Bacterial type i signal peptidases as antibiotic targets

Future Microbiology

Volumn 6, Issue 11, 2011, Pages 1279-1296

  Rao Cv, Smitha ^a   Anné, Jozef ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

5S penems; Antibiotic target; Arylomycin; High throughput screening; LepB; Novel antibiotic; Protein secretion; Ser Lys dyad; Signal peptidase

Indexed keywords

6 (ACETOXYETHYL)PENEM 3 CARBOXYLATE; ARYLOMYCIN A2; ARYLOMYCIN B2; ARYLOMYCIN C16; ARYLOMYCIN DERIVATIVE; BAL 0019193; BETA SULTAM DERIVATIVE; ENZYME INHIBITOR; LIPOGLYCOPEPTIDE DERIVATIVE; LIPOPEPTIDE; PENEM DERIVATIVE; POLYPEPTIDE ANTIBIOTIC AGENT; SIGNAL PEPTIDASE I; SIGNAL PEPTIDASE I INHIBITOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIBACTERIAL ACTIVITY; CATALYSIS; DRUG DESIGN; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME SPECIFICITY; HIGH THROUGHPUT SCREENING; HUMAN; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; REVIEW; STRUCTURE ANALYSIS;

ANTI-BACTERIAL AGENTS; ASPARTIC ACID ENDOPEPTIDASES; BACTERIA; ENZYME INHIBITORS; HUMANS;

BACTERIA (MICROORGANISMS); EUKARYOTA;

EID: 81255208135     PISSN: 17460913     EISSN: 17460921     Source Type: Journal    
DOI: 10.2217/fmb.11.109     Document Type: Review

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