Als motor phenotype heterogeneity, focality, and spread: Deconstructing motor neuron degenerationsymbol

Neurology

Volumn 73, Issue 10, 2009, Pages 805-

  Ravits, John M ^a   La Spada, Albert R ^b  

^a BENAROYA RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL; GENETICS; HUMAN; MOTONEURON; NERVE CONDUCTION; NERVE DEGENERATION; PATHOPHYSIOLOGY; PHENOTYPE; PHYSIOLOGY; REVIEW;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; HUMANS; MOTOR NEURONS; NERVE DEGENERATION; NEURAL CONDUCTION; PHENOTYPE;

EID: 70349581626     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3181b6bbbd     Document Type: Article

References (52)

1. JM Charcot Sclérose latérale amyotrophique Oeuvres Complètes Vol 2 1897 Bureaux du Progrès Mèdical Paris 249 266 (In English: Amyotrophic lateral sclerosis: symptomatology. In: Sigerson G, trans. Lectures on Diseases of the Nervous System. London: New Sydenham Society; 1881: 192–204) (cited from reference 3 ).
2. WR Gowers Manual of Diseases of the Nervous System 1886–1888 Churchill London (reprinted special edition: Birmingham, AL: Classics of Medicine Library; 1981).
3. JA Kiernan AJ Hudson Changes in sizes of cortical and lower motor neurons in amyotrophic lateral sclerosis Brain 114 1991 843 853
4. K Nihei AC McKee NW Kowall Patterns of neuronal degeneration in the motor cortex of amyotrophic lateral sclerosis Acta Neuropathol 86 1993 55 64
5. R Pamphlett J Kril TM Hng Motor neuron disease: a primary disorder of corticomotor neurons? Muscle Nerve 18 1995 314 318
6. S Attarian JP Vedel J Pouget A Schmied Progression of cortical and spinal dysfunctions over time in amyotrophic lateral sclerosis Muscle Nerve 37 2008 364 375
7. Y Mochizuki T Mizutani T Takasu Amyotrophic lateral sclerosis with marked neurological asymmetry: clinicopathological study Acta Neuropathol 90 1995 44 50
8. A Eisen S Kim B Pant Amyotrophic lateral sclerosis (ALS): a phylogenetic disease of the corticomotorneuron? Muscle Nerve 15 1992 219 224
9. A Eisen M Weber The motor cortex and amyotrophic lateral sclerosis Muscle Nerve 24 2001 564 573
10. M Swash Amyotrophic lateral sclerosis: a phylogenetic disease of the corticomotor neuron? Comments on the hypothesis Muscle Nerve 15 1992 226 228
11. G Karpati J Kimura Amyotrophic lateral sclerosis: a critique of a hypothesis Muscle Nerve 15 1992 224 226
12. SM Chou FH Norris Amyotrophic lateral sclerosis: lower motor neuron disease spreading to upper motor neurons Muscle Nerve 9 1993 864 869
13. S Guettier-Sigrist B Hugel G Coupin Possible pathogenic role of muscle cell dysfunction in motor neuron death in spinal muscular atrophy Muscle Nerve 25 2002 700 708
14. LR Fischer DG Culver P Tennant Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man Exp Neurol 185 2004 232 240
15. M Jokelainen Amyotrophic lateral sclerosis in Finland II: clinical characteristics Acta Neurol Scand 56 1977 194 204
16. DW Mulder Clinical limits of amyotrophic lateral sclerosis LP Rowland Human Motor Diseases 1982 Raven Press 15 22
17. SS Gubbay E Kahana N Zilber Amyotrophic lateral sclerosis: a study of its presentation and prognosis J Neurol 232 1985 295 300
18. JT Caroscio MN Mulvihill R Sterling Amyotrophic lateral sclerosis: its natural history Neurol Clin 5 1987 1 8
19. M Swash Vulnerability of lower brachial myotomes in motor neurone disease: a clinical and single fibre EMG study J Neurol Sci 47 1980 59 68
20. M Swash M Leader A Brown KW Swettenham Focal loss of anterior horn cells in the cervical cord in motor neuron disease Brain 109 1986 939 952
21. BR Brooks The role of axonal transport in neurodegenerative disease spread: a meta-analysis of experimental and clinical poliomyelitis compares with amyotrophic lateral sclerosis Can J Neurol Sci 18 1991 435 438
22. TL Munsat PL Andres L Finison The natural history of motor neuron loss in amyotrophic lateral sclerosis Neurology 38 1988 409 413
23. C Armon Acquired nucleic acid changes may trigger sporadic amyotrophic lateral sclerosis Muscle Nerve 32 2005 373 377
