-
1
-
-
0028802138
-
Isoflurane-chlorodifluoroethene interaction in human liver microsomes: Role of cytochrome P-4502B6 in potentiation of haloethene metabolism
-
Baker MT, Olson MJ, Wang Y, Ronnenberg WC Jr, Johnson JT and Brady AN (1995) Isoflurane-chlorodifluoroethene interaction in human liver microsomes: Role of cytochrome P-4502B6 in potentiation of haloethene metabolism. Drug Metab Dispos 23:60-64
-
(1995)
Drug Metab Dispos
, vol.23
, pp. 60-64
-
-
Baker, M.T.1
Olson, M.J.2
Wang, Y.3
Ronnenberg W.C., Jr.4
Johnson, J.T.5
Brady, A.N.6
-
3
-
-
0028864043
-
Production of a form-specific, inhibitory antibody against rat cytochrome P-450 2B1 using a synthetic peptide antigen against a putative substrate binding site
-
Charnecki J, Putt D, Kim EY and Kim H (1995) Production of a form-specific, inhibitory antibody against rat cytochrome P-450 2B1 using a synthetic peptide antigen against a putative substrate binding site. Biochem Biophys Res Commun 216:1024-1033.
-
(1995)
Biochem Biophys Res Commun
, vol.216
, pp. 1024-1033
-
-
Charnecki, J.1
Putt, D.2
Kim, E.Y.3
Kim, H.4
-
4
-
-
0030739223
-
Human cytochrome P-4502B6: Interindividual hepatic expression, substrate specificity and role in procarcinogen activation
-
Code EL, Crespi CL, Penman BW, Gonzalez FJ, Chang TKH and Waxman DJ (1997) Human cytochrome P-4502B6: Interindividual hepatic expression, substrate specificity and role in procarcinogen activation. Drug Metab Dispos 25:985-993.
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 985-993
-
-
Code, E.L.1
Crespi, C.L.2
Penman, B.W.3
Gonzalez, F.J.4
Chang, T.K.H.5
Waxman, D.J.6
-
5
-
-
0029073965
-
Anti-peptide antibodies against overlapping sequences differentially inhibit human CYP2D6
-
Cribb A, Nuss C and Wang R (1995) Anti-peptide antibodies against overlapping sequences differentially inhibit human CYP2D6 Drug Metab Dispos 23:671-675.
-
(1995)
Drug Metab Dispos
, vol.23
, pp. 671-675
-
-
Cribb, A.1
Nuss, C.2
Wang, R.3
-
6
-
-
0028315963
-
Quantification ofCYP2B7, CYP4B1 and CYPOR messenger RNAs in normal human lung and lung tumors
-
Czerwinski M, McLemore TL, Gelboin HV and Gonzalez FJ (1994) Quantification ofCYP2B7, CYP4B1 and CYPOR messenger RNAs in normal human lung and lung tumors. Cancer Res 54:1085-1091.
-
(1994)
Cancer Res
, vol.54
, pp. 1085-1091
-
-
Czerwinski, M.1
McLemore, T.L.2
Gelboin, H.V.3
Gonzalez, F.J.4
-
7
-
-
0031661240
-
Development of a comprehensive panel of antibodies against the major xenobiotic metabolising forms of cytochrome P-450 in humans
-
Edwards RJ, Adams DA, Watts PS, Davies DS and Boobis AR (1998) Development of a comprehensive panel of antibodies against the major xenobiotic metabolising forms of cytochrome P-450 in humans. Biochem Pharmacol 56:377-387
-
(1998)
Biochem Pharmacol
, vol.56
, pp. 377-387
-
-
Edwards, R.J.1
Adams, D.A.2
Watts, P.S.3
Davies, D.S.4
Boobis, A.R.5
-
8
-
-
0032160463
-
Further characterization of the expression in liver and catalytic activity of CYP2B6
-
Ekins S, VandenBranden M, Ring BJ, Gillespie JS, Yang TJ, Gelboin HV and Wrighton SA (1998) Further characterization of the expression in liver and catalytic activity of CYP2B6. J Pharmacol Exp Ther 266:1253-1259.
