-
1
-
-
33645362213
-
UNC-6/Netrin induces neuronal asymmetry and defines the site of axon formation
-
Adler, C. E., Fetter, R. D. and Bargmann, C. I. (2006). UNC-6/Netrin induces neuronal asymmetry and defines the site of axon formation. Nat. Neurosci. 9, 511-518.
-
(2006)
Nat. Neurosci
, vol.9
, pp. 511-518
-
-
Adler, C.E.1
Fetter, R.D.2
Bargmann, C.I.3
-
2
-
-
0031127305
-
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha
-
Alessi, D. R., James, S. R., Downes, C. P., Holmes, A. B., Gaffney, P. R., Reese, C. B. and Cohen, P. (1997). Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha. Curr. Biol. 7, 261-269.
-
(1997)
Curr. Biol
, vol.7
, pp. 261-269
-
-
Alessi, D.R.1
James, S.R.2
Downes, C.P.3
Holmes, A.B.4
Gaffney, P.R.5
Reese, C.B.6
Cohen, P.7
-
4
-
-
0034743423
-
A regulatory cascade of three homeobox genes, ceh-10, ttx-3 and ceh-23, controls cell fate specification of a defined interneuron class in C. elegans
-
Altun-Gultekin, Z., Andachi, Y., Tsalik, E. L., Pilgrim, D., Kohara, Y. and Hobert, O. (2001). A regulatory cascade of three homeobox genes, ceh-10, ttx-3 and ceh-23, controls cell fate specification of a defined interneuron class in C. elegans. Development 128, 1951-1969.
-
(2001)
Development
, vol.128
, pp. 1951-1969
-
-
Altun-Gultekin, Z.1
Andachi, Y.2
Tsalik, E.L.3
Pilgrim, D.4
Kohara, Y.5
Hobert, O.6
-
5
-
-
0030770814
-
Deletion of PTEN in a patient with Bannayan-Riley-Ruvalcaba syndrome suggests allelism with Cowden disease
-
Arch, E. M., Goodman, B. K., Van Wesep, R. A., Liaw, D., Clarke, K., Parsons, R., McKusick, V. A. and Geraghty, M. T. (1997). Deletion of PTEN in a patient with Bannayan-Riley-Ruvalcaba syndrome suggests allelism with Cowden disease. Am. J. Med. Genet. 71, 489-493.
-
(1997)
Am. J. Med. Genet
, vol.71
, pp. 489-493
-
-
Arch, E.M.1
Goodman, B.K.2
van Wesep, R.A.3
Liaw, D.4
Clarke, K.5
Parsons, R.6
McKusick, V.A.7
Geraghty, M.T.8
-
6
-
-
41849087003
-
FOXO animal models reveal a variety of diverse roles for FOXO transcription factors
-
Arden, K. C. (2008). FOXO animal models reveal a variety of diverse roles for FOXO transcription factors. Oncogene 27, 2345-2350.
-
(2008)
Oncogene
, vol.27
, pp. 2345-2350
-
-
Arden, K.C.1
-
7
-
-
0035733762
-
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease
-
Backman, S. A., Stambolic, V., Suzuki, A., Haight, J., Elia, A., Pretorius, J., Tsao, M. S., Shannon, P., Bolon, B., Ivy, G. O. et al. (2001). Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease. Nat. Genet. 29, 396-403.
-
(2001)
Nat. Genet
, vol.29
, pp. 396-403
-
-
Backman, S.A.1
Stambolic, V.2
Suzuki, A.3
Haight, J.4
Elia, A.5
Pretorius, J.6
Tsao, M.S.7
Shannon, P.8
Bolon, B.9
Ivy, G.O.10
-
8
-
-
0037323903
-
Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors
-
Birkenkamp, K. U. and Coffer, P. J. (2003). Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors. Biochem. Soc. Trans. 31, 292-297.
-
(2003)
Biochem. Soc Trans
, vol.31
, pp. 292-297
-
-
Birkenkamp, K.U.1
Coffer, P.J.2
-
9
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J. and Greenberg, M. E. (1999). Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96, 857-868.
