Newly identified CYP2C93 is a functional enzyme in rhesus monkey, but not in cynomolgus monkey

PLoS ONE

Volumn 6, Issue 2, 2011, Pages

  Uno, Yasuhiro ^a   Uehara, Shotaro ^a   Kohara, Sakae ^a   Iwasaki, Kazuhide ^a   Nagata, Ryoichi ^a   Fukuzaki, Koichiro ^a   Utoh, Masahiro ^a   Murayama, Norie ^b   Yamazaki, Hiroshi ^b  

^a SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; COMPLEMENTARY DNA; CYTOCHROME P450 2C; CYTOCHROME P450 2C93; DICLOFENAC; DRUG METABOLIZING ENZYME; FLURBIPROFEN; GUANINE; MEPHENYTOIN; MESSENGER RNA; PACLITAXEL; THYMINE; TOLBUTAMIDE; UNCLASSIFIED DRUG; CYTOCHROME P 450 CYP2C SUBFAMILY; CYTOCHROME P-450 CYP2C SUBFAMILY; CYTOCHROME P450; DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CODON; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME LOCALIZATION; ENZYME METABOLISM; ESCHERICHIA COLI; EXON SKIPPING; FEMALE; FRAMESHIFT MUTATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOTYPE; HETEROLOGOUS EXPRESSION; HUMAN; INTRON; LIVER; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; NULL ALLELE; OPEN READING FRAME; PROTEIN EXPRESSION; RHESUS MONKEY; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; EXON; GENE EXPRESSION REGULATION; GENETICS; GENOMICS; GENOTYPING TECHNIQUE; MACACA FASCICULARIS; MACACA MULATTA; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MULTIGENE FAMILY; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE;

ESCHERICHIA COLI; MACACA FASCICULARIS; MACACA MULATTA;

AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; DNA, COMPLEMENTARY; EXONS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENOMICS; GENOTYPING TECHNIQUES; HUMANS; MACACA FASCICULARIS; MACACA MULATTA; MALE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PHARMACEUTICAL PREPARATIONS; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY;

EID: 79951558815     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016923     Document Type: Article

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