Novel lipoglycopeptides as inhibitors of bacterial signal peptidase I

Journal of Biological Chemistry

Volumn 279, Issue 35, 2004, Pages 36250-36258

  Kulanthaivel, Palaniappan ^a   Kreuzman, Adam J ^a   Strege, Mark A ^a   Belvo, Matthew D ^a   Smitka, Tim A ^a   Clemens, Matthew ^a   Swartling, James B ^a   Minton, Kristina L ^a   Zheng, Feng ^a   Angleton, Eddie L ^a   Mullen, Deborah ^a   Jungheim, Louis N ^a   Klimkowski, Valentine J ^a   Nicas, Thalia I ^a   Thompson, Richard C ^a   Peng, Sheng Bin ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BIOCHEMISTRY; ESCHERICHIA COLI; NUCLEAR MAGNETIC RESONANCE;

ANTIBACTERIAL AGENTS; BIOCHEMICAL ANALYSIS;

ENZYME INHIBITION;

ENZYME INHIBITOR; FATTY ACID; GLYCOPEPTIDE; LIPOGLYCOPEPTIDE DERIVATIVE; N METHYLPHENYLGLYCINE; NORFLOXACIN; PENICILLIN G; SIGNAL PEPTIDASE I; SIGNAL PEPTIDASE I INHIBITOR; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBACTERIAL ACTIVITY; ARTICLE; COMPETITIVE INHIBITION; DRUG ISOLATION; DRUG STRUCTURE; ENZYME INHIBITION; ESCHERICHIA COLI; NONHUMAN; OXIDATION KINETICS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SECRETION; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; STREPTOMYCES; STRUCTURE ACTIVITY RELATION;

BETA-LACTAMASES; BINDING, COMPETITIVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; ESCHERICHIA COLI; FERMENTATION; GLYCINE; GLYCOPEPTIDES; GRAM-NEGATIVE BACTERIA; INHIBITORY CONCENTRATION 50; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MEMBRANE PROTEINS; MODELS, CHEMICAL; PEPTIDES; PROTEIN SORTING SIGNALS; PROTONS; SERINE ENDOPEPTIDASES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; STREPTOMYCES; TIME FACTORS;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; POSIBACTERIA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE; STREPTOMYCES; STREPTOMYCES SP.; UNCULTURED ACTINOMYCETE;

EID: 4344563166     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M405884200     Document Type: Article

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