A safe, blood-brain barrier permeable triphenylmethane dye inhibits amyloid-β neurotoxicity by generating nontoxic aggregates

ACS Chemical Neuroscience

Volumn 2, Issue 11, 2011, Pages 645-657

  Wong, H Edward ^a   Qi, Wei ^a   Choi, Hyung Min ^a,c   Fernandez, Erik J ^a   Kwon, Inchan ^a,b  

^a University of Virginia   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c Soongsil University   (South Korea)

Author keywords

Alzheimer's disease; amyloid ; Brilliant blue; fibrils; nontoxic aggregates; oligomers

Indexed keywords

AMYLOID BETA PROTEIN; BRILLIANT BLUE; FOOD DYE; MALACHITE GREEN; TRIPHENYLMETHANE DERIVATIVE;

ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN AGGREGATION; SPINAL CORD INJURY;

AMYLOID BETA-PEPTIDES; BLOOD-BRAIN BARRIER; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORESCENT DYES; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; NERVE FIBERS; NEUROPROTECTIVE AGENTS; OXAZINES; PROTEIN BINDING; ROSANILINE DYES; THIAZOLES; TRITYL COMPOUNDS; XANTHENES;

EID: 81455136028     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn200056g     Document Type: Article

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