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
Arden, K.C.8
Blenis, J.9
Greenberg, M.E.10
-
10
-
-
0017076266
-
The life cycle of the nematode Caenorhabditis elegans. I. Wild-type growth and reproduction
-
Byerly, L., Cassada, R. C. and Russell, R. L. (1976). The life cycle of the nematode Caenorhabditis elegans. I. Wild-type growth and reproduction. Dev. Biol. 51, 23-33.
-
(1976)
Dev. Biol
, vol.51
, pp. 23-33
-
-
Byerly, L.1
Cassada, R.C.2
Russell, R.L.3
-
11
-
-
0003779173
-
Histology of the nervous system of man and vertebrates
-
Cajal, S. R. Y. (1995). Histology of the nervous system of man and vertebrates. New York: Oxford University Press.
-
(1995)
New York: Oxford University Press
-
-
Cajal, S.R.Y.1
-
12
-
-
35148813033
-
Glia promote local synaptogenesis through UNC-6 (netrin) signaling in C. elegans
-
Colon-Ramos, D. A., Margeta, M. A. and Shen, K. (2007). Glia promote local synaptogenesis through UNC-6 (netrin) signaling in C. elegans. Science 318, 103-106.
-
(2007)
Science
, vol.318
, pp. 103-106
-
-
Colon-Ramos, D.A.1
Margeta, M.A.2
Shen, K.3
-
13
-
-
34247174760
-
Phosphoinositide 3-kinase signalling events controlling axonal morphogenesis
-
Cosker, K. E. and Eickholt, B. J. (2007). Phosphoinositide 3-kinase signalling events controlling axonal morphogenesis. Biochem. Soc. Trans. 35, 207-210.
-
(2007)
Biochem. Soc Trans
, vol.35
, pp. 207-210
-
-
Cosker, K.E.1
Eickholt, B.J.2
-
14
-
-
77950933448
-
A FOXOPak1 transcriptional pathway controls neuronal polarity
-
de la Torre-Ubieta, L., Gaudilliere, B., Yang, Y., Ikeuchi, Y., Yamada, T., DiBacco, S., Stegmuller, J., Schuller, U., Salih, D. A., Rowitch, D. et al. (2010). A FOXOPak1 transcriptional pathway controls neuronal polarity. Genes Dev. 24, 799-813.
-
(2010)
Genes Dev
, vol.24
, pp. 799-813
-
-
de la Torre-Ubieta, L.1
Gaudilliere, B.2
Yang, Y.3
Ikeuchi, Y.4
Yamada, T.5
Dibacco, S.6
Stegmuller, J.7
Schuller, U.8
Salih, D.A.9
Rowitch, D.10
-
15
-
-
0028807085
-
The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans
-
Dorman, J. B., Albinder, B., Shroyer, T. and Kenyon, C. (1995). The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans. Genetics 141, 1399-1406.
-
(1995)
Genetics
, vol.141
, pp. 1399-1406
-
-
Dorman, J.B.1
Albinder, B.2
Shroyer, T.3
Kenyon, C.4
-
16
-
-
41149165141
-
Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase
-
Eickholt, B. J., Ahmed, A. I., Davies, M., Papakonstanti, E. A., Pearce, W., Starkey, M. L., Bilancio, A., Need, A. C., Smith, A. J., Hall, S. M. et al. (2007). Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase. PLoS ONE 2, e869.
-
(2007)
PLoS ONE
, vol.2
-
-
Eickholt, B.J.1
Ahmed, A.I.2
Davies, M.3
Papakonstanti, E.A.4
Pearce, W.5
Starkey, M.L.6
Bilancio, A.7
Need, A.C.8
Smith, A.J.9
Hall, S.M.10
-
17
-
-
7444264727
-
Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo
-
Fraser, M. M., Zhu, X., Kwon, C. H., Uhlmann, E. J., Gutmann, D. H. and Baker, S. J. (2004). Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo. Cancer Res. 64, 7773-7779.
