Mechanism of thioflavin T binding to amyloid fibrils

Journal of Structural Biology

Volumn 151, Issue 3, 2005, Pages 229-238

  Khurana, Ritu ^a,b,c   Coleman, Chris ^a   Ionescu Zanetti, Cristian ^a   Carter, Sue A ^a   Krishna, Vinay ^b   Grover, Rajesh K ^b   Roy, Raja ^b   Singh, Shashi ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

^c CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

Amyloid binding dyes; Atomic force microscopy; Critical micellar concentration; Fluorescence enhancement; Thioflavin T micelles

Indexed keywords

AMYLOID; THIOFLAVINE;

AQUEOUS SOLUTION; ARTICLE; ATOMIC FORCE MICROSCOPY; BINDING AFFINITY; CALCULATION; CONCENTRATION (PARAMETERS); CONDUCTANCE; EXCITATION; FIBER; FLUORESCENCE; MICELLE; PH MEASUREMENT; PRIORITY JOURNAL;

AMYLOID; BINDING SITES; DEUTERIUM; FLUORESCENCE; FLUORESCENCE POLARIZATION; FLUORESCENT DYES; HYDROGEN-ION CONCENTRATION; MICELLES; MICROSCOPY, ATOMIC FORCE; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; SOLUTIONS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THIAZOLES; WATER;

EID: 25144489633     PISSN: 10478477     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsb.2005.06.006     Document Type: Article

References (19)

1. T. Ban, D. Hamada, K. Hasegawa, H. Naiki, and Y. Goto Direct observation of amyloid fibril growth monitored by thioflavin T fluorescence J. Biol. Chem. 278 19 2003 16462 16465
2. M. Canete, A. Villanueva, A. Juarranz, and J.C. Stockert A study of interaction of thioflavine T with DNA: evidence for intercalation Cell. Mol. Biol. 33 2 1987 191 199
3. W.J. Checovich, R.E. Bolger, and T. Burke Nature 375 6528 1995 254 256
4. J.R. Hobbs, and A.D. Morgan Fluorescence microscopy with thioflavine-t in the diagnosis of amyloid J. Pathol. Bacteriol. 86 1963 437 442
5. C. Ionescu-Zanetti, R. Khurana, J.R. Gillespie, J.S. Petrick, L.C. Trabachino, L.J. Minert, S.A. Carter, and A.L. Fink Monitoring the assembly of Ig light chain amyloid fibrils by atomic force microscopy Proc. Natl. Acad. Sci. USA 96 23 1999 13175 13179
6. C.S. Johnson Jr. Diffusion ordered nuclear magnetic resonance spectroscopy: principles and applications Prog. Nuclear Magn. Reson. Spectrosc. 34 1999 203 256
7. G. Kelényi On the histochemistry of azo group-free thiazole dyes J. Histochem. Cytochem. 15 3 1967 172 180
8. R. Khurana, C. Ionescu-Zanetti, M. Pope, J. Li, L. Nielsen, M. Ramirez-Alvarado, L. Regan, A.L. Fink, and S.A. Carter A general model for amyloid fibril assembly based on morphological studies using atomic force microscopy Biophys. J. 85 2 2003 1135 1144
9. R. Khurana, V.N. Uversky, L. Nielsen, and A.L. Fink Is Congo red an amyloid specific dye J. Biol. Chem. 276 25 2001 22715 22721
10. W.E. Klunk, Y. Wang, G.F. Huang, M.L. Debnath, D.P. Holt, and C.A. Mathis Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain Life Sci. 69 13 2001 1471 1484
11. M.R.H. Krebs, E.H.C. Bromley, and A.M. Donald The binding of thioflavin-T to amyloid fibrils: localization and implications J. Struct. Biol. 149 2005 30 37
12. N.D. Lazo, and D.T. Downing Beta-helical fibrils from a model peptide Biochem. Biophys. Res. Commun. 235 3 1997 675 679
13. H. LeVine III Thioflavine T interaction with synthetic Alzheimer's disease β-amyloid peptides: detection of amyloid aggregation in solution Protein Sci. 2 1993 404 410
14. H. LeVine III Thioflavine T interaction with amyloid β-sheet structures Amyloid Int. J. Exp. Clin. Invest. 2 1995 1 6
15. P. Mukerjee, and K.J. Mysels Critical Micelle Concentrations of Aqueous Surfactant Systems 1971 National Bureau of Standards Washington, DC, USA
16. H. Naiki, K. Higuchi, M. Hosokawa, and T. Takeda Fluorometric determination of amyloid fibrils in-vitro using the fluorescent dye, thioflavin T1 Anal. Biochem. 177 1989 244 249
17. S.M. Saeed, and G. Fine Thioflavin-T for amyloid detection Am. J. Clin. Pathol. 47 5 1967 588 593
18. P.S. Vassar, and C.F.A. Culling Fluorescent stains with special reference to amyloid and connective tissues Arch. Pathol. 68 1959 487 494
19. J. Wall, C.L. Murphy, and A. Solomon In vitro immunoglobulin light chain fibrillogenesis Methods Enzymol. 309 1999 204 217