Altered - 3 Substrate specificity of Escherichia coli signal peptidase 1 mutants as revealed by screening a combinatorial peptide library

Journal of Biological Chemistry

Volumn 282, Issue 1, 2007, Pages 417-425

  Ekici, Özlem Doǧan ^a   Karla, Andrew ^a   Paetzel, Mark ^c   Lively, Mark O ^b   Pei, Dehua ^a   Dalbey, Ross E ^a,d  

^a OHIO STATE UNIVERSITY   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c SIMON FRASER UNIVERSITY   (Canada)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALIPHATIC RESIDUES; FLUORESCENCE RESONANCE ENERGY TRANSFER; SIGNAL PEPTIDASE FUNCTIONS;

AMINO ACIDS; CELL MEMBRANES; ENERGY TRANSFER; ESCHERICHIA COLI; FLUORESCENCE; MUTAGENESIS;

ENZYMES;

ARGININE; GLUTAMINE; MUTANT PROTEIN; PEPTIDE LIBRARY; SIGNAL PEPTIDASE I; TYROSINE; ASPARAGINE; ISOLEUCINE; MEMBRANE PROTEIN; PEPTIDE; PHENYLALANINE; SERINE PROTEINASE; TYPE I SIGNAL PEPTIDASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ESCHERICHIA COLI; FLUORESCENCE RESONANCE ENERGY TRANSFER; IN VITRO SELECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENE LIBRARY; GENETICS; MUTATION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE;

ESCHERICHIA COLI;

ASPARAGINE; ESCHERICHIA COLI; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE LIBRARY; ISOLEUCINE; MEMBRANE PROTEINS; MODELS, CHEMICAL; MODELS, MOLECULAR; MUTATION; PEPTIDE LIBRARY; PEPTIDES; PHENYLALANINE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SERINE ENDOPEPTIDASES; SUBSTRATE SPECIFICITY;

EID: 33846985979     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M608779200     Document Type: Article

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