-
(2004)
Cancer Res
, vol.64
, pp. 7773-7779
-
-
Fraser, M.M.1
Zhu, X.2
Kwon, C.H.3
Uhlmann, E.J.4
Gutmann, D.H.5
Baker, S.J.6
-
18
-
-
0032981396
-
Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene
-
Gil, E. B., Malone Link, E., Liu, L. X., Johnson, C. D. and Lees, J. A. (1999). Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene. Proc. Natl. Acad. Sci. USA 96, 2925-2930.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2925-2930
-
-
Gil, E.B.1
Malone Link, E.2
Liu, L.X.3
Johnson, C.D.4
Lees, J.A.5
-
19
-
-
18844472952
-
Expression of the PTEN tumour suppressor protein during human development
-
Gimm, O., Attie-Bitach, T., Lees, J. A., Vekemans, M. and Eng, C. (2000). Expression of the PTEN tumour suppressor protein during human development. Hum. Mol. Genet. 9, 1633-1639.
-
(2000)
Hum. Mol. Genet
, vol.9
, pp. 1633-1639
-
-
Gimm, O.1
Attie-Bitach, T.2
Lees, J.A.3
Vekemans, M.4
Eng, C.5
-
20
-
-
0042566203
-
The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells
-
Higuchi, M., Onishi, K., Masuyama, N. and Gotoh, Y. (2003). The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells. Genes Cells 8, 657-669.
-
(2003)
Genes Cells
, vol.8
, pp. 657-669
-
-
Higuchi, M.1
Onishi, K.2
Masuyama, N.3
Gotoh, Y.4
-
21
-
-
0030765073
-
Regulation of interneuron function in the C. elegans thermoregulatory pathway by the ttx-3 LIM homeobox gene
-
Hobert, O., Mori, I., Yamashita, Y., Honda, H., Ohshima, Y., Liu, Y. and Ruvkun, G. (1997). Regulation of interneuron function in the C. elegans thermoregulatory pathway by the ttx-3 LIM homeobox gene. Neuron 19, 345-357.
-
(1997)
Neuron
, vol.19
, pp. 345-357
-
-
Hobert, O.1
Mori, I.2
Yamashita, Y.3
Honda, H.4
Ohshima, Y.5
Liu, Y.6
Ruvkun, G.7
-
22
-
-
30444442827
-
Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain
-
Hoekman, M. F., Jacobs, F. M., Smidt, M. P. and Burbach, J. P. (2006). Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain. Gene Expr. Patterns 6, 134-140.
-
(2006)
Gene Expr. Patterns
, vol.6
, pp. 134-140
-
-
Hoekman, M.F.1
Jacobs, F.M.2
Smidt, M.P.3
Burbach, J.P.4
-
23
-
-
84971678127
-
Genetic analysis of a large autosomal region in Caenorhabditis Elegans by the use of a free duplication
-
Howell, A. M., Gilmour, S. G., Mancebo, R. A. and Rose, A. M. (1987). Genetic analysis of a large autosomal region in Caenorhabditis Elegans by the use of a free duplication. Genet. Res. 49, 207-213.
-
(1987)
Genet Res
, vol.49
, pp. 207-213
-
-
Howell, A.M.1
Gilmour, S.G.2
Mancebo, R.A.3
Rose, A.M.4
-
24
-
-
4544311861
-
The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
-
Jia, K., Chen, D. and Riddle, D. L. (2004). The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 131, 3897-3906.
-
(2004)
Development
, vol.131
, pp. 3897-3906
-
-
Jia, K.1
Chen, D.2
Riddle, D.L.3
-
25
-
-
78649793287
-
PTEN suppression promotes neurite development exclusively in differentiating PC12 cells via PI3-kinase and MAP kinase signaling
-
Jia, L., Ji, S., Maillet, J. C. and Zhang, X. (2010). PTEN suppression promotes neurite development exclusively in differentiating PC12 cells via PI3-kinase and MAP kinase signaling. J. Cell. Biochem. 111, 1390-1400.
-
(2010)
J. Cell. Biochem
, vol.111
, pp. 1390-1400
-
-
Jia, L.1
Ji, S.2
Maillet, J.C.3
Zhang, X.4
-
26
-
-
0037178786
-
MTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
Kim, D. H., Sarbassov, D. D., Ali, S. M., King, J. E., Latek, R. R., Erdjument-Bromage, H., Tempst, P. and Sabatini, D. M. (2002). mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 110, 163-175.