-
(1998)
J Pharmacol Exp Ther
, vol.266
, pp. 1253-1259
-
-
Ekins, S.1
VandenBranden, M.2
Ring, B.J.3
Gillespie, J.S.4
Yang, T.J.5
Gelboin, H.V.6
Wrighton, S.A.7
-
10
-
-
0022249654
-
Induction of hepatitis A virus-neutralizing antibody by a virus-specific synthetic peptide
-
Emini EA, Hughes JV, Perlow DS and Boger J (1985) Induction of hepatitis A virus-neutralizing antibody by a virus-specific synthetic peptide. J Virol 55:836-839.
-
(1985)
J Virol
, vol.55
, pp. 836-839
-
-
Emini, E.A.1
Hughes, J.V.2
Perlow, D.S.3
Boger, J.4
-
11
-
-
0026542525
-
Relative expression of cytochrome P-450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics
-
Forrester LM, Henderson CJ, Glancey MJ, Black DJ, Park BK, Ball SE, Kitteringham NR, McLaren AW, Miles JS, Skett P and Wolf CR (1992) Relative expression of cytochrome P-450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics. Biochem J 281:359-368.
-
(1992)
Biochem J
, vol.281
, pp. 359-368
-
-
Forrester, L.M.1
Henderson, C.J.2
Glancey, M.J.3
Black, D.J.4
Park, B.K.5
Ball, S.E.6
Kitteringham, N.R.7
McLaren, A.W.8
Miles, J.S.9
Skett, P.10
Wolf, C.R.11
-
12
-
-
0022372258
-
The structure of phenobarbital-inducible rat liver cytochrome P-450 isoenzyme PB-4. Production and characterization of site-specific antibodies
-
Frey AB, Waxman DJ and Kreibich G (1985) The structure of phenobarbital-inducible rat liver cytochrome P-450 isoenzyme PB-4. Production and characterization of site-specific antibodies. J Biol Chem 260:15253-15265.
-
(1985)
J Biol Chem
, vol.260
, pp. 15253-15265
-
-
Frey, A.B.1
Waxman, D.J.2
Kreibich, G.3
-
13
-
-
0028210653
-
The influence of aging on the metabolism of simultaneously administered hexobarbital enantiomers and antipyrine before and after phenobarbital induction in male rats: A longitudinal study
-
Groen K, Breimer DD, Jansen EJ and van Bezooijen CF (1994) The influence of aging on the metabolism of simultaneously administered hexobarbital enantiomers and antipyrine before and after phenobarbital induction in male rats: A longitudinal study. J Pharmacol Exp Ther 268:531-536.
-
(1994)
J Pharmacol Exp Ther
, vol.268
, pp. 531-536
-
-
Groen, K.1
Breimer, D.D.2
Jansen, E.J.3
Van Bezooijen, C.F.4
-
14
-
-
0002888510
-
Human cytochrome P-450 enzymes
-
Ortiz de Montellano PR ed Plenum Press, New York
-
Guengerich, FP (1995) Human cytochrome P-450 enzymes, in Cytochrome P-450 (Ortiz de Montellano PR ed) pp 473-535, Plenum Press, New York.
-
(1995)
Cytochrome P-450
, pp. 473-535
-
-
Guengerich, F.P.1
-
16
-
-
0029833258
-
Catalytic role of cytochrome P-4502B6 in the V-demethylation of S-mephenytoin
-
Heyn H, White RB and Stevens JC (1996) Catalytic role of cytochrome P-4502B6 in the V-demethylation of S-mephenytoin. Drug Matab Dispos 24:948-954.
-
(1996)
Drug Matab Dispos
, vol.24
, pp. 948-954
-
-
Heyn, H.1
White, R.B.2
Stevens, J.C.3
-
17
-
-
0029971798
-
Multiple forms of human P-450 expressed in Saccharomyces cerevisiae
-
Imaoka S, Yamada T, Hiroi T, Hayashi K, Sakaki T, Yabsaki Y and Funae Y (1996) Multiple Forms of Human P-450 Expressed in Saccharomyces cerevisiae. Biochem Pharmacol 51: 1041-1050.
