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Volumn 19, Issue 10, 2009, Pages 2880-2883

Corrigendum to "Substrate based peptide aldehyde inhibits bacterial type I signal peptidase" [Bioorg. Med. Chem. Lett. 19 (2009) 2880] (DOI:10.1016/j.bmcl.2009.03.064);Substrate based peptide aldehyde inhibits bacterial type I signal peptidase

Author keywords

Antibiotics; Peptides; Signal peptidase; Structure activity relationship

Indexed keywords

ALDEHYDE DERIVATIVE; AMINO ACID; ENZYME INHIBITOR; LIPOPEPTIDE; PEPTIDE DERIVATIVE; SIGNAL PEPTIDASE I; SIGNAL PEPTIDASE I INHIBITOR; UNCLASSIFIED DRUG;

EID: 65349139603     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.03.169     Document Type: Erratum
Times cited : (30)

References (26)
  • 22
    • 65349111737 scopus 로고    scopus 로고
    • note
    • Solid phase peptide synthesis was performed on Wang resin using classical coupling reagents for peptide bond formation and Fmoc protected amino acids. Synthesis was terminated by N-terminal decanoylation followed by side chain deprotection and cleavage from the solid support using a mixture of TFA/water/thioanisole (95:5:5) following the general deprotection-cleavage procedure. Crude peptides were purified by semi-preparative RP-HPLC. Compounds were characterized by accurate mass spectrometry.
  • 25
    • 65349158118 scopus 로고    scopus 로고
    • note
    • Compound 11 was purchased from Cambridge Peptides. The synthesis was carried out on a Weinreb AM resin followed by the reduction of the Weinreb amide to the protected peptide aldehyde by lithium aluminum hydride. Finally protecting groups were removed by treatment with trifluoro acetic acid. The crude peptide aldehyde was purified by HPLC.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.