I.-F.1    Wu, L.-S.2    Shen, C.-K.J.3
  • 206
    • 0036208772 scopus 로고    scopus 로고
    • A novel grading scale for striatonigral degeneration (multiple system atrophy)
    • Wenning G.K., Seppi K., Tison F., Jellinger K. A novel grading scale for striatonigral degeneration (multiple system atrophy). J. Neural. Transm. 2002, 109:307-320.
    • (2002) J. Neural. Transm. , vol.109 , pp. 307-320
    • Wenning, G.K.1    Seppi, K.2    Tison, F.3    Jellinger, K.4
  • 212
    • 44749091997 scopus 로고    scopus 로고
    • Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation
    • Winton M.J., Igaz L.M., Wong M.M., Kwong L.K., Trojanowski J.Q., Lee V.M.-Y. Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation. J. Biol. Chem. 2008, 283:13302-13309.
    • (2008) J. Biol. Chem. , vol.283 , pp. 13302-13309
    • Winton, M.J.1    Igaz, L.M.2    Wong, M.M.3    Kwong, L.K.4    Trojanowski, J.Q.5    Lee, V.M.-Y.6
  • 213
    • 36949022900 scopus 로고    scopus 로고
    • CAG repeat disorder models and human neuropathology: similarities and differences
    • Yamada M., Sato T., Tsuji S., Takahashi H. CAG repeat disorder models and human neuropathology: similarities and differences. Acta Neuropathol. 2008, 115:71-86.
    • (2008) Acta Neuropathol. , vol.115 , pp. 71-86
    • Yamada, M.1    Sato, T.2    Tsuji, S.3    Takahashi, H.4
  • 220
    • 36248939088 scopus 로고    scopus 로고
    • Cerebrospinal fluid neurofilament light levels in amyotrophic lateral sclerosis: impact of SOD1 genotype
    • Zetterberg H., Jacobsson J., Rosengren L., Blennow K., Andersen P.M. Cerebrospinal fluid neurofilament light levels in amyotrophic lateral sclerosis: impact of SOD1 genotype. Eur. J. Neurol. 2007, 14:1329-1333.
    • (2007) Eur. J. Neurol. , vol.14 , pp. 1329-1333
    • Zetterberg, H.1    Jacobsson, J.2    Rosengren, L.3    Blennow, K.4    Andersen, P.M.5
  • 221
    • 36949008994 scopus 로고    scopus 로고
    • TDP-43-immunoreactive neuronal and glial inclusions in the neostriatum in amyotrophic lateral sclerosis with and without dementia
    • Zhang H., Tan C.-F., Mori F., Tanji K., Kakita A., Takahashi H., Wakabayashi K. TDP-43-immunoreactive neuronal and glial inclusions in the neostriatum in amyotrophic lateral sclerosis with and without dementia. Acta Neuropathol. 2008, 115:115-122.
    • (2008) Acta Neuropathol. , vol.115 , pp. 115-122
    • Zhang, H.1    Tan, C.-F.2    Mori, F.3    Tanji, K.4    Kakita, A.5    Takahashi, H.6    Wakabayashi, K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.