-
(2002)
Cell
, vol.110
, pp. 163-175
-
-
Kim, D.H.1
Sarbassov, D.D.2
Ali, S.M.3
King, J.E.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
27
-
-
0030813398
-
Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
-
Kimura, K. D., Tissenbaum, H. A., Liu, Y. and Ruvkun, G. (1997). daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277, 942-946.
-
(1997)
Science
, vol.277
, pp. 942-946
-
-
Kimura, K.D.1
Tissenbaum, H.A.2
Liu, Y.G.3
-
28
-
-
33751116842
-
Insulin-like signaling and the neural circuit for integrative behavior in C
-
Kodama, E., Kuhara, A., Mohri-Shiomi, A., Kimura, K. D., Okumura, M., Tomioka, M., Iino, Y. and Mori, I. (2006). Insulin-like signaling and the neural circuit for integrative behavior in C. elegans. Genes Dev. 20, 2955-2960.
-
(2006)
Elegans. Genes Dev
, vol.20
, pp. 2955-2960
-
-
Kodama, E.1
Kuhara, A.2
Mohri-Shiomi, A.3
Kimura, K.D.4
Okumura, M.5
Tomioka, M.6
Iino, Y.7
Mori, I.8
-
29
-
-
0036282745
-
Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery
-
Konishi, Y., Lehtinen, M., Donovan, N. and Bonni, A. (2002). Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Mol. Cell 9, 1005-1016.
-
(2002)
Mol. Cell
, vol.9
, pp. 1005-1016
-
-
Konishi, Y.1
Lehtinen, M.2
Donovan, N.3
Bonni, A.4
-
30
-
-
0035734381
-
Pten regulates neuronal soma size: A mouse model of Lhermitte-Duclos disease
-
Kwon, C. H., Zhu, X., Zhang, J., Knoop, L. L., Tharp, R., Smeyne, R. J., Eberhart, C. G., Burger, P. C. and Baker, S. J. (2001). Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease. Nat. Genet. 29, 404-411.
-
(2001)
Nat. Genet
, vol.29
, pp. 404-411
-
-
Kwon, C.H.1
Zhu, X.2
Zhang, J.3
Knoop, L.L.4
Tharp, R.5
Smeyne, R.J.6
Eberhart, C.G.7
Burger, P.C.8
Baker, S.J.9
-
31
-
-
0242268407
-
MTor is required for hypertrophy of Pten-deficient neuronal soma in vivo
-
Kwon, C. H., Zhu, X., Zhang, J. and Baker, S. J. (2003). mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo. Proc. Natl. Acad. Sci. USA 100, 12923-12928.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12923-12928
-
-
Kwon, C.H.1
Zhu, X.2
Zhang, J.3
Baker, S.J.4
-
32
-
-
33646142995
-
Pten regulates neuronal arborization and social interaction in mice
-
Kwon, C. H., Luikart, B. W., Powell, C. M., Zhou, J., Matheny, S. A., Zhang, W., Li, Y., Baker, S. J. and Parada, L. F. (2006). Pten regulates neuronal arborization and social interaction in mice. Neuron 50, 377-388.
-
(2006)
Neuron
, vol.50
, pp. 377-388
-
-
Kwon, C.H.1
Luikart, B.W.2
Powell, C.M.3
Zhou, J.4
Matheny, S.A.5
Zhang, W.6
Li, Y.7
Baker, S.J.8
Parada, L.F.9
-
33
-
-
77954959936
-
A new DAF-16 isoform regulates longevity
-
Kwon, E. S., Narasimhan, S. D., Yen, K. and Tissenbaum, H. A. (2010). A new DAF-16 isoform regulates longevity. Nature 466, 498-502.
-
(2010)
Nature
, vol.466
, pp. 498-502
-
-
Kwon, E.S.1
Narasimhan, S.D.2
Yen, K.3
Tissenbaum, H.A.4
-
34
-
-
0034652102
-
A role for nuclear PTEN in neuronal differentiation
-
Lachyankar, M. B., Sultana, N., Schonhoff, C. M., Mitra, P., Poluha, W., Lambert, S., Quesenberry, P. J., Litofsky, N. S., Recht, L. D., Nabi, R. et al. (2000). A role for nuclear PTEN in neuronal differentiation. J. Neurosci. 20, 1404-1413.
