Immunochemical detection of cytochrome P450 enzymes in liver microsomes of 27 cynomolgus monkeys

Journal of Pharmacology and Experimental Therapeutics

Volumn 339, Issue 2, 2011, Pages 654-661

  Uehara, Shotaro ^a   Murayama, Norie ^c   Nakanishi, Yasuharu ^a   Zeldin, Darryl C ^b   Yamazaki, Hiroshi ^c   Uno, Yasuhiro ^a  

^a SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 1D; CYTOCHROME P450 2A; CYTOCHROME P450 2B6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C76; CYTOCHROME P450 2C9; CYTOCHROME P450 2D; CYTOCHROME P450 2E; CYTOCHROME P450 2E1; CYTOCHROME P450 2J; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; CONTROLLED STUDY; CROSS REACTION; DRUG METABOLISM; ENZYME ACTIVITY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROXYLATION; IMMUNOBLOTTING; IMMUNOCHEMISTRY; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; TRANSCRIPTION REGULATION;

ANIMALS; ANTICOAGULANTS; ARYL HYDROCARBON HYDROXYLASES; COUMARINS; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME ASSAYS; FEMALE; HUMANS; HYDROXYLATION; IMMUNOBLOTTING; MACACA FASCICULARIS; MALE; METABOLIC DETOXICATION, DRUG; MICROSOMES, LIVER; OXAZINES; SENSITIVITY AND SPECIFICITY; STEROID HYDROXYLASES;

EID: 80054786436     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.185009     Document Type: Article

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