From oncoproteins/tumor suppressors to microRNAs, the newest therapeutic targets for pulmonary arterial hypertension

Journal of Molecular Medicine

Volumn 89, Issue 11, 2011, Pages 1089-1101

  Paulin, Roxane ^a   Courboulin, Audrey ^a   Barrier, Marjorie ^a   Bonnet, Sébastien ^a,b  

^a LAVAL UNIVERSITY   (Canada)

^b Université Laval   (Canada)

Author keywords

Cell signaling; Hypertension; miRNA; Oncogene; Pulmonary; Tumor suppressor

Indexed keywords

ANTINEOPLASTIC AGENT; BARDOXOLONE METHYL; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; BOSUTINIB; ENDOTHELIN 1; EPIDERMAL GROWTH FACTOR; INTERLEUKIN 6; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; OPB 31121; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE PIM 1; SARACATINIB; SGI 1776; SMAD PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ADVANCED CANCER; ANEMIA; ANTIOXIDANT ACTIVITY; APOPTOSIS; ASTHENIA; DIARRHEA; DOWN REGULATION; DRUG TOLERABILITY; GENE CONTROL; GENE MUTATION; GENE TARGETING; HUMAN; NONHODGKIN LYMPHOMA; NONHUMAN; PATHOGENESIS; PHENOTYPE; PROSTATE CANCER; PULMONARY HYPERTENSION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; SOLID TUMOR;

ANIMALS; APOPTOSIS; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; CELL PROLIFERATION; DOWN-REGULATION; GENETIC DISEASES, INBORN; HUMANS; HYPERTENSION, PULMONARY; MAP KINASE SIGNALING SYSTEM; MICRORNAS; MUSCLE, SMOOTH, VASCULAR; MUTATION; MYOCYTES, SMOOTH MUSCLE; NEOPLASMS; PROTO-ONCOGENE PROTEINS C-PIM-1; SRC-FAMILY KINASES; STAT3 TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEINS;

EID: 80755153114     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-011-0788-5     Document Type: Review

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