-
(2000)
J. Neurosci
, vol.20
, pp. 1404-1413
-
-
Lachyankar, M.B.1
Sultana, N.2
Schonhoff, C.M.3
Mitra, P.4
Poluha, W.5
Lambert, S.6
Quesenberry, P.J.7
Litofsky, N.S.8
Recht, L.D.9
Nabi, R.10
-
35
-
-
0035846601
-
Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
-
Lee, R. Y., Hench, J. and Ruvkun, G. (2001). Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway. Curr. Biol. 11, 1950-1957.
-
(2001)
Curr. Biol
, vol.11
, pp. 1950-1957
-
-
Lee, R.Y.1
Hench, J.2
Ruvkun, G.3
-
36
-
-
33646934067
-
A conserved MSTFOXO signaling pathway mediates oxidative-stress responses and extends life span
-
Lehtinen, M. K., Yuan, Z., Boag, P. R., Yang, Y., Villen, J., Becker, E. B., DiBacco, S., de la Iglesia, N., Gygi, S., Blackwell, T. K. et al. (2006). A conserved MSTFOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell 125, 987-1001.
-
(2006)
Cell
, vol.125
, pp. 987-1001
-
-
Lehtinen, M.K.1
Yuan, Z.2
Boag, P.R.3
Yang, Y.4
Villen, J.5
Becker, E.B.6
Dibacco, S.7
de la Iglesia, N.8
Gygi, S.9
Blackwell, T.K.10
-
37
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R. et al. (1997). PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275, 1943-1947.
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.I.6
Puc, J.7
Miliaresis, C.8
Rodgers, L.9
McCombie, R.10
-
38
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw, D., Marsh, D. J., Li, J., Dahia, P. L., Wang, S. I., Zheng, Z., Bose, S., Call, K. M., Tsou, H. C., Peacocke, M. et al. (1997). Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat. Genet. 16, 64-67.
-
(1997)
Nat. Genet
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
Dahia, P.L.4
Wang, S.I.5
Zheng, Z.6
Bose, S.7
Call, K.M.8
Tsou, H.C.9
Peacocke, M.10
-
39
-
-
0030657540
-
An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
-
Lin, K., Dorman, J. B., Rodan, A. and Kenyon, C. (1997). daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278, 1319-1322.
-
Science
, vol.278
, pp. 1319-1322
-
-
Lin, K.1
Dorman, J.B.2
Rodan, A.3
Kenyon, C.4
-
40
-
-
0034967720
-
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
-
Lin, K., Hsin, H., Libina, N. and Kenyon, C. (2001). Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nat. Genet. 28, 139-145.
-
(2001)
Nat. Genet
, vol.28
, pp. 139-145
-
-
Lin, K.1
Hsin, H.2
Libina, N.3
Kenyon, C.4
-
41
-
-
0037015269
-
TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation
-
Long, X., Spycher, C., Han, Z. S., Rose, A. M., Muller, F. and Avruch, J. (2002). TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation. Curr. Biol. 12, 1448-1461.
-
(2002)
Curr. Biol
, vol.12
, pp. 1448-1461
-
-
Long, X.1
Spycher, C.2
Han, Z.S.3
Rose, A.M.4
Muller, F.5
Avruch, J.6
-
42
-
-
0029612196
-
A family of phosphoinositide 3-kinases in Drosophila identifies a new mediator of signal transduction
-
MacDougall, L. K., Domin, J. and Waterfield, M. D. (1995). A family of phosphoinositide 3-kinases in Drosophila identifies a new mediator of signal transduction. Curr. Biol. 5, 1404-1415.
-
(1995)
Curr. Biol
, vol.5
, pp. 1404-1415
-
-
Macdougall, L.K.1
Domin, J.2
Waterfield, M.D.3
-
43
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama, T. and Dixon, J. E. (1998). The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 273, 13375-13378.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
44
-
-
0031203265
-
Germline mutations in PTEN are present in Bannayan-Zonana syndrome
-
Marsh, D. J., Dahia, P. L., Zheng, Z., Liaw, D., Parsons, R., Gorlin, R. J. and Eng, C. (1997). Germline mutations in PTEN are present in Bannayan-Zonana syndrome. Nat. Genet. 16, 333-334.