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 1041-1050
-
-
Imaoka, S.1
Yamada, T.2
Hiroi, T.3
Hayashi, K.4
Sakaki, T.5
Yabsaki, Y.6
Funae, Y.7
-
18
-
-
0030878442
-
Cytochrome P-450 isozymes responsible for the metabolism of toluene and styrene in human liver microsomes
-
Kim H, Wang RS, Elovaara E, Raunio H, Pelkonen O, Aoyama T, Vanio H and Nakajima T (1997) Cytochrome P-450 isozymes responsible for the metabolism of toluene and styrene in human liver microsomes. Xenobiotica 27:657-666.
-
(1997)
Xenobiotica
, vol.27
, pp. 657-666
-
-
Kim, H.1
Wang, R.S.2
Elovaara, E.3
Raunio, H.4
Pelkonen, O.5
Aoyama, T.6
Vanio, H.7
Nakajima, T.8
-
20
-
-
0031845066
-
Human N-demethylation of (S)-mephenytoin by cytochrome P-450s 2C9 and 2B6
-
Ko J-W, Desta Z and Flockhart DA (1998) Human N-demethylation of (S)-mephenytoin by cytochrome P-450s 2C9 and 2B6. Drug Metab Dispos 26:775-778.
-
(1998)
Drug Metab Dispos
, vol.26
, pp. 775-778
-
-
Ko, J.-W.1
Desta, Z.2
Flockhart, D.A.3
-
21
-
-
0020475449
-
A simple method for displaying the hydropathic character of a protein
-
Kyte J and Doolittle RJ (1982) A simple method for displaying the hydropathic character of a protein. Mol Biol 157:105-132.
-
(1982)
Mol Biol
, vol.157
, pp. 105-132
-
-
Kyte, J.1
Doolittle, R.J.2
-
23
-
-
0031877729
-
The CYP2 family: Models, mutants and interactions
-
Lewis DFV (1998) The CYP2 family: Models, mutants and interactions. Xenobiotica 28:617-661.
-
(1998)
Xenobiotica
, vol.28
, pp. 617-661
-
-
Lewis, D.F.V.1
-
24
-
-
0025992973
-
LKM-1 autoantibodies recognize a short linear sequence in P-450IID6, a cytochrome P-450 monooxygenase
-
Manns MP, Griffin KJ, Sullivan KF and Johnson EF (1991) LKM-1 autoantibodies recognize a short linear sequence in P-450IID6, a cytochrome P-450 monooxygenase. J Clin Invest 88:1370-1378.
-
(1991)
J Clin Invest
, vol.88
, pp. 1370-1378
-
-
Manns, M.P.1
Griffin, K.J.2
Sullivan, K.F.3
Johnson, E.F.4
-
25
-
-
0023147728
-
A simple, non-chromatographic procedure to purify immunoglobulins from serum and ascites fluid
-
McKinney MM and Parkinson A (1987) A simple, non-chromatographic procedure to purify immunoglobulins from serum and ascites fluid. J Immunol Methods 96:271-278.
-
(1987)
J Immunol Methods
, vol.96
, pp. 271-278
-
-
McKinney, M.M.1
Parkinson, A.2
-
26
-
-
0023901028
-
A novel human cytochrome P-450 gene (P-450IIB): Chromosomal localization and evidence for alternative splicing
-
Miles JS, Spurr NK, Gough AC, Jowett T, McLaren AW, Brook JD and Wolf CR (1988) A novel human cytochrome P-450 gene (P-450IIB): Chromosomal localization and evidence for alternative splicing. Nucleic Acids Res 16:5783-5795.