24. J Ravits P Paul C Jorg Focality of upper and lower motor neuron degeneration at the clinical onset of ALS Neurology 68 2007 1571 1575
25. J Ravits P Laurie Y Fan DH Moore Implications of ALS focality: rostral-caudal distribution of lower motor neuron loss postmortem Neurology 68 2007 1576 1582
26. WF Brown TJ Doherty M Chan Human motor units in health and disease Muscle Nerve Suppl 9 2000 S7 S18
27. R Porter R Lemon Corticospinal Function and Voluntary Movement 1993 Clarendon Press Oxford, UK
28. G Luppino G Rizzolatti The organization of the frontal motor cortex News Physiol Si 15 2000 219 224
29. KR Mills The natural history of central motor abnormalities in amyotrophic lateral sclerosis Brain 126 2003 2558 2566
30. M de Carvalho R Dengler A Eisen Electrodiagnostic criteria for diagnosis of ALS Clin Neurophysiol 119 2008 497 503
31. J Grosskreutz T Peschel A Unrath Whole brain-based computerized neuroimaging in ALS and other motor neuron disorders Amyotroph Lateral Scler 9 2008 238 248
32. H Mitsumoto AM Ulug SL Pullman Quantitative objective markers for upper and lower motor neuron dysfunction in ALS Neurology 68 2007 1402 1410
33. M Swash D Ingram Preclinical and subclinical events in motor neuron disease J Neurol Neurosurg Psychiatry 51 1988 165 168
34. M de Carvalho M Swash The onset of amyotrophic lateral sclerosis J Neurol Neurosurg Psychiatry 77 2006 388 389
35. MC Tartaglia A Rowe K Findlater Differentiation between primary lateral sclerosis and amyotrophic lateral sclerosis: examination of symptoms and signs at disease onset and during follow-up Arch Neurol 64 2007 232 236
36. M de Carvalho M Scotto M Swash Clinical patterns in progressive muscular atrophy (PMA): a prospective study Amyotroph Lateral Scler 8 2007 296 299
37. DJ Wilkinson Stochastic modeling for quantitative description of heterogeneous biological systems Nat Rev Gen 1 2009 122 133
38. S Zacchigna D Lambrechts P Carmeliet Neurovascular signaling defects in neurodegeneration Nat Rev Neurosci 9 2008 169 181
39. J Pradas L Finison PL Andres The natural history of amyotrophic lateral sclerosis and the use of natural history controls in therapeutic trials Neurology 43 1993 751 755
40. M Nagai DB Re T Nagata Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons Nat Neurosci 10 2007 615 622
41. C Armon MC Graves D Moses Linear estimates of disease progression predict survival in patients with amyotrophic lateral sclerosis Muscle Nerve 23 2000 874 882
42. T Magnus M Beck R Giess Disease progression in amyotrophic lateral sclerosis: predictors of survival Muscle Nerve 25 2002 709 714
43. PM Andersen P Nilsson ML Keränen Phenotypic heterogeneity in motor neuron disease patients with CuZn-superoxide dismutase mutations in Scandinavia Brain 120 1997 1723 1737
44. M Newmann DM Sampathu LK Kwong Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Science 314 2006 130 133
45. T Arai LM Hasegawa H Akiyama TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Biochem Biophys Res Commun 351 2006 602 611
46. A Beleza-Meireles A Al-Chalabi Genetic studies of amyotrophic lateral sclerosis: controversies and perspectives Amyotroph Lateral Scler 10 2009 1 14
47. C Lagier-Tourenne DW Cleveland Rethinking ALS: the FUS about TDP-43 Cell 136 2009 1001 1004
48. IM Parhad AW Clark KD Barron SB Staunton Diaphragmatic paralysis in motor neuron disease. Report of two cases and a review of the literature Neurology 28 1978 18 22
49. M de Carvalho T Matias F Coelho T Evangelista A Pinto ML Luis Motor neuron disease presenting with respiratory failure J Neurol Sci 139 suppl 1996 117 122
50. R Chen F Grand'Maison MJ Strong DA Ramsay CF Bolton Motor neuron disease presenting as acute respiratory failure: a clinical and pathological study J Neurol Neurosurg Psychiatry 60 1996 455 458
51. H Hayashi S Kato A Kawada Amyotrophic lateral sclerosis patients living beyond respiratory failure J Neurol Sci 105 1991 73 78
52. MB Graeber Twenty-first century brain banking: at the crossroads Acta Neuropathol 115 2008 493 496