-
(1997)
Nat. Genet
, vol.16
, pp. 333-334
-
-
Marsh, D.J.1
Dahia, P.L.2
Zheng, Z.3
Liaw, D.4
Parsons, R.5
Gorlin, R.J.6
Eng, C.7
-
45
-
-
25844512127
-
Lifespan and dauer regulation by tissue-specific activities of Caenorhabditis elegans DAF-18
-
Masse, I., Molin, L., Billaud, M. and Solari, F. (2005). Lifespan and dauer regulation by tissue-specific activities of Caenorhabditis elegans DAF-18. Dev. Biol. 286, 91-101.
-
(2005)
Dev. Biol
, vol.286
, pp. 91-101
-
-
Masse, I.1
Molin, L.2
Billaud, M.3
Solari, F.4
-
46
-
-
0038245261
-
Interfacial kinetic analysis of the tumour suppressor phosphatase, PTEN: Evidence for activation by anionic phospholipids
-
McConnachie, G., Pass, I., Walker, S. M. and Downes, C. P. (2003). Interfacial kinetic analysis of the tumour suppressor phosphatase, PTEN: evidence for activation by anionic phospholipids. Biochem. J. 371, 947-955.
-
(2003)
Biochem. J
, vol.371
, pp. 947-955
-
-
McConnachie, G.1
Pass, I.2
Walker, S.M.3
Downes, C.P.4
-
47
-
-
0029050730
-
Neural regulation of thermotaxis in Caenorhabditis elegans
-
Mori, I. and Ohshima, Y. (1995). Neural regulation of thermotaxis in Caenorhabditis elegans. Nature 376, 344-348.
-
(1995)
Nature
, vol.376
, pp. 344-348
-
-
Mori, I.1
Ohshima, Y.2
-
48
-
-
0029768753
-
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
-
Morris, J. Z., Tissenbaum, H. A. and Ruvkun, G. (1996). A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans. Nature 382, 536-539.
-
(1996)
Nature
, vol.382
, pp. 536-539
-
-
Morris, J.Z.1
Tissenbaum, H.A.2
Ruvkun, G.3
-
49
-
-
28044472729
-
Agingdependent and -independent modulation of associative learning behavior by insulin/insulin-like growth factor-1 signal in Caenorhabditis elegans
-
Murakami, H., Bessinger, K., Hellmann, J. and Murakami, S. (2005). Agingdependent and -independent modulation of associative learning behavior by insulin/insulin-like growth factor-1 signal in Caenorhabditis elegans. J. Neurosci. 25, 10894-10904.
-
(2005)
J. Neurosci
, vol.25
, pp. 10894-10904
-
-
Murakami, H.1
Bessinger, K.2
Hellmann, J.3
Murakami, S.4
-
50
-
-
1542723390
-
Inhibition of neuronal phenotype by PTEN in PC12 cells
-
Musatov, S., Roberts, J., Brooks, A. I., Pena, J., Betchen, S., Pfaff, D. W. and Kaplitt, M. G. (2004). Inhibition of neuronal phenotype by PTEN in PC12 cells. Proc. Natl. Acad. Sci. USA 101, 3627-3631.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3627-3631
-
-
Musatov, S.1
Roberts, J.2
Brooks, A.I.3
Pena, J.4
Betchen, S.5
Pfaff, D.W.6
Kaplitt, M.G.7
-
51
-
-
0030659557
-
The Fork head transcription factor DAF-16 transduces insulinlike metabolic and longevity signals in C. elegans
-
Ogg, S., Paradis, S., Gottlieb, S., Patterson, G. I., Lee, L., Tissenbaum, H. A. and Ruvkun, G. (1997). The Fork head transcription factor DAF-16 transduces insulinlike metabolic and longevity signals in C. elegans. Nature 389, 994-999.