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 5783-5795
-
-
Miles, J.S.1
Spurr, N.K.2
Gough, A.C.3
Jowett, T.4
McLaren, A.W.5
Brook, J.D.6
Wolf, C.R.7
-
27
-
-
0027519429
-
Characterization of cytochrome P-450 2B6 in human liver microsomes
-
Mimura M, Baba T, Yamazaki H, Ohmori S, Inui Y, Gonzalez FJ, Guengerich FP and Shimada T (1993) Characterization of cytochrome P-450 2B6 in human liver microsomes. Drug Metab Dispos 21:1048-1056.
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 1048-1056
-
-
Mimura, M.1
Baba, T.2
Yamazaki, H.3
Ohmori, S.4
Inui, Y.5
Gonzalez, F.J.6
Guengerich, F.P.7
Shimada, T.8
-
28
-
-
0030056594
-
Specificity of substrate and inhibitor probes for cytochrome P-450s: Evaluation of in vitro metabolism using cDNA-expressed human P-450s and human liver microsomes
-
Ono S, Hatanaka T, Hotta H, Satoh T, Gonzalez FJ and Tsutsui M (1996) Specificity of substrate and inhibitor probes for cytochrome P-450s: Evaluation of in vitro metabolism using cDNA-expressed human P-450s and human liver microsomes. Xenobiotica 26:681-693.
-
(1996)
Xenobiotica
, vol.26
, pp. 681-693
-
-
Ono, S.1
Hatanaka, T.2
Hotta, H.3
Satoh, T.4
Gonzalez, F.J.5
Tsutsui, M.6
-
29
-
-
0031568856
-
Targeted antipeptide antibodies t cytochrome P-450 2C18 based on epitope mapping of an inhibitory monoclonal antibody to P-450 2C5
-
Richardson TH, Griffin KJ, Jung F, Raucy JL and Johnson EF (1997) Targeted antipeptide antibodies t cytochrome P-450 2C18 based on epitope mapping of an inhibitory monoclonal antibody to P-450 2C5. Arch Biochem Biophys 338:157-164.
-
(1997)
Arch Biochem Biophys
, vol.338
, pp. 157-164
-
-
Richardson, T.H.1
Griffin, K.J.2
Jung, F.3
Raucy, J.L.4
Johnson, E.F.5
-
30
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
Shimada T, Yamazaki H, Mimura M, Inui Y and Guengerich FP (1994) Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 270:414-423.
-
(1994)
J Pharmacol Exp Ther
, vol.270
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
Inui, Y.4
Guengerich, F.P.5
-
32
-
-
0029671245
-
Ring hydroxylation of [o-3H]methoxychlor as a probe for liver microsomal CYP2B activity: A potential assay for CYP2B in vivo
-
Stresser DM, Dehal SS and Kupfer D (1996) Ring hydroxylation of [o-3H]methoxychlor as a probe for liver microsomal CYP2B activity: A potential assay for CYP2B in vivo. Ana! Biochem 233:100-107.
-
(1996)
Ana! Biochem
, vol.233
, pp. 100-107
-
-
Stresser, D.M.1
Dehal, S.S.2
Kupfer, D.3
-
33
-
-
0031043595
-
Catalytic characteristics of CYP3A4: Requirement for a phenolic function in ortho-hydroxylation of estradiol and mono-O-demethylated methoxychlor
-
Stresser DM and Kupfer D (1997) Catalytic characteristics of CYP3A4: Requirement for a phenolic function in ortho-hydroxylation of estradiol and mono-O-demethylated methoxychlor. Biochemistry 36:2203-2210.
-
(1997)
Biochemistry
, vol.36
, pp. 2203-2210
-
-
Stresser, D.M.1
Kupfer, D.2
-
34
-
-
0032101172
-
Prosubstrates of CYP3A4, the major human hepatic cytochrome P-450: Transformation into substrates for other P-450 isoforms
-
Stresser DM and Kupfer D (1998a) Prosubstrates of CYP3A4, the major human hepatic cytochrome P-450: Transformation into substrates for other P-450 isoforms. Biochem Pharmacol 55:1861-1871.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1861-1871
-
-
Stresser, D.M.1
Kupfer, D.2
-
35
-
-
0031657035
-
Human cytochrome P-450 catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen: Role of CYP2C19 and CYP1A2 in O-demethylation
-
Stresser DM and Kupfer D (1998b) Human cytochrome P-450 catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen: Role of CYP2C19 and CYP1A2 in O-demethylation. Drug Metab Dispos 26:868-874.
