Biflavonoids are superior to monoflavonoids in inhibiting amyloid-β toxicity and fibrillogenesis via accumulation of nontoxic oligomer-like structures

Biochemistry

Volumn 50, Issue 13, 2011, Pages 2445-2455

  Thapa, Arjun ^a,b   Woo, Eun Rhan ^a   Chi, Eva Y ^b   Sharoar, Md Golam ^a,c   Jin, Hong Guang ^a   Shin, Song Yub ^a   Park, Il Seon ^a  

^a Chosun University   (South Korea)

^b MSC01 1070   (United States)

^c UNIVERSITY OF RAJSHAHI   (Bangladesh)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER'S DISEASE; DIFFERENTIAL EFFECT; FIBRILLOGENESIS; INSOLUBLE FIBRILS; OLIGOMERIC STRUCTURE; SMALL MOLECULES; THERAPEUTIC STRATEGY;

FUNCTIONAL POLYMERS; GLYCOPROTEINS; OLIGOMERS; PEPTIDES; POLYMERIZATION;

TOXICITY;

2',8'' BIAPIGENIN; AMENTOFLAVONE; AMYLOID BETA PROTEIN[1-42]; APIGENIN; FLAVONOID; SUMAFLAVONE; TAIWANIAFLAVONE; UNCLASSIFIED DRUG;

ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; FIBER; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL; PROTEIN STRUCTURE;

AMYLOID; AMYLOID BETA-PEPTIDES; APIGENIN; BIFLAVONOIDS; CASPASES; CELL LINE; CELL SURVIVAL; CIRCULAR DICHROISM; FLAVONES; FLAVONOIDS; FLUORESCENT DYES; HUMANS; KINETICS; MICROSCOPY, ELECTRON, TRANSMISSION; NEURONS; PEPTIDE FRAGMENTS; PHENOLS; SOLUBILITY; THIAZOLES;

EID: 79953199374     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101731d     Document Type: Article

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