-
(1997)
Nature
, vol.389
, pp. 994-999
-
-
Ogg, S.1
Paradis, S.2
Gottlieb, S.3
Patterson, G.I.4
Lee, L.5
Tissenbaum, H.A.6
Ruvkun, G.7
-
52
-
-
70350497348
-
FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis
-
Paik, J. H., Ding, Z., Narurkar, R., Ramkissoon, S., Muller, F., Kamoun, W. S., Chae, S. S., Zheng, H., Ying, H., Mahoney, J. et al. (2009). FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis. Cell Stem Cell 5, 540-553.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 540-553
-
-
Paik, J.H.1
Ding, Z.2
Narurkar, R.3
Ramkissoon, S.4
Muller, F.5
Kamoun, W.S.6
Chae, S.S.7
Zheng, H.8
Ying, H.9
Mahoney, J.10
-
53
-
-
0033151613
-
A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans
-
Paradis, S., Ailion, M., Toker, A., Thomas, J. H. and Ruvkun, G. (1999). A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans. Genes Dev. 13, 1438-1452.
-
(1999)
Genes Dev
, vol.13
, pp. 1438-1452
-
-
Paradis, S.1
Ailion, M.2
Toker, A.3
Thomas, J.H.4
Ruvkun, G.5
-
54
-
-
0031035046
-
Development of polarity in cerebellar granule neurons
-
Powell, S. K., Rivas, R. J., Rodriguez-Boulan, E. and Hatten, M. E. (1997). Development of polarity in cerebellar granule neurons. J. Neurobiol. 32, 223-236.
-
(1997)
J. Neurobiol
, vol.32
, pp. 223-236
-
-
Powell, S.K.1
Rivas, R.J.2
Rodriguez-Boulan, E.3
Hatten, M.E.4
-
55
-
-
3342895823
-
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
-
Sarbassov, D. D., Ali, S. M., Kim, D. H., Guertin, D. A., Latek, R. R., Erdjument-Bromage, H., Tempst, P. and Sabatini, D. M. (2004). Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr. Biol. 14, 1296-1302.
-
(2004)
Curr. Biol
, vol.14
, pp. 1296-1302
-
-
Sarbassov, D.D.1
Ali, S.M.2
Kim, D.H.3
Guertin, D.A.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
56
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
Sarbassov, D. D., Guertin, D. A., Ali, S. M. and Sabatini, D. M. (2005). Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307, 1098-1101.
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
57
-
-
0037428076
-
Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity
-
Shi, S. H., Jan, L. Y. and Jan, Y. N. (2003). Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity. Cell 112, 63-75.
-
(2003)
Cell
, vol.112
, pp. 63-75
-
-
Shi, S.H.1
Jan, L.Y.2
Jan, Y.N.3
-
58
-
-
12444296522
-
The human tumour suppressor PTEN regulates longevity and dauer formation in Caenorhabditis elegans
-
Solari, F., Bourbon-Piffaut, A., Masse, I., Payrastre, B., Chan, A. M. and Billaud, M. (2005). The human tumour suppressor PTEN regulates longevity and dauer formation in Caenorhabditis elegans. Oncogene 24, 20-27.
-
(2005)
Oncogene
, vol.24
, pp. 20-27
-
-
Solari, F.1
Bourbon-Piffaut, A.2
Masse, I.3
Payrastre, B.4
Chan, A.M.5
Billaud, M.6
-
59
-
-
33748295795
-
Insulin signaling in the central nervous system: Learning to survive
-
van der Heide, L. P., Ramakers, G. M. and Smidt, M. P. (2006). Insulin signaling in the central nervous system: learning to survive. Prog. Neurobiol. 79, 205-221.
-
(2006)
Prog Neurobiol
, vol.79
, pp. 205-221
-
-
van der Heide, L.P.1
Ramakers, G.M.2
Smidt, M.P.3
-
60
-
-
37149046442
-
Function of PTEN during the formation and maintenance of neuronal circuits in the brain
-
van Diepen, M. T. and Eickholt, B. J. (2008). Function of PTEN during the formation and maintenance of neuronal circuits in the brain. Dev. Neurosci. 30, 59-64.
