Initial efforts toward the optimization of arylomycins for antibiotic activity

Journal of Medicinal Chemistry

Volumn 54, Issue 14, 2011, Pages 4954-4963

  Roberts, Tucker C ^a   Schallenberger, Mark A ^a   Liu, Jian ^a   Smith, Peter A ^a   Romesberg, Floyd E ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ARYLOMYCIN; ARYLOMYCIN A; ARYLOMYCIN A2; ARYLOMYCIN B; ARYLOMYCIN C16; ARYLOMYCIN C18; LIPOPEPTIDE; NATURAL PRODUCT; SIGNAL PEPTIDASE I; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIUM ISOLATE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DERIVATIZATION; DRUG TARGETING; ESCHERICHIA COLI; HUMAN; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS;

ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; LIPOPEPTIDES; MEMBRANE PROTEINS; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; OLIGOPEPTIDES; PEPTIDES, CYCLIC; PSEUDOMONAS AERUGINOSA; SERINE ENDOPEPTIDASES; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79960641005     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm1016126     Document Type: Article

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