Cynomolgus monkey CYP2D44 newly identified in liver, metabolizes bufuralol, and dextromethorphan

Drug Metabolism and Disposition

Volumn 38, Issue 9, 2010, Pages 1486-1492

  Uno, Yasuhiro ^a   Uehara, Shotaro ^a   Kohara, Sakae ^a   Murayama, Norie ^b   Yamazaki, Hiroshi ^b  

^a SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BUFURALOL; COMPLEMENTARY DNA; CYTOCHROME P450; CYTOCHROME P450 2D17; CYTOCHROME P450 2D44; DEXTROMETHORPHAN; MESSENGER RNA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DEMETHYLATION; DRUG METABOLISM; ESCHERICHIA COLI; FEMALE; GENE AMPLIFICATION; GENE CLUSTER; GENE DOSAGE; GENE EXPRESSION; GENE IDENTIFICATION; GENOME; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHESUS MONKEY; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CYTOCHROME P-450 ENZYME SYSTEM; DEXTROMETHORPHAN; DNA PRIMERS; DNA, COMPLEMENTARY; ETHANOLAMINES; EXONS; INTRONS; MACACA FASCICULARIS; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID;

ESCHERICHIA COLI; MACACA FASCICULARIS; MACACA MULATTA; MARMOSETS; PRIMATES;

EID: 77956005186     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.110.033274     Document Type: Article

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