A novel CYP2A26 identified in cynomolgus monkey liver metabolizes coumarin

Xenobiotica

Volumn 40, Issue 9, 2010, Pages 621-629

  Uehara, Shotaro ^a   Murayama, Norie ^b   Yamazaki, Hiroshi ^b   Uno, Yasuhiro ^a  

^a SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Cynomolgus monkey; CYP2A; Cytochrome P450; Drug metabolism; Liver

Indexed keywords

COMPLEMENTARY DNA; COUMARIN; CYTOCHROME P450 2A; CYTOCHROME P450 2A13; CYTOCHROME P450 2A23; CYTOCHROME P450 2A24; CYTOCHROME P450 2A26; CYTOCHROME P450 2A6; MESSENGER RNA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CYNOMOLGUS MONKEY; DRUG HYDROXYLATION; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME MECHANISM; FEMALE; GENE EXPRESSION PROFILING; IMMUNOBLOTTING; LIVER METABOLISM; MACACA; MALE; MOLECULAR EVOLUTION; MONKEY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; RAT; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; COUMARINS; CYTOCHROME P-450 ENZYME SYSTEM; DNA, COMPLEMENTARY; DOGS; EXONS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTRONS; LIVER; MACACA FASCICULARIS; MALE; MICE; MOLECULAR SEQUENCE DATA; PHYLOGENY; RATS; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA;

ANIMALIA; CANIS FAMILIARIS; ESCHERICHIA COLI; MACACA FASCICULARIS; RATTUS;

EID: 77955596754     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2010.501118     Document Type: Article

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