-
(2008)
Dev. Neurosci
, vol.30
, pp. 59-64
-
-
van Diepen, M.T.1
Eickholt, B.J.2
-
61
-
-
0030805703
-
Phosphoinositide 3-kinases: A conserved family of signal transducers
-
Vanhaesebroeck, B., Leevers, S. J., Panayotou, G. and Waterfield, M. D. (1997). Phosphoinositide 3-kinases: a conserved family of signal transducers. Trends Biochem. Sci. 22, 267-272.
-
(1997)
Trends Biochem. Sci
, vol.22
, pp. 267-272
-
-
Vanhaesebroeck, B.1
Leevers, S.J.2
Panayotou, G.3
Waterfield, M.D.4
-
62
-
-
0034911881
-
Synthesis and function of 3-phosphorylated inositol lipids
-
Vanhaesebroeck, B., Leevers, S. J., Ahmadi, K., Timms, J., Katso, R., Driscoll, P. C., Woscholski, R., Parker, P. J. and Waterfield, M. D. (2001). Synthesis and function of 3-phosphorylated inositol lipids. Annu. Rev. Biochem. 70, 535-602.
-
(2001)
Annu Rev. Biochem
, vol.70
, pp. 535-602
-
-
Vanhaesebroeck, B.1
Leevers, S.J.2
Ahmadi, K.3
Timms, J.4
Katso, R.5
Driscoll, P.C.6
Woscholski, R.7
Parker, P.J.8
Waterfield, M.D.9
-
63
-
-
79952114000
-
The neurodevelopmental implications of PI3K signaling
-
Waite, K. and Eickholt, B. J. (2010). The neurodevelopmental implications of PI3K signaling. Curr. Top. Microbiol. Immunol. 346, 245-265.
-
(2010)
Curr. Top. Microbiol. Immunol
, vol.346
, pp. 245-265
-
-
Waite, K.1
Eickholt, B.J.2
-
64
-
-
2942596447
-
Genomic cis-regulatory architecture and trans-acting regulators of a single interneuron-specific gene battery in C. elegans
-
Wenick, A. S. and Hobert, O. (2004). Genomic cis-regulatory architecture and trans-acting regulators of a single interneuron-specific gene battery in C. elegans. Dev. Cell 6, 757-770.
-
(2004)
Dev. Cell
, vol.6
, pp. 757-770
-
-
Wenick, A.S.1
Hobert, O.2
-
65
-
-
0002221492
-
The structure of the nervous system of the nematode Caenorhabditis elegans
-
White, J. G., Southgate, E., Thomson, J. N. and Brenner, S. (1986). The structure of the nervous system of the nematode Caenorhabditis elegans. Philos. Trans. R. Soc. Lond. B Biol. Sci. 314, 1-340.
-
(1986)
Philos. Trans. R. Soc. Lond. B Biol. Sci
, vol.314
, pp. 1-340
-
-
White, J.G.1
Southgate, E.2
Thomson, J.N.3
Brenner, S.4
-
66
-
-
0142150016
-
Investigating C. elegans development through mosaic analysis
-
Yochem, J. and Herman, R. K. (2003). Investigating C. elegans development through mosaic analysis. Development 130, 4761-4768.
-
(2003)
Development
, vol.130
, pp. 4761-4768
-
-
Yochem, J.1
Herman, R.K.2
-
67
-
-
65649149752
-
Regulation of neuronal cell death by MST1-FOXO1 signaling
-
Yuan, Z., Lehtinen, M. K., Merlo, P., Villen, J., Gygi, S. and Bonni, A. (2009). Regulation of neuronal cell death by MST1-FOXO1 signaling. J. Biol. Chem. 284, 11285-11292.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 11285-11292
-
-
Yuan, Z.1
Lehtinen, M.K.2
Merlo, P.3
Villen, J.4
Gygi, S.5
Bonni, A.6
-
68
-
-
60849109211
-
Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice
-
Zhou, J., Blundell, J., Ogawa, S., Kwon, C. H., Zhang, W., Sinton, C., Powell, C. M. and Parada, L. F. (2009). Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice. J. Neurosci. 29, 1773-1783.
-
(2009)
J. Neurosci
, vol.29
, pp. 1773-1783
-
-
Zhou, J.1
Blundell, J.2
Ogawa, S.3
Kwon, C.H.4
Zhang, W.5
Sinton, C.6
Powell, C.M.7
Parada, L.F.8
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