Pathological heterogeneity in amyotrophic lateral sclerosis with FUS mutations: Two distinct patterns correlating with disease severity and mutation

Acta Neuropathologica

Volumn 122, Issue 1, 2011, Pages 87-98

  Mackenzie, Ian R A ^a   Ansorge, Olaf ^b   Strong, Michael ^c   Bilbao, Juan ^d   Zinman, Lorne ^e   Ang, Lee Cyn ^c   Baker, Matt ^f   Stewart, Heather ^a   Eisen, Andrew ^a   Rademakers, Rosa ^f   Neumann, Manuela ^g  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c LONDON HEALTH SCIENCES CENTRE   (Canada)

^d SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

^f MAYO GRADUATE SCHOOL   (United States)

^g UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Amyotrophic lateral sclerosis (ALS); Basophilic inclusions; Fused in sarcoma (FUS)

Indexed keywords

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BASOPHIL; CELL INCLUSION; CELL LABELING; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; FEMALE; FRONTOTEMPORAL DEMENTIA; FUSED IN SARCOMA GENE; GENE; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; HUMAN; IMMUNOREACTIVITY; MALE; NERVE CELL; NEUROPATHOLOGY; OLIGODENDROGLIA; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AMYOTROPHIC LATERAL SCLEROSIS; FEMALE; HUMANS; INCLUSION BODIES; MALE; MEDULLA OBLONGATA; MIDDLE AGED; MOTOR CORTEX; MOTOR NEURONS; MUTATION; NEUROGLIA; RNA-BINDING PROTEIN FUS; SEVERITY OF ILLNESS INDEX; SPINAL CORD; YOUNG ADULT;

EID: 79959615773     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-011-0838-7     Document Type: Article

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