Insulin secretory deficiency and glucose intolerance in Rab3A Null mice

Journal of Biological Chemistry

Volumn 278, Issue 11, 2003, Pages 9715-9721

  Yaekura, Kazuro ^a   Julyan, Richard ^a   Wicksteed, Barton L ^a   Hays, Lori B ^a   Alarcon, Cristina ^a   Sommers, Scott ^a   Poitout, Vincent ^a   Baskin, Denis G ^a   Wang, Yong ^c   Philipson, Louis H ^c   Rhodes, Christopher J ^a,b,d  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d PACIFIC NORTHWEST RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; FATTY ACIDS; GLUCOSE; OXIDATION;

DIABETES;

INSULIN;

ARGININE; GLUCOSE; GUANINE NUCLEOTIDE BINDING PROTEIN; INSULIN; PROTEIN; PROTEIN RAB3A; UNCLASSIFIED DRUG; MESSENGER RNA; OXYGEN; PROINSULIN; RAB PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; EXOCYTOSIS; GLUCOSE INTOLERANCE; GLUCOSE OXIDATION; HYPERGLYCEMIA; INSULIN RELEASE; INSULIN RESISTANCE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PHENOTYPE; PRIORITY JOURNAL; SECRETORY GRANULE; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; PANCREAS ISLET; TIME; TRANSGENIC MOUSE;

ANIMALIA;

ANIMALS; ARGININE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXOCYTOSIS; GLUCOSE; GLUCOSE INTOLERANCE; HYPERGLYCEMIA; INSULIN; ISLETS OF LANGERHANS; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; OXYGEN; PHENOTYPE; PROINSULIN; RAB3A GTP-BINDING PROTEIN; RNA, MESSENGER; TIME FACTORS;

EID: 0038660725     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211352200     Document Type: Article

References (30)

1. Leahy, J. L. (1990) Diabetes Care 13, 992-1010
2. Lingohr, M. K., Buettner, R., and Rhodes, C. J. (2002) Trends Mol. Med. 8, 375-384
3. Kahn, S. E. (2001) J. Clin. Endocrinol. Metab. 86, 4047-4058
4. Prentki, M., Tornheim, K., and Corkey, B. E. (1997) Diabetologia 40, Suppl. 2, S32-S41
5. Easom, R. A. (2000) Semin. Cell Dev. Biol 11, 253-266
6. Jahn, R., and Südhof, T. C. (1999) Annu. Rev. Biochem. 68, 863-911
7. Wollheim, C. B., Lang, J., and Regazzi, R. (1996) Diabetes Rev. 4, 276-297
8. Regazzi, R., Ravazzola, M., Lezzi, M., Lang, J. C., Zahraoui, A., Andereggen, E., Morel, P., Takai, Y., and Wollheim, C. B. (1996) J. Cell Sci. 109, 2265-2273
9. Iezzi, M., Escher, G., Meda, P., Charollais, A., Baldini, G., Darchen, F., Wollheim, C. B., and Regazzi, R. (1999) Mol. Endocrinol. 13, 202-212
10. Zerial, M., and McBride, H. (2001) Nat. Rev. 2, 107-117
11. Geppert, M., Bolshakov, V. Y., Slegelbaum, S. A., Takei, K., De Camilli, P., Hammer, R. E., and Südhof, T. C. (1994) Nature 369, 493-497
12. Geppert, M., Goda, Y., Stevens, C. F., and Südhof, T. C. (1997) Nature 387, 810-814
13. Martin, T. F. J. (1994) Curr. Opin. Neurobiol. 4, 626-632
14. Briaud, I., Kelpe, C. L., Johnson, L. M., Tran, P. O., and Poitout, V. (2002) Diabetes 51, 662-668
15. Donelan, M., Julyan, R., Kajio, H., Hays, L., Easom, R., Morfini, G., Brady, S. T., and Rhodes, C. J. (2002) J. Biol. Chem. 277, 24232-24242
16. Ensinck, J. W., Baskin, D. G., Vahl, T. P., Vogel, R. E., Laschansky, E. C., Francis, B. H., Hoffman, R. C., Krakover, J. D., Stamm, M. R., Low, M. J., Rubinstein, M., Otero-Corchon, V., and D'Alessio, D. A. (2002) Endocrinology 143, 2599-2609
17. Skelly, R. H., Wicksteed, B. L., Antinozzi, P. A., and Rhodes, C. J. (2001) Diabetes 50, 1791-1798
18. Wicksteed, B., Herbert, T. P., Alarcón, C., Lingohr, M. L., Moss, L. G., and Rhodes, C. J. (2001) J. Biol. Chem. 276, 22553-22558
19. Roe, M. W., Worley, J. F., 3rd, Qian, F., Tamarina, N., Mittal, A. A., Dralyuk, F., Blair, N. T., Mertz, R. J., Philipson, L. H., and Dukes, I. D. (1998) J. Biol. Chem. 273, 10402-10410
20. Kido, Y., Burks, D. J., Withers, D., Bruning, J. C., Kahn, C. R., White, M. F., and Accili, D. (2000) J. Clin. Invest. 105, 199-205
21. Ashcroft, S. J. H. (1980) Diabetologia 18, 5-15
22. Ahren, B., and Taborsky, G. J. J. (1988) Acta Physiol. Scand. 132, 143-150
23. Ortiz-Alonso, F. J., Herman, W. H., Zobel, D. L., Perry, T. J., Smith, M. J., and Halter, J. B. (1991) Diabetes 40, 1194-1202
24. Drews, G., Debuyser, A., Nenquin, M., and Henquin, J. C. (1990) Endocrinology 126, 1646-1653
25. Debuyser, A., Drews, G., and Henquin, J. C. (1991) Pfluegers Arch. 419, 131-137
26. Malaisse, W. J., Pipeleers, D. G., and Levy, J. (1974) Biochim. Biophys. Acta 362, 121-128
27. Coppola, T., Perret-Menoud, V., Luthi, S., Farnsworth, C. C., Glomset, J. A., and Regazzi, R. (1999) EMBO J. 18, 5885-5891
28. Kajio, H., Olszewski, S., Rosner, P., Donelan, M., Geoghegan, K., and Rhodes, C. J. (2001) Diabetes 50, 2029-2040
29. Rorsman, P., Eliasson, L., Renstrom, E., Gromada, J., Barg, S., and Gopel, S. (2000) News Physiol. Sci. 15, 72-77
30. Laedtke, T., Kjems, L., Porksen, N., Schmitz, O., Veldhuis, J., Kao, P. C., and Butler, P. C. (2000) Am. J. Physiol. Endocrinol. Metab. 279, E520-E528