-
(1998)
Drug Metab Dispos
, vol.26
, pp. 868-874
-
-
Stresser, D.M.1
Kupfer, D.2
-
36
-
-
0031452340
-
A comparison of hepatic cytochromc P-450 protein expression between infancy and postinfancy
-
Tateishi T, Nakura H, Asoh M, Watanabe M, Tanak M, Kumai T, Takashima S, Imaoka S, Funae Y, Yabusaki Y, Kamataki T and Kobayashi S (1997) A comparison of hepatic cytochromc P-450 protein expression between infancy and postinfancy. Life Sci 61:2567-2574.
-
(1997)
Life Sci
, vol.61
, pp. 2567-2574
-
-
Tateishi, T.1
Nakura, H.2
Asoh, M.3
Watanabe, M.4
Tanak, M.5
Kumai, T.6
Takashima, S.7
Imaoka, S.8
Funae, Y.9
Yabusaki, Y.10
Kamataki, T.11
Kobayashi, S.12
-
37
-
-
0009482260
-
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Procedure and some applications
-
Towbin H, Staehelin T and Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Procedure and some applications. Proc Natl Acad Sci USA 76:4350-4354.
-
(1979)
Proc Natl Acad Sci USA
, vol.76
, pp. 4350-4354
-
-
Towbin, H.1
Staehelin, T.2
Gordon, J.3
-
38
-
-
0030923770
-
Inhibitory anti-peptide antibody against human CYP3A4
-
Wang R and Lu A (1997) Inhibitory anti-peptide antibody against human CYP3A4. Drug Metab Dispos 25:762-767.
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 762-767
-
-
Wang, R.1
Lu, A.2
-
39
-
-
0024464027
-
cDNA cloning and sequence and cdna-directed expression of human P-450 IIB1: Identification on chromosome 19 and differential expression of the IIB mRNAs in human liver
-
Yamano S, Nhamburo PT, Aoyama T, Meyer UA, Inaba T, Kalow W, Gelboin HV, McBride OW and Gonzalez FJ (1989) cDNA cloning and sequence and cDNA-directed expression of human P-450 IIB1: Identification on chromosome 19 and differential expression of the IIB mRNAs in human liver. Biochemistry 28:7340-7348.
-
(1989)
Biochemistry
, vol.28
, pp. 7340-7348
-
-
Yamano, S.1
Nhamburo, P.T.2
Aoyama, T.3
Meyer, U.A.4
Inaba, T.5
Kalow, W.6
Gelboin, H.V.7
McBride, O.W.8
Gonzalez, F.J.9
-
40
-
-
0030064194
-
7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P-4501A2 and 2E1 in human liver microsomes
-
Yamazaki H, Inoue K, Mimura M, Oda Y, Guengerich FP and Shimada T (1996) 7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P-4501A2 and 2E1 in human liver microsomes. Biochem Pharmacol 51:313-319.
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 313-319
-
-
Yamazaki, H.1
Inoue, K.2
Mimura, M.3
Oda, Y.4
Guengerich, F.P.5
Shimada, T.6
-
41
-
-
0032525032
-
An inhibitory monoclonal antibody to human cytochrome P-450 2B6
-
Yang TJ, Krausz KW, Shou M, Yang SK, Buters JTM, Gonzalez FJ and Gelboin HV (1998) An inhibitory monoclonal antibody to human cytochrome P-450 2B6. Biochem Pharmacol 55: 1633-1640.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1633-1640
-
-
Yang, T.J.1
Krausz, K.W.2
Shou, M.3
Yang, S.K.4
Buters, J.T.M.5
Gonzalez, F.J.6
Gelboin, H.V.7
|